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133 studies found for:    "familial hypercholesterolemia"
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Rank Status Study
21 Unknown  Evaluation of Chylomicrons Metabolism in Sub-Clinical Atherosclerosis in Patients Whit Heterozigous Familial Hypercholesterolemia (FH) Treated With Statin Plus Ezetimibe
Condition: Heterozigous Familial Hypercholesterolemia
Intervention: Drug: Statins and Ezetimibe
22 Not yet recruiting HDL Acute Lipid Optimization in Homozygous Familial Hypercholesterolemia
Condition: Homozygous Familial Hypercholesterolemia
Intervention: Device: HDL Therapeutics PDS-2 System
23 Completed
Has Results
Gene Analysis and Treatment Optimization in Chinese Homozygous Familial Hypercholesterolemia
Condition: Homozygous Familial Hypercholesterolemia
Interventions: Genetic: Gene analysis;   Other: Historical data of lipid-lowering drug administration;   Other: Historical data of plasma lipids, xanthoma changes
24 Recruiting A Gene Therapy Study for Homozygous Familial Hypercholesterolemia (HoFH)
Condition: Homozygous Familial Hypercholesterolemia
Intervention: Biological: AAV directed hLDLR gene therapy
25 Recruiting A Study of ALN-PCSSC in Participants With Homozygous Familial Hypercholesterolemia
Condition: Homozygous Familial Hypercholesterolemia
Interventions: Drug: ALN-PCSSC;   Drug: Standard of Care
26 Recruiting Study of MGL-3196 in Patients With Heterozygous Familial Hypercholesterolemia (HeFH)
Condition: Heterozygous Familial Hypercholesterolemia
Interventions: Drug: MGL-3196;   Drug: Placebo
27 Completed Comparisons of Two Low-density Lipoprotein Apheresis Systems in Patients With Homozygous Familial Hypercholesterolemia
Condition: Homozygous Familial Hypercholesterolemia
Interventions: Device: heparin-induced extracorporeal LDL precipitation;   Device: dextran sulfate adsorption
28 Active, not recruiting Study of REGN1500 in Patients With Homozygous Familial Hypercholesterolemia (HoFH)
Condition: Homozygous Familial Hypercholesterolemia
Intervention: Drug: REGN1500
29 Not yet recruiting Study in Participants ≥12 Years of Age With Homozygous Familial Hypercholesterolemia (hoFH)
Condition: Homozygous Familial Hypercholesterolemia
Interventions: Drug: Alirocumab;   Drug: Placebo
30 Completed
Has Results
A Safety and Efficacy Study of AEGR-733 to Treat Homozygous Familial Hypercholesterolemia (FH)
Condition: Homozygous Familial Hypercholesterolemia
Intervention: Drug: AEGR-733
31 Withdrawn Evaluate the Efficacy and Safety of Lomitapide in Pediatric Patients With Homozygous Familial Hypercholesterolemia on Stable Lipid-lowering Therapy
Condition: Homozygous Familial Hypercholesterolemia
Intervention: Drug: Lomitapide
32 Completed Study of Alirocumab (REGN727/SAR236553) in Patients With Heterozygous Familial Hypercholesterolemia (HeFH) Undergoing Low-density Lipoprotein (LDL) Apheresis Therapy
Condition: Heterozygous Familial Hypercholesterolemia
Interventions: Drug: Alirocumab;   Drug: Placebo
33 Completed
Has Results
Study of Alirocumab (REGN727/SAR236553) in Patients With heFH (Heterozygous Familial Hypercholesterolemia) Who Are Not Adequately Controlled With Their LMT (Lipid-Modifying Therapy)
Condition: Heterozygous Familial Hypercholesterolemia
Interventions: Drug: LMT (atorvastatin, simvastatin, or rosuvastatin);   Drug: alirocumab;   Drug: Placebo
34 Recruiting Familial Hypercholesterolemia Canada / Hypercholesterolemie Familiale Canada
Conditions: Familial Hypercholesterolemia;   Lipid Disorder
Intervention:
35 Recruiting Familial Hypercholesterolemia in Turkey (A-HIT2)
Conditions: Familial Hypercholesterolemia;   Atherosclerosis
Intervention:
36 Completed Efficacy and Safety of Fluvastatin in Children With Heterozygous Familial Hypercholesterolemia
Conditions: Heterozygous Familial Hypercholesterolemia;   Mixed Dyslipidemia
Intervention: Drug: Fluvastatin
37 Completed
Has Results
A Study to Evaluate the Efficacy and Safety of Rosuvastatin in Children and Adolescents With Homozygous Familial Hypercholesterolemia
Condition: Homozygous Familial Hypercholesterolemia (HoFH)
Interventions: Drug: Rosuvastatin 20mg;   Drug: Placebo
38 Completed A Study to Evaluate the Safety of Rosuvastatin in Children and Adolescents With Homozygous Familial Hypercholesterolemia
Condition: Homozygous Familial Hypercholesterolemia (HoFH)
Intervention: Drug: Rosuvastatin 20mg
39 Completed A Study of the Safety and Efficacy of Anacetrapib (MK-0859) When Added to Ongoing Statin Therapy in Japanese Participants With Heterozygous Familial Hypercholesterolemia (MK-0859-050)
Condition: Heterozygous Familial Hypercholesterolemia (HeFH)
Interventions: Drug: Anacetrapib;   Drug: Placebo for anacetrapib
40 Unknown  Postprandial Lipid Metabolism in Familial Hypercholesterolaemia:Effects of Fish Oils
Conditions: Hypertriglyceridaemia;   Familial Hypercholesterolaemia
Interventions: Dietary Supplement: Fish oil capsule;   Drug: HMG Coenzyme reductase

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Study has passed its completion date and status has not been verified in more than two years.