63 studies found for:    ALPHA-1-ANTITRYPSIN DEFICIENCY
Show Display Options
Rank Status Study
21 Completed
Has Results
Comparison of Pharmacokinetic, Safety, Tolerability of Alpha-1 MP and Prolastin In Alpha1-antitrypsin Deficient Adults
Condition: Alpha 1-Antitrypsin Deficiency
Interventions: Drug: Alpha-1 MP;   Drug: alpha-1 proteinase inhibitor (human)
22 Completed
Has Results
Alpha-1-Antitrypsin (AAT) To Treat Emphysema In AAT-Deficient Patients (EXACTLE)
Condition: Alpha 1-Antitrypsin Deficiency
Interventions: Drug: Alpha1-Proteinase Inhibitor (Human);   Drug: Albumin (Human) 20%, United States Pharmacopeia (USP)
23 Recruiting Lung Disease and Its Affect on the Work of White Blood Cells in the Lungs
Conditions: Alpha-1 Antitrypsin Deficiency;   AAT Deficiency;   AATD;   Cystic Fibrosis (CF)
Interventions: Procedure: History and physical exam.;   Procedure: Blood draw.;   Procedure: Pulmonary function testing.;   Drug: Albuterol inhaler.
24 Completed Alpha1-antitrypsin Deficiency Registry
Conditions: Lung Diseases;   Emphysema;   Alpha-1 Antitrypsin Deficiency;   Chronic Obstructive Pulmonary Disease
Intervention:
25 Completed
Has Results
Extension Study of Zemaira® i.v. Administration in Subjects With Emphysema Due to alpha1-proteinase Inhibitor Deficiency.
Conditions: Emphysema;   Alpha 1-proteinase Inhibitor Deficiency
Intervention: Biological: Alpha1- proteinase inhibitor [human]
26 Recruiting Lung Volume Reduction Coils for Emphysema in Alpha-1 Antitrypsin Deficiency
Conditions: Alpha-1-Antitrypsin Deficiency;   Chronic Obstructive Lung Disease;   Emphysema
Intervention: Device: Lung Volume Reduction Coil (PneumrX Inc.)
27 Completed Experimental Gene Transfer Procedure to Treat Alpha 1-Antitrypsin Deficiency
Condition: Alpha 1-Antitrypsin Deficiency
Intervention: Biological: rAAV1-CB-hAAT
28 Active, not recruiting Experimental Gene Transfer Procedure to Treat Alpha 1-Antitrypsin Deficiency
Condition: Alpha 1-Antitrypsin Deficiency
Intervention: Genetic: rAAV2-CB-hAAT Gene Vector
29 Completed A Study to Assess Safety and PK of Liquid Alpha1-Proteinase Inhibitor (Human) in Treating Alpha1-Antitrypsin Deficiency
Condition: Alpha1-antitrypsin Deficiency
Interventions: Biological: Liquid Alpha1-PI;   Biological: Prolastin-C
30 Completed
Has Results
Zemaira in Subjects With Emphysema Due to Alpha1-Proteinase Inhibitor Deficiency
Conditions: Alpha1-proteinase Inhibitor Deficiency;   Emphysema
Interventions: Biological: Alpha1-proteinase inhibitor;   Other: Placebo
31 Completed
Has Results
Pharmacokinetic Study of ARALAST (Human Alpha1- PI)
Condition: Alpha 1-Antitrypsin Deficiency
Interventions: Biological: Dose of 60 mg/kg Fraction IV-1 Alpha1-Proteinase Inhibitor;   Biological: Dose of 60 mg/kg alpha1-proteinase inhibitor
32 Completed Effect of Double Dose of Alpha 1-antitrypsin Augmentation Therapy on Lung Inflammation.
Condition: Alpha 1 Antitrypsin Deficiency
Intervention: Drug: Alpha-1 Antitrypsin (human)
33 Recruiting Environment Effect on Six-Minute Walk Test Performance
Conditions: Chronic Obstructive Pulmonary Disease;   Alpha-1 Antitrypsin Deficiency
Interventions: Other: six-minute walk study indoors;   Other: six-minute walk study outdoors
34 Completed Phase II, Safety and ELF Study of "Kamada-API for Inhalation"
Condition: Alpha-1 Antitrypsin Deficiency
Interventions: Biological: Kamada-API for Inhalation, 80mg;   Drug: Placebo;   Biological: Kamada-API for Inhalation, 160mg
35 Completed 4-PBA: Will it Increase the Level of Alpha 1-Antitrypsin(AAT) in Persons With AAT Deficiency?
Condition: Alpha 1-Antitrypsin Deficiency
Intervention: Drug: 4-PBA
36 Recruiting Ph 3/4 GLASSIA Safety, Immunogenicity, and Bronchoalveolar Lavage Study
Condition: Alpha1-antitrypsin Deficiency
Intervention: Biological: GLASSIA
37 Recruiting Stage 1 Study of ARALAST NP and GLASSIA in A1PI
Conditions: Chronic Obstructive Pulmonary Disease;   Alpha1-antitrypsin Deficiency
Interventions: Biological: ARALAST NP 60 mg/kg;   Biological: ARALAST NP 120 mg/kg;   Biological: GLASSIA 60 mg/kg;   Biological: GLASSIA 120 mg/kg;   Biological: Human Albumin 2%
38 Completed
Has Results
Efficacy and Safety Study of Augmentation Therapy With ARALAST Fraction IV-1 (Human Alpha 1 - Proteinase Inhibitor)
Condition: Alpha 1-Antitrypsin Deficiency
Intervention: Biological: Alpha1-Proteinase Inhibitor
39 Recruiting Alpha-1 Carrier Genomics Study
Conditions: Alpha-1 Antitrypsin Deficiency;   Emphysema;   COPD;   Smoking
Intervention: Genetic: Genetic Sequencing
40 Recruiting Alpha-1 Coded Testing(ACT) Study
Condition: Alpha-1 Antitrypsin Deficiency
Intervention: Procedure: Alpha-1 Antitrypsin Genotype

First Page    Show previous page of results Previous Page (1-20) Studies Shown (21-40) Next Page (41-60) Show next page of results    Last Page
Indicates status has not been verified in more than two years