70 studies found for:    "Multiple Sclerosis, Chronic Progressive"
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21 Recruiting A Phase 2 Clinical Study in Subjects With Primary Progressive Multiple Sclerosis to Assess the Efficacy, Safety and Tolerability of Two Oral Doses of Laquinimod Either of 0.6 mg/Day or 1.5mg/Day (Experimental Drug) as Compared to Placebo
Condition: Primary Progressive Multiple Sclerosis
Interventions: Drug: Laquinimod;   Drug: Placebo
22 Recruiting Efficacy, Safety and Tolerability of Andrographolides Versus Placebo in Patients With Progressive Forms of MS
Conditions: Primary Progressive Multiple Sclerosis;   Multiple Sclerosis, Secondary Progressive
Interventions: Drug: Andrographolides;   Drug: placebo
23 Recruiting Improving Cognitive Aptitudes With tDCS in Patients With Multiple Sclerosis
Conditions: Relapsing Remitting Multiple Sclerosis;   Secondary-progressive Multiple Sclerosis;   Cognitive Deficits;   Motor Deficits
Intervention: Device: tDCS
24 Recruiting A Phase 1 Trial of Intrathecal Rituximab for Progressive Multiple Sclerosis Patients
Conditions: Primary Progressive Multiple Sclerosis;   Secondary Progressive Multiple Sclerosis
Intervention: Drug: Rituximab
25 Active, not recruiting Safety and Efficacy Study of MIS416 to Treat Secondary Progressive Multiple Sclerosis
Condition: Secondary Progressive Multiple Sclerosis
Interventions: Biological: MIS416;   Drug: Saline
26 Recruiting A Double Blind, Randomized, Placebo Controlled, Crossover Study of the Effectiveness of Oral Fampridine in Improving Upper Limb Function in Progressive Multiple Sclerosis
Conditions: Secondary Progressive Multiple Sclerosis;   Primary Progressive Multiple Sclerosis
Interventions: Drug: Fampridine;   Drug: Placebo
27 Recruiting Measuring Active Microglia in Progressive Multiple Sclerosis
Condition: Secondary Progressive Multiple Sclerosis
Intervention: Radiation: [C11]PK-1195 PET scan
28 Active, not recruiting Tear Analysis in the Diagnosis of Multiple Sclerosis
Condition: Primary Progressive Multiple Sclerosis
Intervention: Procedure: tears sampling
29 Active, not recruiting Safety, Tolerability and Activity Study of Ibudilast in Subjects With Progressive Multiple Sclerosis
Conditions: Multiple Sclerosis, Primary Progressive;   Multiple Sclerosis, Secondary Progressive
Interventions: Drug: ibudilast;   Drug: Placebo
30 Recruiting ACTH in Progressive Forms of MS
Conditions: Secondary Progressive Multiple Sclerosis;   Primary Progressive Multiple Sclerosis;   Progressive Relapsing Multiple Sclerosis
Interventions: Drug: ACTH;   Drug: Placebo
31 Active, not recruiting A Safety and Efficacy Study of Oral Prolonged-Release Fampridine (BIIB041) in Japanese Participants With Multiple Sclerosis
Conditions: Multiple Sclerosis, Remittent Progressive;   Multiple Sclerosis, Primary Progressive;   Relapsing-Remitting Multiple Sclerosis;   Secondary Progressive Multiple Sclerosis;   Multiple Sclerosis
Interventions: Drug: Placebo;   Drug: BIIB041 (fampridine)
32 Recruiting MS-SMART: Multiple Sclerosis-Secondary Progressive Multi-Arm Randomisation Trial
Condition: Secondary Progressive Multiple Sclerosis
Interventions: Drug: Amiloride;   Drug: Riluzole;   Drug: Fluoxetine;   Drug: Placebo
33 Recruiting A Trial to Compare the Effectiveness of Two Rehabilitation Programs for Multiple Sclerosis Patients
Conditions: Primary Progressive Multiple Sclerosis,;   Secondary Progressive Multiple Sclerosis;   Relapsing-remitting Multiple Sclerosis,;   Demyelinating Autoimmune Diseases,;   Nervous System Diseases
Interventions: Behavioral: Combined program;   Behavioral: Physiotherapy in private practice
34 Enrolling by invitation Idebenone for Primary Progressive Multiple Sclerosis
Conditions: Multiple Sclerosis;   Primary Progressive Multiple Sclerosis
Intervention: Drug: Idebenone
35 Completed OL, Single-arm Extension Study to the Double-blind, Randomized, Multicenter, Placebo-controlled, Parallel-group Study Comparing the Efficacy and Safety of 0.5 mg FTY720 Administered Orally Once Daily Versus Placebo in Patients With Primary Progressive Multiple Sclerosis
Condition: Primary Progressive Multiple Sclerosis
Intervention: Drug: FTY720
36 Recruiting Serial Collection of Primary Progressive Multiple Sclerosis Participants in the MURDOCK Study
Condition: Primary Progressive Multiple Sclerosis
Intervention: Other: generation of 'omic markers of disease progression
37 Recruiting A Pilot Study to Assess microRNA Biomarkers in Early and Later Stage Multiple Sclerosis
Conditions: Multiple Sclerosis;   Secondary Progressive Multiple Sclerosis;   Clinically Isolated Syndrome
Intervention:
38 Active, not recruiting Study of Tcelna (Imilecleucel-T) in Secondary Progressive Multiple Sclerosis
Conditions: Autoimmune Diseases of the Nervous System;   Multiple Sclerosis;   Secondary Progressive Multiple Sclerosis;   Disease Progression;   Brain Atrophy
Interventions: Biological: Tcelna;   Biological: Placebo
39 Active, not recruiting Exploring the Efficacy and Safety of Siponimod in Patients With Secondary Progressive Multiple Sclerosis (EXPAND)
Condition: Secondary Progressive Multiple Sclerosis
Interventions: Drug: BAF312;   Drug: Placebo
40 Recruiting Functional Electrical Stimulation for Individuals With Secondary Progressive Multiple Sclerosis
Condition: Secondary Progressive Multiple Sclerosis
Interventions: Behavioral: Active cycling;   Behavioral: Passive cycling

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Indicates status has not been verified in more than two years