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101 studies found for:    "neurofibromatosis type 1"
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Rank Status Study
21 Completed MicroRNAs in Patients With Neurofibromatosis Type 1
Conditions: Glioma;   Neurofibromatosis Type 1
Intervention:
22 Unknown  Analysis of Peripheral Nerve Sheath Tumors (PNSTs) in Neurofibromatosis Type 1 (NF1) Patients
Condition: Neurofibromatosis Type 1
Intervention:
23 Unknown  Ophthalmological Screening and Follow-up of Optic Pathway Gliomas in Children With Neurofibromatosis Type 1.
Condition: Neurofibromatosis Type 1
Intervention:
24 Active, not recruiting
Has Results
AZD2171 in Treating Patients With Neurofibromatosis Type 1 and Plexiform Neurofibroma and/or Neurofibroma Near the Spine
Conditions: Neurofibromatosis Type 1;   Plexiform Neurofibroma;   Spinal Cord Neurofibroma
Intervention: Drug: Cediranib Maleate
25 Not yet recruiting Vitamin D Supplementation for Adults With Neurofibromatosis Type 1 (NF1)
Condition: Neurofibromatosis Type 1 (NF1)
Intervention: Drug: Cholecalciferol
26 Recruiting Selumetinib in Treating Patients With Neurofibromatosis Type 1 and Plexiform Neurofibromas That Cannot Be Removed by Surgery
Conditions: Neurofibromatosis Type 1;   Plexiform Neurofibroma
Interventions: Other: Laboratory Biomarker Analysis;   Other: Pharmacological Study;   Other: Quality-of-Life Assessment;   Drug: Selumetinib
27 Terminated
Has Results
Efficacy and Safety of RAD001 in Treating Plexiform Neurofibromas (PN) Associated With Neurofibromatosis (NF1)
Condition: Plexiform Neurofibroma Associated With Neurofibromatosis Type 1
Intervention: Drug: Everolimus (RAD001)
28 Recruiting Acceptance and Commitment Training for Adolescents and Young Adults With Neurofibromatosis Type 1, Plexiform Neurofibromas, and Chronic Pain
Conditions: Neurofibromatosis Type 1;   Plexiform Neurofibromas
Intervention: Other: Acceptance and Commitment Therapy (ACT)
29 Active, not recruiting Study of Disease Severity in Adults With Neurofibromatosis Type 1 (NF1)
Conditions: Neurofibromatosis Type I;   Legius Syndrome
Intervention:
30 Completed Use of RAD001 as Monotherapy in the Treatment of Neurofibromatosis 1 Related Internal Plexiform Neurofibromas
Conditions: Neurofibromatosis Type 1;   Plexiform Neurofibroma;   Neurofibromatoses
Intervention: Drug: RAD001: Everolimus
31 Completed Reading Disability in Children With NF1
Condition: Neurofibromatosis Type 1
Intervention: Other: Neuropsychological assessments
32 Completed Functional Imaging and Reading Deficit in Children With NF1
Condition: Neurofibromatosis Type 1
Interventions: Other: Neuropsychological assessments;   Radiation: morphological and functional MRI (fMRI);   Genetic: genetic analysis
33 Completed Ranibizumab for Neurofibromas Associated With Neurofibromatosis 1
Conditions: Neurofibromatosis Type 1;   Cutaneous Neurofibromas
Intervention: Drug: Ranibizumab
34 Active, not recruiting MEK Inhibitor PD-0325901 Trial in Adolescents and Adults With NF1
Condition: Neurofibromatosis Type 1 and Growing or Symptomatic, Inoperable PN
Intervention: Drug: PD-0325901
35 Recruiting Targeting the Mechanisms Underlying Cutaneous Neurofibroma Formation in NF1: A Clinical Translational Approach.
Conditions: Cutaneous Neurofibromas;   Neurofibromatosis Type 1;   Plexiform Neurofibromas
Intervention: Procedure: Skin Biopsy
36 Completed Sorafenib to Treat Children and Young Adults With Neurofibromatosis Type 1 and Inoperable Plexiform Neurofibromas
Conditions: Neurofibromatosis Type I;   Plexiform Neurofibroma
Interventions: Drug: Nexavar (BAY 43-9006) (Sorafenib);   Drug: Toxicity, Pharmacokinetics;   Drug: Pharmacodynamics;   Drug: Radiographic Evaluation;   Drug: QOL assessment, Neuropsychological;   Drug: Bony Toxicity
37 Completed
Has Results
R115777 to Treat Children With Neurofibromatosis Type 1 and Progressive Plexiform Neurofibromas
Conditions: Neurofibroma, Plexiform;   Neurofibromatosis Type I
Interventions: Drug: tipifarnib;   Other: placebo
38 Completed
Has Results
Pirfenidone in Children and Young Adults With Neurofibromatosis Type I and Progressive Plexiform Neurofibromas
Conditions: Neurofibromatosis 1;   Neurofibroma, Plexiform
Intervention: Drug: Pirfenidone
39 Completed Combination Chemotherapy in Treating Patients With Stage III or Stage IV Malignant Peripheral Nerve Sheath Tumors
Conditions: Neurofibromatosis Type 1;   Sarcoma
Interventions: Biological: filgrastim;   Drug: doxorubicin hydrochloride;   Drug: etoposide;   Drug: ifosfamide;   Procedure: conventional surgery;   Radiation: radiation therapy
40 Not yet recruiting Subtle Myocardial Deformation Abnormalities in Asymptomatic Nf-1 Patients
Condition: Neurofibromatosis Type 1
Intervention:

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