55261 studies found for:    "Physiological Effects of Drugs"
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Rank Status Study
1 Not yet recruiting Extended-release Naltrexone and Care Management for Alcohol Dependent Frequent Emergency Department Users
Conditions: Alcohol Dependence;   Alcohol Use Disorder
Intervention: Drug: XR-NTX+CM (Extended-Release Naltrexone plus Care Management)
2 Recruiting Combination Chemotherapy or 90-Yttrium Ibritumomab Tiuxetan and Combination Chemotherapy Before Stem Cell Transplant in Treating Patients With Relapsed Diffuse Large B-cell Non-Hodgkin Lymphoma
Conditions: Recurrent Diffuse Large B-Cell Lymphoma;   Refractory Diffuse Large B-Cell Lymphoma
Interventions: Radiation: Yttrium Y 90 Ibritumomab tiuxetan;   Drug: Carmustine;   Drug: Etoposide;   Drug: Cytarabine;   Drug: Melphalan;   Procedure: Autologous Hematopoietic Stem Cell Transplantation;   Biological: Rituximab;   Procedure: Peripheral Blood Stem Cell Transplantation;   Other: Laboratory Biomarker Analysis
3 Recruiting The Effect of Uric Acid Lowering in Type 1 Diabetes
Condition: Type 1 Diabetes Mellitus
Intervention: Drug: Febuxostat
4 Recruiting Prevention of Bone Loss After Acute SCI by Zoledronic Acid
Conditions: Spinal Cord Injury;   Acute Spinal Cord Injury;   Bone Loss;   Osteoporosis
Interventions: Drug: Zoledronic acid;   Drug: Placebo
5 Recruiting Intra-Peritoneal Local Anaesthesia After Cytoreductive Surgery
Condition: Pain
Interventions: Drug: Ropivacaine;   Drug: Saline
6 Not yet recruiting Perimenopausal Effects of Estradiol on Reward Responsiveness
Condition: Perimenopausal Depression
Interventions: Drug: Estradiol;   Drug: Progesterone
7 Recruiting Walking Effect of Long Term Ticagrelor in Subjects With PAD Who Have Undergone EVR
Condition: Peripheral Artery Disease (PAD)
Interventions: Drug: Ticagrelor;   Drug: Comparator
8 Completed Oral Testosterone for the Treatment of Hypogonadism in Males
Condition: Hypogonadism
Intervention: Drug: TSX-002
9 Enrolling by invitation Effect of Alendronate on Bone in People With Chronic Spinal Cord Injury Previously Treated With Teriparatide
Conditions: Spinal Cord Injury;   Bone Loss;   Osteoporosis
Interventions: Drug: Alendronate;   Dietary Supplement: Calcium;   Dietary Supplement: Vitamin D
10 Recruiting Resveratrol and First-degree Relatives of Type 2 Diabetic Patients
Condition: Pre-diabetes
Interventions: Dietary Supplement: placebo;   Dietary Supplement: resveratrol
11 Recruiting Vascular Function and Uterine Fibroids
Condition: Leiomyoma
Interventions: Device: Brachial artery catheter;   Drug: Acetylcholine;   Drug: Nitroprusside;   Drug: Norepinephrine;   Drug: Nitroprusside and phenylephrine
12 Completed Liraglutide as add-on to Insulin in Type 1 Diabetes
Conditions: Diabetes;   Diabetes Mellitus, Type 1
Interventions: Drug: Liraglutide;   Drug: Placebo
13 Completed Safety and Efficacy of Oral LPCN 1021 in Men With Low Testosterone or Hypogonadism
Condition: Male Hypogonadism
Interventions: Drug: Oral testosterone undecanoate, LPCN 1021;   Drug: Topical testosterone gel 1.62 %
14 Completed
Has Results
Open-label, Single-arm Study to Assess the Pharmacokinetics, Safety, and Tolerability of a Single Subcutaneous Dose of Icatibant in Healthy Japanese Volunteers
Condition: Hereditary Angioedema (HAE)
Intervention: Drug: Icatibant (30 mg)
15 Active, not recruiting 12 Month Extension Study of the Effect of Teriparatide on Bone in People With Chronic Spinal Cord Injury (SCI)
Conditions: Spinal Cord Injury;   Bone Loss;   Osteoporosis
Interventions: Drug: Teriparatide;   Device: Vibration
16 Active, not recruiting Safety, Tolerability and Immunogenicity of a Plant-made H7 Virus-like Particle (VLP) Influenza Vaccine in Adults.
Conditions: Virus Diseases;   RNA Virus Infections;   Respiratory Tract Diseases;   Respiratory Tract Infections
Interventions: Biological: Low dose of H7 VLP vaccine + Alhydrogel;   Biological: Med dose of H7 VLP vaccine + Alhydrogel;   Biological: High dose of H7 VLP vaccine + Alhydrogel;   Biological: High dose of H7 VLP vaccine;   Biological: Placebo
17 Completed A Study of MK-0893 on Glucagon-Induced Glycemic Excursion in Healthy Male Participants Following Intravenous Administration of Glucagon, Sandostatine® and Insulin (MK-0893-002)
Condition: Type 2 Diabetes Mellitus
Interventions: Drug: MK-0893 10 mg;   Drug: MK-0893 40 mg;   Drug: MK-0893 200 mg;   Drug: MK-0893 1000 mg;   Drug: Placebo;   Biological: Sandostatine®;   Biological: Insulin;   Biological: Glucagon
18 Recruiting Phase I Study of a Dendritic Cell Vaccine for Patients With Either Newly Diagnosed or Recurrent Glioblastoma
Conditions: Glioblastoma;   Glioblastoma Multiforme;   Glioma;   Astrocytoma;   Brain Tumor
Interventions: Biological: Dendritic cell vaccination, in addition to standard temozolomide chemotherapy and involved field radiation therapy;   Biological: Dendritic cell vaccination, with optional bevacizumab treatment for patients previously treated with bevacizumab
19 Completed
Has Results
A Study to Assess the Safety, Tolerability and Glucose-Lowering Efficacy of MK-0893 in Participants With Type 2 Diabetes Mellitus (MK-0893-005)
Condition: Type 2 Diabetes Mellitus
Interventions: Drug: MK-0893;   Drug: Metformin;   Drug: Placebo
20 Completed Efficacy and Safety Study to Evaluate Two Doses of Oral DMI-5207 in Adult Subjects With Diabetic Macular Edema
Condition: Diabetic Macular Edema
Intervention: Drug: Danazol

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Indicates status has not been verified in more than two years