| 1 |
NCT02161848 |
Completed |
MRI Study - Chronic Progressive External Ophthalmoplegia |
- Chronic Progressive External Ophthalmoplegia
|
- Other: Magnetic Resonance Imaging
|
Observational |
|
|
Other |
- Time Perspective: Cross-Sectional
|
- Fat fraction in the muscles of the lower bag, thighs and calves
- Isokinetic muscle dynamometry of ankle flexion
- Isokinetic muscle dynamometry of ankle extension
- (and 2 more...)
|
133 |
All |
18 Years to 80 Years (Adult, Senior) |
NCT02161848 |
H-3-2012-163 (CPEO) |
CPEO |
June 2014 |
October 2015 |
October 2015 |
June 12, 2014 |
April 14, 2016 |
|
- Neuromuscular Research Unit
Copenhagen, Denmark
|
| 2 |
NCT02781493 |
Not yet recruiting |
Efficacy of Prucalopride Plus Polyethylene Glycol in Bowel Preparation for Colonoscopy |
- Prucalopride Plus Polyethylene Glycol in Bowel Preparation for Colonoscopyp
|
- Drug: 2 mg Prucalopride plus 2 L Polyethylene Glycol regimen
- Drug: 2 mg Placebo plus 2 L Polyethylene Glycol regimen
|
Interventional |
Phase 4 |
- Shandong University
- Binzhou People's Hospital
- Tai'an People's Hospital
- Linyi People's Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Difference of scores rating by Boston Bowel Preparation Scale between 2 groups.
- Polyp detection rate between 2 groups.
- rate of adverse events between 2 groups.
|
600 |
All |
18 Years to 70 Years (Adult, Senior) |
NCT02781493 |
2016SDU-QILU-06 |
|
June 2016 |
March 2017 |
March 2017 |
May 24, 2016 |
May 27, 2016 |
|
- Department of Gastroenterology, Qilu Hospital, Shandong University
Jinan, Shandong, China
|
| 3 |
NCT02073552 |
Completed |
Colon Cleansing Quality of Polyethylene Glycol Compared With Polyethylene Glycol Plus Ascorbic Acid. |
|
- Drug: Polyethylene glycol 4000
- Drug: Macrogol 3350 plus ascorbic acid
|
Interventional |
Phase 4 |
- Fundación Canaria Rafael Clavijo para la Investigación Biomédica
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Investigator)
- Primary Purpose: Diagnostic
|
- Colon cleansing
- Tolerance of bowel preparation
- Detection of colorectal neoplasia
|
472 |
All |
Child, Adult, Senior |
NCT02073552 |
REPREP1
2013-002506-31 |
REPREP1 |
May 2014 |
December 2015 |
May 2016 |
February 27, 2014 |
June 27, 2016 |
|
- Hospital Universitario de Canarias
Santa Cruz de Tenerife, Spain
|
| 4 |
NCT02551198 |
Unknown † |
Comparison of Polyethylene Glycol With Ascorbic Acid and Oral Sulfate Solution for Bowel Preparation |
|
- Drug: HAPREP®
- Drug: SUCLEAR®
|
Interventional |
Phase 3 |
- National Cancer Center, Korea
- Daehang Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Investigator)
- Primary Purpose: Treatment
|
- Adequacy of bowel preparation
- 5-point scale symptom questionnaire for drug tolerability
- Number of Participants with Adverse Events
- (and 2 more...)
|
184 |
All |
20 Years to 75 Years (Adult, Senior) |
NCT02551198 |
NCC2015-0210 |
|
November 2015 |
March 2016 |
September 2016 |
September 16, 2015 |
November 30, 2015 |
|
- National Cancer Center
Goyang-si, Gyeonggi-do, Korea, Republic of
|
| 5 |
NCT01778192 |
Completed |
A Randomized Prospective Trial Comparing Polyethylene Glycol and Sodium Picosulphate With Magnesium Citrate |
- Colorectal Cancer
- Colon Adenoma
|
- Drug: Polyethylene glycol
- Drug: Sodium picosulphate with magnesium citrate
|
Interventional |
Phase 3 |
- Korea University Anam Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Investigator)
- Primary Purpose: Supportive Care
|
- the quality of the bowel preparation using the Ottawa bowel preparation scale (OBPS)
- Completeness of the bowel preparation
- the patient's tolerability
- the side effects of the sodium picosulphate and magnesium citrate
|
200 |
All |
18 Years to 75 Years (Adult, Senior) |
NCT01778192 |
Korea University |
|
July 2012 |
November 2012 |
December 2012 |
January 29, 2013 |
January 31, 2013 |
|
- Division of Gastroenterology, Department of Internal Medicine, Korea University College of Medicine
Seoul, Korea, Republic of
|
| 6 |
NCT01929590 |
Completed |
Low-volume Polyethylene Glycol Bowel Preparation for Colonoscopy |
- Bowel Preparation for Colonoscopy
|
- Drug: PEG-3350 group 2
- Drug: PEG-3350 group 1
- Drug: PEG-3350 group 3
|
Interventional |
Phase 3 |
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Diagnostic
|
- satisfactory bowel preparation
- tolerability with bowel preparation
|
180 |
All |
18 Years to 80 Years (Adult, Senior) |
NCT01929590 |
end-407-11-11-1 |
|
October 2011 |
June 2012 |
June 2012 |
August 28, 2013 |
August 28, 2013 |
|
- Instituto Nacional de ciencias Médicas y Nutrición Salvador Zubirán
Mexico City, Distrito Federal, Mexico
|
| 7 |
NCT03067675 |
Active, not recruiting |
Triton Reference Database |
|
- Device: Topcon DRI OCT Triton (plus)
|
Observational |
|
- Topcon Medical Systems, Inc.
