16 studies found for:    "mitochondrial encephalomyopathy, lactic acidosis, and strokelike episodes" OR "MELAS Syndrome"
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Rank Status Study
1 Completed L-arginine Therapy on Endothelium-dependent Vasodilation & Mitochondrial Metabolism in MELAS Syndrome
Condition: MELAS Syndrome
Intervention: Drug: L-Arginine
2 Unknown  Nitric Oxide Production in MELAS Syndrome
Condition: MELAS Syndrome
Intervention: Dietary Supplement: Arginine and citrulline supplementations
3 Unknown  Evaluating the Effectiveness of a Dichloroacetate in MELAS Syndrome
Condition: MELAS Syndrome
Intervention: Drug: Dichloroacetate
4 Completed Study of the Metabolism of Pyruvate and Related Problems in Patients With Lactic Acidemia
Conditions: Mitochondrial Myopathy;   MELAS Syndrome;   Lactic Acidosis
Intervention:
5 Completed Responses to Influenza Vaccine in Patients With Mitochondrial Disorders (MELAS)
Condition: MELAS Syndrome
Intervention: Biological: Intramuscular seasonal trivalent inactivated influenza vaccine
6 Recruiting Mitochondrial nt3243 A>G Mutation in Taiwan
Conditions: MELAS Syndrome;   Noninsulin-dependent Diabetes Mellitus With Deafness
Intervention:
7 Completed Ketones & Mitochondrial Heteroplasmy
Conditions: MELAS Syndrome;   Mitochondrial Diseases
Intervention: Dietary Supplement: Medium-Chain Triglycerides
8 Unknown  Study of Idebenone in the Treatment of Mitochondrial Encephalopathy Lactic Acidosis & Stroke-like Episodes
Condition: MELAS Syndrome
Interventions: Drug: Idebenone;   Other: Placebo
9 Completed MELA Study - Hedonic Study on the Taste of Drugs Crushed in Food: Observational Study Involving 16 Healthy Volunteers
Condition: Healthy
Interventions: Other: Jelly with:Paracetamol;   Other: Jelly with Furosemide;   Other: Jelly with Levothyroxine sodium salt;   Other: Jelly with Memantine;   Other: Jelly with Zopiclone;   Other: Jelly with Alprazolam;   Other: Jelly with Oxazepam;   Other: Jelly with Donepezil;   Other: Jelly with Clopidogrel;   Other: Jelly with Ramipril;   Other: Jelly with Paracetamol + Furosemide + Levothyroxine sodium salt + Memantine + Zopiclone + Alprazolam;   Other: Plain jelly control;   Other: Apple compote Paracetamol;   Other: Apple compote Furosemide;   Other: Apple compote Levothyroxine sodium salt;   Other: Apple compote Memantine;   Other: Apple compote Zopiclone;   Other: Apple compote Alprazolam;   Other: Apple compote Oxazepam;   Other: Apple compote Donepezil;   Other: Apple compote Clopidogrel;   Other: Apple compote Ramipril;   Other: Apple compote + Paracetamol + Furosemide + Levothyroxine sodium salt + Memantine + Zopiclone + Alprazolam;   Other: Plain apple compote control
10 Recruiting Tissue Sample Study for Mitochondrial Disorders
Conditions: Mitochondrial Disorders;   Mitochondrial Disease;   Melas;   Kearns Sayer;   NARP;   MNGIE;   LHON;   Mitochondrial Depletion Syndrome;   Leigh's Disease
Intervention:
11 Completed A Dose-escalating Clinical Trial With KH176
Conditions: MELAS;   LHON;   Leigh Syndrome;   Mitochondrial Disease;   Mitochondrial DNA tRNALeu(UUR) m.3243A<G Mutation
Interventions: Drug: KH176;   Drug: placebo
12 Recruiting North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)
Conditions: Mitochondrial Disorders;   Mitochondrial Genetic Disorders;   Mitochondrial Diseases;   Disorder of Mitochondrial Respiratory Chain Complexes;   Deletion and Duplication of Mitochondrial DNA
Intervention:
13 Recruiting Natural History Study - Mitochondrial Disease
Condition: m.3243 A>G Mitochondrial DNA Mutation Carrier or Relative
Intervention:
14 Unknown  EPI-743 for Mitochondrial Respiratory Chain Diseases
Condition: Mitochondrial Diseases
Intervention: Drug: EPI-743
15 Enrolling by invitation A Long-Term Extension Study of RP103-MITO-001 to Assess RP103 in Children With Inherited Mitochondrial Disease
Condition: Mitochondrial Diseases
Intervention: Drug: Cysteamine Bitartrate Delayed-release Capsules
16 Enrolling by invitation Open-Label, Dose-Escalating Study to Assess Safety, Tolerability, Efficacy, PK and PD of RP103 in Children With Inherited Mitochondrial Disease
Condition: Inherited Mitochondrial Disease, Including Leigh Syndrome
Intervention: Drug: Cysteamine Bitartrate Delayed-release Capsules (RP103)

Indicates status has not been verified in more than two years