80166 studies found for:    "Pharmacologic Actions"
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Rank Status Study
1 Completed
Has Results
Prasugrel/Clopidogrel Maintenance Dose Washout Study
Condition: Coronary Artery Disease
Interventions: Drug: prasugrel;   Drug: clopidogrel
2 Terminated Study of Sunitinib in Patients With Advanced/Inoperable Fibrolamellar Carcinoma
Conditions: Hepatocellular Carcinoma;   Fibrolamellar Hepatocellular Carcinoma
Intervention: Drug: Sutent
3 Recruiting Oral Testosterone for the Treatment of Hypogonadism in Males
Condition: Hypogonadism
Intervention: Drug: TSX-002
4 Completed Study to Evaluate the Safety and Efficacy of the Addition of MK-3102 Compared With the Addition of Sitagliptin in Subjects With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin (MK-3102-026)
Condition: Type 2 Diabetes
Interventions: Drug: MK-3102;   Drug: Sitagliptin;   Drug: Placebo to MK-3102;   Drug: Placebo to Sitagliptin;   Drug: Open-label Metformin;   Drug: Open-label Glimepiride
5 Unknown  Influence of Atorvastatin on Psoriasis Severity and Endothelial Function
Condition: Psoriasis
Interventions: Drug: Atorvastatin;   Drug: Atorvastatin placebo
6 Completed
Has Results
Deep Vein Thrombosis Treatment With the Oral Direct Factor Xa Inhibitor Rivaroxaban in Patients Using a Strong CYP 3A4 Inducer
Conditions: Venous Thrombosis;   Deep Vein Thrombosis
Intervention: Drug: Rivaroxaban (Xarelto, BAY59-7939)
7 Unknown  Effects of Alogliptin on Pancreatic Beta Cell Function
Condition: Diabetes Mellitus, Type 2
Interventions: Drug: Alogliptin;   Drug: Metformin 750 mg
8 Terminated
Has Results
Phase I/II Study of KRN330 Plus Irinotecan in Patients With Metastatic Colorectal Cancer
Condition: Colorectal Cancer
Interventions: Biological: KRN330;   Drug: Irinotecan
9 Unknown  Levonorgestrel-Intrauterine System (LNG-IUS) Insertion in the Postpartum Period
Condition: Contraception
Intervention: Device: Levonorgestrel Intrauterine System (LNG-IUS: Mirena, Bayer)
10 Terminated Predictive Biomarkers of Response to Sunitinib in the Treatment of Poorly-differentiated NEURO-Endocrine Tumors
Conditions: Neuroendocrine Tumors;   Pancreatic Neoplasms;   Advanced Disease;   Sunitinib
Intervention: Drug: Sutent
11 Completed University of Texas H.S.C. San Antonio Pioglitazone in Non-Alcoholic Steatohepatitis Trial (UTHSCSA NASH Trial)
Conditions: Nonalcoholic Steatohepatitis;   Nonalcoholic Fatty Liver Disease;   Type 2 Diabetes Mellitus
Interventions: Drug: Pioglitazone;   Drug: Placebo
12 Recruiting High-dose Vitamin D Supplementation for ADT-induced Side Effects
Conditions: Prostatic Neoplasms;   Bone Mineral Density Quantitative Trait Locus 3
Interventions: Dietary Supplement: vitamin D;   Dietary Supplement: Placebo
13 Terminated Clinical Trial of High-dose Vitamin C for Advanced Pancreatic Cancer
Conditions: Pancreatic Neoplasms;   Pancreatic Cancer
Intervention: Drug: Gemcitabine with escalating ascorbic acid
14 Completed
Has Results
Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed-Dose Combination ± Ribavirin for the Treatment of HCV (ION-3)
Condition: Chronic Hepatitis C Virus
Interventions: Drug: LDV/SOF;   Drug: RBV
15 Recruiting A Study of Intravenous Zanamivir Versus Oral Oseltamivir in Adults and Adolescents Hospitalized With Influenza
Condition: Influenza, Human
Interventions: Drug: 300mg intravenous (IV) zanamivir and oral oseltamivir placebo;   Drug: 600mg intravenous (IV) zanamivir and oral oseltamivir placebo;   Drug: 75mg oral oseltamivir and intravenous zanamivir placebo
16 Terminated Laboratory-Treated Autologous Lymphocytes, Aldesleukin, and Sargramostim (GM-CSF) in Treating Advanced Solid Tumors
Conditions: Neoplasms;   Tumors;   Solid Tumors;   Metastatic Cancer
Intervention: Biological: EGFRBi-armed autologous activated T cells
17 Completed Zonisamide for the Treatment of Obstructive Sleep Apnea in Overweight/Obese Patients
Conditions: Sleep Apnea;   Obstructive Sleep Apnea;   Obesity
Interventions: Drug: Zonisamide;   Drug: Placebo;   Device: nCPAP
18 Completed A Phase 1 Dose-Escalation Study in Advanced Solid Tumors, Lymphomas or Multiple Myeloma
Conditions: Malignant Solid Tumor;   Lymphomas;   Multiple Myeloma
Interventions: Biological: AV-299;   Biological: AV-299 + erlotinib
19 Active, not recruiting A Study of Brentuximab Vedotin in Patients With Relapsed or Refractory Hodgkin Lymphoma
Condition: Hodgkin Lymphoma
Intervention: Drug: Brentuximab vedotin
20 Completed A Safety Study Utilizing Yondelis and Doxorubicin in Patients With a Type of Cancer Called Soft Tissue Sarcoma
Conditions: Soft Tissue Sarcoma;   Sarcoma;   Neoplasms, Connective and Soft Tissue;   Neoplasms by Histologic Type;   Neoplasms
Interventions: Drug: Doxorubicin;   Drug: Trabectedin;   Drug: Dexamethasone

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Indicates status has not been verified in more than two years