|
Industry |
- Observational Model: Cohort
- Time Perspective: Cross-Sectional
|
|
500 |
All |
18 Years and older (Adult, Senior) |
NCT03067675 |
Triton RDB |
|
March 1, 2017 |
August 30, 2017 |
September 30, 2017 |
March 1, 2017 |
August 4, 2017 |
|
- Southern California College of Optometry
Anaheim, California, United States - Accessoreyes Optometry
Pasadena, California, United States - Illinois College of Optometry
Chicago, Illinois, United States - (and 3 more...)
|
| 8 |
NCT01093274 |
Unknown † |
Efficacy and Safety of Polyethylene Glycol Compared With Sodium Picosulphate for Bowel Preparation Before Colonoscopy |
|
- Drug: Sodium Picosulphate
- Drug: Polyethylene Glycol
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Care Provider)
- Primary Purpose: Diagnostic
|
- Percentage of patients requiring repeat colonoscopy because of poor preparation
- Patient's satisfaction as measured by questionnaire and willingness to repeat same preparation on future examination
|
200 |
All |
18 Years to 80 Years (Adult, Senior) |
NCT01093274 |
Gal001 |
|
|
|
|
March 25, 2010 |
March 25, 2010 |
|
- Rabin Medical Center - Beilinson Hospital
Petach Tikva, Israel
|
| 9 |
NCT03080714 |
Active, not recruiting |
Triton Agreement and Precision Study |
|
- Device: Topcon DRI OCT Triton (plus)
- Device: 3D OCT-1 Maestro
|
Interventional |
Not Applicable |
- Topcon Medical Systems, Inc.
|
Industry |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Diagnostic
|
|
150 |
All |
18 Years and older (Adult, Senior) |
NCT03080714 |
Triton AP |
|
March 13, 2017 |
August 30, 2017 |
September 30, 2017 |
March 15, 2017 |
August 4, 2017 |
|
- Fischer Laser Eye Center
Willmar, Minnesota, United States
|
| 10 |
NCT01320059 |
Completed |
Study of 18F-Fluoro-PEG6-IPQA |
|
- Drug: 18F-PEG6-IPQA
- Procedure: Positron emission tomography (PET)
|
Interventional |
Phase 1 |
- M.D. Anderson Cancer Center
- United States Department of Defense
|
Other / U.S. Fed |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Diagnostic
|
- Optimum dosimetry of 18F-PEG6-IPQA sodium injection based on critical organ safety
|
6 |
All |
18 Years and older (Adult, Senior) |
NCT01320059 |
2009-0832
W81XWH-05-2-0027
NCI-2014-01375 |
|
February 2012 |
April 2016 |
April 2016 |
March 22, 2011 |
June 27, 2016 |
|
- University of Texas MD Anderson Cancer Center
Houston, Texas, United States
|
| 11 |
NCT01189409 |
Suspended |
Polyethylene Glycol (PEG) Versus Sennosides Study in Opioid-Induced Constipation in Cancer Patients |
|
- Drug: PEG then Senna
- Drug: Senna then PEG
|
Interventional |
Phase 4 |
- British Columbia Cancer Agency
|
Other |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Supportive Care
|
- Bowel Performance Scale (BPS)
- Patient preference
- Time (in days) to attain an ideal BPS score of Goal (patient's goal)
- rectal measures and incidence of cramps
|
64 |
All |
18 Years and older (Adult, Senior) |
NCT01189409 |
H0901329 |
|
June 2010 |
July 2018 |
July 2019 |
August 26, 2010 |
December 26, 2017 |
|
- BC Cancer Agency
Vancouver, British Columbia, Canada
|
| 12 |
NCT03107104 |
Active, not recruiting |
Triton Fundus Autofluorescence and Fluorescein Angiography |
- Medical Need for Fluorescein Angiography Imaging
|
- Device: Topcon DRI OCT Triton (plus)
- Device: TRC-50DX retinal camera
|
Interventional |
Not Applicable |
- Topcon Medical Systems, Inc.
