53797 studies found for:    "Physiological Effects of Drugs"
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1 Active, not recruiting An Open Label Study of Postmenopausal Women With Oestrogen Receptor Positive Locally Advanced or Metastatic Breast Cancer Treated With Everolimus (RAD001) With Exemestane, With Exploratory Epigenetic Marker Analysis
Condition: Oestrogen Receptor Positive Advanced Breast Cancer
Interventions: Drug: RAD001;   Drug: Exemestane
2 Completed Caffeine for Motor Manifestations of Parkinson's Disease
Condition: Parkinson's Disease
Intervention: Drug: Caffeine alkaloid
3 Completed Effect of 10mg Domperidone on Gastric Emptying of a High-fat Meal and Appetite Sensations in Healthy Adults
Condition: Diabetes Mellitus
Interventions: Drug: Domperidone 10mg;   Drug: Placebo
4 Recruiting Prevention of Bone Loss After Acute SCI by Zoledronic Acid
Conditions: Spinal Cord Injury;   Acute Spinal Cord Injury;   Bone Loss;   Osteoporosis
Interventions: Drug: Zoledronic acid;   Drug: Placebo
5 Unknown  Alcohol and Atherosclerosis Pilot Study
Condition: Atherosclerosis
Interventions: Other: Ethanol-free beverage;   Other: Ethanol
6 Completed University of Texas H.S.C. San Antonio Pioglitazone in Non-Alcoholic Steatohepatitis Trial (UTHSCSA NASH Trial)
Conditions: Nonalcoholic Steatohepatitis;   Nonalcoholic Fatty Liver Disease;   Type 2 Diabetes Mellitus
Interventions: Drug: Pioglitazone;   Drug: Placebo
7 Terminated Research Study of IV Vitamin C in Combination With Irinotecan vs Irinotecan Alone for Advanced Colorectal CA
Condition: Stage IV Colorectal Cancer
Intervention: Drug: Vitamin C
8 Completed Antiplatelet Effects of Ticagrelor Versus Clopidogrel in American Indian Patients
Condition: Coronary Artery Disease
Interventions: Drug: Ticagrelor;   Drug: Clopidogrel
9 Completed Efficacy and Safety of Budesonide Foam for Patients With Active Mild to Moderate Ulcerative Proctitis or Proctosigmoiditis
Conditions: Proctitis;   Proctosigmoiditis
Interventions: Drug: Budesonide;   Drug: Placebo
10 Terminated Predictive Biomarkers of Response to Sunitinib in the Treatment of Poorly-differentiated NEURO-Endocrine Tumors
Conditions: Neuroendocrine Tumors;   Pancreatic Neoplasms;   Advanced Disease;   Sunitinib
Intervention: Drug: Sutent
11 Recruiting The Effect of Loop Diuretics on Severity and Outcome of Acute Kidney Injury
Condition: Acute Kidney Failure
Intervention: Drug: Furosemide
12 Completed Effect of Pioglitazone Versus Metformin on Bone Health in Postmenopausal Women With Type 2 Diabetes
Conditions: Diabetes Mellitus;   Diabetes Mellitus, Type 2;   Glucose Metabolism Disorders
Interventions: Drug: Pioglitazone;   Drug: Metformin
13 Completed Study to Evaluate the Safety and Efficacy of the Addition of MK-3102 Compared With the Addition of Sitagliptin in Subjects With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin (MK-3102-026)
Condition: Type 2 Diabetes
Interventions: Drug: MK-3102;   Drug: Sitagliptin;   Drug: Placebo to MK-3102;   Drug: Placebo to Sitagliptin;   Drug: Open-label Metformin;   Drug: Open-label Glimepiride
14 Active, not recruiting Safety and Efficacy of Levamisole Combined With Cyclosporine A in Patients With Classic Paroxysmal Nocturnal Hemoglobinuria
Conditions: Paroxysmal Nocturnal Hemoglobinuria;   Hemoglobinuria;   Hemoglobinuria, Paroxysmal;   Proteinuria;   Urination Disorders;   Thrombosis;   Bone Marrow Failure;   Aplastic Anemia,;   Anemia, Hemolytic
Interventions: Drug: Levamisole+cyclosporin A+Glucocorticoids;   Drug: cyclosporin A+Glucocorticoids;   Drug: Glucocorticoids
15 Active, not recruiting 12 Month Extension Study of the Effect of Teriparatide on Bone in People With Chronic Spinal Cord Injury (SCI)
Conditions: Spinal Cord Injury;   Bone Loss;   Osteoporosis
Interventions: Drug: Teriparatide;   Device: Vibration
16 Completed Effect of Magnesium on the Recovery Time of Neuromuscular Blockade With Sugammadex
Condition: Neuromuscular Blockade
Interventions: Drug: Magnesium Sulfate;   Drug: Saline
17 Unknown  Oxytocin and Tibolone Adjuncts in Treatment Resistant Depression - A Pilot Study
Conditions: Depression;   Major Depressive Disorder
Interventions: Drug: Oxytocin;   Drug: Oxytocin and Tibolone;   Drug: Placebo
18 Unknown  Effects of Alogliptin on Pancreatic Beta Cell Function
Condition: Diabetes Mellitus, Type 2
Interventions: Drug: Alogliptin;   Drug: Metformin 750 mg
19 Completed Study in Infants With Infantile Hemangioma to Compare Propranolol Gel to Placebo
Condition: Infantile Hemangioma
Interventions: Drug: propranolol gel;   Drug: Placebo
20 Completed The Safety and Tolerability of Budesonide Foam in Subjects With Active Ulcerative Proctitis or Proctosigmoiditis
Conditions: Proctitis;   Proctosigmoiditis
Intervention: Drug: Budesonide Foam

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Indicates status has not been verified in more than two years