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24 studies found for:    CROUZON SYNDROME
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Rank Status Study
1 Terminated Phase I, Dose-escalation Trial of BAY1187982 in Subjects With Advanced Solid Tumors Known to Express Fibroblast Growth Factor Receptor 2 (FGFR2)
Condition: Medical Oncology
Intervention: Drug: BAY1187982
2 Recruiting A Phase II, Single Arm Study of BGJ398 in Patients With Advanced Cholangiocarcinoma
Condition: Advanced Cholangiocarcinoma
Intervention: Drug: BGJ398
3 Active, not recruiting Phase 1/2 Study of ARQ 087 in Adult Subjects With Advanced Solid Tumors With FGFR Genetic Alterations
Condition: Solid Tumor
Intervention: Drug: ARQ 087
4 Recruiting Dovitinib for Gastric Cancer With FGFR2 Amplification
Condition: Gastric Cancer
Intervention: Drug: Dovitinib
5 Unknown  Study of Resting and Exercising Body Functioning in Freeman-Sheldon Syndrome and Related Conditions
Conditions: Arthrogryposis;   Craniofacial Abnormalities
Interventions: Other: Lactate, Glucose, and Adenosine Triphosphate Blood Levels;   Procedure: Physiological Stress Test;   Other: Functional Enquiry Form;   Other: Strength, Joint ROM, Girth and Length Measurements;   Other: Study Physical Examination;   Other: Observational Gait Analysis;   Other: Mental Health Interview
6 Not yet recruiting Pan FGFR Kinase Inhibitor BGJ398 in Treating Patients With FGFR1-3 Translocated, Mutated, or Amplified Recurrent Head and Neck Cancer
Conditions: FGFR Gene Amplification;   FGFR1 Gene Amplification;   FGFR2 Gene Amplification;   FGFR2 Gene Mutation;   FGFR3 Gene Mutation;   Head and Neck Squamous Cell Carcinoma;   Human Papillomavirus Infection;   Recurrent Head and Neck Carcinoma;   Recurrent Nasopharynx Carcinoma;   Recurrent Oropharyngeal Squamous Cell Carcinoma
Interventions: Other: Laboratory Biomarker Analysis;   Drug: pan FGFR Kinase Inhibitor BGJ398
7 Recruiting Survey Study and Records Review of Treatment Outcomes in Freeman-Sheldon Syndrome
Conditions: Freeman-Sheldon Syndrome;   Arthrogryposis Distal Type 2A;   Whistling Face Syndrome;   Craniocarpotarsal Dysplasia;   Craniocarpotarsal Dystrophy;   Freeman-Sheldon Syndrome Variant;   Sheldon-Hall Syndrome;   Arthrogryposis Distal Type 2B;   Gordon Syndrome;   Arthrogryposis Distal Type 3;   Arthrogryposis Distal Type 1;   Arthrogryposis, Distal, Type 1A;   Arthrogryposis Distal Type 1B;   Arthrogryposis, Distal;   Craniofacial Abnormalities;   Arthrogryposis
Interventions: Other: PTSD Checklist-Civilian (PCL-C);   Other: Modified Flanagan Quality of Life Scale;   Other: Center for Epidemiologic Studies Depression Scale (CES-D);   Other: Functional Enquiry (or Review of Systems) Form;   Other: Study of Therapeutic Outcomes and Practices in Freeman-Sheldon Syndrome (STOP-FSS) Questionnaire;   Other: FSRG Semi-Structured Quality of Life Interview (FSRG SSQLI);   Other: Medical Records Review
8 Terminated Study of Quality of Life in Freeman-Sheldon Syndrome and Related Conditions
Conditions: Arthrogryposis;   Craniofacial Abnormalities;   Posttraumatic Stress Disorder;   Depressive Disorder
Interventions: Other: PTSD Checklist-Specific;   Other: Modified Flanagan Quality of Life Scale;   Other: Center for Epidemiologic Studies Depression Scale;   Other: Functional Enquiry Form;   Other: Strength, Joint ROM, Girth and Length Measurements;   Other: Study Physical Examination;   Other: PTSD, Depression, and FSS-Focused Examination;   Other: Freeman-Sheldon Specific Quality of Life Survey;   Other: Lactate, Glucose, and Adenosine Triphosphate Blood Levels
9 Recruiting Genetic and Functional Analysis of Craniometaphyseal Dysplasia (CMD)
Condition: Craniometaphyseal Dysplasia
Intervention:
10 Not yet recruiting Role of Mesenchymal Stem Cells in Fat Grafting
Conditions: Romberg's Disease;   Craniofacial Microsomia;   Lipodystrophy;   Mixed Connective Tissue Disease
Interventions: Procedure: Fat graft enriched with ex vivo expanded stem cells;   Procedure: Fat graft not enriched with ex vivo expanded stem cells
11 Completed Clinical Trial of Fat Grafts Supplemented With Adipose-derived Regenerative Cells
Condition: Craniofacial Microsomia
Interventions: Procedure: Supplementation of ADRC;   Procedure: Without supplementation of ADRC
12 Recruiting Natural History of Craniofacial Anomalies and Developmental Growth Variants
Conditions: Prognathism;   Dentofacial Deformities;   Hemifacial Macrosomia;   Craniofacial Microsomia
Intervention:
13 Recruiting Craniofacial Microsomia: Longitudinal Outcomes in Children Pre-Kindergarten (CLOCK)
Conditions: Craniofacial Microsomia;   Hemifacial Microsomia;   Oculo-Auriculo-Vertebral-Syndrome;   Goldenhar Syndrome;   Microtia
Intervention:
14 Recruiting Cholesterol and Antioxidant Treatment in Patients With Smith-Lemli-Opitz Syndrome (SLOS)
Conditions: Smith-Lemli-Opitz Syndrome;   Cone-Rod Dystrophy;   Hearing Loss
Interventions: Drug: Antioxidants;   Drug: Cholesterol
15 Unknown  SLOS: The Effect of Simvastatin in Patients Receiving Cholesterol Supplementation
Condition: Smith-Lemli-Opitz Syndrome
Interventions: Drug: Simvastatin;   Dietary Supplement: Lactose
16 Withdrawn A Long-Term Study of Cholesterol Supplements for Smith-Lemli-Opitz Syndrome
Condition: Smith-Lemi-Opitz Syndrome
Intervention:
17 Unknown  Sterol and Isoprenoid Disease Research Consortium: Smith-Lemli-Opitz Syndrome
Condition: Smith-Lemli-Opitz Syndrome
Intervention: Dietary Supplement: Cholesterol supplementation
18 Completed Treatment of the Cholesterol Defect in Smith-Lemli-Opitz Syndrome
Condition: Smith-Lemli-Opitz Syndrome
Intervention: Drug: crystalline cholesterol oil-based suspension
19 Completed
Has Results
Short-term Behavioral Effects of Cholesterol Therapy in Smith-Lemli-Opitz Syndrome
Condition: Smith-Lemli-Opitz Syndrome
Interventions: Dietary Supplement: Egg yolk preparation with cholesterol;   Dietary Supplement: Egg substitute, without cholesterol
20 Completed Prenatal Screening For Smith-Lemli-Opitz Syndrome
Conditions: Smith-Lemli-Opitz Syndrome;   Pregnancy
Intervention:

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Study has passed its completion date and status has not been verified in more than two years.