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83 studies found for:    Open Studies | "Amyotrophic Lateral Sclerosis"
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21 Recruiting Neuroinflammation in Amyotrophic Lateral Sclerosis - Mechanisms and Therapeutic Perspectives: a Translational Pilot Study Among ALS Patients
Condition: Amyotrophic Lateral Sclerosis (ALS)
Interventions: Other: ALS Functional rating Scale-revised (ALS FRS-R);   Other: slow vital capacity;   Other: Blood sample;   Other: Cerebrospinal Fluid (CSF) sample
22 Recruiting Oral Nutritional Supplementation in Amyotrophic Lateral Sclerosis (ALS) Patients
Condition: Amyotrophic Lateral Sclerosis (ALS)
Intervention: Dietary Supplement: Oral nutritional supplementation
23 Recruiting Intramuscular Infusion of Autologous Bone Marrow Stem Cells in Patients With Amyotrophic Lateral Sclerosis
Condition: ALS (Amyotrophic Lateral Sclerosis)
Interventions: Biological: MNC (Mononuclear cells);   Other: Saline
24 Recruiting Predict to Prevent Frontotemporal Lobar Degeneration (FDT) and Amyotrophic Lateral Sclerosis (ALS)
Conditions: Frontotemporal Lobar Degeneration;   Amyotrophic Lateral Sclerosis
Intervention: Behavioral: characterization
25 Recruiting Clinical Trial of Ezogabine (Retigabine) in ALS Subjects
Condition: Amyotrophic Lateral Sclerosis
Interventions: Drug: Ezogabine;   Drug: Placebo
26 Recruiting Non-Invasive Measurement of Gastrointestinal (GI) Motility in Patients With Amyotrophic Lateral Sclerosis (ALS)
Condition: Amyotrophic Lateral Sclerosis
Intervention:
27 Recruiting Noninvasive Assessment of Neuronal Damage by MRI Sodium ( 23Na ) in Amyotrophic Lateral Sclerosis
Condition: Amyotrophic Lateral Sclerosis
Intervention: Other: sodium MRI
28 Recruiting Study of Two Intrathecal Doses of Autologous Mesenchymal Stem Cells for Amyotrophic Lateral Sclerosis
Condition: AMYOTROPHIC LATERAL SCLEROSIS
Intervention: Other: Two intrathecal MSC injections
29 Recruiting Chewing Efficiency Measured by a Two Colour Chewing Gum Test in Amyotrophic Lateral Sclerosis (ALS) Patients?
Condition: Amyotrophic Lateral Sclerosis 11
Intervention:
30 Not yet recruiting The Use of Airway Clearance Devices in ALS
Condition: Amyotrophic Lateral Sclerosis
Interventions: Device: High Frequency Chest Compression Device (HFCC);   Device: Cough Assist
31 Recruiting Safety and Biomarker Study of EPI-589 in Subjects With ALS
Condition: Amyotrophic Lateral Sclerosis
Intervention: Drug: EPI-589
32 Recruiting "New Perspectives of Adaptation to NIV in ALS"
Condition: Amyotrophic Lateral Sclerosis (ALS)
Intervention: Other: Adaptation and training to Non Invasive Ventilation (NIV)
33 Recruiting Natural History and Biomarkers of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Caused by the C9ORF72 Gene Mutation
Conditions: Amyotrophic Lateral Sclerosis;   Frontotemporal Lobar Degeneration
Intervention:
34 Not yet recruiting CNS10-NPC-GDNF for the Treatment of ALS
Condition: Amyotrophic Lateral Sclerosis
Intervention: Biological: Stem cell (HPC) implantation
35 Recruiting Amyotrophic Lateral Sclerosis and the Innate Immune System
Conditions: Amyotrophic Lateral Sclerosis;   Neurodegenerative Disease;   Motor Neuron Disease
Intervention:
36 Recruiting Methodology Study of Novel Outcome Measures to Assess Progression of ALS
Condition: Amyotrophic Lateral Sclerosis (ALS)
Intervention:
37 Recruiting A Study to Evaluate the Performance of a Diagnostic Test in ALS
Condition: Amyotrophic Lateral Sclerosis (ALS)
Intervention: Procedure: Lumbar puncture
38 Recruiting Study of miRNA Expression Pattern as Diagnostic and Prognostic Biomarker in Amyotrophic Lateral Sclerosis
Conditions: Amyotrophic Lateral Sclerosis;   ALS
Interventions: Other: Clinical evaluation;   Procedure: Muscular biopsy;   Procedure: Lumbar puncture;   Procedure: Blood sampling;   Other: Neurological assessments;   Procedure: Neuro-muscular biopsy and lumbar puncture;   Procedure: Blood sample;   Device: Cervical spinal cord and brain MRI
39 Recruiting Microglial Activation Role In ALS (MARIA)
Condition: Amyotrophic Lateral Sclerosis
Intervention: Drug: [18F]DPA-714 PET
40 Not yet recruiting Therapy in Amyotrophic Lateral Sclerosis With Memantine at 20 mg BID (TAME)
Conditions: Amyotrophic Lateral Sclerosis;   Frontal Temporal Dementia
Interventions: Drug: Memantine;   Drug: Placebo (for Memantine)

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Study has passed its completion date and status has not been verified in more than two years.