75417 studies found for:    "Physiological Effects of Drugs"
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Rank Status Study
1 Recruiting Immunogenicity, Safety, and Tolerability of a Plant-Derived Quadrivalent VLP Influenza Vaccine in Elderly Adults
Conditions: Virus Diseases;   RNA Virus Infections;   Respiratory Tract Diseases;   Respiratory Tract Infections
Interventions: Biological: 30 µg/strain of Quadrivalent VLP Vaccine;   Biological: 60 µg/strain of Quadrivalent VLP Vaccine;   Biological: FluLaval® Tetra (15 µg/strain);   Biological: Fluzone® High-Dose (60 µg/strain)
2 Recruiting Immunogenicity of a Quadrivalent Virus-Like Particles (VLP) Influenza Vaccine in Healthy Adults
Conditions: Virus Diseases;   RNA Virus Infections;   Respiratory Tract Diseases;   Respiratory Tract Infections
Interventions: Biological: 15 µg/strain of Quadrivalent VLP Vaccine;   Biological: 30 µg/strain of Quadrivalent VLP Vaccine;   Biological: 15 µg/strain of the licensed quadrivalent vaccine
3 Not yet recruiting CoQ10 in Gulf War Illness
Conditions: Gulf War Illness;   Chronic Fatigue;   Ubiquinol;   Coenzyme Q10
Interventions: Drug: Ubiquinol;   Drug: Placebo
4 Recruiting Pilot Study: Echocardiographic and Hemodynamic Effects of Esmolol in Septic Shock Patients
Condition: Shock, Septic
Intervention: Drug: Esmolol
5 Recruiting Cognitive Recovery After Electroconvulsive Therapy and General Anesthesia
Conditions: Depression;   Delirium;   Seizures;   Cognitive Disorders
Interventions: Drug: Ketamine;   Procedure: Electroconvulsive Therapy
6 Recruiting Rate Control in Atrial Fibrillation II
Conditions: Atrial Fibrillation;   Permanent Atrial Fibrillation
Interventions: Drug: Metoprolol;   Drug: Diltiazem
7 Recruiting Pharmacologically-augmented Cognitive Therapies (PACTs) for Schizophrenia.
Condition: Schizophrenia
Interventions: Drug: Dextroamphetamine;   Drug: Placebo
8 Recruiting Ketamine Infusions for PTSD and Treatment-Resistant Depression
Conditions: Depressive Disorder, Treatment-Resistant;   Stress Disorders, Post-Traumatic
Intervention: Drug: Ketamine
9 Recruiting Intrathecal Rituximab in Progressive Multiple Sclerosis
Conditions: Multiple Sclerosis, Chronic Progressive;   Nervous System Diseases
Interventions: Drug: Rituximab IT;   Drug: methylprednisolone IV;   Drug: Rituximab IV
10 Recruiting PET/CT Imaging Study of the Safety and Diagnostic Performance of [68Ga]RM2 in Patients With Primary Prostate Cancer
Condition: Prostate Cancer
Interventions: Drug: [68Ga]RM2;   Procedure: PET/CT
11 Recruiting Extended-release Naltrexone and Care Management for Alcohol Dependent Frequent Emergency Department Users
Conditions: Alcohol Dependence;   Alcohol Use Disorder
Intervention: Drug: XR-NTX+CM (Extended-Release Naltrexone plus Care Management)
12 Enrolling by invitation Food Intake and Gut Hormones in Patients Who Have Undergone Upper Gastrointestinal Surgery for Cancer
Conditions: Esophageal Neoplasms;   Stomach Neoplasms;   Weight Loss;   Malnutrition
Interventions: Drug: Octreotide;   Drug: Placebo
13 Recruiting ADC-1013 First-in-Human Study
Conditions: Neoplasms;   Solid Tumors
Intervention: Biological: ADC-1013
14 Active, not recruiting Combination Chemotherapy or 90-Yttrium Ibritumomab Tiuxetan and Combination Chemotherapy Before Stem Cell Transplant in Treating Patients With Relapsed Diffuse Large B-cell Non-Hodgkin Lymphoma
Conditions: Recurrent Diffuse Large B-Cell Lymphoma;   Refractory Diffuse Large B-Cell Lymphoma
Interventions: Radiation: Yttrium Y 90 Ibritumomab tiuxetan;   Drug: Carmustine;   Drug: Etoposide;   Drug: Cytarabine;   Drug: Melphalan;   Procedure: Autologous Hematopoietic Stem Cell Transplantation;   Biological: Rituximab;   Procedure: Peripheral Blood Stem Cell Transplantation;   Other: Laboratory Biomarker Analysis
15 Recruiting The Effect of Uric Acid Lowering in Type 1 Diabetes
Condition: Type 1 Diabetes Mellitus
Intervention: Drug: Febuxostat
16 Recruiting Prevention of Bone Loss After Acute SCI by Zoledronic Acid
Conditions: Spinal Cord Injury;   Acute Spinal Cord Injury;   Bone Loss;   Osteoporosis
Interventions: Drug: Zoledronic acid;   Drug: Placebo
17 Recruiting Intra-Peritoneal Local Anaesthesia After Cytoreductive Surgery
Condition: Pain
Interventions: Drug: Ropivacaine;   Drug: Saline
18 Recruiting Perimenopausal Effects of Estradiol on Reward Responsiveness
Condition: Perimenopausal Depression
Interventions: Drug: Estradiol;   Drug: Progesterone
19 Active, not recruiting Immunogenicity, Safety and Tolerability of a Plant-Derived Seasonal VLP Quadrivalent Influenza Vaccine in the Elderly Population
Conditions: Virus Diseases;   RNA Virus Infections;   Respiratory Tract Diseases;   Respiratory Tract Infections
Interventions: Biological: Non-adjuvanted low dose of quadrivalent VLP vaccine;   Biological: Non-adjuvanted medium dose of quadrivalent VLP vaccine;   Biological: Non-adjuvanted high dose of quadrivalent VLP vaccine;   Biological: Adjuvanted low dose of quadrivalent VLP vaccine;   Biological: Adjuvanted high dose of quadrivalent VLP vaccine;   Biological: Placebo
20 Active, not recruiting Immunogenicity, Safety and Tolerability of a Plant-Derived Seasonal Virus-Like-Particle Quadrivalent Influenza Vaccine in Adults
Conditions: Virus Diseases;   RNA Virus Infections;   Respiratory Tract Diseases;   Respiratory Tract Infections
Interventions: Biological: Low dose of quadrivalent VLP vaccine;   Biological: Medium dose of quadrivalent VLP vaccine;   Biological: High dose of quadrivalent VLP vaccine;   Biological: Placebo

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Indicates status has not been verified in more than two years