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50 studies found for:    Open Studies | "Adenoviridae Infections"
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Rank Status Study
1 Available Expanded Access Protocol to Provide Brincidofovir for the Treatment of Serious Adenovirus Infection or Disease
Condition: Adenovirus
Intervention: Drug: Brincidofovir
2 Not yet recruiting Most Closely Human Leukocyte Antigen (HLA)-Matched Adenovirus-specific T Lymphocytes (Viralym-A)
Condition: Adenovirus Infection
Intervention: Biological: Viralym-A
3 Recruiting Using Multi-virus Cytotoxic T-cells Following T-Cell Depleted Allogeneic HPCT for Prophylaxis Against Epstein Barr Virus, Adenovirus, And Cytomegalovirus
Conditions: Epstein-Barr Virus Infections;   Adenovirus;   Cytomegalovirus Infections
Intervention: Biological: Cytotoxic T Lymphocytes
4 Not yet recruiting Phase 1 Clinical Trial to Evaluate the Safety and Immunogenicity of an Adenovirus-based Tuberculosis Vaccine Administered by Aerosol
Condition: Tuberculosis
Intervention: Biological: Ad5Ag85A
5 Recruiting Virus-specific ImmunoTherapy Following Allogeneic Stem Cell Transplantation
Conditions: Cytomegalovirus Infection;   Adenovirus Infection
Intervention: Biological: virus-specific T-Cells
6 Recruiting Clinical Trial of Recombinant Adenovirus Type 5 AIDS Vaccine
Condition: Acquired Immunodeficiency Syndrome
Interventions: Biological: Ad5-gag;   Biological: Placebo
7 Recruiting Oncolytic Adenovirus-Mediated Gene Therapy for Lung Cancer
Condition: Non-small Cell Lung Cancer Stage I
Intervention: Biological: Ad5-yCD/mutTKSR39rep-ADP Adenovirus
8 Recruiting Cytotoxic T Cells to Prevent Virus Infections
Conditions: CMV;   EBV;   Adenovirus Infections
Intervention: Drug: Cytotoxic T lymphocytes (CTLs).
9 Recruiting ARMS - Rapidly Generated Multivirus-Specific CTLs for the Prophylaxis And Treatment of EBV, CMV, Adenovirus, HHV6, and BK Virus
Condition: Viral Infection
Intervention: Biological: Multi-virus-specific cytotoxic T lymphocytes
10 Recruiting Combination Adenovirus + Pembrolizumab to Trigger Immune Virus Effects
Conditions: Brain Cancer;   Brain Neoplasm;   Glioma;   Glioblastoma;   Gliosarcoma;   Malignant Brain Tumor;   Neoplasm, Neuroepithelial;   Neuroectodermal Tumors;   Neoplasm by Histologic Type;   Neoplasm, Nerve Tissue;   Nervous System Diseases
Interventions: Biological: DNX-2401;   Biological: pembrolizumab
11 Recruiting Study of Recombinant Adenovirus AdVince in Patients With Neuroendocrine Tumors; Safety and Efficacy
Condition: Neuroendocrine Tumors
Intervention: Drug: AdVince
12 Not yet recruiting Adenovirus Vascular Endothelial Growth Factor D (AdvVEGF-D) Therapy for Treatment of Refractory Angina Pectoris
Conditions: Refractory Angina Pectoris;   Gene Transfer;   Coronary Artery Disease
Interventions: Drug: AdvVEGF-D;   Drug: Control Rx
13 Recruiting MG1 Maraba/MAGE-A3, With and Without Adenovirus Vaccine, With Transgenic MAGE-A3 Insertion in Patients With Incurable MAGE-A3-Expressing Solid Tumours
Condition: Advanced/Metastatic Solid Tumours
Interventions: Biological: MG1MA3;   Biological: AdMA3
14 Not yet recruiting Systemic Chemotherapy Combined With Recombinant Human Adenovirus Type 5 and Endostatin Injections for Treatment Malignant Hydrothorax in NSCLC Patients
Conditions: Malignant Hydrothorax;   Non Small Cell Lung Cancer
Interventions: Drug: Gemcitabine;   Drug: Vinorelbine;   Drug: Paclitaxel;   Drug: Pemetrexed;   Drug: Oncorine;   Drug: Endostar;   Drug: Cisplatin
15 Recruiting A Pilot Study of Sequential ONCOS-102, an Engineered Oncolytic Adenovirus Expressing GMCSF, and Pembrolizumab in Patients With Advanced or Unresectable Melanoma Progressing After Programmed Cell Death Protein 1 (PD1) Blockade
Condition: Advanced or Unresectable Melanoma Progressing After PD1 Blockade
Interventions: Biological: ONCOS-102;   Drug: Cyclophosphamide;   Drug: Pembrolizumab
16 Recruiting A Randomised Phase II Open-label Study With a Phase Ib Safety lead-in Cohort of ONCOS-102, an Immune-priming GM-CSF Coding Oncolytic Adenovirus, and Pemetrexed/Cisplatin in Patients With Unresectable Malignant Pleural Mesothelioma
Condition: To Determine Safety, Tolerability and Efficacy of ONCOS-102 in Combination With Chemotherapy
Interventions: Biological: ONCOS-102;   Drug: Pemetrexed/cisplatin;   Drug: Cyclophosphamide
17 Recruiting Clinical Trial Phase I for Theragene in Combination With Chemotherapy for the Locally Advanced Pancreatic Cancer
Condition: Pancreatic Cancer
Intervention: Biological: Theragene®,Ad5-yCD/mutTKSR39rep-ADP
18 Recruiting Partially HLA-matched Third Party Antigen Specific T-cells for Infection Post-stem Cell or Solid Organ Transplantation
Conditions: CMV Infection;   EBV;   Adenovirus
Intervention: Biological: Virus specific CTLs
19 Recruiting Allogeneic Multivirus - Directed Cytotoxic T Lymphocytes (CTL)
Conditions: EBV;   CMV;   Adenovirus
Interventions: Drug: CTL for CMV seropositive donors;   Drug: CTL for CMV naïve donors
20 Recruiting Phase 1 Trial of Interleukin 12 Gene Therapy for Locally Recurrent Prostate Cancer
Condition: Prostate Cancer
Intervention: Biological: Ad5-yCD/mutTKSR39rep-hIL12

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Study has passed its completion date and status has not been verified in more than two years.