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135 studies found for:    "Lipodystrophy"
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Rank Status Study
1 Completed Trial of Leptin Replacement Therapy in Patients With Lipodystrophy
Conditions: Hypoleptinemia;   Generalized Lipodystrophy;   Partial Lipodystrophy;   Insulin Resistance
Interventions: Drug: Leptin;   Drug: Placebo
2 Recruiting Lipodystrophy Connect Patient Registry
Condition: Lipodystrophy
Intervention:
3 Completed Therapeutic Approaches to HAART-Induced Lipodystrophy
Conditions: HIV Infections;   Lipodystrophy
Intervention: Drug: Metreleptin (Leptin)
4 Enrolling by invitation Compassionate Use of Metreleptin in Previously Treated People With Generalized Lipodystrophy
Conditions: Lipodystrophy;   Diabetes;   Hyperlipidemia
Intervention: Drug: Metreleptin
5 Completed
Has Results
Leptin to Treat Lipodystrophy
Condition: Lipodystrophy
Intervention: Drug: Metreleptin
6 Completed Corticosteroid-induced Lipodystrophy and Adipokines
Condition: Lipodystrophy
Intervention: Other: Samples and procedures
7 Completed Identification of a New Gene Involved in Hereditary Lipodystrophy
Condition: Lipodystrophy
Interventions: Genetic: Amplification by PCR and direct sequencing on the entire coding sequence and intron-exons boundaries of the candidate gene;   Biological: Perform blood cells and fibroblasts biochemical and immuno-labeled investigations
8 Recruiting Short-term Effects of Leptin in People With Lipodystrophy
Condition: Lipodystrophy
Intervention: Biological: Metreleptin
9 Unknown  Autologous Adipose-Derived Stem Cell Transplantation in Patients With Lipodystrophy
Condition: Lipodystrophy
Intervention: Procedure: autologous transplantation of liposuction material enriched with adipose-derived stem cells
10 Enrolling by invitation Compassionate Use of Metreleptin in Previously Treated People With Partial Lipodystrophy
Conditions: Diabetes;   Lipodystrophy;   Hyperlipidemia
Intervention: Drug: Metreleptin
11 Completed Strategies of Interruption/Reinitiation of Antiretroviral Therapy in HIV-Infected Patients With Lipodystrophy
Condition: HIV-Associated Lipodystrophy Syndrome
Interventions: Drug: Standard continuous antiretroviral therapy;   Drug: CD-4 guided therapy interruption;   Drug: Viral load driven treatment interruption
12 Recruiting Efficacy, Safety and Tolerability of ISIS 304801 in People With Partial Lipodystrophy With an Open-Label Extension
Condition: Lipodystrophy
Interventions: Drug: ISIS 304801;   Drug: Placebo
13 Completed An Open-Label Treatment Protocol to Provide Metreleptin for the Treatment of Diabetes Mellitus and/or Hypertriglyceridemia Associated With Lipodystrophy
Condition: Lipodystrophy
Intervention: Drug: metreleptin
14 Active, not recruiting Clinical Protocol to Investigate the Efficacy of Recombinant Human Leptin (Metreleptin) in Nonalcoholic Steatohepatitis (NASH) or Nonalcoholic Fatty Liver Disease (NAFLD) Associated With Lipodystrophy
Conditions: Fatty Liver Disease, Nonalcoholic;   Nonalcoholic Steatohepatitis;   Lipodystrophy
Intervention: Drug: Metreleptin
15 Unknown  Randomized, Placebo-Controlled Study of Leptin for the Treatment of HIV Lipodystrophy and Metabolic Syndrome
Condition: HAART-induced Lipodystrophy and Metabolic Syndrome
Intervention: Drug: r-metHuLeptin
16 Recruiting Familial Partial Lipodystrophy Study
Condition: Lipodystrophy, Familial Partial
Intervention: Other: High fat mixed meal
17 Completed
Has Results
Study of Reyataz in HIV-infected Patients With Lipodystrophy Syndrome
Condition: HIV-Associated Lipodystrophy Syndrome
Interventions: Drug: Atazanavir (ATV) + ritonavir (RTV), continuation of backbone 2 nucleoside reverse transcriptase inhibitor (NRTIs);   Drug: continuation of current HAART (boosted protease inhibitor [PI] combination + 2 NRTIs)
18 Completed
Has Results
Leptin for Abnormal Lipid Kinetics in HIV Lipodystrophy Syndrome
Condition: HIV Lipodystrophy
Interventions: Drug: Human recombinant leptin ("metreleptin");   Drug: Placebo
19 Terminated Facial Lipoatrophy Trial: Immediate Versus Deferred Injections of Poly-L-Lactic Acid for HIV Facial Lipoatrophy
Conditions: HIV-Associated Lipodystrophy;   HIV Infections
Intervention: Device: poly-L-lactic acid
20 Recruiting Phase 2 Study of Obeticholic Acid for Lipodystrophy Patients
Condition: Familial Partial Lipodystrophy
Interventions: Drug: Obeticholic Acid;   Drug: Placebo

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Indicates status has not been verified in more than two years