78389 studies found for:    "Physiological Effects of Drugs"
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Rank Status Study
1 Completed The Effect of Caffeine in Elderly Citizen Following Eight Hour Abstinence From Caffeine Containing Drinks & Foods
Conditions: Healthy;   Elderly
Intervention: Drug: Caffeine
2 Completed University of Texas H.S.C. San Antonio Pioglitazone in Non-Alcoholic Steatohepatitis Trial (UTHSCSA NASH Trial)
Conditions: Nonalcoholic Steatohepatitis;   Nonalcoholic Fatty Liver Disease;   Type 2 Diabetes Mellitus
Interventions: Drug: Pioglitazone;   Drug: Placebo
3 Completed Effect of Pioglitazone Versus Metformin on Bone Health in Postmenopausal Women With Type 2 Diabetes
Conditions: Diabetes Mellitus;   Diabetes Mellitus, Type 2;   Glucose Metabolism Disorders
Interventions: Drug: Pioglitazone;   Drug: Metformin
4 Active, not recruiting Six Month Treatment of Growth Hormone Releasing Hormone (GHRH) in the Elderly
Condition: Elderly
Intervention: Drug: GHRH
5 Recruiting Prevention of Bone Loss After Acute SCI by Zoledronic Acid
Conditions: Spinal Cord Injury;   Acute Spinal Cord Injury;   Bone Loss;   Osteoporosis
Interventions: Drug: Zoledronic acid;   Drug: Placebo
6 Active, not recruiting 12 Month Extension Study of the Effect of Teriparatide on Bone in People With Chronic Spinal Cord Injury (SCI)
Conditions: Spinal Cord Injury;   Bone Loss;   Osteoporosis
Interventions: Drug: Teriparatide;   Device: Vibration
7 Recruiting ADC-1013 First-in-Human Study
Conditions: Neoplasms;   Solid Tumors
Intervention: Biological: ADC-1013
8 Active, not recruiting Immunogenicity, Safety, and Tolerability of a Plant-Derived Quadrivalent VLP Influenza Vaccine in Elderly Adults
Conditions: Virus Diseases;   RNA Virus Infections;   Respiratory Tract Diseases;   Respiratory Tract Infections
Interventions: Biological: 30 µg/strain of Quadrivalent VLP Vaccine;   Biological: 60 µg/strain of Quadrivalent VLP Vaccine;   Biological: FluLaval® Tetra (15 µg/strain);   Biological: Fluzone® High-Dose (60 µg/strain)
9 Active, not recruiting Immunogenicity of a Quadrivalent Virus-Like Particles (VLP) Influenza Vaccine in Healthy Adults
Conditions: Virus Diseases;   RNA Virus Infections;   Respiratory Tract Diseases;   Respiratory Tract Infections
Interventions: Biological: 15 µg/strain of Quadrivalent VLP Vaccine;   Biological: 30 µg/strain of Quadrivalent VLP Vaccine;   Biological: 15 µg/strain of the licensed quadrivalent vaccine
10 Active, not recruiting Immunogenicity, Safety and Tolerability of a Plant-Derived Seasonal Virus-Like-Particle Quadrivalent Influenza Vaccine in Adults
Conditions: Virus Diseases;   RNA Virus Infections;   Respiratory Tract Diseases;   Respiratory Tract Infections
Interventions: Biological: Low dose of quadrivalent VLP vaccine;   Biological: Medium dose of quadrivalent VLP vaccine;   Biological: High dose of quadrivalent VLP vaccine;   Biological: Placebo
11 Completed Safety, Tolerability and Immunogenicity of a Plant-made Seasonal Quadrivalent VLP Influenza Vaccine in Adults
Conditions: Virus Diseases;   RNA Virus Infections;   Respiratory Tract Diseases;   Respiratory Tract Infections
Interventions: Biological: Low dose of quadrivalent VLP vaccine;   Biological: Medium dose of quadrivalent VLP vaccine;   Biological: High dose of quadrivalent VLP vaccine;   Biological: Placebo
12 Recruiting PET/CT Imaging Study of the Safety and Diagnostic Performance of [68Ga]RM2 in Patients With Primary Prostate Cancer
Condition: Prostate Cancer
Interventions: Drug: [68Ga]RM2;   Procedure: PET/CT
13 Completed
Has Results
A Study to Assess the Safety, Tolerability and Glucose-Lowering Efficacy of MK-0893 in Participants With Type 2 Diabetes Mellitus (MK-0893-005)
Condition: Type 2 Diabetes Mellitus
Interventions: Drug: MK-0893;   Drug: Metformin;   Drug: Placebo
14 Active, not recruiting A Study of Brentuximab Vedotin in Patients With Relapsed or Refractory Hodgkin Lymphoma
Condition: Hodgkin Lymphoma
Intervention: Drug: Brentuximab vedotin
15 Completed
Has Results
A Phase 2 Study to Evaluate Analgesic Effect of IV CR845 For Pain Following Bunionectomy Surgery
Condition: Acute Pain
Interventions: Drug: CR845;   Drug: Placebo
16 Completed
Has Results
Study to Evaluate Analgesic Effect of IV Administration of Kappa Agonist CR845 For Hysterectomy Surgery
Condition: Postoperative Pain
Interventions: Drug: CR845;   Drug: Placebo
17 Unknown  The Use of Anti-CD4 mAb-Fragment for Imaging of Local Inflammation in Patients With Carotid Artery Stenosis
Condition: Carotid Stenosis
Intervention: Radiation: EP 1645/Solution For Injection, 99mTC
18 Completed
Has Results
Study to Evaluate Analgesic Effect of Intravenous Administration of Kappa Agonist CR845 After Hysterectomy Surgery
Condition: Acute Pain
Interventions: Drug: CR845;   Drug: Placebo
19 Completed
Has Results
Study of Dapagliflozin in Combination With Metformin XR to Initiate the Treatment of Type 2 Diabetes
Condition: Type 2 Diabetes Mellitus
Interventions: Drug: Dapagliflozin;   Drug: Metformin XR;   Drug: dapagliflozin matching Placebo;   Drug: metformin HCl Modified Release matching Placebo
20 Completed
Has Results
A Phase III Study of BMS-512148 (Dapagliflozin) in Patients With Type 2 Diabetes Who Are Not Well Controlled on Metformin Alone
Condition: Type 2 Diabetes
Interventions: Drug: Dapagliflozin;   Drug: Placebo;   Drug: Metformin

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Study has passed its completion date and status has not been verified in more than two years.