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49 studies found for:    FAMILIAL ADENOMATOUS POLYPOSIS 1
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Rank Status Study
1 Completed
Has Results
A Clinical Trial of COX and EGFR Inhibition in Familial Polyposis Patients
Condition: Adenomatous Polyposis Coli
Interventions: Drug: Erlotinib;   Drug: Sulindac;   Drug: Placebo A;   Drug: Placebo B
2 Recruiting Small Bowel Endoscopic Evaluation in Familial Adenomatous Polyposis (FAP)
Condition: Familial Adenomatous Polyposis
Interventions: Procedure: Duodenoscopy and enteroscopy;   Genetic: Molecular analysis.
3 Completed
Has Results
Lyophilized Black Raspberries in Adults With Familial Adenomatous Polyposis (FAP)
Condition: Familial Adenomatous Polyposis
Interventions: Drug: Black raspberry (BRB) Slurry;   Drug: Black Raspberry (BRB) Suppositories;   Drug: Black Raspberry (BRB) Placebo Slurry
4 Withdrawn Use of Curcumin in the Lower Gastrointestinal Tract in Familial Adenomatous Polyposis Patients
Condition: Familial Adenomatous Polyposis
Intervention: Drug: curcumin
5 Active, not recruiting Trial of Eflornithine Plus Sulindac in Patients With Familial Adenomatous Polyposis (FAP)
Condition: Familial Adenomatous Polyposis
Interventions: Drug: Eflornithine plus Sulindac;   Drug: Eflornithine and Placebo;   Drug: Sulindac and Placebo
6 Unknown  Erythromycin Treatment for Readthrough of APC Gene Stop Codon Mutations in Familial Adenomatous Polyposis
Condition: FAP-Familial Adenomatous Polyposis
Intervention: Drug: Erythromycin
7 Recruiting Non-Surgical Management of Attenuated and Deleterious (Classical) Familial Adenomatous Polyposis: A Long-term Surveillance Program
Conditions: Attenuated Familial Adenomatous Polyposis;   Deleterious Familial Adenomatous Polyposis
Intervention: Other: Chart Review
8 Completed Molecular Fluorescence Endoscopy in Patients With Familial Adenomatous Polyposis, Using Bevacizumab-IRDye800CW
Condition: Adenomatous Polyposis Coli
Interventions: Drug: Bevacizumab-IRDye800CW;   Device: Near infrared fluorescence endoscopy platform
9 Not yet recruiting Erythromycin Treatment for Readthrough of APC Gene Stop Codon Mutation in Familial Adenomatous Polyposis-minors' Adjusted Version
Condition: FAP-Familial Adenomatous Polyposis
Intervention: Drug: Erythromycin
10 Active, not recruiting Use of Curcumin for Treatment of Intestinal Adenomas in Familial Adenomatous Polyposis (FAP)
Condition: Familial Adenomatous Polyposis
Interventions: Drug: Calcumin (Curcumin);   Other: Risk Factor Questionnaire;   Other: Blood samples;   Other: Biopsies (Sigmoidoscopy);   Other: Biopsies (Upper endoscopy)
11 Terminated
Has Results
Observational Familial Adenomatous Polyposis Registry Study In Patients Receiving Celecoxib Compared to Control Patients
Condition: Familial Adenomatous Polyposis (FAP)
Interventions: Drug: Celecoxib;   Other: Routine Medical Care
12 Terminated
Has Results
Trial In Pediatric Patients With Familial Adenomatous Polyposis (FAP)
Condition: Adenomatous Polyposis Coli
Interventions: Drug: Celecoxib;   Drug: Placebo
13 Terminated A Study of Rofecoxib in Familial Adenomatous Polyposis (FAP)
Condition: Adenomatous Polyposis Coli
Interventions: Drug: MK0966; rofecoxib / Duration of Treatment: 24 weeks;   Drug: Comparator: placebo / Duration of Treatment: 24 weeks
14 Recruiting Sirolimus and Familial Adenomatous Polyposis (FAP)
Condition: Adenomatous Polyposis Coli
Intervention: Drug: Sirolimus
15 Completed Curcumin in Treating Patients With Familial Adenomatous Polyposis
Condition: Familial Adenomatous Polyposis
Interventions: Drug: Curcumin;   Other: Laboratory Biomarker Analysis;   Other: Placebo
16 Unknown  The Chemopreventive Effect of Metformin in Patients With Familial Adenomatous Polyposis: Double Blinded Randomized Controlled Study
Condition: Familial Adenomatous Polyposis
Intervention: Drug: metformin
17 Withdrawn A Trial of Low Dose Sulindac Combined With Eflornithine in Patients With Familial Adenomatous Polyposis (FAP)
Condition: Familial Adenomatous Polyposis
Interventions: Drug: Eflornithine plus Sulindac;   Drug: Eflornithine plus Placebo;   Drug: Sulindac plus Placebo
18 Not yet recruiting Erlotinib Hydrochloride in Reducing Duodenal Polyp Burden in Patients With Familial Adenomatous Polyposis at Risk of Developing Colon Cancer
Conditions: Attenuated Familial Adenomatous Polyposis;   Familial Adenomatous Polyposis
Interventions: Drug: Erlotinib Hydrochloride;   Other: Laboratory Biomarker Analysis
19 Unknown  Influence of Sulindac and Probiotics on the Development of Pouch Adenomas in Patients With Familial Adenomatous Polyposis
Condition: Adenomatous Polyposis Coli
Interventions: Drug: Sulindac (drug);   Drug: VSL#3 (probiotic);   Drug: Inulin (probiotic)
20 Unknown  Ursodeoxycholic Acid in the Treatment of Duodenal Adenomas in Familial Adenomatous Polyposis (FAP) Patients
Condition: Adenomatous Polyposis Coli, Familial
Interventions: Drug: Ursodeoxycholic acid;   Drug: Placebo

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Study has passed its completion date and status has not been verified in more than two years.