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367 studies found for:    "Alkylating Agents" | Studies updated in the last 30 days
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Rank Status Study
1 Recruiting Disulfiram in Recurrent Glioblastoma
Conditions: Glioma;   Glioblastoma
Interventions: Drug: Disulfiram;   Dietary Supplement: Copper;   Drug: Alkylating Agents
2 Recruiting HUMC 1612: Optune NovoTTF-200A System
Condition: High Grade Glioma
Interventions: Device: Optune NovoTTF-200A System;   Drug: Bevacizumab;   Drug: Temozolomide
3 Recruiting Reduced-Intensity Conditioning (RIC) and Myeloablative Conditioning (MAC) for HSCT in AML/MDS
Conditions: Acute Myeloid Leukemia (AML);   Myelodysplastic Syndrome (MDS);   Hematopoietic Stem Cell Transplant (HSCT)
Interventions: Drug: Reduced-Intensity Conditioning Regimen;   Drug: Myeloablative Conditioning Regimen
4 Terminated Busulfan in Multiple Myeloma
Condition: Multiple Myeloma
Intervention: Drug: Busulfan
5 Terminated Ph 3 Trial of Blinatumomab vs Investigator's Choice of Chemotherapy in Patients With Relapsed or Refractory ALL
Condition: Adult Subjects With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia
Interventions: Drug: Blinatumomab;   Drug: Standard of Care Chemotherapy
6 Recruiting A Phase II Study of Ibrutinib Plus FCR in Previously Untreated, Younger Patients With Chronic Lymphocytic Leukemia
Conditions: Chronic Lymphocytic Leukemia;   Leukemia
Interventions: Drug: Ibrutinib;   Drug: Fludarabine;   Drug: Cyclophosphamide;   Drug: Rituximab
7 Recruiting Chemotherapy +/- Nivolumab in Patients With Intermediate and High-Risk Local-Regionally Advanced Head and Neck Squamous Cell Carcinoma
Condition: Head and Neck Squamous Cell Carcinoma (HNSCC)
Interventions: Drug: Nivolumab;   Drug: Cisplatin;   Drug: Cetuximab;   Radiation: IMRT
8 Completed To Study the Beneficial Effect of Mustard Oil and Salt Massaging With Oral Prophylaxis in Patients With Gum Diseases
Condition: Chronic Periodontitis
Interventions: Procedure: SCALING AND ROOT PLANING (SRP);   Procedure: MUSTARD OIL AND SALT MASSAGE WITH SRP
9 Recruiting Combination Chemotherapy With or Without Radiation Therapy in Treating Young Patients With Favorable-Risk Hodgkin Lymphoma
Condition: Hodgkin Lymphoma
Interventions: Drug: Stanford V Chemotherapy;   Radiation: Radiation Therapy
10 Not yet recruiting Phase II Venetoclax, Obinutuzumab and Bendamustine in High Tumor Burden Follicular Lymphoma as Front Line Therapy
Conditions: Follicular Lymphoma;   Non-Hodgkin's Lymphoma Follicular;   Non-Hodgkin's Lymphoma, Adult High Grade
Interventions: Drug: Induction Venetoclax;   Drug: Maintenance Venetoclax
11 Not yet recruiting Study of Laser Interstitial Thermal Therapy (LITT) in Recurrent Glioblastoma
Conditions: Malignant Neoplasms of Eye Brain and Other Parts of Central Nervous System;   Glioblastoma;   Anaplastic Astrocytoma
Interventions: Procedure: Laser Interstitial Thermal Therapy;   Drug: Lomustine;   Behavioral: Quality of Life Questionnaires;   Device: The NeuroBlate System
12 Recruiting Radiation Therapy Plus Temozolomide and Pembrolizumab With and Without HSPPC-96 in Newly Diagnosed Glioblastoma (GBM)
Condition: Glioblastoma
Interventions: Drug: Pembrolizumab;   Biological: HSPPC-96;   Drug: Temozolomide;   Other: Placebo;   Radiation: radiation treatment
13 Recruiting INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)
Condition: Glioblastoma
Interventions: Drug: Temozolomide;   Drug: Neratinib;   Drug: CC-115;   Drug: Abemaciclib
14 Recruiting TG02 Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of TG02 Plus Temozolomide Versus Temozolomide Alone in Adults With Recurrent Anaplastic Astrocytoma and Glioblastoma
Conditions: Brain Tumor;   Astrocytoma;   Astroglioma;   Glioblastoma;   Gliosarcoma
Interventions: Drug: TG02;   Drug: TMZ
15 Recruiting Peptide Targets for Glioblastoma Against Novel Cytomegalovirus Antigens
Conditions: Glioblastoma;   Glioblastoma Multiforme
Interventions: Drug: 5-day TMZ;   Drug: 21-day TMZ;   Biological: PEP-CMV;   Drug: Tetanus-Diphtheria booster;   Drug: Tetanus Pre-Conditioning
16 Active, not recruiting Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Pharmacodynamic Effects of PQR309 in Glioblastoma Patients
Condition: Glioblastoma Multiforme
Intervention: Drug: PQR309
17 Recruiting Autologous Cytomegalovirus (CMV)-Specific Cytotoxic T Cells for Glioblastoma (GBM) Patients
Conditions: Glioblastoma;   Gliosarcoma
Interventions: Drug: Temozolomide;   Biological: T Cell Infusion;   Procedure: Surgery;   Behavioral: Phone Calls
18 Recruiting Study Evaluating ABT-414 in Japanese Subjects With Malignant Glioma
Conditions: Malignant Glioma;   Glioblastoma
Interventions: Drug: ABT-414;   Drug: Temozolomide;   Radiation: Whole Brain Radiation
19 Recruiting Phase 3 Randomized, Double-blind, Controlled Study of ICT-107 in Glioblastoma
Condition: Glioblastoma Multiforme
Interventions: Biological: ICT-107;   Biological: Placebo
20 Recruiting A Phase II Study of NovoTTF-200A Alone and With Temozolomide in Patients With Low-Grade Gliomas
Condition: Glioma
Interventions: Device: NovoTTF-200A;   Drug: Temozolomide

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Study has passed its completion date and status has not been verified in more than two years.