41 studies found for:    "Li Fraumeni syndrome"
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Rank Status Study
21 Completed Gene Therapy in Treating Patients With Recurrent Malignant Gliomas
Condition: Brain and Central Nervous System Tumors
Interventions: Biological: Ad5CMV-p53 gene;   Procedure: conventional surgery
22 Recruiting Tissue Banking Study - Polycythemia Vera or Essential Thrombocythemia (PV & ET) Patients
Conditions: Polycythemia Vera;   Essential Thrombocythemia
Intervention: Procedure: Blood specimen
23 Completed Genetic Polymorphisms Associated With Cigarette Smoking and Risk of Graves’ Disease
Condition: Graves' Disease
Intervention:
24 Unknown  Gene Therapy in Treating Patients With Advanced Recurrent or Persistent Ovarian Cancer or Primary Peritoneal Cancer
Conditions: Ovarian Cancer;   Peritoneal Cavity Cancer
Intervention: Biological: Ad5CMV-p53 gene
25 Recruiting Phase II Study of Combined Temozolomide and SGT-53 for Treatment of Recurrent Glioblastoma
Condition: GLIOBLASTOMA
Interventions: Genetic: SGT-53;   Drug: Temozolomide
26 Recruiting Study of Combined SGT-53 Plus Gemcitabine/Nab-Paclitaxel for Metastatic Pancreatic Cancer
Condition: Metastatic Pancreatic Cancer
Interventions: Genetic: SGT-53;   Drug: nab-paclitaxel;   Drug: Gemcitabine
27 Recruiting p53 and Response to Preoperative Radiotherapy for T2 and T3
Condition: Rectal Cancer
Intervention: Radiation: preoperative short course radiation
28 Unknown  Duct Endoscopy in Assessing Cellular Atypia in the Breast Duct Fluid of Women With a Genetic Risk for Breast Cancer
Condition: Breast Cancer
Interventions: Genetic: cytogenetic analysis;   Genetic: proteomic profiling;   Other: cytology specimen collection procedure;   Other: immunohistochemistry staining method;   Other: laboratory biomarker analysis;   Procedure: breast duct lavage
29 Recruiting Safety Study of ALRN-6924 in Patients With Advanced Solid Tumors or Lymphomas
Conditions: Solid Tumor;   Lymphoma
Intervention: Drug: ALRN-6924
30 Completed Chemotherapy Followed By Vaccine Therapy in Treating Patients With Extensive-Stage Small Cell Lung Cancer
Condition: Lung Cancer
Interventions: Biological: Autologous dendritic cell-adenovirus p53 vaccine;   Drug: Carboplatin;   Drug: Etoposide
31 Completed Gene Therapy in Preventing Cancer in Patients With Premalignant Carcinoma of the Oral Cavity or Pharynx
Conditions: Lip and Oral Cavity Cancer;   Oropharyngeal Cancer;   Stage 0 Lip and Oral Cavity Cancer;   Stage 0 Oropharyngeal Cancer;   Tongue Cancer
Interventions: Biological: Ad5CMV-p53 gene;   Other: laboratory biomarker analysis
32 Active, not recruiting To Immunize Patients With Extensive Stage SCLC Combined With Chemo With or Without All Trans Retinoic Acid
Condition: Small Cell Lung Cancer
Interventions: Drug: Paclitaxel;   Biological: Drug: Ad.p53-DC vaccines;   Drug: All -trans Retinoic Acid (ATRA)
33 Active, not recruiting Clinical, Genetic, Behavioral, Laboratory and Epidemiologic Characterization of Individuals and Families at High Risk of Breast/Ovarian Cancer
Conditions: Familial Ovarian Cancer;   Familial Breast Cancer;   BRCA1-associate Malignancies;   BRCA2-associated Malignancies
Intervention:
34 Completed Study of ALT-801 With Cisplatin in Patients With Metastatic Melanoma
Condition: Metastatic Melanoma
Interventions: Drug: Cisplatin;   Biological: ALT-801
35 Completed
Has Results
Safety and Efficacy Study of ALT-801 to Treat Progressive Metastatic Malignancies
Condition: Progressive Metastatic Malignancies
Intervention: Biological: ALT-801
36 Terminated A Study of ALT-801 in Patients With Relapsed or Refractory Multiple Myeloma
Condition: Relapsed or Refractory Multiple Myeloma
Intervention: Biological: ALT-801
37 Active, not recruiting A Study of ALT-801 in Patients With Bacillus Calmette-Guerin (BCG) Failure Non-Muscle Invasive Bladder Cancer
Condition: Non-muscle Invasive Bladder Cancer
Interventions: Biological: ALT-801;   Drug: Gemcitabine
38 Active, not recruiting A Study of ALT-801 in Combination With Cisplatin and Gemcitabine in Muscle Invasive or Metastatic Urothelial Cancer
Conditions: Transitional Cell Carcinoma of Bladder;   Urethra Cancer;   Ureter Cancer;   Malignant Tumor of Renal Pelvis
Interventions: Drug: Cisplatin;   Drug: Gemcitabine;   Biological: ALT-801
39 Recruiting Trial of Adoptive T Cell Therapy With Activated P53 Specific T Cells for Treatment of Advanced Colorectal Cancer
Condition: Colorectal Carcinoma
Intervention: Biological: re-activated T cells
40 Withdrawn Aezea® (Cenersen) and Chemotherapy for AML Subjects ≥ 55 Years of Age With No Response to Frontline Induction Course
Condition: Acute Myelogenous Leukemia
Interventions: Drug: cenersen;   Drug: placebo;   Drug: idarubicin, cytarabine

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Indicates status has not been verified in more than two years