267 studies found for:    "Scleroderma, Systemic"
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Rank Status Study
21 Recruiting Proof-of-concept Trial of IVA337 in Diffuse Cutaneous Systemic Sclerosis
Conditions: Scleroderma, Diffuse;   Diffuse Cutaneous Systemic Sclerosis
Interventions: Drug: IVA337;   Drug: Placebo
22 Recruiting Cyclophosphamide Systemic Sclerosis Associated Interstitial Lung Disease
Conditions: Systemic Sclerosis;   Scleroderma;   Interstitial Lung Disease;   Lung Fibrosis
Interventions: Drug: Cyclophosphamide;   Drug: Placebo
23 Recruiting Allogeneic Hematopoietic Cell Transplantation After Nonmyeloablative Conditioning for Patients With Severe Systemic Sclerosis
Conditions: Systemic Scleroderma;   Severe Systemic Sclerosis
Interventions: Drug: fludarabine phosphate;   Drug: Mycophenolic Acid;   Drug: tacrolimus;   Radiation: total-body irradiation;   Procedure: bone marrow transplantation;   Procedure: reduced intensity allogeneic hematopoietic stem cell transplantation;   Procedure: quality-of-life assessment;   Other: laboratory biomarker analysis;   Other: flow cytometry;   Procedure: biopsy;   Drug: cyclophosphamide
24 Recruiting IL1-TRAP, Rilonacept, in Systemic Sclerosis
Conditions: Scleroderma;   Systemic Sclerosis;   Diffuse Scleroderma;   Diffuse Systemic Sclerosis
Interventions: Drug: Rilonacept;   Drug: Placebo
25 Recruiting Scleroderma Registry
Conditions: Systemic Sclerosis;   Scleroderma
Intervention:
26 Completed SCOT Scleroderma Treatment Alternative Registry (STAR Registry)
Conditions: Scleroderma, Systemic;   Sclerosis
Intervention: Drug: currently available therapy in the community
27 Completed
Has Results
Imatinib in Systemic Sclerosis
Condition: Scleroderma, Systemic
Intervention: Drug: Imatinib mesylate
28 Recruiting Scleroderma Registry & Repository at the Hospital for Special Surgery
Condition: Scleroderma
Intervention:
29 Active, not recruiting Scleroderma Treatment With Celution Processed Adipose Derived Regenerative Cells (STAR)
Conditions: Scleroderma;   Systemic Sclerosis;   Raynaud Phenomena;   Raynaud's Disease
Interventions: Device: Celution Device;   Other: Placebo
30 Not yet recruiting Oral Manifestations of Systemic Sclerosis
Condition: Scleroderma, Systemic
Intervention: Radiation: Cone Beam Computed Tomography (CBCT)
31 Completed Light Treatment for Scleroderma Finger Ulcers
Conditions: Scleroderma, Systemic;   Ulcer
Intervention: Device: Custom-built phototherapy lamp
32 Completed Scleroderma: Cyclophosphamide or Transplantation (SCOT)
Conditions: Scleroderma, Systemic;   Sclerosis;   Autoimmune Disease
Interventions: Procedure: Autologous stem cell transplantation;   Drug: Cyclophosphamide;   Drug: Antithymocyte globulin, equine;   Drug: Methylprednisolone;   Drug: Growth colony stimulating factor (G-CSF);   Radiation: Total body irradiation (TBI)
33 Recruiting Role of Circulating Cytotoxic Lymphocytes in Endothelial Cell Injury in Systemic Sclerosis
Condition: Scleroderma, Systemic
Intervention: Other: blood samples
34 Recruiting Zibotentan Better Renal Scleroderma Outcome Study
Conditions: Scleroderma;   Scleroderma Renal Crisis;   Chronic Kidney Disease
Intervention: Drug: Zibotentan
35 Recruiting Efficacy and Safety of Riociguat in Patients With Systemic Sclerosis
Condition: Scleroderma, Systemic
Interventions: Drug: Riociguat (Adempas, BAY63-2521);   Drug: Placebo
36 Completed Laser Speckle Contrast Imaging for Cutaneous Microvascular Dysfunction Detection in Systemic Sclerosis.
Conditions: Raynaud Disease;   Scleroderma, Systemic
Interventions: Procedure: laser speckle contrast imaging;   Procedure: Cooling
37 Active, not recruiting The Impact of Illness Perceptions on Health Related Outcomes in Patients With Lupus and Systemic Sclerosis
Conditions: Lupus Erythematosus, Systemic;   Scleroderma, Systemic
Intervention: Other: Questionnaires
38 Withdrawn Stress Echocardiography in the Detection of Pulmonary Arterial Hypertension in Systemic Sclerosis Patients
Conditions: Scleroderma, Systemic;   Hypertension, Pulmonary
Intervention:
39 Not yet recruiting The Clinical And Subclinical Effects on Arterial Stiffness of Bosentan in Patients With Systemic Sclerosis
Condition: Scleroderma, Systemic
Intervention: Drug: bosentan
40 Recruiting A Trial to Compare Nintedanib With Placebo for Patients With Scleroderma Related Lung Fibrosis
Condition: Scleroderma, Systemic
Interventions: Drug: Nintedanib;   Drug: Placebo

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Indicates status has not been verified in more than two years