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332 studies found for:    "Alkylating Agents" | Studies updated in the last 30 days
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Rank Status Study
1 Recruiting Radiation- and Alkylator-free Bone Marrow Transplantation Regimen for Patients With Dyskeratosis Congenita
Conditions: Dyskeratosis Congenita;   Hoyeraal Hreidarsson Syndrome;   Revesz Syndrome;   Aplastic Anemia
Interventions: Biological: alemtuzumab;   Drug: Fludarabine;   Drug: Cyclosporins;   Drug: Mycophenolate mofetil
2 Completed Fludarabine and Cyclophosphamide in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Chronic Lymphocytic Leukemia or Waldenstrom's Macroglobulinemia
Condition: Chronic Lymphocytic Leukemia
Interventions: Biological: alemtuzumab;   Biological: anti-thymocyte globulin;   Biological: filgrastim;   Biological: rituximab;   Biological: therapeutic allogeneic lymphocytes;   Drug: busulfan;   Drug: cyclophosphamide;   Drug: cyclosporine;   Drug: fludarabine phosphate;   Drug: methotrexate;   Drug: mycophenolate mofetil;   Procedure: peripheral blood stem cell transplantation;   Radiation: radiation therapy
3 Recruiting Auto Transplant for High Risk or Relapsed Solid or CNS Tumors
Conditions: Ewing's Family Tumors;   Renal Tumors;   Hepatoblastoma;   Rhabdomyosarcoma;   Soft Tissue Sarcoma;   Primary Malignant Brain Neoplasms;   Retinoblastoma;   Medulloblastoma;   Supra-tentorial Primative Neuro-Ectodermal Tumor (PNET);   Atypical Teratoid/Rhabdoid Tumor (AT/RT);   CNS Tumors;   Germ Cell Tumors
Interventions: Drug: Ifosfamide;   Drug: Etoposide;   Drug: Mesna;   Biological: G-CSF;   Drug: Busulfan;   Drug: Melphalan;   Drug: Thiotepa;   Biological: Autologous stem cell infusion;   Radiation: Radiation;   Drug: Carboplatin;   Drug: Paclitaxel;   Procedure: Leukapheresis
4 Not yet recruiting ATG Combined With Cyclophosphamide And Cord Blood Transfusion in Treating Patients With Severe Aplastic Anemia
Condition: Aplastic Anemia
Interventions: Drug: Rabbit ATG, (Genzyme);   Drug: Cy;   Drug: CsA;   Biological: Cord blood
5 Active, not recruiting Combination Of Lapatinib With Carboplatin, Paclitaxel and Trastuzumab In Metastatic Breast Cancer
Condition: Neoplasms, Breast
Interventions: Drug: lapatinib;   Drug: carboplatin;   Drug: trastuzumab;   Drug: paclitaxel
6 Recruiting Denintuzumab Mafodotin (SGN-CD19A) Combined With RCHOP or RCHP Versus RCHOP Alone in Diffuse Large B-Cell Lymphoma or Follicular Lymphoma
Conditions: Diffuse, Large B-Cell, Lymphoma;   Follicular Lymphoma, Grade 3b;   Transformed Lymphoma / DLBCL
Interventions: Drug: denintuzumab mafodotin;   Drug: rituximab;   Drug: cyclophosphamide;   Drug: doxorubicin;   Drug: vincristine;   Drug: prednisone
7 Active, not recruiting Impact of Sunflower Seed Oil Massage on Neonatal Mortality and Morbidity in Nepal
Conditions: Neonatal Mortality;   Neonatal Sepsis
Interventions: Other: Sunflower seed oil;   Other: Mustard seed oil
8 Not yet recruiting Safety Study of VAL-083 and Radiotherapy in Patients With Newly Diagnosed GBM Having Unmethylated MGMT Expression
Conditions: Glioma;   Glioblastoma;   Glioblastoma Multiforme;   GBM;   Brain Cancer
Intervention: Drug: VAL-083 (Dianhydrogalactitol)
