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27 studies found for:    "Nevoid basal cell carcinoma syndrome"
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Rank Status Study
1 Completed
Has Results
Efficacy, Safety and Pharmacokinetics of Oral LDE225 in Treatment of Patients With Nevoid Basal Cell Carcinoma Syndrome (NBCCS)
Conditions: Basal Cell Carcinoma;   Gorlin Syndrome;   Nevoid Basal Cell Carcinoma Syndrome
Interventions: Drug: LDE225;   Drug: Placebo
2 Active, not recruiting Blue vs Red Light During Levulan Based Photodynamic Therapy in Patients With Basal Cell Nevus Syndrome
Condition: Basal Cell Nevus Syndrome
Interventions: Drug: Levulan;   Other: Red Light Photodynamic Therapy;   Other: Blue Light Photodynamic Therapy
3 Terminated Two Studies to Determine if Verteporfin PDT is Effective & Safe in Treating Multiple Basal Cell Carcinoma of the Skin.
Conditions: Basal Cell Carcinoma;   Nevoid Basal Cell Carcinoma Syndrome;   Gorlin Syndrome
Intervention: Drug: verteporfin PDT
4 Completed Trial of Patidegib Gel 2%, 4%, and Vehicle to Decrease the Number of Surgically Eligible Basal Cell Carcinomas (BCC) in Gorlin Syndrome Patients
Condition: Basal Cell Nevus Syndrome
Interventions: Drug: patidegib;   Drug: vehicle gel
5 Active, not recruiting Photodynamic Therapy Using Blue Light or Red Light in Treating Basal Cell Carcinoma in Patients With Basal Cell Nevus Syndrome
Conditions: Basal Cell Carcinoma of the Skin;   Nevoid Basal Cell Carcinoma Syndrome
Interventions: Drug: aminolevulinic acid hydrochloride;   Drug: photodynamic therapy;   Other: laboratory biomarker analysis;   Other: questionnaire administration
6 Active, not recruiting Study of BMS-833923 in Two Specific Patients With Basal Cell Nevus Syndrome
Condition: Basal Cell Nevus Syndrome
Intervention: Drug: BMS-833923
7 Completed To Determine The Efficacy and Safety of GDC-0449 in Patients With Basal Cell Nevus Syndrome (BCNS)
Conditions: Basal Cell Nevus Syndrome;   Gorlin Syndrome
Intervention: Drug: GDC-0449
8 Completed Trial Comparing the Effects of Intermittent Vismodegib vs. PDT in Patients With Multiple Basal Cell Carcinomas
Conditions: Basal Cell Nevus Syndrome;   Gorlin's Syndrome
Interventions: Drug: Vismodegib;   Drug: Aminolevulinic acid %20 topical solution
9 Completed
Has Results
A Trial to Evaluate the Safety, Local Tolerability, Pharmacokinetics and Pharmacodynamics of LDE225 on Skin Basal Cell Carcinomas in Gorlin Syndrome Patients
Condition: Treatment for Basal Cell Carcinomas (BCCs) in Gorlin Syndrome Patients
Interventions: Drug: Vehicle;   Drug: LDE225 0.25%;   Drug: LDE225 0.75%
10 Completed
Has Results
Topical Tazarotene in Treating Patients With Basal Cell Skin Cancer and Basal Cell Nevus Syndrome on the Chest and Back
Condition: Skin Carcinoma
Interventions: Drug: tazarotene;   Other: placebo
11 Withdrawn Efficacy, Safety and Tolerability of Topically Applied LDE225 Cream (Hedgehog Pathway Inhibitor) in Adult Patients With Nevoid Basal Cell Carcinoma Syndrome (NBCCS)
Condition: Basal Cell Carcinoma
Interventions: Drug: LDE225B;   Drug: Vehicle
12 Completed
Has Results
Topical Tazarotene in Treating Patients With Basal Cell Skin Cancer and Basal Cell Nevus Syndrome on the Face
Condition: Neoplastic Syndrome
Intervention: Drug: tazarotene
13 Completed Topical Sirolimus in Patients With Basal Cell Nevus Syndrome and in Healthy Participants
Conditions: Neoplastic Syndrome;   Non-melanomatous Skin Cancer
Interventions: Drug: sirolimus;   Genetic: comparative genomic hybridization;   Genetic: gene expression analysis;   Genetic: microarray analysis;   Genetic: protein expression analysis;   Genetic: proteomic profiling;   Other: laboratory biomarker analysis;   Other: mass spectrometry;   Procedure: biopsy
14 Completed Celecoxib in Preventing Basal Cell Carcinoma in Patients With Basal Cell Nevus Syndrome
Condition: Non-melanomatous Skin Cancer
Intervention: Drug: celecoxib
15 Completed Use of an SPF30 Sunscreen and an After-sun-lotion in Skin Cancer Risk Patients
Conditions: Skin Cancer;   Xeroderma Pigmentosum;   Basal Cell Nevus Syndrome
Intervention:
16 Recruiting Photodynamic Therapy and Vismodegib for Multiple Basal Cell Carcinomas
Condition: Basal Cell Carcinoma
Intervention: Drug: Vismodegib
17 Active, not recruiting
Has Results
A Study of Two Vismodegib Regimens in Participants With Multiple Basal Cell Carcinomas
Condition: Basal Cell Carcinoma
Interventions: Drug: Vismodegib;   Drug: Placebo
18 Recruiting Open-label Trial of SUBA™-Itraconazole (SUBA-Cap) in Subjects With Basal Cell Carcinoma Nevus Syndrome (BCCNS)
Condition: Basal Cell Carcinoma in Basal Cell Nevus Syndrome
Intervention: Drug: SUBA-Itraconazole
19 Completed The Evaluation of Oral Acitretin in the Treatment of Psoriasis, Cutaneous Disorders of Keratinization, Multiple Basal Cell Carcinomas and Other Retinoid Responsive Diseases
Conditions: Basal Cell Carcinoma;   Keratosis Palmaris et Plantaris;   Psoriasis
Intervention:
20 Active, not recruiting Sonidegib and Buparlisib in Treating Patients With Advanced or Metastatic Basal Cell Carcinoma
Conditions: Basal Cell Carcinoma of the Skin;   Nevoid Basal Cell Carcinoma Syndrome;   Recurrent Skin Cancer
Interventions: Drug: Buparlisib;   Drug: Sonidegib

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Study has passed its completion date and status has not been verified in more than two years.