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145 studies found for:    "Pharmacologic Actions"
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Rank Status Study
1 Recruiting A Phase I Study of TAS-102 in Patients With Advanced Solid Tumors With Renal Impairment
Condition: Advanced Solid Tumors
Intervention: Drug: TAS-102
2 Completed
Has Results
Prasugrel/Clopidogrel Maintenance Dose Washout Study
Condition: Coronary Artery Disease
Interventions: Drug: prasugrel;   Drug: clopidogrel
3 Not yet recruiting CoQ10 in Gulf War Illness
Conditions: Gulf War Illness;   Chronic Fatigue;   Ubiquinol;   Coenzyme Q10
Interventions: Drug: Ubiquinol;   Drug: Placebo
4 Recruiting Pilot Study: Echocardiographic and Hemodynamic Effects of Esmolol in Septic Shock Patients
Condition: Shock, Septic
Intervention: Drug: Esmolol
5 Recruiting Hydroxychloroquine Sulfate Alleviates Persistent Proteinuria in IgA Nephropathy
Condition: Primary IgA Nephropathy
Interventions: Drug: Hydroxychloroquine Sulfate;   Drug: Valsartan
6 Recruiting Cognitive Recovery After Electroconvulsive Therapy and General Anesthesia
Conditions: Depression;   Delirium;   Seizures;   Cognitive Disorders
Interventions: Drug: Ketamine;   Procedure: Electroconvulsive Therapy
7 Recruiting Safety and Pharmacokinetics of UV-4B Solution Administered Orally as Multiple Ascending Doses to Healthy Subjects
Condition: Viral Infection
Interventions: Drug: UV-4B 30 mg oral solution;   Drug: UV-4B 75 mg oral solution;   Drug: UV-4B 150 mg oral solution;   Drug: UV-4B X mg (dose to be determined) oral solution;   Drug: UV-4B Y mg (dose to be determined) oral solution;   Drug: Placebo
8 Recruiting Pharmacologically-augmented Cognitive Therapies (PACTs) for Schizophrenia.
Condition: Schizophrenia
Interventions: Drug: Dextroamphetamine;   Drug: Placebo
9 Recruiting Efficacy of Memantine add-on in the Treatment of Bipolar Disorder (Type I) Nonresponders or Partial Responders Patients
Condition: Bipolar Disorder
Interventions: Drug: Memantine;   Drug: Placebo
10 Recruiting Ketamine Infusions for PTSD and Treatment-Resistant Depression
Conditions: Depressive Disorder, Treatment-Resistant;   Stress Disorders, Post-Traumatic
Intervention: Drug: Ketamine
11 Not yet recruiting A Pilot Study of MONOtherapy of DOlutegravir in HIV-1 Virologically Suppressed Patients
Conditions: Human Immunodeficiency Virus;   Dolutegravir;   Monotherapy;   Treatment Efficacy
Intervention: Drug: Dolutegravir
12 Recruiting Safety Study of Zinc Finger Nuclease CCR5-modified Hematopoietic Stem/Progenitor Cells in HIV-1 Infected Patients
Condition: HIV
Intervention: Genetic: SB-728mR-HSPC Infusion 3 days following busulfan conditioning
13 Recruiting PET/CT Imaging Study of the Safety and Diagnostic Performance of [68Ga]RM2 in Patients With Primary Prostate Cancer
Condition: Prostate Cancer
Interventions: Drug: [68Ga]RM2;   Procedure: PET/CT
14 Recruiting An Observational Study to Evaluate the Incidence of and Risk Factors for Vascular Occlusive Events Associated With Iclusig®
Condition: Myeloid Leukemia, Chronic, Chronic-Phase
Intervention:
15 Recruiting Extended-release Naltrexone and Care Management for Alcohol Dependent Frequent Emergency Department Users
Conditions: Alcohol Dependence;   Alcohol Use Disorder
Intervention: Drug: XR-NTX+CM (Extended-Release Naltrexone plus Care Management)
16 Recruiting The Effects of Psilocybin-Facilitated Experience on the Psychology and Effectiveness of Religious Professionals
Condition: The Effects of Psilocybin-Facilitated Experience on the Psychology and Effectiveness of Professional Leaders in Religion
Intervention: Drug: Psilocybin
17 Recruiting A Prospective, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of a Single Injection of Rexlemestrocel-L Alone or Combined With Hyaluronic Acid (HA) in Subjects With Chronic Low Back Pain
Condition: Degenerative Disc Disease
Interventions: Drug: rexlemestrocel-L;   Drug: rexlemestrocel-L + HA;   Drug: Placebo
18 Enrolling by invitation Food Intake and Gut Hormones in Patients Who Have Undergone Upper Gastrointestinal Surgery for Cancer
Conditions: Esophageal Neoplasms;   Stomach Neoplasms;   Weight Loss;   Malnutrition
Interventions: Drug: Octreotide;   Drug: Placebo
19 Active, not recruiting Combination Chemotherapy or 90-Yttrium Ibritumomab Tiuxetan and Combination Chemotherapy Before Stem Cell Transplant in Treating Patients With Relapsed Diffuse Large B-cell Non-Hodgkin Lymphoma
Conditions: Recurrent Diffuse Large B-Cell Lymphoma;   Refractory Diffuse Large B-Cell Lymphoma
Interventions: Radiation: Yttrium Y 90 Ibritumomab tiuxetan;   Drug: Carmustine;   Drug: Etoposide;   Drug: Cytarabine;   Drug: Melphalan;   Procedure: Autologous Hematopoietic Stem Cell Transplantation;   Biological: Rituximab;   Procedure: Peripheral Blood Stem Cell Transplantation;   Other: Laboratory Biomarker Analysis
20 Recruiting The Effect of Uric Acid Lowering in Type 1 Diabetes
Condition: Type 1 Diabetes Mellitus
Intervention: Drug: Febuxostat

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