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225 studies found for:    "Medulloblastoma"
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Rank Status Study
1 Recruiting Study Assessing the Feasibility of a Surgery and Chemotherapy-Only in Children With Wnt Positive Medulloblastoma
Condition: Medulloblastoma
Interventions: Drug: Lomustine;   Drug: Vincristine;   Drug: Cisplatin;   Drug: Cyclophosphamide;   Drug: Mesna
2 Recruiting A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed Medulloblastoma
Condition: Medulloblastoma
Interventions: Radiation: Craniospinal Irradiation with boost to the primary tumor site;   Drug: Cyclophosphamide;   Drug: Cisplatin;   Drug: Vincristine;   Drug: Vismodegib;   Drug: Pemetrexed;   Drug: Gemcitabine;   Other: Aerobic Training;   Other: Neurocognitive Remediation
3 Active, not recruiting Multicenter Pilot-study for the Therapy of Medulloblastoma of Adults
Condition: Medulloblastoma
Interventions: Drug: maintenance chemotherapy (vincristin, cisplatin and CCNU);   Radiation: Radiotherapy
4 Recruiting Metronomic and Targeted Anti-angiogenesis Therapy for Children With Recurrent/Progressive Medulloblastoma
Condition: Medulloblastoma
Interventions: Drug: Bevacizumab;   Drug: Thalidomide;   Drug: Celecoxib;   Drug: Fenofibric acid;   Drug: Etoposide;   Drug: Cyclophosphamide;   Drug: Etoposide phosphate;   Drug: Liposomal cytarabine
5 Active, not recruiting A Phase II Study of Oral LDE225 in Patients With Hedge-Hog (Hh)-Pathway Activated Relapsed Medulloblastoma (MB)
Condition: Medulloblastoma
Intervention: Drug: LDE225
6 Recruiting Social Cognition and Brain Integrity in Survivors of Pediatric Medulloblastoma
Condition: Medulloblastoma
Intervention:
7 Recruiting Radiation Therapy and Combination Chemotherapy for Medulloblastoma
Condition: Medulloblastoma
Interventions: Drug: Temozolomide;   Radiation: Craniospinal Radiation
8 Active, not recruiting Hyperfractionated Versus Conventionally Fractionated Radiotherapy in Standard Risk Medulloblastoma
Condition: Medulloblastoma
Interventions: Radiation: Standard Fractionation Regimen;   Radiation: Hyperfractionated Radiotherapy
9 Recruiting Interest of a Dose Decrease for Radiotherapy Associated With Chemotherapy for Treatment of Standard Risk Adult Medulloblastomas
Condition: Medulloblastoma
Interventions: Drug: carboplatine;   Drug: Etoposide;   Radiation: radiation therapy
10 Completed
Has Results
Vismodegib in Treating Patients With Recurrent or Refractory Medulloblastoma
Condition: Adult Medulloblastoma
Interventions: Other: Pharmacological Study;   Drug: Vismodegib
11 Recruiting Study of Sequential High-dose Chemotherapy in Children With High Risk Medulloblastoma
Condition: High-risk Medulloblastoma
Interventions: Drug: Carboplatin + etoposide;   Drug: Thiotepa;   Drug: Cyclophosphamide + Busilvex
12 Completed
Has Results
Vismodegib in Treating Younger Patients With Recurrent or Refractory Medulloblastoma
Condition: Recurrent Childhood Medulloblastoma
Interventions: Other: Laboratory Biomarker Analysis;   Other: Pharmacological Study;   Drug: Vismodegib
13 Not yet recruiting Reduced Craniospinal Radiation Therapy and Chemotherapy in Treating Younger Patients With Newly Diagnosed WNT-Driven Medulloblastoma
Condition: Untreated Childhood Medulloblastoma
Interventions: Drug: Cisplatin;   Drug: Cyclophosphamide;   Other: Laboratory Biomarker Analysis;   Drug: Lomustine;   Radiation: Radiation Therapy;   Drug: Vincristine Sulfate
14 Recruiting Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed, Non-Metastatic Desmoplastic Medulloblastoma
Condition: Untreated Childhood Medulloblastoma
Interventions: Drug: Vincristine Sulfate;   Drug: Cyclophosphamide;   Drug: Methotrexate;   Drug: Etoposide;   Drug: Carboplatin;   Other: Laboratory Biomarker Analysis;   Other: Cognitive Assessment
15 Completed GDC-0449 in Treating Young Patients With Medulloblastoma That is Recurrent or Did Not Respond to Previous Treatment
Condition: Recurrent Childhood Medulloblastoma
Interventions: Drug: vismodegib;   Other: laboratory biomarker analysis;   Other: pharmacological study
16 Completed Comparison of Radiation Therapy Regimens in Combination With Chemotherapy in Treating Young Patients With Newly Diagnosed Standard-Risk Medulloblastoma
Condition: Untreated Childhood Medulloblastoma
Interventions: Drug: Cisplatin;   Radiation: Craniospinal Irradiation;   Drug: Cyclophosphamide;   Radiation: Involved-Field Radiation Therapy;   Other: Laboratory Biomarker Analysis;   Drug: Lomustine;   Other: Quality-of-Life Assessment;   Radiation: Radiation Therapy;   Drug: Vincristine Sulfate
17 Withdrawn A Study of LY2940680 in Pediatric Medulloblastoma or Rhabdomyosarcoma
Conditions: Medulloblastoma, Childhood;   Rhabdomyosarcoma
Intervention: Drug: LY2940680
18 Recruiting Study of Vismodegib in Combination With Temozolomide Versus Temozolomide Alone in Patients With Medulloblastomas With an Activation of the Sonic Hedgehog Pathway
Conditions: Histologically Confirmed Medulloblastoma;   Activation of the Sonic Hedgehog (SHH) Pathway
Interventions: Drug: vismodegib;   Drug: Temozolomide
19 Recruiting Vaccine Immunotherapy for Recurrent Medulloblastoma and Primitive Neuroectodermal Tumor
Conditions: Medulloblastoma;   Neuroectodermal Tumor
Interventions: Biological: TTRNA-xALT;   Biological: TTRNA-DCs
20 Terminated
Has Results
Safety and Efficacy Study of TPI-287 in Neuroblastoma and Medulloblastoma
Conditions: Neuroblastoma;   Medulloblastoma
Intervention: Drug: TPI 287

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Study has passed its completion date and status has not been verified in more than two years.