258 studies found for:    "Alkylating Agents" | updated in the last 30 days
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Rank Status Study
1 Recruiting A Pharmacokinetic Study of Melphalan in Children
Condition: Hematopoietic Stem Cell Transplantation
Intervention: Drug: Melphalan
2 Terminated A Combination of Pazopanib and Carboplatin in Advanced Solid Malignancies
Condition: Cancer, Metastatic
Interventions: Drug: Carboplatin;   Drug: Pazopanib
3 Recruiting Ph 3 Trial of Blinatumomab vs Investigator's Choice of Chemotherapy in Patients With Relapsed or Refractory ALL
Condition: Adult Subjects With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia
Interventions: Drug: Blinatumomab;   Drug: Standard of Care Chemotherapy
4 Recruiting Assessing Fertility Potential in Female Cancer Survivors
Condition: Effects of Chemotherapy
Intervention:
5 Recruiting Rituximab and Combination Chemotherapy With or Without Lenalidomide in Treating Patients With Newly Diagnosed Stage II-IV Diffuse Large B Cell Lymphoma
Conditions: Stage II Contiguous Adult Diffuse Large Cell Lymphoma;   Stage II Non-Contiguous Adult Diffuse Large Cell Lymphoma;   Stage III Adult Diffuse Large Cell Lymphoma;   Stage IV Adult Diffuse Large Cell Lymphoma
Interventions: Drug: Lenalidomide;   Biological: Rituximab;   Drug: Cyclophosphamide;   Drug: Doxorubicin Hydrochloride;   Drug: Vincristine Sulfate;   Drug: Prednisone;   Other: Laboratory Biomarker Analysis
6 Not yet recruiting Methoxyamine and Temozolomide in Treating Patients With Recurrent Glioblastoma
Conditions: Adult Brain Glioblastoma;   Recurrent Adult Brain Neoplasm
Interventions: Drug: Methoxyamine;   Drug: Temozolomide;   Other: Laboratory Biomarker Analysis
7 Active, not recruiting Phase II Trial for Large ER-Negative Breast Cancers
Condition: Malignant Neoplasm of Female Breast
Interventions: Drug: Epirubicin;   Drug: Cyclophosphamide;   Drug: Docetaxel;   Drug: Capecitabine;   Radiation: Radiation Therapy
8 Recruiting A Study Evaluating the Safety and Efficacy of GDC-0199 (ABT-199) Plus Bendamustine + Rituximab (BR) in Comparison With BR or GDC-0199 Plus Rituximab in Patients With Relapsed and Refractory Follicular Non-Hodgkin's Lymphoma
Condition: Follicular Lymphoma
Interventions: Drug: Bendamustine;   Drug: GDC-0199; ABT-199; RO5537382;   Drug: Rituximab [MabThera/Rituxan]
9 Active, not recruiting Open Label Trial to Explore Safety of Combining Afatinib (BIBW 2992) and Radiotherapy With or Without Temozolomide in Newly Diagnosed Glioblastoma Multiform
Condition: Glioblastoma
Interventions: Drug: Temozolomide;   Procedure: Radiotherapy;   Drug: BIBW2992
10 Recruiting S1312, Inotuzumab Ozogamicin and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Leukemia
Conditions: Acute Leukemias of Ambiguous Lineage;   B-cell Adult Acute Lymphoblastic Leukemia;   Philadelphia Chromosome Positive Adult Precursor Acute Lymphoblastic Leukemia;   Recurrent Adult Acute Lymphoblastic Leukemia;   Recurrent Adult Burkitt Lymphoma
Interventions: Drug: cyclophosphamide;   Drug: vincristine sulfate;   Drug: prednisone;   Biological: inotuzumab ozogamicin;   Other: laboratory biomarker analysis
11 Recruiting Study of Weekly Carfilzomib, Cyclophosphamide and Dexamethasone In Newly Diagnosed Multiple Myeloma Patients (wCCyd)
Condition: Multiple Myeloma
Interventions: Drug: Carfilzomib;   Drug: Cyclophosphamide;   Drug: Dexamethasone
12 Active, not recruiting Carboplatin, Paclitaxel, and Temozolomide for Patients With Metastatic Melanoma
Condition: Melanoma
Intervention: Drug: paclitaxel, carboplatin, temozolomide
13 Active, not recruiting Vinorelbine Tartrate and Cyclophosphamide in Combination With Bevacizumab or Temsirolimus in Treating Patients With Recurrent or Refractory Rhabdomyosarcoma
