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905 studies found for:    "Narcotic Antagonists"
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Rank Status Study
1 Recruiting The Impact of the Opiate Antagonist Naltrexone on the Emotional Valence of Dreams
Condition: Neuroscience of Dreaming, Healthy
Interventions: Drug: Naltrexone;   Other: Placebo
2 Completed
Has Results
Prevention of Stimulant-Induced Euphoria With an Opioid Receptor Antagonist
Conditions: ADHD;   Stimulant-Induced Euphoria
Interventions: Drug: SODAS MPH;   Drug: Naltrexone
3 Completed An Open-Label Evaluation of the Independent Effects of Coadministration of a High-Fat Meal and Naltrexone Blockade on the Pharmacokinetic Profile of Dilaudid OROS (Hydromorphone HCI) 16mg
Condition: Analgesia
Intervention: Drug: Hydromorphone HCL 16mg; Dilaudid SR 16mg; Naltrexone (opioid antagonist) 50mg.
4 Completed An Open-Label Evaluation of the Dose Proportionality of OROS� Hydromorphone HCL Tablets 8mg, 16mg, 32mg, 64mg
Condition: Analgesia
Intervention: Drug: OROS® Hydromorphone HCL; OROS® Dilaudid; Dilaudid SR (slow release); Naltrexone (an opioid antagonist).
5 Recruiting Fast-Fail Trials in Mood and Anxiety Spectrum Disorders; Kappa Opioid Receptor Phase 2a
Condition: ANXIETY DISORDERS (or Anxiety and Phobic Neuroses)
Interventions: Drug: CERC-501;   Drug: placebo
6 Completed Dopamine and Opioid Receptor Antagonists Reduce Cue-induced Reward Responding and Reward Impulsivity
Condition: Addiction
Interventions: Drug: Placebo;   Drug: Amisulpride;   Drug: Naltrexone
7 Recruiting Naloxegol Health Outcomes PASS
Condition: Opioid Induced Constipation
Interventions: Drug: naloxegol;   Drug: non-PAMORA laxative
8 Terminated Opioid Agonist and Antagonist Effects on Opioid Dependence
Condition: Opioid-Related Disorders
Interventions: Drug: Methadone;   Drug: Full opioid agonist;   Drug: Partial opioid agonist;   Drug: Opioid antagonist
9 Completed The Comparison of Stress Response to Rapid Opioid Detoxification Applying Different Methods of Opioid Antagonism
Condition: Opiate Addiction
Interventions: Drug: Naltrexone;   Drug: Clonidine;   Drug: Lorazepam
10 Recruiting Naloxegol US PMR CV Safety
Condition: Opioid Induced Constipation
Interventions: Drug: naloxegol;   Drug: non-PAMORA
11 Completed Naloxone and Intravenous Methylnaltrexone Effects on Bladder Function
Condition: Healthy Males
Interventions: Drug: Naloxone;   Drug: IV Methylnaltrexone (MNTX);   Drug: Placebo
12 Terminated Naltrexone in Borderline Personality Disorder
Condition: Borderline Personality Disorder
Intervention: Drug: Naltrexone
13 Active, not recruiting Buprenorphine's Dose Response Curve
Condition: Opioid-related Disorders
Interventions: Drug: Buprenorphine;   Drug: Morphine;   Drug: Placebo
14 Completed Effect of Methylnaltrexone on the PK/PD Profiles of Ticagrelor in Patients Treated With Morphine
Condition: Coronary Artery Disease
Interventions: Drug: Methylnaltrexone;   Other: Placebo;   Drug: Morphine;   Drug: Ticagrelor
15 Recruiting The Effect of Regular Naltrexone Dosing on Disordered Gamblers
Condition: Gambling
Intervention: Drug: Naltrexone
16 Completed Study of Long-Acting Injectable Naltrexone to Treat Cannabis Dependence
Condition: Cannabis Dependence
Intervention: Drug: Long-acting injectable naltrexone
17 Terminated Proof-of-Concept Trial of CERC-501 Augmentation of Antidepressant Therapy in Treatment-Resistant Depression
Condition: Treatment Resistant Depression
Interventions: Drug: CERC-501;   Drug: Placebo
18 Completed A Study to Assess How the Body Processes a Strong Painkiller When it is Given Alongside a Drug That Counteracts the Side Effects of Strong Painkillers in a Fasted and Fed State.
Condition: Pain
Interventions: Drug: 4 mg 12 hourly capsule - strong pain killer fasted;   Drug: 4 mg 12 hourly capsule - strong pain killer fed;   Drug: 12 hourly capsule strong painkiller with antagonist fasted);   Drug: 4 mg 12 hourly capsule strong painkiller with antagonist fed
19 Completed ALK33-001: A Study of RDC-0313 Administered to Healthy Adults
Condition: Alcohol Dependence
Interventions: Drug: RDC-0313;   Drug: Placebo
20 Active, not recruiting Investigation of Naltrexone for Pathological Gambling
Condition: Pathological Gambling
Interventions: Drug: Naltrexone;   Other: Placebo

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Study has passed its completion date and status has not been verified in more than two years.