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344 studies found for:    "Pulmonary Emphysema"
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1 Recruiting Clinical Study of the Efficacy and Safety of the Application of Allogeneic Mesenchymal (Stromal) Cells of Bone Marrow, Cultured Under the Hypoxia in the Treatment of Patients With Severe Pulmonary Emphysema
Condition: Pulmonary Emphysema
Interventions: Biological: Mesenchymal stem cells;   Other: Reference therapy: 400 mL of 0.9% NaCl solution
2 Completed Low Cost Biological Lung Volume Reduction Therapy for Advanced Emphysema
Condition: Pulmonary Emphysema
Intervention: Procedure: Bronchoscopic Lung volume reduction
3 Completed Safety Study of Bone-marrow Derived Mesenchymal Stromal Cells Associated With Endobronchial Valves in Emphysema
Condition: Pulmonary Emphysema
Intervention: Procedure: Bronchoscopy
4 Not yet recruiting Clinical Study to Evaluate the Exercise Capacity in Patients With Severe Emphysema Treated With Coils
Condition: Pulmonary Emphysema
Interventions: Procedure: 10 coils in upper lobes;   Procedure: 15 coils in upper and lower lobes;   Procedure: cycloergometry
5 Terminated Netherlands 10 mL Bronchoscopic Lung Volume Reduction (BLVR) Phase 1/2 Emphysema Study - Initial Formulation
Condition: Pulmonary Emphysema
Intervention: Biological: BLVR Hydrogel
6 Unknown  The Effect and Mechanism of Bronchoscopic Lung Volume Reduction by Endobronchial Valve in Korean Emphysema Patients
Condition: Pulmonary Emphysema
Intervention: Device: Endobronchial valve
7 Recruiting Efficacy and Safety of Alpha1-Proteinase Inhibitor (Human), Modified Process (Alpha-1 MP) in Subjects With Pulmonary Emphysema Due to Alpha1 Antitrypsin Deficiency (AATD)
Condition: Pulmonary Emphysema in Alpha-1 PI Deficiency
Interventions: Biological: Alpha1-proteinase inhibitor (human), modified process (Alpha-1 MP);   Other: 0.9% Sodium Chloride for Injection, USP
8 Terminated Israeli 10 mL Bronchoscopic Lung Volume Reduction (BLVR) Phase 1/2 Emphysema Study - Initial Formulation
Condition: Pulmonary Emphysema
Intervention: Biological: BLVR Hydrogel
9 Active, not recruiting Long Term Follow up Investigation of Endobronchial Valves in Emphysema
Condition: Pulmonary Emphysema
Intervention: Device: Zephyr Endobronchial Valve (EBV)
10 Terminated Study of the AeriSeal System for HyPerInflation Reduction in Emphysema (ASPIRE)
Condition: Pulmonary Emphysema
Interventions: Device: Treatment plus Optimal Medical Therapy;   Other: Optimal Medical Therapy
11 Completed US 10 mL Bronchoscopic Lung Volume Reduction (BLVR) Phase 1 Emphysema Study - Initial Formulation
Condition: Pulmonary Emphysema
Intervention: Biological: BLVR
12 Completed US 10 mL Biologic Lung Volume Reduction (BLVR) Phase 2 Emphysema Study
Condition: Pulmonary Emphysema
Intervention: Biological: BLVR Treatment
13 Completed US 10 mL Biologic Lung Volume Reduction (BLVR) Phase 1 Emphysema Study
Condition: Pulmonary Emphysema
Intervention: Drug: BLVR System
14 Terminated Collateral Ventilation Effects on Response to AeriSeal System Treatment in Upper Lobe Predominant Emphysema
Condition: Pulmonary Emphysema
Intervention: Device: Emphysematous Lung Sealant
15 Unknown  Implantation of Endobronchial Valves Versus Intrabronchial Valves in Patients With Severe Heterogeneous Emphysema
Condition: Pulmonary Emphysema
Interventions: Device: EBV implantation;   Device: IBV implantation
16 Completed Safety and Feasibility Study of Administration of Mesenchymal Stemcells for Treatment of Emphysema
Condition: Emphysema
Intervention: Biological: autologous bone marrow derived mesenchymal stromal cells
17 Completed Prevalence of Alpha-1 Antitrypsin Dysfunction in Pulmonary Emphysema
Condition: Pulmonary Emphysema
Intervention: Other: Blood sampling
18 Unknown  Safety Study of Endobronchial Transplantation of Autologous Mesenchymal Stem Cells (MSCs) in Emphysema Patients
Condition: Emphysema
Intervention: Biological: Autologous MSCs transplantation
19 Completed Randomized Comparison of the RePneu Lung Volume Reduction Coil (LVRC) to Standard of Care for the Treatment of Emphysema (RESET Study)
Condition: Emphysema
Interventions: Device: Lung Volume Reduction Coil (LVRC) (PneumRx);   Device: Control
20 Not yet recruiting Losartan Effects on Emphysema Progression
Condition: Emphysema
Interventions: Drug: Losartan;   Drug: Placebo

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Study has passed its completion date and status has not been verified in more than two years.