|
Industry |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Diagnostic
|
- Fundus autofluorescence image quality
- Fluorescein angiography image quality at 120 seconds to 300 seconds after dye injection
- Fluorescein angiography image quality at greater than 300 seconds after dye injection
|
100 |
All |
18 Years and older (Adult, Senior) |
NCT03107104 |
Triton FA FAF |
|
March 30, 2017 |
August 30, 2017 |
September 30, 2017 |
April 11, 2017 |
August 4, 2017 |
|
- Vitreous Retina Macula Consultants of New York
New York, New York, United States
|
| 13 |
NCT03011788 |
Recruiting |
Polyethylene Glycol Cleansing in Patients at High Risk for Poor Bowel Preparation |
|
- Drug: Golytely Oral Solution
|
Interventional |
Not Applicable |
- VA Connecticut Healthcare System
|
U.S. Fed |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Investigator)
- Primary Purpose: Screening
|
- Boston Bowel Preparation Scale (BBPS)
- Adenoma detection rate
- patient tolerability of preparation using the validated Mayo clinic bowel prep tolerability questionnaire
|
270 |
All |
18 Years and older (Adult, Senior) |
NCT03011788 |
AN0011 |
|
January 2017 |
January 2018 |
June 2018 |
January 5, 2017 |
January 6, 2017 |
|
- West Have VAMC
West Haven, Connecticut, United States
|
| 14 |
NCT02956057 |
Completed |
Polyethylene Glycol Versus Low Volume Solutions Prior to Colonoscopy |
|
- Drug: Polyethylene Glycols
- Drug: Natrium picosulfate / Magnesium citrate
- Drug: Polyethylene glycol / Ascorbic acid
|
Interventional |
Phase 4 |
- Tomas Bata Hospital, Czech Republic
- Brno University Hospital
- Faculty Hospital Kralovske Vinohrady
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Quality of bowel preparation using the Aronchick scale ( score 1+2)
- Tolerance of bowel preparation assessed by 5 point VAS ( score 1+2)
|
1044 |
All |
18 Years and older (Adult, Senior) |
NCT02956057 |
BN102016 |
|
November 2016 |
May 2017 |
August 2017 |
November 4, 2016 |
October 13, 2017 |
|
- Faculty Hospital Kralovske Vinohrady
Prague, Czechia
|
| 15 |
NCT03022383 |
Enrolling by invitation |
TopQ Cutoff Threshold Validation Study for DRI OCT Triton Plus |
|
- Device: DRI OCT Triton plus
|
Interventional |
Not Applicable |
- Topcon Medical Systems, Inc.
|
Industry |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Diagnostic
|
- Measurement Variability of Signal to Noise Ratio
|
15 |
All |
18 Years and older (Adult, Senior) |
NCT03022383 |
Topcon Triton 1222-2016 |
|
January 2017 |
February 2017 |
|
January 16, 2017 |
January 16, 2017 |
|
- Topcon Medical Systems Inc.
Oakland, New Jersey, United States
|
| 16 |
NCT00153114 |
Completed |
PolyethyleneGlycol3350 Laxative vs Placebo in Constipated Children |
|
- Drug: polyethyleneglycol3350
|
Interventional |
Phase 4 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double
- Primary Purpose: Treatment
|
- Greater than 2 bowel movements per week
- Analysis of individual ROME I criteria
- Safety (adverse event and laboratory testing)
|
100 |
All |
4 Years to 16 Years (Child) |
NCT00153114 |
851-15 |
|
January 2003 |
September 2004 |
|
September 12, 2005 |
February 7, 2013 |
|
- Boston, Massachusetts, United States
- Morristown, New Jersey, United States
- Pittsburgh, Pennsylvania, United States
|
| 17 |
NCT00828984 |
Completed
Has Results |
Macrogol 3350-based Oral Osmotic Laxative in Preventing Cancer in Patients at Risk of Colorectal Cancer |
- Adenomatous Polyp
- Colorectal Carcinoma
|
- Drug: macrogol 3350-based oral osmotic laxative
- Other: Placebo
- Other: Laboratory Biomarker Analysis
|
Interventional |
Phase 2 |
- National Cancer Institute (NCI)
|
NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Prevention
|
- Difference (After Treatment Minus Before Treatment) of EGFR Expression
- Change in ACF Count as Measured in Endoscopically Normal (Non-ACF) Mucosal Biopsies
- Change in Ki-67 (Proliferation) Expression as Measured in Endoscopically Normal (Non-ACF) Mucosal Biopsies
- (and 3 more...)
|
87 |
All |
18 Years and older (Adult, Senior) |
NCT00828984 |
NCI-2009-01113
NCI 06-8-01
CDR0000632553
N01CN35157
NCI06-8-01
NWU06-8-01
P30CA060553 |
|
October 2009 |
October 2014 |
October 2014 |
January 26, 2009 |
April 18, 2017 |
January 19, 2017 |
- University of Chicago
Chicago, Illinois, United States - NorthShore University HealthSystem-Evanston Hospital
Evanston, Illinois, United States - Boston Medical Center
Boston, Massachusetts, United States
|
| 18 |
NCT02526823 |
Recruiting |
Clinical Application of Polyethylene Glycol Liposome Doxorubicin (PLD) in Primary Lymphoma |
- Lymphoma, Non-Hodgkin;Hodgkin Disease
|
- Drug: R-CHOP/CHOPE or ABVD chemotherapy regimen
- Drug: R-CDOP/CDOPE or DBVD chemotherapy regimen
|
Interventional |
Phase 4 |
- Shandong Provincial Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Treatment
|
- Percentage of patients with complete remission （CR）
|
360 |
All |
18 Years to 80 Years (Adult, Senior) |
NCT02526823 |
ShandongPH01 |
|
August 2015 |
August 2017 |
February 2019 |
August 18, 2015 |
April 19, 2016 |
|
- Department of Hematology, Provincial Hospital Affiliated to Shandong University
Jinan, Shandong, China
|
| 19 |
NCT02981758 |
Recruiting |
Accurate Display of Postpartum Hemorrhage Using Triton (ADOPT) |
- Post-partum Hemorrhage (PPH)
|
|
Observational |
|
- Hackensack University Medical Center
|
Other |
- Observational Model: Cohort
- Time Perspective: Retrospective
|
- Quantification of blood loss during vaginal deliveries
- Comparison of quantified blood loss (hemoglobin loss) using the The Triton™ System of mobile imaging with computer vision and learning algorithms compared to estimations of blood loss given by the provider.
