29 studies found for:    "potassium-aggravated myotonia" OR "Myotonic Disorders" OR "Myotonia Fluctuans"
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Rank Status Study
1 Enrolling by invitation Lamotrigine as Treatment of Myotonia
Conditions: Dystrophia Myotonica Type 1;   Myotonia Congenita;   Paramyotonia Congenita;   Hyperkalemic Periodic Paralysis;   Potassium-Aggravated Myotonia
Interventions: Drug: Lamotrigine;   Drug: Placebo
2 Recruiting Myotonic Dystrophy Family Registry
Conditions: Myotonic Dystrophy;   Congenital Myotonic Dystrophy;   Myotonic Dystrophy 1;   Myotonic Dystrophy 2;   Dystrophia Myotonica;   Dystrophia Myotonica 1;   Dystrophia Myotonica 2;   Myotonia Dystrophica;   Myotonic Dystrophy, Congenital;   Myotonic Myopathy, Proximal;   PROMM (Proximal Myotonic Myopathy);   Proximal Myotonic Myopathy;   Steinert Disease;   Steinert Myotonic Dystrophy;   Steinert's Disease;   Myotonia Atrophica
Intervention: Other: Patient-entered data
3 Completed Characteristics of Nondystrophic Myotonias
Conditions: Nondystrophic Myotonias;   Myotonia Congenita;   Myotonic Disorders
Intervention:
4 Completed Mexiletine and Non Dystrophic Myotonias
Conditions: Non-dystrophic Myotonias;   Paramyotonia Congenita;   Myotonia Congenita
Interventions: Drug: Mexiletine;   Drug: placebo
5 Completed Phase III Randomized, Double-Blind, Placebo-Controlled Study of Dichlorphenamide for Periodic Paralyses and Associated Sodium Channel Disorders
Conditions: Paralysis, Hyperkalemic Periodic;   Hypokalemic Periodic Paralysis;   Paramyotonia Congenita
Intervention: Drug: dichlorphenamide
6 Completed Relations Between Myotonia and Fitness
Condition: Congenital Myotonia
Intervention: Other: Training
7 Enrolling by invitation Derivation of Human Induced Pluripotent Stem (iPS) Cells to Heritable Cardiac Arrhythmias
Conditions: Inherited Cardiac Arrythmias;   Long QT Syndrome (LQTS);   Brugada Syndrome (BrS);   Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT);   Early Repolarization Syndrome (ERS);   Arrhythmogenic Cardiomyopathy (AC, ARVD/C);   Hypertrophic Cardiomyopathy (HCM);   Dilated Cardiomyopathy (DCM);   Muscular Dystrophies (Duchenne, Becker, Myotonic Dystrophy);   Normal Control Subjects
Intervention:
8 Completed DM1 Heart Registry - DM1 Respiratory Registry
Condition: Myotonic Dystrophy
Intervention:
9 Active, not recruiting Efficacy and Tolerance of Early Launching of Nocturnal Non Invasive
Conditions: Myopathy;   Muscular Weakness;   Respiratory Insufficiency
Intervention: Device: Bilevel pressure ventilator
10 Unknown  RAMYD Study - Evaluation of Arrhythmic Risk in Myotonic Dystrophy
Conditions: Myotonic Dystrophy;   Sudden Cardiac Death
Interventions: Procedure: Electrophysiological study;   Device: pacemaker (PM) implant, internal cardiac defibrillator (ICD) implant, loop-recorder implant
11 Unknown  Safety and Efficacy Study of Recombinant Human Insulin-Like Growth Factor-I/Recombinant Human Insulin-Like Growth Factor Binding Protein-3 (rhIGF-I/rhIGFBP-3) In Myotonic Dystrophy Type 1
Condition: Myotonic Dystrophy Type 1
Interventions: Drug: rhIGF-I/rhIGFBP-3;   Drug: placebo
12 Completed
Has Results
Effects of SomatoKine (Iplex)Recombinant Human Insulin-like Growth Factor-1/Recombinant Human Insulin-like Growth Factor-binding Protein-3 (rhIGF-I/rhIGFBP-3) in Myotonic Dystrophy Type 1 (DM1)
Condition: Myotonic Dystrophy
Intervention: Drug: SomatoKine/IPLEX
13 Recruiting Observational Prolonged Trial in Myotonic Dystrophy Type 1
Condition: Myotonic Dystrophy Type 1
Intervention: Behavioral: Behavioural change intervention
14 Recruiting Clinical Efficacy Trial of Mexiletine for Myotonic Dystrophy Type 1
Condition: Myotonic Dystrophy
Interventions: Drug: Mexiletine;   Drug: Placebo
15 Recruiting Children's Health Research Institute(CHRI), Stanford Lucile Packard Children Hospital (LPCH) Protocol on Myotonic Dystrophy
Condition: Myotonic Dystrophy Type 1
Intervention:
16 Recruiting A Safety andTolerability Study of Multiple Doses of ISIS-DMPKRx in Adults With Myotonic Dystrophy Type 1
Condition: Myotonic Dystrophy Type 1
Interventions: Drug: ISIS-DMPKRx;   Drug: Placebo
17 Recruiting European Home Mechanical Ventilation Registry
Conditions: Pulmonary Disease, Chronic Obstructive;   Amyotrophic Lateral Sclerosis;   Spinal Cord Injury;   Muscular Dystrophies;   Obesity Hypoventilation Syndrome;   Kyphoscoliosis;   Congenital Central Hypoventilation Syndrome;   Duchenne Muscular Dystrophy;   Myopathies;   Myotonic Dystrophy
Intervention:
18 Completed Postural Spirometry Changes in Ambulatory Myotonic Dystrophy Patients
Condition: Myotonic Dystrophy
Intervention: Other: Supine spirometry
19 Recruiting Variability of Molecular Biomarkers and Clinical Measures in People With Myotonic Dystrophy Type 1
Conditions: Muscle Myopathies;   Muscular Dystrophy;   Inherited Neuromuscular Conditions
Intervention:
20 Recruiting Multicenter Observational Study of Myotonic Dystrophy Type 1
Condition: Myotonic Dystrophy Type 1
Intervention:

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