Now Available: Final Rule for FDAAA 801 and NIH Policy on Clinical Trial Reporting
272 studies found for:    "Scleroderma, Systemic"
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Rank Status Study
1 Not yet recruiting Oral Ifetroban to Treat Diffuse Cutaneous Systemic Sclerosis (SSc) or SSc-associated Pulmonary Arterial Hypertension
Conditions: Scleroderma, Diffuse;   Scleroderma, Systemic;   Scleroderma, Limited;   Sclerosis, Progressive Systemic;   Skin Diseases;   Connective Tissue Diseases;   Pathologic Processes;   Autoimmune Diseases
Interventions: Drug: Oral Ifetroban;   Drug: Oral Placebo
2 Completed
Has Results
Scleroderma Lung Disease
Conditions: Lung Diseases;   Pulmonary Fibrosis;   Systemic Scleroderma;   Scleroderma, Systemic
Interventions: Drug: Cyclophosphamide;   Drug: Placebo
3 Completed Efficacy and Safety of Imatinib in Scleroderma
Conditions: Scleroderma, Localized;   Scleroderma, Systemic
Intervention: Drug: imatinib mesylate
4 Unknown  Effect of Sildenafil on the Microcirculatory Blood Flow and Endothelial Progenitor Cells in Systemic Sclerosis
Conditions: Scleroderma, Systemic;   Scleroderma, Diffuse;   Scleroderma, Limited;   Raynaud Phenomenon
Interventions: Drug: Sildenafil citrate;   Drug: Placebo
5 Active, not recruiting Study of Pomalidomide (CC-4047) to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Effectiveness for Subjects With Systemic Sclerosis With Interstitial Lung Disease
Conditions: Scleroderma, Systemic;   Sclerosis, Systemic;   Systemic Scleroderma;   Systemic Sclerosis
Interventions: Drug: Pomalidomide (CC-4047);   Drug: Placebo
6 Completed
Has Results
A Study to Evaluate the Safety and Efficacy of Abatacept in Patients With Diffuse Systemic Sclerosis (Scleroderma)
Conditions: Scleroderma, Diffuse;   Scleroderma, Systemic
Intervention: Drug: Abatacept
7 Completed
Has Results
Digital Ischemic Lesions in Scleroderma Treated With Oral Treprostinil Diethanolamine
Conditions: Systemic Sclerosis;   Scleroderma
Interventions: Drug: treprostinil diethanolamine;   Drug: placebo
8 Completed
Has Results
Pulmonary Involvement in Scleroderma: A Clinical Study of the Safety and Efficacy of Mycophenolate Mofetil in Scleroderma Patients With Lung Involvement
Condition: Scleroderma, Systemic
Intervention: Drug: Mycophenolate mofetil
9 Completed Psychological Treatments for Scleroderma
Conditions: Pain;   Depression;   Scleroderma;   Systemic Sclerosis
Interventions: Behavioral: Cognitive behavioral therapy;   Behavioral: Disease/health education;   Behavioral: Self-help cognitive behavioral intervention facilitated by a psychologist
10 Completed Efficacy and Safety Study of GB-0998 for Treatment of Systemic Sclerosis
Condition: Scleroderma, Systemic
Intervention: Drug: High-dose intravenous immunoglobulin (Venoglobulin-IH)
11 Recruiting Gastroesophageal Reflux Treatment in Scleroderma
Conditions: Gastroesophageal Reflux Disease;   Systemic Sclerosis;   Scleroderma
Interventions: Drug: Alginic acid;   Drug: placebo (for domperidone);   Drug: Domperidone;   Drug: placebo (of alginic acid)
12 Terminated Thalidomide for Decreasing Collagen Biosynthesis in People With Progressive Systemic Sclerosis
Condition: Scleroderma, Systemic
Interventions: Drug: Thalidomide;   Drug: Placebo thalidomide
13 Recruiting Obstructive Sleep Apnea in Scleroderma and Pulmonary Involvement
Conditions: Scleroderma, Systemic;   Sleep Apnea, Obstructive;   Pulmonary Disease
Intervention: Other: No intervention
14 Completed Multi-center, Web Based Observational Study of Pulmonary Hypertension in Scleroderma Patients
Conditions: Systemic Sclerosis;   Scleroderma;   Pulmonary Hypertension;   Pulmonary Arterial Hypertension
15 Terminated Safety and Value of Self Bone Marrow Transplants Following Chemotherapy in Scleroderma Patients
Conditions: Scleroderma;   Systemic Sclerosis
Interventions: Drug: Fludarabine;   Drug: Cyclophosphamide;   Drug: Thymoglobulin;   Procedure: Leukapheresis;   Procedure: Self bone marrow transplant
16 Completed A Non-Interventional Pilot Study Assessing Whether Lysyl Oxidase-like 2 (LOXL2) is Present in Subjects With Scleroderma
Conditions: Limited Scleroderma;   Diffuse Scleroderma
17 Completed Efficacy and Safety of Oral Bosentan in Pulmonary Fibrosis Associated With Scleroderma
Conditions: Pulmonary Fibrosis;   Scleroderma, Systemic
Intervention: Drug: Bosentan
18 Recruiting IVIG Treatment in Systemic Sclerosis
Conditions: Systemic Sclerosis;   Diffuse Scleroderma
Intervention: Biological: Privigen
19 Recruiting Proof-of-concept Trial of IVA337 in Diffuse Cutaneous Systemic Sclerosis
Conditions: Scleroderma, Diffuse;   Diffuse Cutaneous Systemic Sclerosis
Interventions: Drug: IVA337;   Drug: Placebo
20 Recruiting Cyclophosphamide Systemic Sclerosis Associated Interstitial Lung Disease
Conditions: Systemic Sclerosis;   Scleroderma;   Interstitial Lung Disease;   Lung Fibrosis
Interventions: Drug: Cyclophosphamide;   Drug: Placebo

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Indicates status has not been verified in more than two years