214 studies found for:    "Thalassemia"
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1 Completed Thalassemia (Cooley's Anemia) Clinical Research Network (TCRN)
Conditions: Anemia, Cooley's;   Beta-Thalassemia;   Hematologic Diseases;   Thalassemia;   Osteoporosis;   Iron Overload;   Hypertension, Pulmonary
Interventions: Drug: Deferoxamine;   Drug: Deferiprone;   Drug: Arginine;   Drug: Sildenafil;   Drug: Decitabine
2 Unknown  Prevalence of Pulmonary Hypertension (PAH) in Patients With Thalassemia
Conditions: Thalassemia Major;   Thalassemia Intermedia;   Pulmonary Arterial Hypertension
Intervention: Other: Physician standard-of-care according to ESC/ERS Guidelines
3 Recruiting Study to Determine the Safety and Tolerability of Sotatercept (ACE-011) in Adults With Beta( β)- Thalassemia.
Conditions: Beta Thalassemia Major;   Beta Thalassemia Intermedia
Interventions: Drug: Dose level 1a;   Drug: Dose level 1b;   Drug: Dose level 2;   Drug: dose level 3;   Drug: dose level 4;   Drug: dose level 5
4 Completed Beta-thalassemia and Microparticles
Conditions: Thalassemia Major (TM);   Thalassemia Intermedia (TI);   Microparticles (MP)Originating From Platelets, Endothelial Cells and Monocytes
Intervention: Other: Physiopathology
5 Completed 5-Azacytidine and Phenylbutyrate to Treat Severe Thalassemia
Condition: Beta Thalassemia
Intervention: Drug: 5-Azacytidine
6 Recruiting Reproductive Capacity and Iron Burden in Thalassemia
Condition: THALASSEMIA MAJOR
Interventions: Other: Blood Draw/Semen Exam;   Other: Retrospective data/Chart Review/Relevant Clinical Results;   Other: Pituitary MRI
7 Completed Effect of Antioxidant Cocktail in Beta-thalassemia/Hb E Patients
Condition: Thalassemia
Interventions: Drug: curcuminoids, N-acetylcysteine, deferiprone and vitamin E;   Drug: Curcuminoids and alpha-tocopherol
8 Completed Perceptions of Thalassemia Major in Singapore: An Exploratory Study of Stigma
Condition: Thalassemia Major
Intervention:
9 Recruiting Endocrine and Nutritional Assessment in B Thalassemia Major
Condition: Thalassemia
Intervention: Other: Nutritional recommendations
10 Recruiting Detection of β Thalassemia Carriers by Red Cell Parameters Obtained From the H2 Automatic Counter
Conditions: Thalassemia;   Iron Deficiency
Intervention: Procedure: Observation of results from laboratory tests
11 Completed A Study of Long-term Treatment With Deferasirox in Patients With Beta-thalassemia and Transfusional Hemosiderosis
Conditions: Beta-Thalassemia;   Hemosiderosis
Intervention: Drug: deferasirox
12 Active, not recruiting Amlodipine in the Prevention and Treatment of Iron Overload in Patients With Thalassemia Major
Conditions: Thalassemia;   Iron Overload
Intervention: Drug: Amlodipine
13 Completed
Has Results
Evaluating the Safety and Effectiveness of Decitabine in People With Thalassemia Intermedia
Condition: Thalassemia
Intervention: Drug: Decitabine (USAN, INN)
14 Unknown  The Effect of Vitamin D Supplementation on Calcium Excretion in Thalassemia: a Dose Response Study
Condition: Thalassemia Major
Interventions: Drug: Vitamin D3;   Drug: Placebo
15 Recruiting Haploidentical Hematopoietic Stem Cell Transplantation for Children With Sickle Cell Disease and Thalassemia Using CD34+ Positive Selected Grafts
Conditions: Sickle Cell-thalassemia Disease;   Thalassemia
Intervention: Drug: peripheral blood stem cell graft that are CD34+ selected
16 Completed Amlodipine Use in the Prevention and Treatment of Iron Overload in Patients With Thalassemia Major
Condition: Thalassemia Major
Intervention: Drug: Amlodipine
17 Recruiting Iron Overload and Growth Velocity in Thalassemia and Sickle Cell Anemia
Conditions: Thalassemia;   Sickle Cell Disease
Intervention: Other: Medical Chart Summary
18 Completed The Change of Coagulation Markers in Children With β-thalassemia Disease After Stem Cell Transplantation
Condition: Thalassemia
Intervention:
19 Recruiting Stem Cell Transplant in Sickle Cell Disease and Thalassemia
Conditions: Sickle Cell Disease;   Beta Thalassemia
Interventions: Drug: Busulfan;   Drug: Fludarabine;   Drug: Alemtuzumab;   Procedure: Allogeneic stem cell transplant
20 Recruiting Study of Efficacy and Safety of INC424 in Regularly Transfused Patients With Thalassemia.
Condition: Thalassemia Major
Intervention: Drug: INC424 (ruxolitinib)

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Indicates status has not been verified in more than two years