46950 studies found for:    "Molecular Mechanisms of Pharmacological Action"
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Study Details
Participant Details
Identifiers
Dates
Rank Status Study
1 Completed Study in Infants With Infantile Hemangioma to Compare Propranolol Gel to Placebo
Condition: Infantile Hemangioma
Interventions: Drug: propranolol gel;   Drug: Placebo
2 Recruiting Pharmacogenetic Trial of Doxazosin for Treatment of Cocaine Abuse
Condition: Cocaine Dependence
Interventions: Drug: Doxazosin;   Drug: Placebo
3 Recruiting Tranexamic Acid in Reverse Total Shoulder Arthroplasty
Conditions: Shoulder Joint Disease;   Complications; Arthroplasty;   Intraoperative Complications;   Blood Loss, Surgical
Intervention: Drug: Infusion Tranexamic acid or placebo.
4 Completed Ezetimibe In Addition To Atorvastatin Therapy On The Plaque Composition In Patients With Acute Myocardial Infarction.
Condition: ST-Segment Elevation Myocardial Infarction
Interventions: Drug: Ezetimibe;   Drug: Placebo
5 Completed Modufolin (6R 5,10-Methylenetetrahydrofolate) and Pemetrexed for Neoadjuvant Rectal Cancer Treatment
Condition: Rectal Cancer
Interventions: Drug: [6R] 5,10-methylenetetrahydrofolate;   Drug: Pemetrexed
6 Completed A Study of MK-0893 on Glucagon-Induced Glycemic Excursion in Healthy Male Participants Following Intravenous Administration of Glucagon, Sandostatine® and Insulin (MK-0893-002)
Condition: Type 2 Diabetes Mellitus
Interventions: Drug: MK-0893 10 mg;   Drug: MK-0893 40 mg;   Drug: MK-0893 200 mg;   Drug: MK-0893 1000 mg;   Drug: Placebo;   Biological: Sandostatine®;   Biological: Insulin;   Biological: Glucagon
7 Suspended Research Into the Effect of a Clot-dissolving Agent and Its Inhibitor
Condition: Acute Ischemic Stroke
Intervention:
8 Completed A Phase 1 Dose-Escalation Study in Advanced Solid Tumors, Lymphomas or Multiple Myeloma
Conditions: Malignant Solid Tumor;   Lymphomas;   Multiple Myeloma
Interventions: Biological: AV-299;   Biological: AV-299 + erlotinib
9 Completed
Has Results
Open-label, Single-arm Study to Assess the Pharmacokinetics, Safety, and Tolerability of a Single Subcutaneous Dose of Icatibant in Healthy Japanese Volunteers
Condition: Hereditary Angioedema (HAE)
Intervention: Drug: Icatibant (30 mg)
10 Recruiting Resveratrol and First-degree Relatives of Type 2 Diabetic Patients
Condition: Pre-diabetes
Interventions: Dietary Supplement: placebo;   Dietary Supplement: resveratrol
11 Active, not recruiting Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of GS-9857 in Subjects With Chronic Hepatitis C Virus Infection
Condition: Hepatitis C Virus Infection
Interventions: Drug: GS-9857;   Drug: Placebo to match GS-9857;   Drug: SOF/GS-5816
12 Active, not recruiting Tecemotide (L-BLP25) in Rectal Cancer
Condition: Rectal Cancer
Interventions: Other: Chemoradiation Therapy;   Drug: Cyclophosphamide (CPA);   Other: Biological: Tecemotide (L-BLP25)
13 Recruiting Study of Patritumab in Combination With Erlotinib in Subjects With Locally Advanced or Metastatic Non-Small-Cell Lung Cancer (NSCLC). (HER3-Lung)
Conditions: Lung Cancer;   Non Small Cell Lung Cancer.
Interventions: Drug: Patritumab;   Drug: erlotinib:;   Drug: Placebo
14 Terminated
Has Results
SGN-30 and Combination Chemotherapy in Treating Patients With Newly Diagnosed Anaplastic Large Cell Lymphoma
Condition: Anaplastic Large Cell Lymphoma
Interventions: Drug: Cyclophosphamide;   Drug: Doxorubicin hydrochloride;   Drug: vincristine sulfate;   Drug: prednisone;   Drug: SGN-30
15 Unknown  Cardiovascular Effects of Salvia Miltiorrhiza Extract (Danshen)
Conditions: Dyslipidemias;   Hypertension;   Vasodilation;   Oxidative Stress;   Inflammation
Interventions: Dietary Supplement: Salvia miltiorrhiza extract;   Dietary Supplement: Placebo
16 Completed Phase 2 Study of ET-743 (Trabectedin) in Patients With Persistent or Recurrent Endometrial Carcinoma
Conditions: Endometrial Neoplasms;   Uterine Neoplasms;   Genital Neoplasms, Female Urogenital Neoplasms
Interventions: Drug: Trabectedin;   Drug: Dexamethasone
17 Completed
Has Results
Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed-Dose Combination (FDC) With and Without Ribavirin for the Treatment of HCV
Condition: Chronic Hepatitis C Virus
Interventions: Drug: LDV/SOF;   Drug: RBV
18 Recruiting Randomized Study of Combination Chemotherapy With or Without Focused Microwave Thermotherapy Before Surgery in Treating Women With Large Breast Cancer Tumors
Condition: Breast Cancer
Interventions: Device: Focused Microwave Thermotherapy;   Drug: Chemotherapy (control)
19 Completed
Has Results
Study of Azacitidine in Adult Taiwanese Subjects With Higher-Risk Myelodysplastic Syndromes (MDS)
Condition: Myelodysplastic Syndromes
Intervention: Drug: Azacitidine
20 Completed
Has Results
Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed-Dose Combination ± Ribavirin for the Treatment of HCV (ION-3)
Condition: Chronic Hepatitis C Virus
Interventions: Drug: LDV/SOF;   Drug: RBV

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