- Comparison of quantified blood loss (hemoglobin loss) using the The Triton™
|
300 |
Female |
Child, Adult, Senior |
NCT02981758 |
Pro2016-0184 |
ADOPT |
July 2016 |
July 2017 |
July 2017 |
December 5, 2016 |
December 5, 2016 |
|
- Hackensack University Medical Center
Hackensack, New Jersey, United States
|
| 20 |
NCT03100513 |
Recruiting |
PEG (Polyethylene Glycol)Versus Lactulose For Treatment Of Overt Hepatic Encephalopathy |
|
- Drug: Lactulose
- Drug: Polyethylene Glycol
|
Interventional |
Phase 4 |
- Sherief Abd-Elsalam
- Tanta University
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- 1 or more in HE grade improvement at 24 hours
- Time to HE resolution
- Overall length of stay
|
100 |
All |
Child, Adult, Senior |
NCT03100513 |
Hanan Soliman |
|
March 11, 2017 |
October 2019 |
December 2019 |
April 4, 2017 |
April 27, 2017 |
|
- Tropical medicine dept.-Tanta university hospital
Cairo, Egypt
|
| 21 |
NCT03356015 |
Not yet recruiting |
Comparison Between 3-L and 4-L Polyethylene Glycol in Bowel Preparation |
- Bowel Preparation Scale
- Adenoma Detection Rate
|
- Drug: 4L Polyethylene Glycol
- Drug: 3L Polyethylene Glycol
|
Interventional |
Phase 4 |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Investigator, Outcomes Assessor)
- Primary Purpose: Screening
|
- the Boston Bowel Preparation Scale
- Polyp detection rate
- Adenoma detection rate
- The mean number of incremental adenomas
|
260 |
All |
18 Years to 75 Years (Adult, Senior) |
NCT03356015 |
PEG-171116 |
|
December 1, 2017 |
January 1, 2018 |
February 1, 2018 |
November 29, 2017 |
November 29, 2017 |
|
- Changhai Hospital, Second Military Medical University
Shanghai, China
|
| 22 |
NCT00153140 |
Completed |
Polyethyleneglycol3350 vs Tegaserod in Treatment of Patients With Chronic Constipation |
|
- Drug: polyethyleneglycol3350
|
Interventional |
Phase 4 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- A successful outcome is defined as no longer meeting the definition of constipation using ROME I criteria
- Analysis of individual ROME I criteria
- Safety (adverse event review)
|
239 |
All |
18 Years to 64 Years (Adult) |
NCT00153140 |
851-ZCC |
|
July 2004 |
October 2004 |
|
September 12, 2005 |
February 7, 2013 |
|
- Mobile, Alabama, United States
- Glendale, Arizona, United States
- Anaheim, California, United States
- (and 22 more...)
|
| 23 |
NCT02657564 |
Recruiting |
Renal Safety of Bowel Preparation With Polyethylene Glycol |
|
- Drug: Polyethylene glycol (PEG)
|
Interventional |
Not Applicable |
- Evergreen General Hospital, Taiwan
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Health Services Research
|
- Acute kidney injury (blood tests for srum BUN and creatinine).
- Electrolyte disturbance (serum caclium, phosphate, sodium, potassium, chloride, and magnesium).
|
1152 |
All |
40 Years and older (Adult, Senior) |
NCT02657564 |
ZEH-2016-1 |
|
January 2016 |
June 2017 |
June 2017 |
January 18, 2016 |
August 2, 2016 |
|
- Evergreen General Hospital
Taoyuan, Taiwan
|
| 24 |
NCT01923376 |
Withdrawn |
Hepatic Encephalopathy: Lactulose or Polyethylene Glycol (H.E.L.P.) |
- Hepatic Encephalopathy
- HE
- Cirrhosis
- (and 2 more...)
|
- Drug: Lactulose
- Drug: Polyethylene Glycol 3350
|
Interventional |
Not Applicable |
- New York Methodist Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Improvement of cognition
- Duration of hospital stay
|
0 |
All |
18 Years to 80 Years (Adult, Senior) |
NCT01923376 |
401550 |
HELP |
February 2013 |
February 2014 |
February 2014 |
August 15, 2013 |
May 12, 2015 |
|
- New York Methodist Hospital
Brooklyn, New York, United States
|
| 25 |
NCT02467790 |
Unknown † |
Polyethylene Glycol Loxenatide Pharmacokinetics Study in Subjects With Normal and Insufficiency Renal Function |
|
|
Interventional |
Phase 1 |
- Jiangsu Hansoh Pharmaceutical Co., Ltd.
