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31 studies found for:    "Sialorrhea"
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Rank Status Study
1 Completed Efficacy and Safety Study of MYOBLOC® Followed by Open-Label Multiple-Treatment With MYOBLOC® in the Treatment of Troublesome Sialorrhea in Adult Subjects
Condition: Sialorrhea
Interventions: Drug: MYOBLOC;   Other: PLACEBO
2 Completed Botulinum Toxin-A for Sialorrhoea Treatment in Asian Adults With Neurological Diseases
Condition: Sialorrhea
Interventions: Drug: Botulinum toxin A (BoNT-A) 50U;   Drug: Botulinum toxin A (BoNT-A) 100U;   Drug: Botulinum toxin A (BoNT-A) 200U
3 Active, not recruiting Open-Label and Single-Arm Study of MYOBLOC® in the Treatment of Troublesome Sialorrhea in Adults
Condition: Sialorrhea
Intervention: Drug: MYOBLOC
4 Completed A Relative Efficacy and Safety Study of OC Oral Solution for Sialorrhoea in Patients With Parkinson's Disease
Condition: Sialorrhoea
Interventions: Drug: OC oral solution treatment A;   Drug: OC oral solution treatment B;   Drug: OC oral solution treatment C;   Drug: OC oral solution treatment D
5 Not yet recruiting Clozapine-induced Hypersalivation - Feasibility Trial
Condition: Sialorrhea
Interventions: Drug: Hyoscine;   Drug: Glycopyrrolate;   Other: Placebo
6 Completed
Has Results
Safety and Efficacy Study of NH004 Films for Relief of Sialorrhea Symptoms in Parkinson's Disease Patients
Condition: Sialorrhea Secondary to Parkinson's Disease
Interventions: Drug: 0.3 mg tropicamide;   Drug: 1 mg tropicamide;   Drug: 3 mg tropicamide;   Drug: 0 mg tropicamide
7 Completed
Has Results
Effectiveness of Atropine and Glycopyrrolate to Reduce Hyper Salivation With Ketamine Sedation
Condition: Sialorrhea
Interventions: Drug: Atropine (0.01mg/kg);   Drug: Glycopyrrolate (0.01mg/kg);   Drug: Normal saline 0.9%
8 Completed
Has Results
Incobotulinum Toxin A (Xeomin®) for Troublesome Sialorrhea in Parkinson's Disease (PD)/Parkinsonism
Condition: Sialorrhea
Interventions: Drug: Incobotulinum Toxin A;   Drug: Placebo
9 Recruiting Study of Glycopyrrolate for Moderate-to-severe Sialorrhea in Parkinson's Disease
Conditions: Sialorrhea;   Parkinson's Disease
Interventions: Drug: Glycopyrrolate;   Drug: Placebo
10 Completed Study of the Safety and Efficacy of Tropicamide Thin Films to Reduce Hypersalivation in Parkinson's Patients
Condition: Sialorrhea (Excessive Drooling)
Interventions: Drug: NH004 tropicamide;   Drug: NH004 Placebo
11 Completed Toxin Treatment for Amyotrophic Lateral Sclerosis (ALS) Related Sialorrhea
Conditions: Sialorrhea;   Amyotrophic Lateral Sclerosis
Interventions: Drug: Botox injection;   Drug: Placebo injection
12 Completed Treatment of Clozapine-Induced Hypersalivation Ipratropium Bromide
Condition: Hypersalivation
Intervention: Drug: ipratropium bromide 0.03% spray
13 Completed Study of Myobloc in the Treatment of Sialorrhea (Drooling) in Patients With Amyotrophic Lateral Sclerosis (ALS)
Conditions: Amyotrophic Lateral Sclerosis;   Sialorrhea
Interventions: Drug: Botulinum toxin type B (Myobloc);   Procedure: Injection of salivary glands
14 Completed Metoclopramide as Treatment of Clozapine-induced Hypersalivation
Condition: Clozapine-induced Hypersalivation
Interventions: Drug: Metoclopramide;   Drug: placebo
15 Completed Benzamide Derivates as Treatment of Clozapine-induced Hypersalivation
Condition: Clozapine-induced Hypersalivation
Intervention: Drug: Amisulpride, Moclobemide
16 Completed
Has Results
A Multi-Center Study of MYOBLOC for the Treatment of Sialorrhea in Parkinson's Disease Patients
Condition: Drooling
Interventions: Biological: Botulinum Toxin Type B (Myobloc);   Biological: Matched placebo to Myobloc
17 Completed Clinical Study to Investigate the Efficacy and Safety of Two Dose Levels of NT 201 Versus Placebo in Treating Chronic Troublesome Sialorrhea in Various Neurological Conditions
Conditions: Chronic Troublesome Sialorrhea;   Parkinson's Disease;   Post-stroke;   Traumatic Brain Injury
Interventions: Drug: IncobotulinumtoxinA (100 Units);   Drug: IncobotulinumtoxinA (75 Units);   Drug: Placebo
18 Unknown  The Treatment of 2 Chinese Medicines in Clozapine-induced Hypersalivation in Schizophrenia
Conditions: Schizophrenia;   Clozapine;   Hypersalivation;   Traditional Chinese Medicine
Interventions: Drug: Suo Quan Wan, Wu Lin San;   Drug: Placebo
19 Completed FazaClo Outcomes in the Control of Schizophrenia (FOCUS) Study Survey
Conditions: Weight Gain;   Sialorrhea
Intervention: Drug: FazaClo (clozapine, USP) ODT
20 Unknown  Application of Botulinum Toxin Type A in Salivary Glands in the Treatment of Drooling in Patients With Cerebral Palsy
Conditions: Sialorrhea;   Cerebral Palsy
Intervention: Biological: BOTULINUM NEUROTOXIN TYPE-A

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Study has passed its completion date and status has not been verified in more than two years.