42 studies found for:    "Pure autonomic failure"
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1 Recruiting Local Heat Stress in Autonomic Failure Patients With Supine Hypertension
Conditions: Hypertension;   Pure Autonomic Failure;   Multiple System Atrophy;   Autonomic Failure
Interventions: Other: Passive heat stress;   Other: Control (non-heating)
2 Recruiting Hemodynamic Mechanisms of Abdominal Compression in the Treatment of Orthostatic Hypotension in Autonomic Failure
Conditions: Orthostatic Hypotension;   Pure Autonomic Failure;   Multiple System Atrophy;   Autonomic Failure
Interventions: Other: Abdominal compression;   Other: Sham abdominal compression;   Drug: Placebo pill;   Drug: midodrine
3 Completed Autonomic Failure Patients for RNA Blood Sampling
Conditions: Pure Autonomic Failure;   Multiple System Atrophy;   Parkinson's Plus Syndromes
Intervention:
4 Recruiting Magnetic Resonance Spectroscopy in Autonomic Failure
Conditions: Pure Autonomic Failure;   Multiple System Atrophy
Intervention: Procedure: Magnetic Resonance Spectroscopy Imaging
5 Recruiting The Role of Endothelin in the Supine Hypertension of Autonomic Failure
Conditions: Hypertension;   Pure Autonomic Failure;   Multiple System Atrophy
Interventions: Drug: BQ123;   Drug: Bq123;   Drug: Saline
6 Recruiting Contribution of Angiotensin II to Supine Hypertension in Autonomic Failure
Conditions: Hypertension;   Pure Autonomic Failure;   Multiple System Atrophy
Interventions: Drug: Losartan;   Drug: Captopril;   Drug: Placebo
7 Recruiting Blood Pressure Lowering Effects of Angiotensin-(1-7) in Primary Autonomic Failure
Conditions: Autonomic Nervous System Disorders;   Pure Autonomic Failure;   Shy-Drager Syndrome;   Orthostatic Hypotension, Dysautonomic
Interventions: Drug: Angiotensin-(1-7);   Drug: Saline
8 Completed
Has Results
Nebivolol in the Supine Hypertension of Autonomic Failure
Conditions: Hypertension;   Pure Autonomic Failure;   Multiple System Atrophy
Interventions: Drug: Placebo;   Drug: Nebivolol 5 mg;   Drug: metoprolol tartrate 50 mg;   Drug: Sildenafil25 mg
9 Completed Plasma Exchange for Autoimmune Autonomic Failure
Conditions: Plasma Exchange;   Autonomic Failure
Intervention:
10 Recruiting Treatment of Orthostatic Hypotension in Autonomic Failure
Conditions: Autonomic Failure;   Orthostatic Hypotension
Interventions: Drug: Atomoxetine;   Drug: Acarbose;   Drug: Pyridostigmine Bromide;   Drug: Yohimbine;   Drug: Midodrine HCl;   Drug: placebo;   Drug: Modafinil;   Drug: Octreotide;   Other: water intake;   Drug: Diphenhydramine Hydrochloride;   Drug: Ranitidine HCL;   Drug: Tranylcypromine;   Drug: Ergotamine/ Caffeine;   Drug: Celecoxib;   Drug: Pseudoephedrine;   Drug: Methylphenidate;   Drug: Indomethacin;   Drug: Ibuprofen;   Drug: Oxymetazoline 0.05% nasal solution;   Dietary Supplement: Bovril;   Drug: Acetazolamide;   Drug: Rivastigmine tartrate;   Drug: Carbidopa/levodopa;   Device: Inflatable abdominal binder;   Device: inflatable abdominal binder (sham)
11 Completed Mechanisms Responsible for Hypoglycemia Associated Autonomic Failure
Conditions: Diabetes Mellitus;   Hypoglycemia;   Autonomic Failure
Interventions: Drug: naloxone;   Dietary Supplement: fructose;   Behavioral: exercise
12 Recruiting Hypoglycemia Associated Autonomic Failure in Type 1 Diabetes Mellitus (DM)
Conditions: Type 1 Diabetes;   Hypoglycemia Associated Autonomic Failure
Interventions: Drug: Fluoxetine;   Drug: Placebo control
13 Active, not recruiting Norepinephrine Transporter Blockade as a Pathological Biomarker in Neurogenic Orthostatic Hypotension
Conditions: Orthostatic Hypotension;   Pure Autonomic Failure;   Multiple System Atrophy;   Parkinson's Disease
Intervention:
14 Completed
Has Results
A Clinical Study for Patients With Neurogenic Orthostatic Hypotension (NOH) Using Droxidopa
Conditions: Symptomatic Neurogenic Orthostatic Hypotension (NOH);   Non-diabetic Neuropathy;   Primary Autonomic Failure;   Dopamine Beta Hydroxylase Deficiency
Interventions: Drug: Placebo;   Drug: Droxidopa
15 Completed
Has Results
Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH)
Conditions: Symptomatic Neurogenic Orthostatic Hypotension (NOH);   Non-diabetic Neuropathy;   Primary Autonomic Failure;   Dopamine Beta Hydroxylase Deficiency
Interventions: Drug: Placebo;   Drug: Droxidopa
16 Active, not recruiting The Autonomic Nervous System and Obesity
Conditions: OBESITY;   HYPERTENSION;   PURE AUTONOMIC FAILURE;   SHY-DRAGER SYNDROME
Interventions: Drug: Trimethaphan;   Drug: Pseudoephedrine
17 Recruiting Retinal Abnormalities as Biomarker of Disease Progression and Early Diagnosis of Parkinson Disease
Conditions: Parkinson Disease;   Multiple System Atrophy;   REM Sleep Behavior Disorder;   Pure Autonomic Failure;   Dementia With Lewy Bodies
Intervention:
18 Terminated
Has Results
A Clinical Study of Patients With Symptomatic NOH to Assess Sustained Effects of Droxidopa Therapy
Conditions: Symptomatic Neurogenic Orthostatic Hypotension;   Parkinson's Disease;   Multiple Systems Atrophy;   Pure Autonomic Failure;   Dopamine Beta Hydroxylase Deficiency
Interventions: Drug: Droxidopa;   Drug: Placebo
19 Recruiting Biomarkers of Risk of Parkinson Disease
Conditions: Parkinson Disease;   Autonomic Nervous System Diseases;   Pure Autonomic Failure
Intervention:
20 Completed
Has Results
Nitric Oxide and the Autonomic Nervous System
Conditions: Hypertension;   Pure Autonomic Failure
Interventions: Drug: L-NMMA;   Drug: Trimethaphan

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