|
Industry |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Pharmacokinetic index
- Incidence of adverse events and serious adverse events
|
24 |
All |
31 Years to 65 Years (Adult) |
NCT02467790 |
PEX168-Ih |
|
February 2015 |
March 2016 |
May 2016 |
June 10, 2015 |
January 26, 2016 |
|
- Third Xiangya Hospital, Central South Univety
Chang Sha, Hunan, China
|
| 26 |
NCT02419534 |
Unknown † |
Pediatrics Anal Fissures Treatment With Polyethylene Glycol |
|
- Drug: Polyethylene glycol
- Drug: Polyethylene glycol with Diltiazem
|
Interventional |
Phase 4 |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Number of cases with healed anal fissure as detected by clinical physical exam
- Number cases with painless bowel movement detected during clinical visits or phone interviews
- Number of individuals with minimal or no straining during bowel movement detected during clinical visits or phone interviews
- (and 3 more...)
|
46 |
All |
up to 13 Years (Child) |
NCT02419534 |
14/4293 |
|
November 2014 |
November 2016 |
November 2016 |
April 17, 2015 |
March 1, 2016 |
|
- College of medicine, king saud university
Riyadh, Nejd Province - Central, Saudi Arabia
|
| 27 |
NCT01626040 |
Completed |
Evaluation of One-day Polyethylene Glycol Powder Solution for Colonoscopy in Children |
- Water-Electrolyte Imbalance
|
- Drug: polyethylene glycol powder
|
Observational |
|
- Children's Hospital of Philadelphia
|
Other |
- Observational Model: Case-Only
- Time Perspective: Prospective
|
- electrolyte disturbances
- PEG-P preparation tolerance
- Colonoscopy preparation efficacy
- Effective communication
|
178 |
All |
1 Year to 18 Years (Child, Adult) |
NCT01626040 |
12-008643 |
|
June 2012 |
January 2014 |
January 2014 |
June 22, 2012 |
January 17, 2014 |
|
- Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, United States
|
| 28 |
NCT01901510 |
Completed |
Panchromoendoscopy Using Oral Indigo Carmine Mixed With Polyethylene Glycol Prep |
|
- Drug: Chromoendoscopy (Indigo Carmine)
- Other: Control
|
Interventional |
Phase 1 |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Outcomes Assessor)
- Primary Purpose: Diagnostic
|
- Dose of indigo carmine needed to provide adequate chromoendoscopy of the right sided colon
- Cecal intubation rate
- Time to cecal intubation
- (and 7 more...)
|
21 |
All |
50 Years to 75 Years (Adult, Senior) |
NCT01901510 |
12-009897 |
|
May 2013 |
July 2014 |
July 2014 |
July 17, 2013 |
March 3, 2015 |
|
- Mayo Clinic in Arizona
Scottsdale, Arizona, United States
|
| 29 |
NCT03410524 |
Recruiting |
Evaluation of Oral Simethicone With Low Volume Polyethylene Glycol Bowel Preparation During Colonoscopy |
|
- Drug: Simethicone Solution
- Drug: Water
|
Interventional |
Phase 3 |
- University of Nevada, Reno
- Gastroenterology Consultants
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Care Provider, Investigator)
- Primary Purpose: Diagnostic
|
- Intraluminal Bubbles Scale
- Boston Bowel Preparation Scale
- Cecal insertion time
- (and 6 more...)
|
250 |
All |
18 Years to 80 Years (Adult, Senior) |
NCT03410524 |
1139179 |
|
January 9, 2018 |
October 31, 2018 |
December 31, 2018 |
January 25, 2018 |
January 25, 2018 |
|
- Gastroenterology Consultants Reno - North Office and Endoscopy Center
Reno, Nevada, United States - Gastroenterology Consultants Reno - South Meadows Office and Endoscopy Center
Reno, Nevada, United States
|
| 30 |
NCT00558376 |
Terminated |
Polyethylene Glycol Versus Sodium Phosphate for Colon Preparation After Failure of First Preparation for Colonoscopy |
|
- Drug: polyethylene glycol
- Drug: Sodium phosphate
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Investigator)
- Primary Purpose: Treatment
|
- Colon cleanliness at the second colonoscopy
- Tolerability of purgative regimen
|
23 |
All |
18 Years to 70 Years (Adult, Senior) |
NCT00558376 |
SHEBA-07-4884-SBH-CTIL |
|
January 2008 |
March 2009 |
March 2009 |
November 14, 2007 |
May 5, 2009 |
|
- Sheba_Medical_Center
Tel-Hashomer, Israel
|
| 31 |
NCT03148002 |
Recruiting |
Peritoneal Dialysis Pilot Study: Evaluating Polyethylene Glycol (PEG) for Constipation |
- Constipation
- Peritoneal Dialysis Complication
|
- Drug: Current Bowel Protocol (senna/lactulose)
- Drug: PEG Bowel Protocol (PEG/lactulose)
|
Interventional |
Phase 4 |
- Jaclyn Tran
- Nova Scotia Health Authority
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Rate of constipation treatment success
- Number of patients with laxative related adverse effects.
