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77 studies found for:    "Optic neuritis"
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Rank Status Study
21 Completed
Has Results
A Randomized, Double-blind, Placebo-controlled, Multicenter Study of the Effects of Glatiramer Acetate (GA) on the Retinal Nerve Fiber Layer (RNFL) and Visual Function in Patients With a First Episode of Acute Optic Neuritis (AON). (Octagon)
Condition: Optic Neuritis
Interventions: Drug: Glatiramer Acetate;   Drug: placebo
22 Unknown  Optic Neuritis Treatment Trial (ONTT)
Conditions: Multiple Sclerosis;   Optic Neuritis
Interventions: Drug: Methylprednisolone;   Drug: Prednisone
23 Unknown  Longitudinal Optic Neuritis Study (LONS)
Conditions: Multiple Sclerosis;   Optic Neuritis
Interventions: Drug: Methylprednisolone;   Drug: Prednisone
24 Completed Intravenous Immunoglobulin Therapy in Optic Neuritis
Condition: Optic Neuritis
Intervention: Drug: Immunoglobulin
25 Recruiting A Longitudinal Study of Neuromyelitis Optica and Transverse Myelitis
Conditions: Neuromyelitis Optica;   Neuromyelitis Optica Spectrum Disorder;   Transverse Myelitis;   Optic Neuritis
26 Recruiting Manganese-Enhanced Magnetic Resonance Imaging in Healthy Volunteers and People With Multiple Sclerosis
Conditions: Multiple Sclerosis;   Optic Neuritis
Intervention: Drug: Mangafodipir (Teslascan)
27 Active, not recruiting Biobank For MS And Other Demyelinating Diseases
Conditions: Multiple Sclerosis;   Transverse Myelitis;   Neuromyelitis Optica;   Acute Disseminated Encephalomyelitis;   Optic Neuritis
28 Completed Long Term Study of Avonex Therapy Following a First Attack of Multiple Sclerosis
Conditions: Multiple Sclerosis;   Optic Neuritis;   Transverse Myelitis;   Acute Brainstem/Cerebellar Syndrome
Intervention: Drug: interferon beta 1a 30 ug IM once weekly
29 Withdrawn Induction Therapy With a Single High Dose Bolus of Intravenous Methotrexate With Leucovorin Rescue, Prior to Initiation of AVONEX® Treatment, in Patients Presenting With a First Acute Demyelinating Event.
Conditions: Demyelinating Disorders;   Multiple Sclerosis;   Optic Neuritis;   Myelitis;   Neuritis
Interventions: Drug: interferon beta 1a;   Drug: methotrexate;   Drug: methylprednisolone
30 Suspended Natural History of Optic Neuritis
Condition: Multiple Sclerosis
31 Unknown  A Phase IV Trial of Neuroprotection With ACTH in Acute Optic Neuritis
Condition: Multiple Sclerosis
Interventions: Drug: ACTHAR Gel (ACTH);   Drug: IV steroids with oral taper
32 Active, not recruiting Effect of MD1003 in Chronic Visual Loss Related to Optic Neuritis in Multiple Sclerosis
Condition: Multiple Sclerosis
Intervention: Drug: MD1003 100mg capsule
33 Recruiting Pupillometry Dynamic Measures in Patients Without Ocular or Neurological Disease
Condition: Optic Neuritis
Intervention: Device: pupillary light reflex
34 Recruiting The Correlation Between AQP-4 Ab and the Visual Function of Patients With Demyelinating ON at Onset
Condition: Optic Neuritis
Intervention: Biological: blood test of anti-AQP4 antibody
35 Completed Optical Coherence Tomography in Multiple Sclerosis Patients
Conditions: Multiple Sclerosis;   Optic Neuritis
36 Active, not recruiting Pharmacokinetics, Safety and Tolerability of Single Doses of BIIB033 (Opicinumab) Produced by 2 Manufacturing Processes
Conditions: Multiple Sclerosis;   Acute Optic Neuritis
Intervention: Drug: BIIB033 (opicinumab)
37 Enrolling by invitation Long-Term Assessment of Remyelinating Therapy
Condition: Acute Optic Neuritis
38 Enrolling by invitation Optical Coherence Tomography and Optic Neuritis (OCTON)
Condition: Optical Neuritis
39 Recruiting MOdification of VIsual Outcomes After Optic Neuritis in CIS or MS by Gilenya (MOVING Study)
Condition: Multiple Sclerosis
Interventions: Drug: Verum arm receiving Gilenya®;   Drug: Active Comparator receiving Extavia®
40 Recruiting Ublituximab for Acute Neuromyelitis Optica (NMO) Relapses
Conditions: Neuromyelitis Optica;   Neuromyelitis Optica Spectrum Disorder
Intervention: Drug: Ublituximab

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Indicates status has not been verified in more than two years