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289 studies found for:    "Alkylating Agents" | Studies updated in the last 30 days
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Rank Status Study
1 Not yet recruiting Co-treatment With GnRH Analogs on the Ovarian Reserve in Young Women Treated With Alkylating Agents for Cancer
Conditions: Cancer;   Toxicity Due to Chemotherapy;   Sarcoma;   Osteosarcoma;   Lymphoma;   Ewing Sarcoma
Intervention: Drug: Triptorelin (GnRHa) + Chemotherapy
2 Recruiting A Pharmacokinetic Study of Melphalan in Children
Condition: Hematopoietic Stem Cell Transplantation
Intervention: Drug: Melphalan
3 Active, not recruiting Cyclophosphamide for Hematopoietic Stem Cell Mobilization in Patients With a Hematologic Malignancy
Condition: Hematologic Malignancies
Intervention: Drug: Cyclophosphamide
4 Recruiting Efficacy and Safety of Bendamustine Plus Rituximab in Chronic Lympocytic Leukemia
Condition: Chronic Lymphocytic Leukemia
Intervention: Drug: Bendamustine + Rituximab
5 Not yet recruiting Trial To Test Safety And Efficacy Of Vaccination For Incurable HPV 16-Related Oropharyngeal, Cervical And Anal Cancer
Conditions: Cancer of Head and Neck;   Cancer of Cervix;   Cancer of Anus
Interventions: Drug: DPX-E7 vaccine;   Drug: Cyclophosphamide
6 Active, not recruiting Ph 3 Trial of Blinatumomab vs Investigator's Choice of Chemotherapy in Patients With Relapsed or Refractory ALL
Condition: Adult Subjects With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia
Interventions: Drug: Blinatumomab;   Drug: Standard of Care Chemotherapy
7 Recruiting Chemotherapy +/- Nivolumab in Patients With Intermediate and High-Risk Local-Regionally Advanced Head and Neck Squamous Cell Carcinoma
Condition: Head and Neck Squamous Cell Carcinoma (HNSCC)
Interventions: Drug: Nivolumab;   Drug: Cisplatin;   Drug: Cetuximab;   Radiation: IMRT
8 Recruiting Clinical Study Assessing Outcomes, Adverse Events, Treatment Patterns, and Quality of Life in Patients Diagnosed With Mycosis Fungoides Cutaneous T-cell Lymphoma
Condition: Mycosis Fungoides
Intervention: Drug: Valchlor
9 Not yet recruiting INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)
Condition: Glioblastoma
Interventions: Drug: Temozolomide;   Drug: Neratinib;   Drug: CC-115;   Drug: Abemaciclib
10 Not yet recruiting Autologous Stem Cell Collection and Reinfusion in Newly Diagnosed High Grade Gliomas
Conditions: Astrocytoma;   Brainstem Glioma;   Ependymoma;   Mixed Glioma;   Oligodendroglioma;   Optic Nerve Glioma
Interventions: Radiation: Radiation therapy;   Drug: Temozolomide;   Procedure: Stem cell collection;   Procedure: Stem cell infusion
11 Not yet recruiting Expedited Laser Interstitial Thermal Therapy + Chemoradiation For Newly Diagnosed High Grade Gliomas
Condition: High Grade Glioma
Interventions: Procedure: LITT;   Radiation: Radiation therapy;   Drug: Temozolomide
12 Recruiting TG02 Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of TG02 Plus Temozolomide Versus Temozolomide Alone in Adults With Recurrent Anaplastic Astrocytoma and Glioblastoma
Conditions: Brain Tumor;   Astrocytoma;   Astroglioma;   Glioblastoma;   Gliosarcoma
Interventions: Drug: TG02;   Drug: TMZ
13 Not yet recruiting Peptide Targets for Glioblastoma Against Novel Cytomegalovirus Antigens
Conditions: Glioblastoma;   Glioblastoma Multiforme
Interventions: Drug: 5-day TMZ;   Drug: 21-day TMZ;   Biological: PEP-CMV;   Drug: Tetanus-Diphtheria booster;   Drug: Tetanus Pre-Conditioning
14 Recruiting Vigilant ObservatIon of GlIadeL WAfer ImplaNT Registry
Condition: CNS Tumor
Intervention:
15 Recruiting Autologous Cytomegalovirus (CMV)-Specific Cytotoxic T Cells for Glioblastoma (GBM) Patients
Conditions: Glioblastoma;   Gliosarcoma
Interventions: Drug: Temozolomide;   Biological: T Cell Infusion;   Procedure: Surgery;   Behavioral: Phone Calls
16 Recruiting Elevate CLL TN: Study of Obinutuzumab + Chlorambucil, Acalabrutinib (ACP-196) + Obinutuzumab, and Acalabrutinib in Subjects With Previously Untreated CLL
Condition: Chronic Lymphocytic Leukemia
Interventions: Drug: Acalabrutinib;   Drug: Obinutuzumab;   Drug: Chlorambucil
17 Recruiting Methoxyamine and Temozolomide in Treating Patients With Recurrent Glioblastoma
Condition: Adult Brain Glioblastoma
Interventions: Other: Laboratory Biomarker Analysis;   Drug: Methoxyamine;   Drug: Temozolomide
18 Recruiting Phase II Study of Combined Temozolomide and SGT-53 for Treatment of Recurrent Glioblastoma
Condition: GLIOBLASTOMA
Interventions: Genetic: SGT-53;   Drug: Temozolomide
19 Recruiting PV-10 vs Chemotherapy or Oncolytic Viral Therapy for Treatment of Locally Advanced Cutaneous Melanoma
Condition: Melanoma Recurrent
Interventions: Drug: PV-10 (10% rose bengal disodium);   Drug: Dacarbazine, temozolomide or talimogene laherparepvec
20 Recruiting Trabectedin for Recurrent Grade II/III Meningioma
Condition: Recurrent High Grade Meningioma
Interventions: Drug: Trabectedin;   Other: Local standard of care

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Study has passed its completion date and status has not been verified in more than two years.