37 studies found for:    "WHIMS"
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1 Recruiting A Phase I Study of Mozobil in the Treatment of Patients With WHIMS
Conditions: WHIMS;   Neutrophil Disorder;   Myelokathexis;   Hypogammaglobulinemia
Intervention: Drug: Mozobil (TM)
2 Recruiting Plerixafor Versus G-CSF in the Treatment of People With WHIM Syndrome
Conditions: Myelokathexis;   WHIMS;   Neutropenia;   Warts
Interventions: Drug: Plerixafor;   Drug: G-CSF
3 Completed Evaluating the Effects of Hormone Replacement Therapy on Brain Function (The WHIMS-MRI Study)
Condition: Stroke
Intervention:
4 Completed Safety Study of a Chemokine Receptor (CXCR4) Antagonist in Multiple Myeloma Patients
Condition: Multiple Myeloma
Intervention: Drug: BKT140
5 Not yet recruiting Imatinib and BL-8040 (Novel Anti CXCR4 Antagonist) for Improving Molecular Response in Chronic Myelogenous Leukemia
Condition: Chronic Myeloid Leukemia
Intervention: Drug: BL-8040
6 Completed CXCR4 Antagonism for Cell Mobilisation and Healing in Acute Myocardial Infarction (CATCH-AMI)
Condition: Large Reperfused ST-Elevation Myocardial Infarction
Interventions: Drug: POL6326;   Drug: Placebo
7 Suspended Imaging CXCR4 Expression in Subjects With Cancer Using 64 Cu-Plerixafor
Condition: Cancer
Intervention: Drug: 64-Cu-plerixafor
8 Completed The Women's Health Initiative Memory Study (The WHIMS Study)
Condition: Dementia Syndromes
Interventions: Drug: Estrogen hormone therapy;   Drug: Estrogen plus progesterone hormone therapy;   Drug: Placebo
9 Completed A Trial to Establish the Feasibility of Combining Either the Tyrosine Kinase Inhibitor AC220,CXCR4 Inhibitor Plerixafor or HSP90 Inhibitor Ganetespib With Chemotherapy in Older Patients With Acute Myeloid Leukaemia and High Risk Myelodysplastic Syndrome.
Conditions: Acute Myeloid Leukaemia;   High Risk Myelodysplastic Syndrome
Interventions: Drug: Plerixafor;   Drug: AC220;   Drug: Ganetespib
10 Completed
Has Results
AMD 3100 for Treatment of Myelokathexis
Condition: Neutropenia
Intervention: Drug: AMD3100 or plerixafor
11 Recruiting Correlation of CXCR4 Expression in Premature Infants With a Diagnosis of Autism at 24 Months
Conditions: Autism Spectrum Disorder;   Complication of Prematurity
Intervention:
12 Unknown  The Role of SDF-1/CXCR4 in Metastasis of Oral Squamous Cell Carcinoma
Condition: Oral Cancer
Intervention:
13 Unknown  The Role of Stromal Cell-Derived Factor-1 (SDF-1)/CXC Chemokine Receptor 4 (CXCR4) in Metastasis of Laryngeal and Hypopharyngeal Squamous Cell Carcinoma
Conditions: Laryngeal Cancer;   Hypopharyngeal Cancer;   Metastasis
Intervention:
14 Completed Auto-immunity in Lupus Patients After Influenza Vaccine
Condition: Systemic Lupus Erythematosus (SLE)
Intervention: Drug: Vaccine
15 Completed Natural History of Human Papillomavirus (HPV) Infections in Mid-Adult Women (WHIM)
Condition: Papillomavirus Infections
Intervention:
16 Completed Safety and Activity of the Oral HIV Entry Inhibitor AMD11070 in HIV Infected Patients
Condition: HIV Infections
Intervention: Drug: AMD11070
17 Active, not recruiting Examining the Relationship Between Hormone Therapy and Cognitive Function (The WHIMS-ECHO Study)
Condition: Dementia
Intervention:
18 Completed Anti-CXCR4 (BMS-936564) Alone and in Combination With Lenalidomide/Dexamethasone or Bortezomib/Dexamethasone in Relapsed/Refractory Multiple Myeloma
Condition: Multiple Myeloma
Interventions: Biological: Anti-CXCR4 (BMS-936564);   Biological: Lenalidomide;   Biological: Dexamethasone;   Biological: Bortezomib
19 Terminated First in Man Study of ALX-0651, a Nanobody Inhibiting CXCR4
Condition: Healthy Volunteers
Interventions: Biological: ALX-0651;   Biological: Placebo
20 Unknown  Studies on the Significance of CXCR4-CXCL12 on Leukemic Cells Passing Through"Marrow-Blood Barrier"
Conditions: Acute Myelocytic Leukemia;   Acute Lymphocytic Leukemia
Intervention:

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Indicates status has not been verified in more than two years