786 studies found for:    "Narcotic Antagonists"
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Rank Status Study
1 Completed Prevention of Stimulant-Induced Euphoria With an Opioid Receptor Antagonist
Conditions: ADHD;   Stimulant-Induced Euphoria
Interventions: Drug: SODAS MPH;   Drug: Naltrexone
2 Completed Dopamine and Opioid Receptor Antagonists Reduce Cue-induced Reward Responding and Reward Impulsivity
Condition: Addiction
Interventions: Drug: Placebo;   Drug: Amisulpride;   Drug: Naltrexone
3 Terminated Opioid Agonist and Antagonist Effects on Opioid Dependence
Condition: Opioid-Related Disorders
Interventions: Drug: Methadone;   Drug: Full opioid agonist;   Drug: Partial opioid agonist;   Drug: Opioid antagonist
4 Completed The Comparison of Stress Response to Rapid Opioid Detoxification Applying Different Methods of Opioid Antagonism
Condition: Opiate Addiction
Interventions: Drug: Naltrexone;   Drug: Clonidine;   Drug: Lorazepam
5 Completed An Open-Label Evaluation of the Independent Effects of Coadministration of a High-Fat Meal and Naltrexone Blockade on the Pharmacokinetic Profile of Dilaudid OROS (Hydromorphone HCI) 16mg
Condition: Analgesia
Intervention: Drug: Hydromorphone HCL 16mg; Dilaudid SR 16mg; Naltrexone (opioid antagonist) 50mg.
6 Completed An Open-Label Evaluation of the Dose Proportionality of OROS� Hydromorphone HCL Tablets 8mg, 16mg, 32mg, 64mg
Condition: Analgesia
Intervention: Drug: OROS® Hydromorphone HCL; OROS® Dilaudid; Dilaudid SR (slow release); Naltrexone (an opioid antagonist).
7 Recruiting Fast-Fail Trials in Mood and Anxiety Spectrum Disorders; Kappa Opioid Receptor Phase 2a
Condition: ANXIETY DISORDERS (or Anxiety and Phobic Neuroses)
Interventions: Drug: CERC-501;   Drug: placebo
8 Recruiting Extended-release Naltrexone and Care Management for Alcohol Dependent Frequent Emergency Department Users
Conditions: Alcohol Dependence;   Alcohol Use Disorder
Intervention: Drug: XR-NTX+CM (Extended-Release Naltrexone plus Care Management)
9 Terminated Cardiovascular Outcomes Study of Naltrexone SR/Bupropion SR in Overweight and Obese Subjects With Cardiovascular Risk Factors (The Light Study)
Conditions: Obesity;   Overweight
Interventions: Drug: NB32;   Drug: PBO;   Behavioral: Weight Management Program
10 Active, not recruiting Comparison of Two Naloxone Infusion Rates on the Postoperative Recovery of Patients Undergoing Spine Fusion Surgery
Conditions: Pain, Postoperative;   Postoperative Nausea and Vomiting;   Scoliosis
Intervention: Drug: Naloxone
11 Completed
Has Results
Methylnaltrexone for Opioid-induced Constipation in Cancer Patients
Conditions: Neoplasms;   Constipation;   Opioid-Related Disorders
Intervention: Drug: Methylnaltrexone bromide
12 Unknown  Buprenorphine's Dose Response Curve
Condition: Opioid-related Disorders
Interventions: Drug: Buprenorphine;   Drug: Morphine;   Drug: Placebo
13 Completed Naloxone and Intravenous Methylnaltrexone Effects on Bladder Function
Condition: Healthy Males
Interventions: Drug: Naloxone;   Drug: IV Methylnaltrexone (MNTX);   Drug: Placebo
14 Terminated Naltrexone in Borderline Personality Disorder
Condition: Borderline Personality Disorder
Intervention: Drug: Naltrexone
15 Recruiting Effect of Methylnaltrexone on the PK/PD Profiles of Ticagrelor in Patients Treated With Morphine
Condition: Coronary Artery Disease
Interventions: Drug: Methylnaltrexone;   Other: Placebo;   Drug: Morphine;   Drug: Ticagrelor
16 Unknown  Methylnaltrexone Pharmacokinetics in Neurointensive Care Patients
Condition: Opioid Use, Unspecified With Other Opioid-induced Disorder
Intervention: Drug: Methylnaltrexone
17 Active, not recruiting Investigation of Naltrexone for Pathological Gambling
Condition: Pathological Gambling
Interventions: Drug: Naltrexone;   Other: Placebo
18 Terminated Naltrexone Implants as Relapse Prevention
Condition: Opioid Dependency
Intervention: Drug: Implantation of naltrexone implants
19 Withdrawn HIV Risk Reduction and Drug Abuse Treatment in Iran
Conditions: Opiate Dependence;   HIV Infections
Interventions: Drug: Buprenorphine/Subutex;   Drug: Naltrexone;   Behavioral: Drug counseling
20 Not yet recruiting The Effect of Regular Naltrexone Dosing on Disordered Gamblers
Condition: Gambling
Intervention: Drug: Naltrexone

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Indicates status has not been verified in more than two years