Comment Period Extended to 3/23/2015 for Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials
151 studies found for:    Open Studies | "Anemia, Sickle Cell"
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Rank Status Study
1 Recruiting Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Severe Congenital Anemias Including Sickle Cell Disease and Beta-Thalassemia
Conditions: Peripheral Blood Stem Cell Transplantation;   Anemia, Sickle Cell;   Graft-Versus-Host Disease;   Sirolimus (Rapamune );   Alemtuzumab (Campath )
Interventions: Procedure: PBMC Transplant;   Drug: Alemtuzumab (Campath  );   Drug: Sirolimus (Rapamune  );   Drug: Cyclophosphamide (Cytoxan  );   Procedure: Low Dose Irradiation
2 Recruiting Decision Aid for Therapeutic Options In Sickle Cell Disease
Conditions: Sickle Cell Disease;   Sickle Cell Anemia;   Hemoglobin SS;   Hemoglobin SC;   Hemoglobin Beta Thalassemia
Interventions: Other: Decision Aid;   Other: Standard Practice
3 Unknown  Clinical Importance of Treating Iron Overload in Sickle Cell Disease
Conditions: Anemia, Sickle Cell;   Transfusion Hemochromatosis
Intervention: Drug: deferasirox
4 Not yet recruiting Efficacy and Safety of Rivipansel (GMI-1070) in the Treatment of Vaso-Occlusive Crisis in Hospitalized Subjects With Sickle Cell Disease
Condition: Anemia, Sickle Cell
Interventions: Drug: Rivipansel;   Other: Placebo
5 Unknown  A Randomized Trial of LOVAZA in Pediatric Sickle Cell Disease (SCD)
Conditions: Sickle Cell Disease;   HEMOGLOBIN SS;   Hemoglobin S Beta-0 Thalassemia;   Inflammation;   Quality of Life
Interventions: Dietary Supplement: Omega-3 Fatty Acids: Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA);   Other: Placebo Capsules
6 Not yet recruiting Hematopoietic Stem Cell Transplant for Sickle Cell Disease
Conditions: Sickle Cell Disease;   Sickle Cell Anemia;   SCD
Interventions: Drug: Fludarabine;   Procedure: Hematopoietic Stem Cell Transplant (HSCT)
7 Recruiting Microvascular Blood Flow in Sickle Cell Anemia
Conditions: Sickle Cell Disease;   Sickle Cell Anemia
Interventions: Drug: regadenoson infusion with contrast-enhanced ultrasound;   Procedure: contrast-enhanced ultrasound
8 Recruiting Gene Transfer for Patients With Sickle Cell Disease
Conditions: Sickle Cell Disease;   Sickle Cell Anemia
Intervention: Genetic: Gene transfer
9 Recruiting Sickle Cell Disease - Stroke Prevention in Nigeria Trial
Conditions: Sickle Cell Anemia;   Sickle Cell Disease;   Stroke
Intervention: Drug: Hydroxyurea
10 Recruiting Secondary Pulmonary Hypertension in Adults With Sickle Cell Anemia
Conditions: Pulmonary Hypertension;   Sickle Cell Anemia;   Sickle Cell Disease
Intervention:
11 Unknown  Arginine Treatment of Acute Chest Syndrome (Pneumonia) in Sickle Cell Disease Patients
Conditions: Anemia, Sickle Cell;   Pneumonia
Intervention: Drug: Arginine hydrochloride
12 Recruiting Efficacy of Vorinostat to Induce Fetal Hemoglobin in Sickle Cell Disease
Conditions: Sickle Cell Disease;   Sickle Cell Anemia
Intervention: Drug: vorinostat
13 Unknown  Iron Mediated Vascular Disease in Sickle Cell Anemia Patients
Condition: Sickle Cell Disease
Intervention:
14 Recruiting N-Acetylcysteine in Patients With Sickle Cell Disease
Condition: Sickle Cell Disease
Interventions: Drug: N-Acetylcysteine;   Drug: Placebo
15 Not yet recruiting Preventing Sickle Cell Kidney Disease
Conditions: Anemia, Sickle Cell;   Sickle Cell Disease;   Kidney Disease;   Hypertension;   Proteinuria
Intervention: Drug: Losartan
16 Unknown  Cardiovascular Complications of Sickle Cell Disease
Condition: Sickle Cell Disease
Intervention: Procedure: MRI, Transthoracic Echocardiography, tonometry, EKG
17 Recruiting Liver Fibrosis in Sickle Cell Disease
Condition: Sickle Cell Disease
Interventions: Other: Liver transient elastography (Fibroscan);   Other: Ferriscan;   Procedure: Liver biopsy
18 Recruiting Screening Patients With Sickle Cell Disease for Kidney Damage
Condition: Sickle Cell Disease
Intervention:
19 Recruiting Molecular Phenotyping of Asthma in Sickle Cell Disease
Conditions: Sickle Cell Disease;   Asthma
Intervention:
20 Not yet recruiting Androgen Regulation of Priapism in Sickle Cell Disease
Conditions: Priapism;   Sickle Cell Disease
Intervention: Drug: Transdermal Androgel

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Indicates status has not been verified in more than two years