119 studies found for:    "familial hypercholesterolemia"
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Rank Status Study
21 Recruiting Developing and Implementing Familial Hypercholesterolemia Registry
Condition: Familial Hypercholesterolemia
Intervention: Other: Cascade
22 Completed Efficacy of a New Symbiotic Formulation in Children With Familial Hypercholesterolemia
Conditions: Dyslipidemia;   Familial Hypercholesterolemia
Interventions: Dietary Supplement: Lactobacillus paracasei B21060;   Other: low satured diet
23 Not yet recruiting Pediatric Population Screening for Type 1 Diabetes and Familial Hypercholesterolemia in Lower Saxony, Germany
Conditions: Type 1 Diabetes;   Familial Hypercholesterolemia
Intervention:
24 Completed Relationships Between Plasma PCSK9 Levels, LDL-cholesterol Concentrations and Lipoprotein (a) Levels in Familial Hypercholesterolemia
Condition: Familial Hypercholesterolemia
Intervention:
25 Completed A Study of the Safety and Efficacy of Patients With Familial Hypercholesterolaemia Taking Colesevelam as add-on Therapy to Their Existing Medication
Condition: Familial Hypercholesterolemia
Interventions: Drug: Colesevelam hydrochloride film-coated tablets;   Drug: Placebo
26 Completed Effects of LDL Apheresis System on the Expression of Genes Involved in Lipoprotein Metabolism and Inflammation in Homozygotes for Familial Hypercholesterolemia
Condition: Familial Hypercholesterolemia
Interventions: Other: Pre-lipid apheresis;   Other: Post-lipid apheresis
27 Unknown  Gene Analysis and Treatment Optimization in Chinese Homozygous Familial Hypercholesterolemia
Condition: Homozygous Familial Hypercholesterolemia
Intervention: Other: Gene analysis
28 Recruiting Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IONIS ANGPTL3-LRx in Healthy Volunteers With Elevated Triglycerides and Subjects With Familial Hypercholesterolemia
Conditions: Hypertriglyceridemia;   Familial Hypercholesterolemia
Interventions: Drug: IONIS ANGPTL3-LRx;   Drug: Placebo (0.9%NaCl, water, riboflavin)
29 Recruiting A Gene Therapy Study for Homozygous Familial Hypercholesterolemia (HoFH)
Condition: Homozygous Familial Hypercholesterolemia
Intervention: Genetic: AAV directed hLDLR gene therapy
30 Completed Comparisons of Two Low-density Lipoprotein Apheresis Systems in Patients With Homozygous Familial Hypercholesterolemia
Condition: Homozygous Familial Hypercholesterolemia
Interventions: Device: heparin-induced extracorporeal LDL precipitation;   Device: dextran sulfate adsorption
31 Recruiting Study of REGN1500 in Patients With Homozygous Familial Hypercholesterolemia (HoFH)
Condition: Homozygous Familial Hypercholesterolemia
Intervention: Drug: REGN1500
32 Completed
Has Results
A Safety and Efficacy Study of AEGR-733 to Treat Homozygous Familial Hypercholesterolemia (FH)
Condition: Homozygous Familial Hypercholesterolemia
Intervention: Drug: AEGR-733
33 Terminated
Has Results
A Study of Extended-release (ER) Niacin/Laropiprant in Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0524A-158)
Conditions: Hypercholesterolemia, Familial;   Heterozygous Familial Hypercholesterolemia
Intervention: Drug: MK-0524A
34 Not yet recruiting Evaluate the Efficacy and Safety of Lomitapide in Pediatric Patients With Homozygous Familial Hypercholesterolemia on Stable Lipid-lowering Therapy
Condition: Homozygous Familial Hypercholesterolemia
Intervention: Drug: Lomitapide
35 Completed
Has Results
A Study to Evaluate the Efficacy and Safety of Rosuvastatin in Children and Adolescents With Homozygous Familial Hypercholesterolemia
Condition: Homozygous Familial Hypercholesterolemia (HoFH)
Interventions: Drug: Rosuvastatin 20mg;   Drug: Placebo
36 Active, not recruiting Study of Alirocumab (REGN727/SAR236553) in Patients With Heterozygous Familial Hypercholesterolemia (HeFH) Undergoing Low-density Lipoprotein (LDL) Apheresis Therapy
Condition: Heterozygous Familial Hypercholesterolemia
Interventions: Drug: Alirocumab;   Drug: Placebo
37 Active, not recruiting A Study to Evaluate the Safety of Rosuvastatin in Children and Adolescents With Homozygous Familial Hypercholesterolemia
Condition: Homozygous Familial Hypercholesterolemia (HoFH)
Intervention: Drug: Rosuvastatin 20mg
38 Terminated Efficacy and Tolerability of Anacetrapib Added to Ongoing Lipid-Lowering Therapy in Adult Participants With Homozygous Familial Hypercholesterolemia (HoFH) (MK-0859-042)
Conditions: Hyperlipoproteinemia Type II;   Homozygous Familial Hypercholesterolemia
Interventions: Drug: Anacetrapib;   Drug: Placebo
39 Completed
Has Results
Study of Alirocumab (REGN727/SAR236553) in Patients With heFH (Heterozygous Familial Hypercholesterolemia) Who Are Not Adequately Controlled With Their LMT (Lipid-Modifying Therapy)
Condition: Heterozygous Familial Hypercholesterolemia
Interventions: Drug: LMT (atorvastatin, simvastatin, or rosuvastatin);   Drug: alirocumab;   Drug: Placebo
40 Active, not recruiting Study to Assess the Tolerability and Efficacy of Anacetrapib Co-administered With Statin in Participants With Heterozygous Familial Hypercholesterolemia (MK-0859-020)
Conditions: Hyperlipoproteinemia Type II;   Heterozygous Familial Hypercholesterolemia
Interventions: Drug: Anacetrapib;   Drug: Placebo for Anacetrapib

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Indicates status has not been verified in more than two years