- Mean change from baseline on the PAC-SYM questionnaire
- (and 2 more...)
|
30 |
All |
Child, Adult, Senior |
NCT03148002 |
PDBowel2017 |
|
July 7, 2017 |
November 1, 2017 |
February 1, 2018 |
May 10, 2017 |
July 19, 2017 |
|
- Queen Elizabeth Health Sciences Centre
Halifax, Nova Scotia, Canada
|
| 32 |
NCT03329339 |
Completed |
The Effect of 1L Polyethylene Glycol Plus Ascorbic Acid With Prepackaged Low-Residue Diet for Bowel Preparation |
- Colonoscopy
- Colon Polyp
- Bowel Preparation Solutions
|
- Procedure: 1 L PEG with ascorbic acid with prepackaged, low residue diet
|
Interventional |
Not Applicable |
- Seoul National University Bundang Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Achievement of preparation adequacy
- Tolerability and adverse events
|
200 |
All |
18 Years to 85 Years (Adult, Senior) |
NCT03329339 |
B-1505-297-003 |
|
May 15, 2015 |
December 31, 2016 |
December 31, 2016 |
November 6, 2017 |
November 6, 2017 |
|
|
| 33 |
NCT02396017 |
Unknown † |
Split-dose Versus Single-dose Polyethylene Glycol Regimen for Capsule Endoscopy |
|
- Device: Capsule endoscopy
- Drug: Polyethylene Glycol
|
Interventional |
Phase 4 |
- Centro Hospitalar Lisboa Ocidental
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Investigator)
- Primary Purpose: Diagnostic
|
- Small-bowel cleanliness
- The number of all the observed lesions
- The clinical tolerance questionnaire
- The transit time
|
50 |
All |
18 Years and older (Adult, Senior) |
NCT02396017 |
SPLIT-PEG-CE |
|
March 2015 |
May 2015 |
May 2015 |
March 24, 2015 |
March 24, 2015 |
|
- Gastroenterology Department, Hospital Egas Moniz
Lisboa, Portugal
|
| 34 |
NCT02178033 |
Unknown † |
The Impact of Split Dose of Low-volume Polyethylene Glycol on Adenoma Detection Rate |
|
- Drug: Split dose low-volume PEG solution
|
Interventional |
Not Applicable |
- Valduce Hospital
- Istituto Clinico Humanitas
- Istituti Ospitalieri di Cremona
- Nuovo Regina Margherita Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Investigator)
- Primary Purpose: Diagnostic
|
- Adenoma Detection Rate
- Advanced Adenoma Detection Rate
- Flat/depressed Adenoma Detection Rate
- (and 5 more...)
|
514 |
All |
50 Years to 69 Years (Adult, Senior) |
NCT02178033 |
Split dose-ADR |
|
January 2014 |
December 2014 |
January 2015 |
June 30, 2014 |
June 30, 2014 |
|
- Ospedale VAlduce, Gastroenterology Unit
Como, Italy - IRCCS Istituto Clinico Humanitas; Gastroenterology Unit
Milano, Italy
|
| 35 |
NCT00565669 |
Completed |
Evaluation of Blink Tears and Systane Concomitant With Restasis for the Treatment of Dry Eye Symptoms |
|
- Drug: Cyclosporin A Restasis®
|
Interventional |
Not Applicable |
- Medical University of South Carolina
|
Other |
- Allocation: Randomized
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
|
|
20 |
All |
18 Years and older (Adult, Senior) |
NCT00565669 |
SEI-07-003 |
|
October 2007 |
October 2008 |
October 2008 |
November 30, 2007 |
May 4, 2016 |
|
- Medical University of South Carolina, Storm Eye Institute
Charleston, South Carolina, United States
|
| 36 |
NCT03448770 |
Recruiting |
To Compare Efficacy and Safety of Lactulose Versus Polyethylene Glycol for Treatment of Overt Hepatic Encephalopathy in Cirrhotics. |
|
- Drug: PEG- 17 gm sachet
- Drug: Lactulose : 20-30gm
|
Interventional |
Not Applicable |
- Institute of Liver and Biliary Sciences, India
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Complete reversal of hepatic encephalopathy in both groups.
- Improvement in hepatic encephalopathy by two grades in both groups
- Length of Intensive Care Unit stay in both groups
- (and 2 more...)
|
110 |
All |
18 Years to 65 Years (Adult) |
NCT03448770 |
ILBS-cirrhosis-14 |
|
August 1, 2017 |
July 31, 2018 |
July 31, 2018 |
February 28, 2018 |
February 28, 2018 |
|
- Institute of liver and Biliary Sciences
New Delhi, Delhi, India
|
| 37 |
NCT00153153 |
Completed |
Extended Use of Polyethyleneglycol3350 Laxative in Constipated Patients |
|
- Drug: polyethyleneglycol3350
|
Interventional |
Phase 4 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double
- Primary Purpose: Treatment
|
- A successful outcome is defined as no longer meeting the definition of constipation using ROME I criteria
- Analysis of individual ROME I criteria
- Safety (adverse events and laboratory testing)
|
300 |
All |
18 Years and older (Adult, Senior) |
NCT00153153 |
851-CR1 |
|
August 2003 |
December 2004 |
|
September 12, 2005 |
February 7, 2013 |
|
- Hoover, Alabama, United States
- Mobile, Alabama, United States
- Pell City, Alabama, United States
- (and 42 more...)
