4343 studies found for:    "Antineoplastic Agents, Alkylating"
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Rank Status Study
1 Recruiting Denintuzumab Mafodotin (SGN-CD19A) Combined With RCHOP or RCHP Versus RCHOP Alone in Diffuse Large B-Cell Lymphoma or Follicular Lymphoma
Conditions: Diffuse, Large B-Cell, Lymphoma;   Follicular Lymphoma, Grade 3b;   Transformed Lymphoma / DLBCL
Interventions: Drug: denintuzumab mafodotin;   Drug: rituximab;   Drug: cyclophosphamide;   Drug: doxorubicin;   Drug: vincristine;   Drug: prednisone
2 Recruiting PTCy and Ruxolitinib GVHD Prophylaxis in Myelofibrosis
Conditions: Primary Myelofibrosis;   Myeloproliferative Disorders
Interventions: Procedure: Allogeneic hematopoietic stem cell transplantation;   Drug: Busulfan;   Drug: Fludarabine monophosphate;   Drug: Cyclophosphamide;   Drug: Ruxolitinib
3 Recruiting GVHD Prophylaxis With Post-transplantation Bendamustine in Refractory Leukemia
Conditions: Leukemia, Acute Lymphoblastic;   Acute Myeloid Leukemia;   Mixed-Lineage Acute Leukemias
Interventions: Procedure: Allogeneic stem cell transplantation;   Drug: Fludarabine monophosphate;   Drug: Busulfan;   Drug: Bendamustine
4 Recruiting Trial of GVHD Prophylasxis With PTCy or Thymoglobulin in Unrelated SCT
Conditions: Leukemia, Chronic Myeloid;   Myelodysplastic Syndromes;   Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative
Interventions: Procedure: Unrelated allogeneic stem cell transplantation;   Drug: Busulfan;   Drug: Fludarabine monophosphate;   Drug: Tacrolimus;   Drug: Mycophenolate mofetil;   Drug: Cyclophosphamide;   Drug: Thymoglobulin
5 Active, not recruiting Post-transplantation Cyclophosphamide as GVHD Prophylaxis After HSCT
Conditions: Acute Myeloid Leukemia;   Acute Lymphoid Leukemia;   Lymphoma;   Myelodysplastic Syndromes;   Chronic Lymphocytic Leukemia;   Immune System Diseases
Interventions: Drug: Cyclophosphamide;   Drug: Busulfan;   Drug: Fludarabine monophosphate;   Drug: Tacrolimus;   Drug: Mycophenolate mofetil;   Procedure: Allogeneic hematopoietic stem cell transplantation
6 Recruiting Randomized Study of Combination Chemotherapy With or Without Focused Microwave Thermotherapy Before Surgery in Treating Women With Large Breast Cancer Tumors
Condition: Breast Cancer
Interventions: Device: Focused Microwave Thermotherapy;   Drug: Chemotherapy (control)
7 Terminated
Has Results
SGN-30 and Combination Chemotherapy in Treating Patients With Newly Diagnosed Anaplastic Large Cell Lymphoma
Condition: Anaplastic Large Cell Lymphoma
Interventions: Drug: Cyclophosphamide;   Drug: Doxorubicin hydrochloride;   Drug: vincristine sulfate;   Drug: prednisone;   Drug: SGN-30
8 Completed A Study of Trabectedin in Patients With Advanced Ovarian Cancer
Conditions: Ovarian Neoplasms;   Endocrine Gland Neoplasms;   Neoplasms by Site;   Neoplasms;   Ovarian Diseases;   Adnexal Diseases;   Genital Diseases, Female
Interventions: Drug: Trabectedin;   Drug: Dexamethasone
9 Completed A Study on the Effect of Chemotherapy Combined With Anti-HIV Drugs in HIV-Positive Patients
Condition: HIV Infections
Interventions: Drug: Nelfinavir mesylate;   Drug: Lamivudine;   Drug: Filgrastim;   Drug: Stavudine;   Drug: Cyclophosphamide
10 Completed A Study of ET-743 (Trabectedin) in Patients With Advanced Breast Cancer
Conditions: Breast Neoplasms;   Neoplasms;   Neoplasms by Site;   Breast Diseases;   Skin Diseases
Intervention: Drug: ET743
11 Not yet recruiting Disulfiram in Recurrent Glioblastoma
Conditions: Glioma;   Glioblastoma
