21 studies found for:    MAJOR AFFECTIVE DISORDER 5
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Rank Status Study
1 Recruiting Examination of Glutamate and mGluR5 in Psychiatric Disorders
Conditions: Major Depressive Disorder;   Post-Traumatic Stress Disorder;   Bipolar Disorder
Interventions: Behavioral: Cognitive Testing;   Other: MRI;   Radiation: PET
2 Withdrawn Imaging Serotonin 5HT1A Receptors in Patients With Major Depressive Disorder
Conditions: Major Depression;   Unipolar Depression;   Depression;   Anxiety Disorder
Intervention: Other: Antidepressant (SSRI)
3 Recruiting A Study of ALKS 5461 for the Treatment of Major Depressive Disorder (MDD) - FORWARD-5 Study
Condition: Major Depressive Disorder
Interventions: Drug: ALKS 5461;   Drug: Placebo
4 Recruiting Vortioxetine, 5, 10, and 20 mg, Relapse Prevention Study in Adults With Major Depressive Disorder
Condition: Major Depressive Disorder
Interventions: Drug: Vortioxetine;   Drug: Placebo
5 Completed Sensitivity of Short and Long Allele Carriers of the 5-HTTLPR to Environmental Threat Post Hydrocortisone Administration
Conditions: Major Depressive Disorder;   Anxiety Disorders
Intervention: Drug: Hydrocortisone
6 Active, not recruiting rTMS for PTSD Comorbid With Major Depressive Disorder
Conditions: Posttraumatic Stress Disorder;   Major Depressive Disorder;   Transcranial Magnetic Stimulation, Repetitive
Intervention: Device: Transcranial Magnetic Stimulation
7 Completed 5-hydroxytryptophan and Creatine for Treatment Resistant Depression Associated With Hypoxia in Females
Condition: Major Depressive Disorder
Intervention: Drug: 5-hydroxytryptophan and Creatine monohydrate
8 Completed PET Imaging of mGLuR5 With Drug Challenge
Conditions: Major Depressive Disorder;   Post-Traumatic Stress Disorder (PTSD)
Intervention: Drug: Ketamine
9 Completed
Has Results
Open-label Safety Extension Study of 5 and 10 mg of Vortioxetine (Lu AA21004) in Long-term Treatment of Major Depressive Disorder in Adults
Condition: Major Depressive Disorder
Intervention: Drug: Vortioxetine (Lu AA21004)
10 Completed
Has Results
Open-label Safety Extension Study of 2.5, 5 and 10 mg of Vortioxetine (Lu AA21004) in Long-term Treatment of Major Depressive Disorder in Adults
Condition: Major Depressive Disorder
Intervention: Drug: Vortioxetine (Lu AA21004)
11 Completed
Has Results
Randomised Placebo-controlled Duloxetine-referenced Efficacy and Safety Study of 2.5, 5 and 10 mg of Vortioxetine (Lu AA21004) in Acute Treatment of Major Depressive Disorder
Condition: Major Depressive Disorder
Interventions: Drug: Placebo;   Drug: Vortioxetine (Lu AA21004);   Drug: Duloxetine
12 Completed
Has Results
Randomised Placebo-controlled Venlafaxine-referenced Study of Efficacy and Safety of 5 and 10 mg of Vortioxetine (Lu AA21004) in Acute Treatment of Major Depressive Disorder in Adults
Condition: Major Depressive Disorder
Interventions: Drug: Placebo;   Drug: Vortioxetine (Lu AA21004);   Drug: Venlafaxine XL
13 Not yet recruiting Treatment Outcome in Major Depressive Disorder
Condition: Major Depressive Disorder
Interventions: Drug: Escitalopram;   Drug: Duloxetine
14 Completed Effect of Physical Activity on Depressive Symptoms With a 5 Month Follow-up
Condition: Major Depressive Disorder
Intervention: Other: Physical activity program
15 Completed
Has Results
Randomised Placebo-controlled Duloxetine-referenced Study of Efficacy and Safety of 5 mg of Vortioxetine (Lu AA21004) in Acute Treatment of Major Depressive Disorder in Elderly Patients
Condition: Major Depressive Disorder
Interventions: Drug: Placebo;   Drug: Vortioxetine (Lu AA21004);   Drug: Duloxetine
16 Completed Flexible Dose Titration Add-on Study to Treat Major Depressive Disorder
Condition: Major Depressive Disorder
Intervention: Drug: Mecamylamine
17 Completed An Investigation of the Antidepressant Efficacy of the 5-HT2A Antagonist, M100907, in Combination With Citalopram in Treatment Resistant Depression
Condition: Depressive Disorder
Intervention: Drug: MDL100.907
18 Completed PET Whole Body Distribution Studies Using [11C]CUMI
Conditions: Depression;   Major Depression;   Unipolar Depression;   Anxiety Disorder;   Anxiety Disorders
Intervention:
19 Completed Brain Chemical Receptor Effects in Patients With Panic Disorder and Post-Traumatic Stress Disorder
Conditions: Panic Disorder;   Posttraumatic Stress Disorder;   Major Depressive Disorder
Intervention:
20 Unknown  The Effects of Vilazodone on Glutamate in the Anterior Cingulate Cortex in Anxious Unipolar Depressives
Conditions: Major Depressive Disorder;   Anxiety;   Comorbidity
Interventions: Drug: Vilazodone;   Drug: Citalopram

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Indicates status has not been verified in more than two years