10 studies found for:    "oculodentodigital dysplasia"
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Rank Status Study
1 Completed
Has Results
A Trial to Evaluate the Safety, Local Tolerability, Pharmacokinetics and Pharmacodynamics of LDE225 on Skin Basal Cell Carcinomas in Gorlin Syndrome Patients
Condition: Treatment for Basal Cell Carcinomas (BCCs) in Gorlin Syndrome Patients
Interventions: Drug: Vehicle;   Drug: LDE225 0.25%;   Drug: LDE225 0.75%
2 Completed
Has Results
Efficacy, Safety and Pharmacokinetics of Oral LDE225 in Treatment of Patients With Nevoid Basal Cell Carcinoma Syndrome (NBCCS)
Conditions: Basal Cell Carcinoma;   Gorlin Syndrome;   Nevoid Basal Cell Carcinoma Syndrome
Interventions: Drug: LDE225;   Drug: Placebo
3 Recruiting Trial of Patidegib Gel 2%, 4%, and Vehicle to Decrease the Number of Surgically Eligible Basal Cell Carcinomas (BCC) in Gorlin Syndrome Patients
Condition: Basal Cell Nevus Syndrome
Interventions: Drug: patidegib;   Drug: vehicle gel
4 Completed To Determine The Efficacy and Safety of GDC-0449 in Patients With Basal Cell Nevus Syndrome (BCNS)
Conditions: Basal Cell Nevus Syndrome;   Gorlin Syndrome
Intervention: Drug: GDC-0449
5 Terminated Two Studies to Determine if Verteporfin PDT is Effective & Safe in Treating Multiple Basal Cell Carcinoma of the Skin.
Conditions: Basal Cell Carcinoma;   Nevoid Basal Cell Carcinoma Syndrome;   Gorlin Syndrome
Intervention: Drug: verteporfin PDT
6 Completed Trial Comparing the Effects of Intermittent Vismodegib vs. PDT in Patients With Multiple Basal Cell Carcinomas
Conditions: Basal Cell Nevus Syndrome;   Gorlin's Syndrome
Interventions: Drug: Vismodegib;   Drug: Aminolevulinic acid %20 topical solution
7 Not yet recruiting Clinical Trial of Patidegib Gel 2%, 4%, and Vehicle Applied Once or Twice Daily to Decrease the Size of Sporadic Nodular Basal Cell Carcinomas
Condition: Basal Cell Carcinomas
Interventions: Drug: patidegib gel 2% - cohort 1;   Drug: patidegib gel 4% - cohort 2;   Drug: Vehicle - cohort 1;   Drug: patidegib gel 2% - cohort 3;   Drug: patidegib gel 4% - cohort 4;   Drug: vehicle - cohort 2;   Drug: Vehicle - cohort 3;   Drug: Vehicle - cohort 4
8 Recruiting Levocarnitine in Treating Patients With Vismodegib-Associated Muscle Spasms
Condition: Musculoskeletal Complications
Interventions: Dietary Supplement: levocarnitine;   Other: placebo;   Other: questionnaire administration
9 Completed A Clinical Trial of Dermacorder for Detecting Malignant Skin Lesions
Condition: Basal Cell Carcinoma
Intervention:
10 Not yet recruiting Blue vs Red Light During Levulan Based Photodynamic Therapy in Patients With Basal Cell Nevus Syndrome
Condition: Basal Cell Nevus Syndrome
Interventions: Drug: Levulan;   Other: Red Light Photodynamic Therapy;   Other: Blue Light Photodynamic Therapy

Indicates status has not been verified in more than two years