Interventions: Drug: Disulfiram;   Dietary Supplement: Copper;   Drug: Alkylating Agents
12 Recruiting Optimization of Therapy in Adult Patients With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma by Individualised, Targeted and Intensified Treatment
Conditions: Acute Lymphoblastic Leukemia;   Lymphoblastic Lymphoma
Interventions: Drug: Rituximab;   Drug: Nelarabine;   Drug: PEG-Asparaginase;   Procedure: Cranial irradiation;   Drug: Imatinib;   Drug: Idarubicin;   Drug: Dexamethasone;   Drug: Cyclophosphamide;   Drug: Fludarabine;   Drug: Vincristine;   Drug: Mercaptopurine;   Drug: VP16;   Drug: Daunorubicin (DNR);   Drug: Methotrexate;   Procedure: Stem cell transplantation;   Drug: Cytarabine;   Drug: Vindesine;   Drug: Adriamycin;   Drug: Prednisolone
13 Not yet recruiting Feasibility Study on LITT for Newly Diagnosed Glioblastoma
Condition: Glioblastoma
Intervention: Device: NeuroBlate System
14 Recruiting Haploidentical (Half-matched) Related Donor Stem Cell Transplantation Using Killer Immunoglobulin-like Receptors in Addition to Normal Selection Factors to Determine the Best Donor
Conditions: Leukemia;   Hematologic Malignancy
Interventions: Drug: melphalan;   Drug: fludarabine;   Drug: thiotepa;   Drug: Cyclophosphamide;   Drug: Mesna;   Drug: Mycophenolate Mofetil;   Drug: Filgrastim;   Drug: Tacrolimus
15 Recruiting A Randomised Phase II Open-label Study With a Phase Ib Safety lead-in Cohort of ONCOS-102, an Immune-priming GM-CSF Coding Oncolytic Adenovirus, and Pemetrexed/Cisplatin in Patients With Unresectable Malignant Pleural Mesothelioma
Condition: To Determine Safety, Tolerability and Efficacy of ONCOS-102 in Combination With Chemotherapy
Interventions: Biological: ONCOS-102;   Drug: Pemetrexed/cisplatin;   Drug: Cyclophosphamide
16 Recruiting Chidamide Combined With Cyclophosphamide、Prednisone、Thalidomide in Treatment of Fragile Patients With Relapse/Refratory Peripheral T Cell Lymphoma
Condition: Relapse/Refratory Peripheral T Cell Lymphoma
Intervention: Drug: C-CPT
17 Recruiting Trial of Adjuvant Chemotherapy in Breast Cancer Patients With Pathological Partial Response to Neoadjuvant Chemotherapy
Conditions: Invasive Ductal Breast Cancer;   Tubular Breast Cancer;   Mucinous Breast Cancer;   Inflammatory Breast Cancer
Interventions: Drug: Paclitaxel;   Drug: Cisplatin;   Drug: Epirubicin;   Drug: Cyclophosphamide;   Drug: 5-fluoruracil
18 Not yet recruiting Hyper-CVAD Regimen in Sequential Combination With Blinatumomab as Frontline Therapy for Adults With B-Cell Lineage Acute Lymphocytic Leukemia
Conditions: Leukemia;   Acute Lymphoblastic Leukemia
Interventions: Drug: Cyclophosphamide;   Drug: MESNA;   Drug: Dexamethasone;   Drug: Ofatumumab;   Drug: Methotrexate;   Drug: Doxorubicin;   Drug: Vincristine;   Drug: Cytarabine;   Drug: Rituximab;   Drug: Pegfilgrastim;   Drug: G-CSF;   Drug: Leucovorin;   Drug: Blinatumomab;   Drug: 6-Mercaptopurine;   Drug: Prednisone;   Behavioral: Phone Calls
19 Recruiting Anti-GPC3 CAR T for Recurrent or Refractory Lung Squamous Cell Carcinoma
Condition: Lung Squamous Cell Carcinoma
Interventions: Genetic: CAR-GPC3 T Cells;   Drug: Fludarabine;   Drug: Cyclophosphamide
20 Not yet recruiting Cyclophosphamide Versus Anti-thymocyte Globulin for GVHD Prophylaxis After RIC Allo-SCT
Condition: Graft vs Host Disease
Interventions: Drug: Cyclophosphamide;   Drug: Anti-Thymocyte Globulin;   Drug: Conditioning regimen

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Indicates status has not been verified in more than two years