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23 studies found for:    Heart valve disease OR valve stenosis OR regurgitation | Open Studies | NIH, U.S. Fed
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Rank Status Study
1 Recruiting New Techniques to Evaluate Mitral Regurgitation
Condition: Mitral Valve Regurgitation
Intervention:
2 Recruiting A Study Evaluating the Effects of Ataciguat (HMR1766) on Aortic Valve Calcification
Condition: Aortic Valve Stenosis
Interventions: Drug: Ataciguat (HMR1766);   Other: Placebo Comparator: Matching Placebo
3 Recruiting Evaluating the Benefit of Concurrent Tricuspid Valve Repair During Mitral Surgery
Conditions: Mild Tricuspid Regurgitation;   Moderate Tricuspid Regurgitation;   Tricuspid Regurgitation
Interventions: Procedure: TV Annuloplasty;   Procedure: MVS Alone
4 Not yet recruiting Long Term Follow Up for CTSN Mitral Valve Repair Studies
Conditions: Mitral Valve Insufficiency;   Coronary Artery Disease
Interventions: Other: MV Repair;   Other: MV Replacement;   Other: CABG
5 Not yet recruiting NHLBI DIR LAMPOON Study: Intentional Laceration of the Anterior Mitral Leaflet to Prevent Left Ventricular Outflow Tract Obstruction During Transcatheter Mitral Valve Implantation
Condition: Mitral Valve Failure
Interventions: Device: Edwards SAPIEN 3 transcatheter heart valve;   Device: ASHI INTECC Astato XS 20
6 Recruiting Impact of Elastin Mediated Vascular Stiffness on End Organs
Conditions: Williams Syndrome;   Supravalvular Aortic Stenosis;   Cardiovascular Disease
Intervention:
7 Recruiting Cardiovascular Disease Screening
Conditions: Congenital Heart Disease;   Atherosclerosis;   Myocardial Ischemia;   Myocardial Infarction;   Acquired Heart Disease
Intervention:
8 Recruiting Williams Syndrome (WS) and Supravalvular Aortic Stenosis (SVAS) DNA and Tissue Bank
Conditions: Williams Syndrome;   Supravalvular Aortic Stenosis;   Cardiovascular Disease
Intervention:
9 Recruiting Radiation-Free Heart Catheterization Using MRI
Conditions: Aortic Coarctation;   Cardiomyopathy;   Atrial Septal Defect;   Aortic Stenosis;   Post Heart Transplant Catheter Procedure;   Patent Ductus Arteriosus
Interventions: Procedure: MRI guided cardiac catheterization;   Device: Magnetic resonance imaging
10 Recruiting Valsartan for Attenuating Disease Evolution In Early Sarcomeric HCM
Condition: Hypertrophic Cardiomyopathy
Interventions: Drug: Valsartan;   Drug: Placebo
11 Recruiting Hypertrophic Regression With N-Acetylcysteine in HCM
Condition: Hypertrophic Cardiomyopathy
Interventions: Drug: N-acetylcysteine;   Drug: Placebo
12 Recruiting WS-SAVE Study (Williams Syndrome Skin and Vessel Elasticity Study)
Conditions: Williams Syndrome;   Cardiovascular Disease;   Multisystem Developmental Disorder;   Elastin Gene Deletion;   Hypertension
Intervention:
13 Recruiting Defining the Brain Phenotype of Children With Williams Syndrome
Condition: Williams Syndrome
Intervention:
14 Recruiting Exercise in Genetic Cardiovascular Conditions
Conditions: Hypertrophic Cardiomyopathy;   Long QT Syndrome
Intervention:
15 Recruiting Study of Mycobacterial Infections
Conditions: Atypical Mycobacterium Infections;   Cystic Fibrosis;   Job's Syndrome
Intervention:
16 Recruiting Renal Osteodystrophy: An Individual Management Approach
Condition: Kidney Failure, Chronic
Interventions: Drug: Alendronate;   Drug: Teriparatide;   Drug: Cinacalcet
17 Recruiting Study of Alkaptonuria
Condition: Alkaptonuria
Intervention:
18 Recruiting Links Between Inflammation and Cardiometabolic Diseases
Conditions: Diabetes Mellitus;   Cardiovascular Disease;   Healthy Volunteer;   Inflammation
Intervention:
19 Recruiting Long-term Evaluation and Follow-up Care of Patients Treated With Stem Cell Transplants
Conditions: Graft vs Leukemia;   Graft vs Host Disease
Intervention:
20 Recruiting Secondary Pulmonary Hypertension in Adults With Sickle Cell Anemia
Conditions: Pulmonary Hypertension;   Sickle Cell Anemia;   Sickle Cell Disease
Intervention:

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Study has passed its completion date and status has not been verified in more than two years.