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146 studies found for:    "beta thalassemia"

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Rank Status Study
1 Completed Iron Balance Study of DFO and GT56-252 in Patients With Transfusional Iron Overload Secondary to Beta-Thalassemia
Condition: Beta-Thalassemia
Interventions: Drug: Deferitrin (GT56-252);   Drug: desferoxamine (DFO)
2 Recruiting Gene Therapy for Transfusion Dependent Beta-thalassemia
Condition: Beta-Thalassemia
Intervention: Genetic: Autologous hematopoietic stem cells genetically modified with GLOBE lentiviral vector encoding for the human beta-globin gene
3 Completed Evaluating the Safety of G-CSF Mobilization in Individuals With Beta Thalassemia Major
Condition: Beta-Thalassemia
Intervention: Drug: Hydroxyurea
4 Completed Evaluating the Safety and Effectiveness of Mozobil Mobilization in Adults With Beta-Thalassemia Major
Condition: Beta-Thalassemia
Intervention: Drug: Mozobil
5 Completed Trial of HQK-1001 in Beta Thalassemia Intermedia in Lebanon
Condition: Beta Thalassemia Intermedia
Intervention: Drug: Sodium 2,2 dimethylbutyrate
6 Completed To Document the Burden of Illness on the Quality of Life and the Impact on Healthcare Utilization in (Beta) β-thalassemia Subjects Who Are Transfusion Dependent (TD) and Non-transfusion Dependent (NTD) Receiving Standard of Care
Condition: Beta-Thalassemia
Interventions: Other: Quality of Life (QOL) questionnaires;   Other: Healthcare Resource Utilization
7 Unknown † Genetic Factors Affecting the Severity of Beta Thalassemia
Condition: Beta Thalassemia
Intervention:
8 Active, not recruiting ACE-536 Extension Study - Beta Thalassemia
Condition: Beta-Thalassemia
Intervention: Drug: ACE-536
9 Not yet recruiting A Study of EPEG in Beta Thalassemia Patients
Condition: Beta-Thalassemia
Intervention: Drug: EPEG (Pegylated erythropoeitin)
10 Active, not recruiting Effects of Spirulina on Cardiac Functions in Children With Beta Thalassemia Major
Condition: Beta Thalassemia
Intervention: Other: spirulina
11 Active, not recruiting A Study Evaluating the Safety and Efficacy of the LentiGlobin® BB305 Drug Product in Beta-Thalassemia Major Subjects
Condition: Beta-thalassemia Major
Intervention: Genetic: LentiGlobin® BB305 Drug Product
12 Completed Phase 1/2 Study of HQK-1001 in Patients With Beta Thalassemia
Condition: Beta Thalassemia
Interventions: Drug: HQK-1001;   Drug: Placebo
13 Recruiting A Study Evaluating the Efficacy and Safety of the LentiGlobin® BB305 Drug Product in Subjects With Transfusion-Dependent β-Thalassemia
Condition: Beta-Thalassemia
Intervention: Genetic: LentiGlobin BB305 Drug Product
14 Unknown † An Algorithm to Start Iron Chelation in Minimally Transfused Young Beta-thalassemia Major Patients
Condition: Beta Thalassemia Major
Intervention: Drug: Deferiprone
15 Completed Study of SDMB (2,2 Dimethylbutyrate, Sodium Salt) in Beta Thalassemia Intermedia in Thailand
Condition: Beta Thalassemia Intermedia
Intervention: Drug: sodium 2,2 dimethylbutyrate
16 Recruiting Monitoring of Chimerism After Transplantation in Patients With β Thalassemia Major and the Treatment Strategies for the Reduction of Chimerism
Condition: Beta Thalassemia Major
Interventions: Drug: Interleukin-2;   Drug: Donor Regulatory T-Lymphocytes
17 Withdrawn An Open Label Study to Evaluate the Pharmacokinetics, Safety, Tolerability and Efficacy of Deferasirox Administered to Chinese Patients With β-thalassemia Major Aged From 2 to Less Than 6 Years Old
Condition: β-thalassemia Major
Intervention: Drug: Deferasirox
18 Completed Combination Therapy of Hydroxyurea With L-Carnitine and Magnesium Chloride in Thalassemia Intermedia
Condition: β-Thalassemia Intermedia
Interventions: Drug: hydroxyurea;   Drug: L-carnitine and hydroxyurea;   Drug: hydroxyurea and magnesium chloride;   Drug: hydroxyurea,L-carnitine and magnesium chloride
19 Active, not recruiting Effect of Spirulina Compared to Amlodipine on Cardiac Iron Overload in Children With Beta Thalassemia
Condition: Beta Thalassemia Major
Interventions: Drug: Spirulina;   Drug: Amlodipine
20 Recruiting Efficacy of Basiliximab in the Prevention of Acute Graft-versus-host Disease in Unrelated Allogeneic Hematopoietic Stem Cell Transplantation Therapy for Thalassemia Major
Condition: Beta-Thalassemia Major
Interventions: Drug: Basiliximab,;   Drug: cyclosporine A;   Drug: Methotrexate;   Drug: Mycophenolate mofetil
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† Study has passed its completion date and status has not been verified in more than two years.