64 studies found for:    "spinal muscular atrophy"
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21 Completed An Open-label Safety, Tolerability, and Dose-range Finding Study of ISIS SMNRx in Patients With Spinal Muscular Atrophy
Condition: Spinal Muscular Atrophy
Intervention: Drug: ISIS-SMNRx
22 Recruiting A Study to Assess the Efficacy and Safety of ISIS-SMN Rx in Patients With Later-onset Spinal Muscular Atrophy
Condition: Spinal Muscular Atrophy
Interventions: Drug: ISIS-SMN Rx;   Procedure: Sham procedure
23 Recruiting Safety and Efficacy Study of Pyridostigmine on Patients With Spinal Muscular Atrophy Type 3
Condition: Spinal Muscular Atrophy Type 3
Intervention: Drug: Pyridostigmine Bromide
24 Completed An Open-label Safety, Tolerability and Dose-range Finding Study of Multiple Doses of ISIS SMNRx in Patient With Spinal Muscular Atrophy
Condition: Spinal Muscular Atrophy
Intervention: Drug: ISIS-SMNRx
25 Completed An Open-label Safety and Tolerability Study of ISIS SMNRx in Patients With Spinal Muscular Atrophy Who Previously Participated in ISIS 396443-CS1
Condition: Spinal Muscular Atrophy
Intervention: Drug: ISIS-SMNRx
26 Active, not recruiting An Open-label Safety and Tolerability Study of ISIS SMNRx in Patients With Spinal Muscular Atrophy Who Previously Participated in ISIS SMNRx-CS2 or ISIS SMNRx-CS10
Condition: Spinal Muscular Atrophy
Intervention: Drug: ISIS-SMNRx
27 Active, not recruiting Clinical Study of Spinal Muscular Atrophy
Condition: Spinal Muscular Atrophy
Intervention:
28 Completed A Trial of Hydroxyurea in Spinal Muscular Atrophy
Condition: Spinal Muscular Atrophy
Intervention: Drug: Hydroxyurea
29 Completed Aerobic Training in Patients With Spinal Muscular Atrophy Type III
Condition: Spinal Muscular Atrophy
Intervention: Behavioral: Aerobic conditioning
30 Recruiting Valproate and Levocarnitine in Children With Spinal Muscular Atrophy
Condition: Spinal Muscular Atrophy
Interventions: Drug: Valproate, Levocarnitine;   Drug: Placebo
31 Recruiting Gene Transfer Clinical Trial for Spinal Muscular Atrophy Type 1
Condition: Spinal Muscular Atrophy 1
Intervention: Biological: scAAV9.CB.SMN
32 Completed Evaluation of the Muscle Strength and Motor Ability in Children With Spinal Muscle Atrophy(SMA) Treated With Valproic Acid
Condition: Spinal Muscular Atrophy
Intervention:
33 Not yet recruiting A Study of Multiple Doses of ISIS SMNRx (ISIS 396443) Delivered to Infants With Genetically Diagnosed and Presymptomatic Spinal Muscular Atrophy
Condition: Spinal Muscular Atrophy
Intervention: Drug: ISIS SMNRx (ISIS 396443)
34 Completed Safety and Efficacy of Olesoxime (TRO19622) in 3-25 Years SMA Patients.
Conditions: Spinal Muscular Atrophy Type II;   Spinal Muscular Atrophy Type III Non Ambulant
Interventions: Drug: Olesoxime;   Drug: Placebo
35 Unknown  Motor Development and Orthoses in Spinal Muscular Atrophy (SMA)
Condition: Spinal Muscular Atrophy
Intervention:
36 Not yet recruiting Study of Feasibility to Reliably Measure Functional Abilities' Changes in Nonambulant Neuromuscular Patients Without Trial Site Visiting
Conditions: Spinal Muscular Atrophy;   Neuromuscular Disorders
Intervention: Other: Direct current stimulation of cervical spinal cord
37 Unknown  A Pilot Therapeutic Trial Using Hydroxyurea in Type II and Type III Spinal Muscular Atrophy Patients
Condition: Muscular Atrophy, Spinal
Intervention: Drug: Hydroxyurea
38 Completed Phase II Study of Leuprolide and Testosterone for Men With Kennedy's Disease or Other Motor Neuron Disease
Conditions: Spinal Muscular Atrophy;   Amyotrophic Lateral Sclerosis;   Spinobulbar Muscular Atrophy
Interventions: Drug: leuprolide;   Drug: testosterone
39 Recruiting National Registry for Egyptian Pediatric Neuromuscular Diseases
Conditions: Spinal Muscular Atrophy;   Muscular Dystrophy;   Muscle Diseases;   Myasthenic Syndromes;   Polyneuropathies
Intervention:
40 Active, not recruiting Short and Long Term Treatment With 4-AP in Ambulatory SMA Patients
Condition: Spinal Muscular Atrophy
Interventions: Drug: 4-aminopyridine;   Drug: Placebo

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Indicates status has not been verified in more than two years