|
| 38 |
NCT02292459 |
Withdrawn |
Efficacy and Safety of Polyethylene Glycol 3350 (PEG 3350) for Relief of Constipation (MK-8114-005) |
|
- Drug: Polyethylene Glycol 3350 Powder for Solution (PEG 3350)
- Drug: Polyethylene Glycol 4000 Powder for Solution (PEG 4000)
|
Interventional |
Phase 3 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Number of bowel movements per week
- Time to first bowel movement
- Number of participants who experience changes in straining and hard or lumpy stools
- (and 2 more...)
|
0 |
All |
18 Years and older (Adult, Senior) |
NCT02292459 |
18128
CL2012-15
8114-005 |
|
December 2015 |
December 2015 |
December 2015 |
November 17, 2014 |
July 16, 2015 |
|
|
| 39 |
NCT03060512 |
Completed |
To Evaluate Patient Preference of Movantik and Polyethylene Glycol 3350 for Opioid Induced Constipation |
- Opioid Induced Constipation
|
- Drug: Polyethylene Glycol 3350
- Drug: Movantik
|
Interventional |
Phase 4 |
- AstraZeneca
- QuintilesIMS, Inc.
|
Industry / Other |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Patient reported preference for Movantik or Polyethylene Glycol 3350 measured using a 7-point preference scale
- Patient reported influence of each medication characteristic that contributed to their overall Preference.
|
273 |
All |
18 Years to 84 Years (Adult, Senior) |
NCT03060512 |
D3820L00017 |
|
March 2, 2017 |
August 23, 2017 |
August 23, 2017 |
February 23, 2017 |
September 8, 2017 |
|
- Research Site
Huntsville, Alabama, United States - Research Site
Phoenix, Arizona, United States - Research Site
Phoenix, Arizona, United States - (and 50 more...)
|
| 40 |
NCT01929668 |
Completed |
Comparison of 4L Polyethylene Glycol and 2L Polyethylene Glycol With Ascorbic Acid in Inactive UC Patients |
|
- Drug: polyethylene glycol
- Drug: Ascorbic Acid
|
Interventional |
Not Applicable |
- Kyungpook National University
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Screening
|
- Number of patients who are willing to use the same preparation method for the next colonoscopy.
- Number of patients who have ulcerative colitis symptom aggravation within 30 days after bowel preparation, measured by simple clinical colitis activity index (SCCAI).
|
114 |
All |
18 Years to 80 Years (Adult, Senior) |
NCT01929668 |
2013-07-036-002 |
2SCANI |
August 2013 |
December 2014 |
December 2014 |
August 28, 2013 |
April 28, 2016 |
|
- Keimyung University Dongsan Medical Center
Daegu, Korea, Republic of
|
| 41 |
NCT01610895 |
Unknown † |
Split Dose Polyethylene Glycol (PEG) + Clear Fluids Versus Split Dose PEG + Low-Residue Diet |
|
- Other: Split-dose PEG Based Lavage (2L + 2L) with Low-Fibre Lunch Dietary instructions
- Other: Split-dose PEG Based Lavage (2L + 2L) with Standard Dietary Instructions
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
|
- Quality of Bowel Cleanliness
- Patient satisfaction with preparation
|
345 |
All |
18 Years to 74 Years (Adult, Senior) |
NCT01610895 |
24206 |
BP |
December 2011 |
August 2012 |
October 2012 |
June 4, 2012 |
June 4, 2012 |
|
- Forzani & MacPhail Colon Cancer Screening Centre, Alberta Health Services
Calgary, Alberta, Canada
|
| 42 |
NCT01965496 |
Completed |
A Phase I Study of Polyethylene Glycol Loxenatide in Patients With Type 2 Diabetes |
|
|
Interventional |
Phase 1 |
- Jiangsu HengRui Medicine Co., Ltd.
- People's Liberation Army General Hospital of Chengdu Military Region
|
Industry / Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- To assess HbA1C levels after 14 weeks continuous treatment
- To assess Fasting blood glucose levels
|
64 |
All |
20 Years to 70 Years (Adult, Senior) |
NCT01965496 |
PEX168-I-05 |
|
March 2012 |
March 2013 |
April 2013 |
October 18, 2013 |
October 18, 2013 |
|
- People's Liberation Army General Hospital of Chengdu Military Region
Chengdu, China
|
| 43 |
NCT01965509 |
Completed |
A PK/PD Study of Polyethylene Glycol Loxenatide in Patients With Type 2 Diabetes |
|
|
Interventional |
Phase 2 |
- Jiangsu HengRui Medicine Co., Ltd.
- China-Japan Friendship Hospital
|
Industry / Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- To assess HbA1C levels after treatment
- To assess Fasting blood glucose levels
|
120 |
All |
20 Years to 70 Years (Adult, Senior) |
NCT01965509 |
PEX168-I-06 |
|
May 2012 |
August 2013 |
October 2013 |
October 18, 2013 |
October 18, 2013 |
|
- China-Japan Friendship Hospital
Beijing, China
|
| 44 |
NCT01589640 |
Unknown † |
Patient Satisfaction and Tear Osmolarity With the Use of Blink Tears, Blink Gel Tears and Systane Balance |
|
- Other: Blink Tears lubricating Eye Drops
- Other: Blink Gel Tears Lubricating Eye Drops
- Other: Systane Balance Lubricant Eye Drop
|
Observational |
|
- Ophthalmic Consultants of Connecticut
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Primary efficacy variable is tear osmolarity
- Secondary efficacy variable is the Patient Symptom Questionnaire
|
60 |
All |
18 Years and older (Adult, Senior) |
NCT01589640 |
EDD-BLNK-12-001 |
|
May 2012 |
September 2012 |
October 2012 |
May 2, 2012 |
May 2, 2012 |
|
- Ophthalmic Consultants of Connecticut
Fairfield, Connecticut, United States
|
| 45 |
NCT01164410 |
Completed |
The Efficacy Side Effects and the Tolerance of Polyethylene Glycol 3350 as a Bowel Prep in Children |
|
|
Observational |
|
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- MiralaxTM combined with Gatorade GTM given the day prior to colonoscopy is a safe, tolerable and efficacious cleansing regimen for colonoscopy in children.
