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74 studies found for:    Open Studies | "Anemia, Aplastic"
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Open Studies | "Anemia, Aplastic" (74 records)
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Rank Status Study
1 Recruiting Efficacy and Safety of Eltrombopag + CSA in Patients With Moderate Aplastic Anemia (EMAA)
Condition: Anemia, Aplastic
Interventions: Drug: Eltrombopag;   Drug: Placebo (for Eltrombopag)
2 Not yet recruiting Efficacy and Safety of Thrombopoietin In Patients With Severe and Very Severe Aplastic Anemia
Condition: Anemia, Aplastic
Interventions: Drug: rhTPO;   Drug: placebo
3 Recruiting Safety and Efficacy of Patient's Own AD-MSC and AD-HSC Transplantation in Patients With Severe Aplastic Anemia
Condition: Severe Aplastic Anemia
Interventions: Drug: Rabbit antithymoglobulin (ATG);   Procedure: Adipose derived mesenchymal stem cells ( AD-MSCs);   Procedure: AD-MSC transdifferentiated HSCs (AD-HSCs)
4 Recruiting Comparison of Two Different Doses of Rabbit ATG-Fresenius With Cyclosporin in the Treatment of Acquired Aplastic Anaemia
Condition: Aplastic Anemia
Intervention: Drug: ATG-fresenius
5 Recruiting The Efficacy of Immunosuppressive Therapy Combined With Cord Blood Transfusion in Treatment of Severe Aplastic Anemia
Condition: Severe Aplastic Anemia
Interventions: Procedure: IST;   Biological: cord blood transfusion;   Drug: Thymoglobuline® and oral CSA
6 Recruiting A Phase 2 Study to Evaluate the Efficacy and Safety of AMG531 in Aplastic Anemia
Condition: Aplastic Anemia
Intervention: Drug: AMG531
7 Not yet recruiting A Phase II Dose-escalation Study Characterizing the PK of Eltrombopag in Pediatric Patients With Previously Untreated or Relapsed Severe Aplastic Anemia or Recurrent Aplastic Anemia
Condition: Aplastic Anemia
Interventions: Drug: Eltrombopag;   Drug: hATG;   Drug: CsA
8 Not yet recruiting Optimizing Cord Blood and Haploidentical Aplastic Anemia Transplantation (BMT CTN 1502)
Condition: Severe Aplastic Anemia
Interventions: Drug: Antithymocyte Globulin;   Drug: Fludarabine;   Drug: Cyclophosphamide;   Radiation: Total Body Irradiation (TBI);   Procedure: UCB HSCT;   Procedure: Haplo HSCT;   Drug: Tacrolimus;   Drug: Mycophenolate mofetil (MMF);   Drug: G-CSF
9 Recruiting A Single-Arm Phase 2 Study With Optimized Standard Protocol for Severe Aplastic Anemia
Condition: Aplastic Anemia
Intervention: Drug: rabbit ATG, Cyclosporine, Levamisole
10 Recruiting Umbilical Cord Derived Mesenchymal Stem Cells Therapy in Aplastic Anemia
Condition: Aplastic Anemia
Intervention: Biological: mesenchymal stem cells
11 Not yet recruiting Eltrombopag Combined With Cyclosporine as First Line Therapy in Patients With Severe Acquired Aplastic Anemia
Condition: Severe Aplastic Anemia
Interventions: Drug: eltrombopag;   Drug: Cyclosporine
12 Not yet recruiting ATG Combined With Cyclophosphamide And Cord Blood Transfusion in Treating Patients With Severe Aplastic Anemia
Condition: Aplastic Anemia
Interventions: Drug: Rabbit ATG, (Genzyme);   Drug: Cy;   Drug: CsA;   Biological: Cord blood
13 Recruiting Unrelated Donor Transplant Versus Immune Therapy in Pediatric Severe Aplastic Anemia
Condition: Severe Aplastic Anemia
Interventions: Drug: cyclosporine;   Procedure: Matched Unrelated Donor Hematopoietic Stem Cell Transplant;   Drug: horse anti-thymocyte globulin (ATG);   Drug: rabbit anti-thymocyte globulin (ATG);   Drug: methotrexate;   Drug: fludarabine;   Drug: cyclophosphamide;   Radiation: low-dose total body irradiation (TBI);   Procedure: Immunosuppressive Therapy (IST)
14 Recruiting Haploidentical Bone Marrow Transplant With Post-Transplant Cyclophosphamide for Patients With Severe Aplastic Anemia
Condition: Severe Aplastic Anemia
Interventions: Drug: Fludarabine;   Drug: Cyclophosphamide;   Radiation: Total Body Irradiation;   Drug: Rabbit ATG
15 Recruiting Hematopoietic Stem Cell Transplant for Dyskeratosis Congenita or Severe Aplastic Anemia
Conditions: Dyskeratosis Congenita;   Aplastic Anemia
Interventions: Drug: Alemtuzumab;   Drug: Fludarabine;   Drug: Cyclophosphamide;   Radiation: Total Body Irradiation;   Biological: Stem Cell Transplant;   Drug: Anti-thymocyte globulin
16 Recruiting Sirolimus (Rapamune ) for Relapse Prevention in People With Severe Aplastic Anemia Responsive to Immunosuppressive Therapy
Condition: Severe Aplastic Anemia
Intervention: Drug: Sirolimus
17 Recruiting hATG+CsA vs hATG+CsA+Eltrombopag for SAA
Condition: Severe Aplastic Anemia
Interventions: Drug: hATG;   Drug: CsA;   Drug: Eltrombopag
18 Recruiting Randomised Study Comparing Different Dosages of Rabbit ATG in Patients With SAA
Condition: Acquired Aplastic Anemia.
Intervention: Drug: Thymoglobulin
19 Recruiting Phase IIA Open Label Study to Evaluate Efficacy and Safety of BL-8040 Followed by (hATG), Cyclosporine and Methyprednisolone in Adult Subjects With Aplastic Anemia or Hypoplastic Myelodysplastic Syndrome
Conditions: Aplastic Anemia;   Hypoplastic Myelodysplastic Syndrome
Interventions: Drug: BL-8040;   Drug: horse anti-thymocyte globulin (hATG);   Drug: Methylprednisolone;   Drug: Cyclosporine
20 Recruiting Stem Cell Transplant Using Peripheral and Cord Blood Stem Cells to Treat Severe Aplastic Anemia and Myelopdysplastic Syndrome
Conditions: Myelodysplastic Syndrome (MDS);   Severe Aplastic Anemia (SAA)
Interventions: Other: Umbilical Cord Blood;   Other: Haploidentical Stem Cells;   Device: Miltenvi CliniMACs CD34 Reagent System

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Study has passed its completion date and status has not been verified in more than two years.