8 studies found for:    "Leigh syndrome"
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"Leigh syndrome" (8 records)
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Rank Status Study
1 Completed Safety and Efficacy Study of EPI-743 in Children With Leigh Syndrome
Condition: Leigh Syndrome
Interventions: Drug: Placebo;   Drug: EPI-743 15 mg/kg;   Drug: EPI-743 5 mg/kg
2 Enrolling by invitation Long-Term Safety and Efficacy Evaluation of EPI-743 in Children With Leigh Syndrome
Condition: Leigh Syndrome
Intervention: Drug: EPI-743
3 Enrolling by invitation Open-Label, Dose-Escalating Study to Assess Safety, Tolerability, Efficacy, PK and PD of RP103 in Children With Inherited Mitochondrial Disease
Condition: Inherited Mitochondrial Disease, Including Leigh Syndrome
Intervention: Drug: Cysteamine Bitartrate Delayed-release Capsules (RP103)
4 Completed A Dose-escalating Clinical Trial With KH176
Conditions: MELAS;   LHON;   Leigh Syndrome;   Mitochondrial Disease;   Mitochondrial DNA tRNALeu(UUR) m.3243A<G Mutation
Interventions: Drug: KH176;   Drug: placebo
5 Recruiting Tissue Sample Study for Mitochondrial Disorders
Conditions: Mitochondrial Disorders;   Mitochondrial Disease;   Melas;   Kearns Sayer;   NARP;   MNGIE;   LHON;   Mitochondrial Depletion Syndrome;   Leigh's Disease
Intervention:
6 Recruiting North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)
Conditions: Mitochondrial Disorders;   Mitochondrial Genetic Disorders;   Mitochondrial Diseases;   Disorder of Mitochondrial Respiratory Chain Complexes;   Deletion and Duplication of Mitochondrial DNA
Intervention:
7 Active, not recruiting EPI-743 for Mitochondrial Respiratory Chain Diseases
Condition: Mitochondrial Diseases
Intervention: Drug: EPI-743
8 Enrolling by invitation A Long-Term Extension Study of RP103-MITO-001 to Assess RP103 in Children With Inherited Mitochondrial Disease
Condition: Mitochondrial Diseases
Intervention: Drug: Cysteamine Bitartrate Delayed-release Capsules

Indicates status has not been verified in more than two years