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49 studies found for:    "tuberous sclerosis"

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Rank Status Study
1 Unknown † Tuberous Sclerosis Complex Natural History Study: Renal Manifestations
Condition: Tuberous Sclerosis Complex
Intervention:
2 Completed
Has Results 		Everolimus (RAD001) Therapy of Giant Cell Astrocytoma in Patients With Tuberous Sclerosis Complex
Conditions: Tuberous Sclerosis;   Subependymal Giant Cell Astrocytoma
Intervention: Drug: Everolimus
3 Recruiting Study of Skin Tumors in Tuberous Sclerosis
Conditions: Hereditary Neoplastic Syndrome;   Tuberous Sclerosis
Intervention:
4 Recruiting Treatment of Renal Angiomyolipomas in Tuberous Sclerosis by Beta-blockers
Conditions: Renal Angiomyolipomas;   Tuberous Sclerosis
Intervention: Drug: Propranolol
5 Recruiting Genetic Heterogeneity and Genotype-phenotype Correlation of Children and Adults With Tuberous Sclerosis Complex
Conditions: Sclerosis Tuberosa;   Tuberous Sclerosis Complex;   Cerebral Sclerosis;   Nervous System Disorders
Intervention:
6 Unknown † Trial of Efficacy and Safety of Sirolimus in Tuberous Sclerosis and LAM
Conditions: Tuberous Sclerosis;   Lymphangioleiomyomatosis
Intervention: Drug: sirolimus
7 Completed Rapamycin Therapy for Patients With Tuberous Sclerosis Complex and Sporadic LAM
Conditions: Tuberous Sclerosis;   Lymphangioleiomyomatosis
Intervention: Drug: Rapamycin, sirolimus
8 Recruiting Autism Spectrum Disorder (ASD) and Intellectual Disability (ID) Determinants in Tuberous Sclerosis Complex (TSC)
Conditions: Tuberous Sclerosis;   Autism Disorder;   Intellectual Disability
Intervention:
9 Completed Topical Rapamycin Therapy to Alleviate Cutaneous Manifestations of Tuberous Sclerosis Complex (TSC) and Neurofibromatosis I (NF1)
Conditions: Tuberous Sclerosis;   Neurofibromatoses;   Angiofibroma;   Neurofibroma
Interventions: Drug: Skincerity;   Drug: Skincerity plus sirolimus/rapamycin;   Drug: Skinercity plus sirolimus/rapamycin
10 Not yet recruiting Long-term Trial of Topical Sirolimus to Angiofibroma in Patient With Tuberous Sclerosis Complex
Conditions: Tuberous Sclerosis;   Angiofibroma;   Hypomelanotic Macule;   Plaque
Intervention: Drug: NPC-12G gel
11 Completed
Has Results 		Everolimus (RAD001) Therapy for Epilepsy in Patients With Tuberous Sclerosis Complex (TSC)
Conditions: Epilepsy;   Tuberous Sclerosis Complex
Intervention: Drug: Everolimus
12 Completed Trial of RAD001 and Neurocognition in Tuberous Sclerosis Complex (TSC)
Condition: Tuberous Sclerosis Complex
Intervention: Drug: RAD001
13 Recruiting A Study of Everolimus in the Treatment of Neurocognitive Problems in Tuberous Sclerosis
Condition: Tuberous Sclerosis
Interventions: Drug: Placebo;   Drug: Everolimus (RAD001)
14 Recruiting Early Biomarkers of Autism in Infants With Tuberous Sclerosis Complex (TSC)
Condition: Tuberous Sclerosis Complex
Intervention:
15 Completed Long Term Follow Up for RAD001 Therapy of Angiomyolipomata in Patients With Tuberous Sclerosis (TSC) and Sporadic Lymphangioleiomyomatosis (LAM)
Conditions: Tuberous Sclerosis;   Angiolipoma
Intervention: Drug: everolimus (RAD001)
16 Not yet recruiting Phase III Trial of Topical Formulation of Sirolimus to Skin Lesions in Patients With Tuberous Sclerosis Complex (TSC)
Conditions: Tuberous Sclerosis;   Angiofibroma;   Hypomelanotic Macule;   Plaque
Interventions: Drug: NPC-12G gel;   Drug: Placebo gel
17 Completed
Has Results 		Efficacy and Safety of Everolimus (RAD001) in Patients of All Ages With Subependymal Giant Cell Astrocytoma Associated With Tuberous Sclerosis Complex (TSC)(EXIST-1)
Conditions: Tuberous Sclerosis;   Subependymal Giant Cell Astrocytoma
Interventions: Drug: Everolimus;   Drug: Placebo
18 Recruiting Efficacy of RAD001/Everolimus in Autism and NeuroPsychological Deficits in Children With Tuberous Sclerosis Complex
Conditions: Tuberous Sclerosis Complex;   TSC Related Cognitive Disability;   TSC Related Autism;   TSC Related Learning Problems
Interventions: Drug: Everolimus;   Drug: Placebo
19 Recruiting Long-term, Prospective Study Evaluating Clinical and Molecular Biomarkers of Epileptogenesis in a Genetic Model of Epilepsy - Tuberous Sclerosis Complex
Conditions: TSC;   Tuberous Sclerosis Complex;   Epilepsy
Intervention: Device: epilepsy early diagnosis protocol
20 Completed
Has Results 		Efficacy and Safety of RAD001 in Patients Aged 18 and Over With Angiomyolipoma Associated With Either Tuberous Sclerosis Complex (TSC) or Sporadic Lymphangioleiomyomatosis (LAM)
Conditions: Tuberous Sclerosis Complex (TSC);   Lymphangioleiomyomatosis (LAM)
Interventions: Drug: Everolimus (RAD001);   Drug: Placebo
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† Indicates status has not been verified in more than two years