Conditions: Adult Rhabdomyosarcoma;   Childhood Alveolar Rhabdomyosarcoma;   Childhood Anaplastic Rhabdomyosarcoma;   Childhood Mixed Alveolar Rhabdomyosarcoma;   Previously Treated Childhood Rhabdomyosarcoma;   Recurrent Adult Soft Tissue Sarcoma;   Recurrent Childhood Rhabdomyosarcoma
Interventions: Drug: Vinorelbine Tartrate;   Drug: Cyclophosphamide;   Biological: Bevacizumab;   Drug: Temsirolimus;   Other: Laboratory Biomarker Analysis
14 Active, not recruiting Trial of Vorinostat in Combination With Cyclophosphamide, Etoposide, Prednisone and Rituximab for Elderly Patients With Relapsed Diffuse Large B-Cell Lymphoma (DLBCL)
Conditions: Hodgkin's Disease;   Lymphoma
Intervention: Drug: rituximab, cyclophosphamide, etoposide, prednisone, vorinostat and QOL questionnaire, peg-filgrastim or filgrastim
15 Not yet recruiting Retrospective Study to Analyze the Efficacy and Safety of Trabectedin and Pegylated Liposomal Doxorubicin (PLD ) in the Treatment of Patients With Platinum-sensitive Recurrent Ovarian Cancer (ROC), According to SmPC
Condition: Ovarian Epithelial Cancer Recurrent
Intervention: Drug: Trabectedin and Pegylated Liposomal Doxorubicin
16 Active, not recruiting Doxorubicin Hydrochloride, Cyclophosphamide, and Paclitaxel With or Without Bevacizumab in Treating Patients With Lymph Node-Positive or High-Risk, Lymph Node-Negative Breast Cancer
Conditions: Estrogen Receptor Negative;   Estrogen Receptor Positive;   HER2/Neu Negative;   Male Breast Carcinoma;   Stage IA Breast Cancer;   Stage IB Breast Cancer;   Stage IIA Breast Cancer;   Stage IIB Breast Cancer;   Stage IIIA Breast Cancer;   Stage IIIB Breast Cancer;   Stage IIIC Breast Cancer
Interventions: Drug: Doxorubicin Hydrochloride;   Drug: Cyclophosphamide;   Drug: Paclitaxel;   Biological: Bevacizumab;   Other: Placebo;   Other: Laboratory Biomarker Analysis;   Other: Quality-of-Life Assessment
17 Recruiting A Study Comparing the Combination of Trabectedin (YONDELIS) and DOXIL/CAELYX With DOXIL/CAELYX for the Treatment of Advanced-Relapsed Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
Conditions: Ovarian Neoplasms;   Peritoneal Neoplasms;   Fallopian Tube Neoplasms
Interventions: Drug: Trabectedin;   Drug: DOXIL;   Drug: Dexamethasone
18 Active, not recruiting A Study of Trabectedin or Dacarbazine for the Treatment of Patients With Advanced Liposarcoma or Leiomyosarcoma
Condition: Advanced Liposarcoma or Leiomyosarcoma
Interventions: Drug: Trabectedin;   Drug: Dacarbazine
19 Active, not recruiting Radiation Therapy With or Without Temozolomide in Treating Older Patients With Newly Diagnosed Glioblastoma Multiforme
Condition: Brain and Central Nervous System Tumors
Interventions: Drug: temozolomide;   Genetic: DNA methylation analysis;   Procedure: quality-of-life assessment;   Radiation: Radiation
20 Active, not recruiting Chemotherapy With or Without Trastuzumab After Surgery in Treating Women With Invasive Breast Cancer
Conditions: Estrogen Receptor Negative;   Estrogen Receptor Positive;   HER2/Neu Positive;   Progesterone Receptor Negative;   Progesterone Receptor Positive;   Recurrent Breast Carcinoma;   Stage IA Breast Cancer;   Stage IB Breast Cancer;   Stage IIA Breast Cancer;   Stage IIB Breast Cancer;   Stage IIIA Breast Cancer;   Stage IIIC Breast Cancer
Interventions: Drug: Doxorubicin Hydrochloride;   Drug: Docetaxel;   Drug: Cyclophosphamide;   Biological: Trastuzumab;   Drug: Paclitaxel;   Other: Quality-of-Life Assessment;   Other: Laboratory Biomarker Analysis

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Indicates status has not been verified in more than two years