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413 studies found for:    Amyloidosis
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Rank Status Study
1 Recruiting Carpal Tunnel Syndrome and Amyloid Cardiomyopathy
Conditions: Amyloidosis;   Cardiomyopathy;   Transthyretin Amyloidosis;   Senile Systemic Amyloidosis;   Carpal Tunnel Syndrome
Intervention:
2 Active, not recruiting Prevalence of Transthyretin Amyloidosis in Hypertrophic Cardiomyopathy
Conditions: Cardiac Amyloidosis;   Amyloidosis in Transthyretin (TTR);   Hypertrophic Cardiomyopathy (HCM)
Intervention:
3 Completed Burden of Disease Study In Patients With Transthyretin Familial Amyloidosis Polyneuropathy (TTR-FAP) orTransthyretin Cardiomyopathy (TTR-CM) And Caregivers
Conditions: Transthyretin Familial Amyloidosis Polyneuropathy (TTR-FAP);   Transthyretin Cardiomyopathy (TTR-CM);   Familial Amyloid Cardiomyopathy;   Senile Systemic Amyloidosis (SSA)
Intervention: Other: No drug
4 Active, not recruiting Efficacy and Safety of IONIS-TTR Rx in Familial Amyloid Polyneuropathy
Conditions: FAP;   Familial Amyloid Polyneuropathy;   TTR;   Transthyretin;   Amyloidosis
Interventions: Drug: IONIS-TTR Rx;   Drug: Placebo
5 Recruiting Transthyretin-Associated Amyloidoses Outcome Survey (THAOS)
Conditions: Transthyretin Mutations;   Transthyretin Amyloidosis
Intervention: Other: None. Observational Study.
6 Enrolling by invitation Open-Label Extension Assessing Long Term Safety and Efficacy of IONIS-TTR Rx in Familial Amyloid Polyneuropathy (FAP)
Conditions: FAP;   Familial Amyloid Polyneuropathy;   TTR;   Transthyretin;   Amyloidosis
Intervention: Drug: IONIS-TTR Rx
7 Completed The Effect of Diflunisal on Familial Transthyretin Amyloidosis
Condition: Amyloidosis
Intervention: Drug: Diflunisal
8 Completed The Effect of Diflunisal on Familial Amyloidosis
Conditions: Familial Amyloid Polyneuropathy;   Familial Amyloidosis
Interventions: Drug: diflunisal;   Other: placebo
9 Recruiting Prevalence and Post-surgical Outcomes of CARdiac Wild-type TransthyrEtin amyloidoSIs in Elderly Patients With Aortic steNosis Referred for Valvular Replacement.
Conditions: Heart Disease;   Aging;   Amyloidosis;   Aortic Valve Stenosis
Intervention: Other: a basal LV septum biopsy
10 Active, not recruiting The Study of an Investigational Drug, Revusiran (ALN-TTRSC), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis in Patients Whose Disease Has Continued to Worsen Following Liver Transplant
Conditions: Transthyretin (TTR)-Mediated Amyloidosis;   Familial Amyloidotic Polyneuropathy (FAP);   ATTR Amyloidosis;   Familial Amyloid Neuropathies
Intervention: Drug: Revusiran (ALN-TTRSC)
11 Completed Safety and Efficacy Study of Doxycycline/UrsoDeoxyCholicAcid on Disease Progression in ATTR Amyloidosis
Conditions: Transthyretin Amyloidosis;   Cardiomyopathy
Interventions: Drug: Doxycycline;   Drug: Ursodeoxycholic acid
12 Completed Safety, Efficacy and Pharmacokinetics of Doxycycline Plus Tauroursodeoxycholic Acid in Transthyretin Amyloidosis
Condition: Transthyretin Amyloidosis
Intervention: Drug: Doxycycline + Tauroursodeoxycholic acid
13 Active, not recruiting APOLLO: The Study of an Investigational Drug, Patisiran (ALN-TTR02), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis
Conditions: TTR-mediated Amyloidosis;   Amyloidosis, Hereditary;   Amyloid Neuropathies, Familial;   Familial Amyloid Polyneuropathies;   Amyloid Neuropathies;   Amyloidosis, Hereditary, Transthyretin-Related
Interventions: Drug: patisiran (ALN-TTR02);   Drug: Sterile Normal Saline (0.9% NaCl)
14 Completed
Has Results
The Effects of Fx-1006A on Transthyretin Stabilization and Clinical Outcome Measures in Patients With Non-V30M Transthyretin Amyloidosis
Condition: Transthyretin-associated Amyloidosis With Polyneuropathy
Intervention: Drug: Fx-1006A
15 Active, not recruiting Quality of Life (QOL) Registry for Patients With AL Amyloidosis
Conditions: AL Amyloidosis;   Amyloidosis
Intervention: Other: non-interventional
16 Active, not recruiting Tolerability and Efficacy of a Combination of Doxycycline and TUDCA in Patients With Transthyretin Amyloid Cardiomyopathy
Conditions: Amyloidosis; Heart (Manifestation);   Senile Cardiac Amyloidosis
Intervention: Drug: Tauroursodeoxycholic Acid and Doxycycline
17 Recruiting Minimal Residual Disease as a Possible Predictive Factor for Relapse in Patients With AL Amyloidosis
Conditions: Amyloidosis;   Primary Amyloidosis
Intervention:
18 Active, not recruiting Safety and Effect of Doxycycline in Patients With Amyloidosis
Condition: Amyloidosis
Intervention: Drug: Doxycycline 100 mg po bid x 12 months
19 Active, not recruiting A Safety Study of Carfilzomib in Patients With Previously-Treated Systemic Light Chain Amyloidosis
Conditions: Amyloidosis;   Systemic Light Chain Amyloidosis
Interventions: Drug: Carfilzomib;   Drug: Dexamethasone
20 Active, not recruiting Bortezomib and Dexamethasone Followed by High-Dose Melphalan and Stem Cell Transplantation for Primary (AL) Amyloidosis
Condition: Amyloidosis
Intervention: Drug: Bortezomib (Velcade) and Dexamethasone

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