48613 studies found for:    "Molecular Mechanisms of Pharmacological Action"
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Study Details
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Dates
Rank Status Study
1 Completed Study in Infants With Infantile Hemangioma to Compare Propranolol Gel to Placebo
Condition: Infantile Hemangioma
Interventions: Drug: propranolol gel;   Drug: Placebo
2 Recruiting PET/CT Imaging Study of the Safety and Diagnostic Performance of [68Ga]RM2 in Patients With Primary Prostate Cancer
Condition: Prostate Cancer
Interventions: Drug: [68Ga]RM2;   Procedure: PET/CT
3 Recruiting Prospective Observational Study Of Patients With Polycythemia Vera In US Clinical Practices (REVEAL)
Condition: Polycythemia Vera
Intervention:
4 Active, not recruiting Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of GS-9857 in Subjects With Chronic Hepatitis C Virus Infection
Condition: Hepatitis C Virus Infection
Interventions: Drug: GS-9857;   Drug: Placebo to match GS-9857;   Drug: SOF/GS-5816
5 Recruiting Study of Patritumab in Combination With Erlotinib in Subjects With Locally Advanced or Metastatic Non-Small-Cell Lung Cancer (NSCLC). (HER3-Lung)
Conditions: Lung Cancer;   Non Small Cell Lung Cancer.
Interventions: Drug: Patritumab;   Drug: erlotinib:;   Drug: Placebo
6 Recruiting A Multicenter Phase 3, Open-Label Study of Bosutinib Versus Imatinib in Adult Patients With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia
Condition: Leukemia, Myelogenous, Chronic, Breakpoint Cluster Region-Abelson Proto-oncogene (BCR-ABL) Positive
Interventions: Drug: Bosutinib;   Drug: Imatinib
7 Recruiting Resveratrol and First-degree Relatives of Type 2 Diabetic Patients
Condition: Pre-diabetes
Interventions: Dietary Supplement: placebo;   Dietary Supplement: resveratrol
8 Completed
Has Results
Open-label, Single-arm Study to Assess the Pharmacokinetics, Safety, and Tolerability of a Single Subcutaneous Dose of Icatibant in Healthy Japanese Volunteers
Condition: Hereditary Angioedema (HAE)
Intervention: Drug: Icatibant (30 mg)
9 Recruiting Tranexamic Acid in Reverse Total Shoulder Arthroplasty
Conditions: Shoulder Joint Disease;   Complications; Arthroplasty;   Intraoperative Complications;   Blood Loss, Surgical
Intervention: Drug: Infusion Tranexamic acid or placebo.
10 Completed A Study of MK-0893 on Glucagon-Induced Glycemic Excursion in Healthy Male Participants Following Intravenous Administration of Glucagon, Sandostatine® and Insulin (MK-0893-002)
Condition: Type 2 Diabetes Mellitus
Interventions: Drug: MK-0893 10 mg;   Drug: MK-0893 40 mg;   Drug: MK-0893 200 mg;   Drug: MK-0893 1000 mg;   Drug: Placebo;   Biological: Sandostatine®;   Biological: Insulin;   Biological: Glucagon
11 Completed
Has Results
A Study to Assess the Safety, Tolerability and Glucose-Lowering Efficacy of MK-0893 in Participants With Type 2 Diabetes Mellitus (MK-0893-005)
Condition: Type 2 Diabetes Mellitus
Interventions: Drug: MK-0893;   Drug: Metformin;   Drug: Placebo
12 Recruiting Pharmacogenetic Trial of Doxazosin for Treatment of Cocaine Abuse
Condition: Cocaine Dependence
Interventions: Drug: Doxazosin;   Drug: Placebo
13 Completed
Has Results
Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed-Dose Combination ± Ribavirin for the Treatment of HCV (ION-3)
Condition: Chronic Hepatitis C Virus
Interventions: Drug: LDV/SOF;   Drug: RBV
14 Completed
Has Results
Sofosbuvir Plus Ribavirin Administered for Either 12 or 24 Weeks in Treatment-Naive and Treatment-Experienced Egyptian Adults With Chronic Genotype 4 Hepatitis C Virus (HCV) Infection
Condition: Hepatitis C Virus
Interventions: Drug: SOF;   Drug: RBV
15 Completed Effect of Magnesium on the Recovery Time of Neuromuscular Blockade With Sugammadex
Condition: Neuromuscular Blockade
Interventions: Drug: Magnesium Sulfate;   Drug: Saline
16 Completed
Has Results
Sofosbuvir (GS-7977) in Combination With PEG and Ribavirin for 12 Weeks in Treatment Experienced Subjects With Chronic HCV Infection Genotype 2 or 3
Condition: Hepatitis C
Interventions: Drug: SOF;   Drug: PEG;   Drug: RBV
17 Suspended A Prospective Open Label Comparative Dose Ranging Study Evaluating the Effect of Pre-TURBT Intravesical Instillation of Mitomycin C (MMC) Mixed With TC-3 Gel in Patients With Non Muscle Invasive Bladder Cancer (NMIBC)
Condition: Non Muscle Invasive Bladder Cancer
Intervention: Device: TC-3 hydrogel
18 Approved for marketing Expanded Access Program of Sofosbuvir With Ribavirin and With or Without Pegylated Interferon in Aggressive Post-transplant Hepatitis C
Condition: Post-transplant Hepatitis C
Interventions: Drug: Sofosbuvir;   Drug: Ribavirin;   Drug: Pegylated Interferon
19 Completed
Has Results
Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed-Dose Combination ± Ribavirin in Treatment-Experienced Subjects With Genotype 1 HCV Infection
Condition: Chronic Hepatitis C Virus
Interventions: Drug: LDV/SOF;   Drug: RBV
20 Recruiting A Study of Vitamin C in the Treatment of Liver Cancer to Determine if it is Safe and Effective
Conditions: Metastatic Hepatocellular Carcinoma;   Advanced Liver Cancer
Interventions: Drug: Ascorbic Acid + Sorafenib;   Drug: Sorafenib alone

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Indicates status has not been verified in more than two years