19 studies found for:    "hypophosphatasia"
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Rank Status Study
1 Recruiting Natural History Study of Patients With Hypophosphatasia (HPP)
Condition: Hypophosphatasia
Intervention:
2 Active, not recruiting Extension Study of Protocol ENB-002-08 - Study of Asfotase Alfa in Infants and Young Children With Hypophosphatasia (HPP)
Condition: Hypophosphatasia
Intervention: Biological: asfotase alfa
3 Active, not recruiting Safety and Efficacy Study of Asfotase Alfa in Adolescents and Adults With Hypophosphatasia (HPP)
Condition: Hypophosphatasia
Intervention: Drug: asfotase alfa
4 Recruiting Open-Label Study of Asfotase Alfa in Infants and Children ≤ 5 Years of Age With Hypophosphatasia (HPP)
Condition: Hypophosphatasia
Intervention: Drug: asfotase alfa
5 Completed
Has Results
Retrospective, Non-interventional Natural History of Patients With Juvenile-onset Hypophosphatasia (HPP)
Condition: Hypophosphatasia (HPP)
Intervention:
6 Completed Dose Escalation Study to Evaluate the Safety and Tolerability of Multiple Infusions of BPS804 in Adults With Hypophosphatasia (HPP)
Condition: Hypophosphatasia
Intervention: Drug: BPS804
7 Completed
Has Results
A Retrospective Study of the Natural History of Patients With Severe Perinatal and Infantile Hypophosphatasia (HPP)
Condition: Hypophosphatasia (HPP)
Intervention:
8 Active, not recruiting Extension Study of Protocol ENB-006-09 - Study of Asfotase Alfa in Children With Hypophosphatasia (HPP)
Condition: Hypophosphatasia (HPP)
Intervention: Biological: Asfotase Alfa
9 Completed
Has Results
Safety and Efficacy of Asfotase Alfa in Juvenile Patients With Hypophosphatasia (HPP)
Condition: Hypophosphatasia (HPP)
Intervention: Biological: asfotase alfa
10 Completed
Has Results
Safety and Efficacy Study of Asfotase Alfa in Severely Affected Infants With Hypophosphatasia (HPP)
Condition: Hypophosphatasia (HPP)
Intervention: Biological: asfotase alfa
11 Completed Safety Study of Human Recombinant Tissue Non-Specific Alkaline Phosphatase Fusion Protein Asfotase Alfa in Adults With Hypophosphatasia (HPP)
Condition: Hypophosphatasia (HPP)
Intervention: Biological: Asfotase Alfa
12 Recruiting Biomarker for Hypophosphatasia Disease
Conditions: HEREDITARY DISEASES;   METABOLISM, INBORN ERRORS;   Hypophosphatasia
Intervention:
13 Enrolling by invitation Safety and Efficacy of Asfotase Alfa in Patients With Hypophosphatasia (HPP)
Condition: Hypophosphatasia
Intervention: Drug: Asfotase Alfa (ALXN1215)
14 Withdrawn Safety and Efficacy Study of ENB-0040 in Juvenile Patients With Hypophosphatasia (HPP)
Condition: Hypophosphatasia
Intervention: Biological: ENB-0040
15 Active, not recruiting Post-approval Clinical Study of Asfotase Alfa Treatment for Patients With Hypophosphatasia (HPP) in Japan
Condition: Hypophosphatasia
Intervention: Biological: Asfotase Alfa
16 Enrolling by invitation An Observational, Longitudinal, Prospective, Long-Term Registry Of Patients With Hypophosphatasia (HPP)
Condition: Hypophosphatasia (HPP)
Intervention:
17 Approved for marketing Expanded Access Program for Asfotase Alfa Treatment for Patients With Infantile- or Juvenile-onset Hypophosphatasia (HPP)
Condition: Hypophosphatasia
Intervention: Biological: asfotase alfa
18 Recruiting Burden of Disease in Hypophosphatasia (HPP)
Condition: Hypophosphatasia
Intervention:
19 Completed
Has Results
Non-interventional Substudy of ALX-HPP-502 to Assess Natural History of Patients With Juvenile-onset HPP Who Served as Historical Controls in ENB-006-09
Conditions: Hypophosphatasia;   Bone Disease
Intervention: Biological: Retrospective Case Only

Indicates status has not been verified in more than two years