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37 studies found for:    "Porphyria"
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"Porphyria" (37 records)
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Rank Status Study
1 Recruiting Controlled Trial of Panhematin in Treatment of Acute Attacks of Porphyria
Condition: Acute Porphyrias
Interventions: Biological: Panhematin;   Other: Placebo
2 Completed Observational Study of Acute Intermittent Porphyria Patients
Condition: Acute Intermittent Porphyria
Intervention:
3 Recruiting A Phase 1 Study of ALN-AS1 in Patients With Acute Intermittent Porphyria (AIP)
Condition: Acute Intermittent Porphyria
Interventions: Drug: ALN-AS1;   Drug: Sterile Normal Saline (0.9% NaCl)
4 Recruiting Longitudinal Study of the Porphyrias
Conditions: Acute Porphyrias;   Cutaneous Porphyrias
Intervention:
5 Recruiting Hydroxychloroquine and Phlebotomy for Treating Porphyria Cutanea Tarda
Condition: Porphyria Cutanea Tarda
Interventions: Drug: Hydroxychloroquine;   Procedure: Phlebotomy
6 Completed Phase I Gene Therapy Clinical Trial Using the Vector rAAV2/5-PBGD for the Treatment of Acute Intermittent Porphyria
Condition: Acute Intermittent Porphyria
Interventions: Genetic: rAAV2/5-PBGD vector dosage 1;   Genetic: rAAV2/5-PBGD vector dosage 2;   Genetic: rAAV2/5-PBGD vector dosage 3;   Genetic: rAAV2/5-PBGD vector dosage 4
7 Enrolling by invitation A Study to Evaluate Long-term Safety and Clinical Activity of ALN-AS1 in Patient With Acute Intermittent Porphyria (AIP)
Condition: Acute Intermittent Porphyria
Intervention: Drug: ALN-AS1
8 Completed Risk Factors of Porphyria Cutanea Tarda (PCT)
Condition: Porphyria Cutanea Tarda
Intervention:
9 Completed
Has Results
Pilot Trial of Deferasirox in the Treatment of Porphyria Cutanea Tarda
Condition: Porphyria Cutanea Tarda
Intervention: Drug: Deferasirox
10 Not yet recruiting Dental Health, Diet, Inflammation and Biomarkers in Patients With Acute Intermittent Porphyria(AIP)
Condition: Acute Intermittent Porphyria
Intervention:
11 Unknown  Studies in Porphyria I: Characterization of Enzyme Defects
Condition: Porphyria
Intervention:
12 Completed Study of Nutritional Factors in Porphyria
Condition: Porphyria
Intervention:
13 Completed Studies in Porphyria III: Heme and Tin Mesoporphyrin in Acute Porphyrias
Condition: Porphyria
Interventions: Drug: heme arginate;   Drug: tin mesoporphyrin
14 Completed Studies in Porphyria IV: Gonadotropin-Releasing Hormone (GnRH) Analogues for Prevention of Cyclic Attacks
Condition: Porphyria
Intervention: Drug: luteinizing hormone-releasing factor
15 Completed Phase I/II Study of Heme Arginate and Tin Mesoporphyrin for Acute Porphyria
Condition: Porphyria
Interventions: Drug: heme arginate;   Drug: tin mesoporphyrin
16 Completed Phase I Study of Heme Arginate With or Without Tin Mesoporphyrin in Patients With Acute Attacks of Porphyria
Condition: Porphyria
Interventions: Drug: heme arginate;   Drug: tin mesoporphyrin
17 Completed Phase I Study of Tin Mesoporphyrin in Patients on Long Term Heme Therapy for Prevention of Acute Attacks of Porphyria
Condition: Porphyria
Interventions: Drug: heme arginate;   Drug: tin mesoporphyrin
18 Active, not recruiting EXPLORE: A Natural History Study of Acute Hepatic Porphyria (AHP)
Condition: Acute Hepatic Porphyria
Intervention:
19 Enrolling by invitation Acute Porphyria Biomarkers
Conditions: Acute Intermittent Porphyria;   Hereditary Coproporphyria;   Variegate Porphyria
Intervention: Drug: Hemin
20 Unknown  Safety and Efficacy of Oral Deferasirox in Patients With Porphyria Cutanea Tarda
Condition: Porphyria Cutanea Tarda
Intervention: Drug: Exjade

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Study has passed its completion date and status has not been verified in more than two years.