9 Recruiting Geriatric Assessmen of Elderly "Unsuited" Patients Receiving Trabectedin in First Line Treatment For Advanced Soft Tissue Sarcomas (STS)
Conditions: Advanced Soft-tissue Sarcoma;   Metastatic Soft-tissue Sarcoma
Intervention: Other: No Intervention
10 Recruiting INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)
Condition: Glioblastoma
Interventions: Drug: Temozolomide;   Drug: Neratinib;   Drug: CC-115;   Drug: Abemaciclib
11 Withdrawn Autologous Stem Cell Collection and Reinfusion in Newly Diagnosed High Grade Gliomas
Conditions: Astrocytoma;   Brainstem Glioma;   Ependymoma;   Mixed Glioma;   Oligodendroglioma;   Optic Nerve Glioma
Interventions: Radiation: Radiation therapy;   Drug: Temozolomide;   Procedure: Stem cell collection;   Procedure: Stem cell infusion
12 Not yet recruiting Phase 1 Two Part Dose Escalation Trial of RRx-001 + Radiation + Temozolomide and RRx-001 + Temozolomide Post-RT In Newly Diagnosed Glioblastoma and Anaplastic Gliomas
Conditions: Glioblastoma;   Oligodendroglioma;   Anaplastic Oligodendroglioma
Interventions: Drug: RRx-001 dose escalation with TMZ + RT;   Radiation: Radiation;   Drug: Fixed dose Temozolomide (75 mg/m2);   Drug: Fixed RRx-001 weekly;   Drug: Staged TMZ and RRx-001 escalation in maintenance stage;   Drug: TMZ Maintenance
13 Recruiting Temozolomide Chronotherapy for High Grade Glioma
Conditions: Glioma;   Glioblastoma Multiforme
Interventions: Drug: Temozolomide;   Other: Functional Assessment of Cancer Therapy - Brain
14 Recruiting Phase 1/2 Study of USL311 Alone and in Combination With Lomustine in Subjects With Advanced Solid Tumors and Relapsed/Recurrent Glioblastoma Multiforme (GBM)
Conditions: Solid Tumors (Phase 1);   Relapsed/Recurrent GBM (Phase 2)
Interventions: Drug: USL311;   Drug: Lomustine
15 Recruiting Study Evaluating ABT-414 in Japanese Subjects With Malignant Glioma
Conditions: Malignant Glioma;   Glioblastoma
Interventions: Drug: ABT-414;   Drug: Temozolomide;   Radiation: Whole Brain Radiation
16 Recruiting Phase 3 Randomized, Double-blind, Controlled Study of ICT-107 in Glioblastoma
Condition: Glioblastoma Multiforme
Interventions: Biological: ICT-107;   Biological: Placebo
17 Recruiting Methoxyamine and Temozolomide in Treating Patients With Recurrent Glioblastoma
Condition: Adult Brain Glioblastoma
Interventions: Other: Laboratory Biomarker Analysis;   Drug: Methoxyamine;   Drug: Temozolomide
18 Recruiting Adult Study: ABT-414 Alone or ABT-414 Plus Temozolomide vs. Lomustine or Temozolomide for Recurrent Glioblastoma Pediatric Study: Evaluation of ABT-414 in Children With High Grade Gliomas
Condition: Glioblastoma Multiforme
Interventions: Drug: ABT-414;   Drug: Lomustine;   Drug: Temozolomide
19 Recruiting Phase I/II Study of Pazopanib+ Temozolomide in Patients With Newly Diagnosed Glioblastoma Multiforme
Condition: Glioblastoma Multiforme
Intervention: Drug: Pazopanib
20 Recruiting PV-10 vs Chemotherapy or Oncolytic Viral Therapy for Treatment of Locally Advanced Cutaneous Melanoma
Condition: Melanoma Recurrent
Interventions: Drug: PV-10 (10% rose bengal disodium);   Drug: Dacarbazine, temozolomide or talimogene laherparepvec

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Study has passed its completion date and status has not been verified in more than two years.