|
45 |
All |
5 Years to 21 Years (Child, Adult) |
NCT01164410 |
CCF 09-378 |
|
August 2009 |
April 2010 |
June 2010 |
July 16, 2010 |
October 24, 2017 |
|
- Cleveland Clinic Childrens Hospital
Cleveland, Ohio, United States
|
| 46 |
NCT01610856 |
Completed |
Single Dose Versus Split Dose Polyethylene Glycol-based Colonic Lavage for Colonoscopy |
|
- Drug: Polyethylene Glycol
- Drug: polyethylene glycol
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Care Provider, Investigator, Outcomes Assessor)
|
- The Ottawa Bowel Preparation Score
|
250 |
All |
50 Years to 75 Years (Adult, Senior) |
NCT01610856 |
21972
Ethics ID 21972 |
|
March 2010 |
June 2010 |
June 2010 |
June 4, 2012 |
June 4, 2012 |
|
- Forzani & MacPhail Colon Cancer Screening Centre
Calgary, Alberta, Canada
|
| 47 |
NCT02451527 |
Completed |
The Pharmacokinetic Study of the Combination of Digoxin and Polythylene Glycol Loxenatide Injection in Healthy Subjects |
|
- Drug: Digoxin
- Drug: PEX168
|
Interventional |
Phase 1 |
- First Affiliated Hospital Xi'an Jiaotong University
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Composite of pharmacokinetic (PK) parameters of digoxin with and without PEX168 in plasma and urine (cmax, t 1/2)
- Number of Participants with Adverse Events as a Measure of Safety and Tolerability
|
16 |
Male |
18 Years to 45 Years (Adult) |
NCT02451527 |
2013L02060 |
|
May 2015 |
September 2015 |
July 2016 |
May 22, 2015 |
November 30, 2016 |
|
- The First Affiliated Hospital of Xi'an Jiaotong University
Xian, Shaanxi, China
|
| 48 |
NCT01707667 |
Completed
Has Results |
Study to Investigate Prucalopride vs. Polyethylene Glycol 3350 on Colon Activity |
|
- Drug: prucalopride
- Drug: PEG 3350
|
Interventional |
Phase 4 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- The Number of High-Amplitude Propagating Contractions (HAPC)
- Area Under the Concentration Curve (AUC) of All HAPCs
- The Mean Amplitude of HAPC
- (and 4 more...)
|
13 |
All |
18 Years to 75 Years (Adult, Senior) |
NCT01707667 |
SPD555-403
2012-002495-13 |
|
January 2013 |
November 2013 |
December 2013 |
October 16, 2012 |
October 22, 2014 |
October 22, 2014 |
- Oklahoma Foundation for Digestive Research
Oklahoma City, Oklahoma, United States - UNIVERSITY OF LEUVEN, UNVERSITY HOSPITAL, Gasthuisberg
Leuven, Belgium - Barts Health NHS Trust
Whitechapel, London, United Kingdom
|
| 49 |
NCT00153127 |
Completed |
Comparison of PolyethyleneGlycol and Placebo for Relief of Constipation From Constipating Medications |
|
- Drug: polyethyleneglycol3350
|
Interventional |
Phase 4 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double
|
- A successful outcome is defined as no longer meeting the definition of constipation using ROME I criteria
- Analysis of individual ROME I criteria
- Safety (adverse event and laboratory testing)
|
100 |
All |
19 Years and older (Adult, Senior) |
NCT00153127 |
851-17 |
|
November 2001 |
September 2004 |
|
September 12, 2005 |
February 7, 2013 |
|
- Mobile, Alabama, United States
- St. Petersburg, Florida, United States
- St. Louis, Missouri, United States
- Raleigh, North Carolina, United States
|
| 50 |
NCT01976858 |
Completed |
A Phase I Study of 8-week Continuous Treatment With Polyethylene Glycol Loxenatide in Patients With Type 2 Diabetes |
|
|
Interventional |
Phase 1 |
- Jiangsu HengRui Medicine Co., Ltd.
- Beijing Tongren Hospital
|
Industry / Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- To determine serum concentrations of PEX168
- To determin HbA1c levels of PEX168
|
50 |
All |
20 Years to 65 Years (Adult) |
NCT01976858 |
PEX168-I-03 |
|
June 2011 |
September 2011 |
December 2011 |
November 6, 2013 |
November 6, 2013 |
|
- Beijing tongren hospital
Beijing, Beijing, China
|
Create an RSS feed from your search for:
Download the search results for: