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251 studies found for:    "Alkylating Agents" | Studies updated in the last 30 days
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Rank Status Study
1 Recruiting Co-treatment With GnRH Analogs on the Ovarian Reserve in Young Women Treated With Alkylating Agents for Cancer
Conditions: Cancer;   Toxicity Due to Chemotherapy;   Sarcoma;   Osteosarcoma;   Lymphoma;   Ewing Sarcoma
Intervention: Drug: Triptorelin (GnRHa) + Chemotherapy
2 Active, not recruiting Ph 3 Trial of Blinatumomab vs Investigator's Choice of Chemotherapy in Patients With Relapsed or Refractory ALL
Condition: Adult Subjects With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia
Interventions: Drug: Blinatumomab;   Drug: Standard of Care Chemotherapy
3 Recruiting Prospective Pilot Trial to Assess a Multimodal Molecular Targeted Therapy in Children, Adolescent and Young Adults With Relapsed or Refractory High-grade Pineoblastoma
Condition: Pineoblastoma
Interventions: Drug: Temozolomide;   Drug: Irinotecan;   Drug: Dasatinib;   Drug: Rapamycin
4 Recruiting Multimodal Molecular Targeted Therapy to Treat Relapsed or Refractory High-risk Neuroblastoma
Condition: Neuroblastoma Recurrent
Interventions: Drug: Dasatinib;   Drug: Rapamycin;   Drug: Irinotecan;   Drug: Temozolomide
5 Active, not recruiting Combination Of Lapatinib With Carboplatin, Paclitaxel and Trastuzumab In Metastatic Breast Cancer
Condition: Neoplasms, Breast
Interventions: Drug: lapatinib;   Drug: carboplatin;   Drug: trastuzumab;   Drug: paclitaxel
6 Not yet recruiting Study of Laser Interstitial Thermal Therapy (LITT) in Recurrent Glioblastoma
Conditions: Malignant Neoplasms of Eye Brain and Other Parts of Central Nervous System;   Glioblastoma;   Anaplastic Astrocytoma
Interventions: Procedure: Laser Interstitial Thermal Therapy;   Drug: Lomustine;   Behavioral: Quality of Life Questionnaires
7 Not yet recruiting Geriatric Assessmen of Elderly "Unsuited" Patients Receiving Trabectedin in First Line Treatment For Advanced Soft Tissue Sarcomas (STS)
Conditions: Advanced Soft-tissue Sarcoma;   Metastatic Soft-tissue Sarcoma
Intervention: Other: No Intervention
8 Not yet recruiting Phase II/III Trial of CCRT With or Without JP001 for Newly Diagnosed GBM
Condition: Glioblastoma
Interventions: Radiation: CCRT;   Drug: Temozolomide;   Drug: Siroquine
9 Recruiting INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)
Condition: Glioblastoma
Interventions: Drug: Temozolomide;   Drug: Neratinib;   Drug: CC-115;   Drug: Abemaciclib
10 Recruiting Phase 1/2 Study of USL311 Alone and in Combination With Lomustine in Subjects With Advanced Solid Tumors and Relapsed/Recurrent Glioblastoma Multiforme (GBM)
Conditions: Solid Tumors (Phase 1);   Relapsed/Recurrent GBM (Phase 2)
Interventions: Drug: USL311;   Drug: Lomustine
11 Recruiting Autologous Cytomegalovirus (CMV)-Specific Cytotoxic T Cells for Glioblastoma (GBM) Patients
Conditions: Glioblastoma;   Gliosarcoma
Interventions: Drug: Temozolomide;   Biological: T Cell Infusion;   Procedure: Surgery;   Behavioral: Phone Calls
12 Not yet recruiting Symbenda Post-Marketing Surveillance (PMS)
Conditions: Lymphoma, Non-Hodgkin;   Lymphocytic Leukemia;   Multiple Myeloma
Intervention:
13 Recruiting Methoxyamine and Temozolomide in Treating Patients With Recurrent Glioblastoma
Condition: Adult Brain Glioblastoma
Interventions: Other: Laboratory Biomarker Analysis;   Drug: Methoxyamine;   Drug: Temozolomide
14 Recruiting A Study of BBI608 in Combination With Temozolomide in Adult Patients With Recurrent or Progressed Glioblastoma
Condition: Glioblastoma
Interventions: Drug: BBI608;   Drug: Temozolomide
15 Completed Post-Marketing Surveillance of Gliadel 7.7mg Implant (All-case Observational Study)
Condition: Malignant Glioma
Intervention: Other: No intervention
16 Active, not recruiting Post-Marketing Surveillance of Long-Term Observation of Gliadel Wafer-Investigation of Vital Prognosis in Patients With High Grade Glioma
Condition: Malignant Glioma
Intervention: Other: No intervention
17 Recruiting PV-10 vs Chemotherapy or Oncolytic Viral Therapy for Treatment of Locally Advanced Cutaneous Melanoma
Condition: Melanoma Recurrent
Interventions: Drug: PV-10 (10% rose bengal disodium);   Drug: Dacarbazine, temozolomide or talimogene laherparepvec
18 Active, not recruiting A Multi-Center Study of Ibrutinib in Combination With Obinutuzumab Versus Chlorambucil in Combination With Obinutuzumab in Patients With Treatment naïve CLL or SLL
Conditions: Chronic Lymphocytic Leukemia;   Small-Cell Lymphoma
Interventions: Drug: Ibrutinib;   Drug: Obinutuzumab;   Drug: Chlorambucil
19 Recruiting Trabectedin for Recurrent Grade II/III Meningioma
Condition: Recurrent High Grade Meningioma
Interventions: Drug: Trabectedin;   Other: Local standard of care
20 Terminated Stem Cell Radiotherapy and Temozolomide for Newly Diagnosed High-grade Glioma
Conditions: Glioblastoma;   Malignant Glioma;   Brain Tumors;   Anaplastic Astrocytoma
Intervention: Radiation: Stem Cell Radiotherapy (ScRT) and Temozolomide

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Study has passed its completion date and status has not been verified in more than two years.