32 studies found for:    "Langerhans cell histiocytosis"
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Rank Status Study
1 Recruiting Phase II Study of Clofarabine in Patients With Recurrent or Refractory Langerhans Cell Histiocytosis
Condition: Langerhans Cell Histiocytosis
Intervention: Drug: Clofarabine
2 Recruiting Methotrexate and Cytosine in Adult Langerhans Cell Histiocytosis
Condition: Langerhans Cell Histiocytosis
Intervention: Drug: methotrexate
3 Recruiting LCH-IV, International Collaborative Treatment Protocol for Children and Adolescents With Langerhans Cell Histiocytosis
Condition: Langerhans Cell Histiocytosis
Interventions: Drug: Prednisone;   Drug: Vinblastine;   Drug: mercaptopurine;   Drug: INDOMETHACIN;   Drug: Methotrexate;   Drug: Cytosine Arabinoside;   Drug: 2-chlorodeoxyadenosine;   Procedure: hematopoietic stem cell transplantation (RIC-HSCT);   Biological: Intravenous immunoglobulin
4 Not yet recruiting Vinblastine/Prednisone Versus Single Therapy With Cytarabine for Langerhans Cell Histiocytosis (LCH)
Condition: Langerhans Cell Histiocytosis
Interventions: Drug: Cytarabine;   Drug: Vinblastine/prednisone
5 Completed Combination Chemotherapy in Treating Young Patients With Langerhans Cell Histiocytosis
Condition: Childhood Langerhans Cell Histiocytosis
Interventions: Drug: leucovorin calcium;   Drug: methotrexate;   Drug: prednisolone;   Drug: vinblastine sulfate
6 Completed Evaluation of Outcome of Adult Pulmonary Langerhans Cell Histiocytosis Based on Lung HRCT and Lung Function
Condition: Pulmonary Langerhans Cell Histiocytosis
Intervention:
7 Not yet recruiting Evaluation of Exercise Capacity and Exercise Limitation in Patients With Pulmonary Langerhans Cell Histiocytosis
Condition: Langerhans Cell Histiocytosis
Intervention:
8 Unknown  A Study to Test the Ability of and Safety of GSK2110183 in Treating Langerhans Cell Histiocytosis
Condition: Langerhans Cell Histiocytosis
Intervention: Drug: GSK2110183
9 Recruiting Evaluation of Efficacy and Tolerance of Cladribine in Symptomatic Pulmonary Langerhans Cell Histiocytosis
Condition: Langerhans Cell Histiocytosis of Lung
Intervention: Drug: Cladribine
10 Completed Prospective Evaluation of Adult Pulmonary Langerhans Cell Histiocytosis
Condition: Adult Pulmonary Langerhans Cell Histiocytosis
Intervention: Behavioral: Tabacco discontinuation
11 Terminated Blood Stem Cell Transplant in Treating Patients With Hematologic Cancer
Conditions: Adult Langerhans Cell Histiocytosis;   Childhood Langerhans Cell Histiocytosis;   Leukemia;   Lymphoma;   Multiple Myeloma and Plasma Cell Neoplasm;   Myelodysplastic Syndromes;   Myelodysplastic/Myeloproliferative Neoplasms
Intervention: Procedure: Peripheral Blood Stem Cell Transplantation
12 Withdrawn Clofarabine for Langerhans in Pedi
Condition: Langerhans Cell Histiocytosis
Intervention: Drug: Clofarabine
13 Completed
Has Results
Study of Sequential Administration of Oral 6-Thioguanine After Methotrexate in Patients With LCH
Condition: Langerhans Cell Histiocytosis
Interventions: Drug: Methotrexate;   Drug: 6-Thioguanine;   Drug: Leucovorin Calcium
14 Recruiting A Study of Lenalidomide for Adult Histiocyte Disorders
Conditions: Langerhans Cell Histiocytosis (LCH);   Histiocytoses Erdheim-chester Disease;   Histiocytic Sarcoma (HS)
Intervention: Drug: Lenalidomide
15 Recruiting CD34+ Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation for Non-Malignant Disease
Conditions: Bone Marrow Failure Syndrome;   Severe Aplastic Anemia;   Severe Congenital Neutropenia;   Amegakaryocytic Thrombocytopenia;   Diamond-Blackfan Anemia;   Schwachman Diamond Syndrome;   Primary Immunodeficiency Syndromes;   Acquired Immunodeficiency Syndromes;   Histiocytic Syndrome;   Familial Hemophagocytic Lymphocytosis;   Lymphohistiocytosis;   Macrophage Activation Syndrome;   Langerhans Cell Histiocytosis (LCH);   Hemoglobinopathies;   Sickle Cell Disease;   Sickle Cell-beta-thalassemia
Intervention: Biological: CD34 Stem Cell Selection Therapy
16 Unknown  Umbilical Cord Blood for Stem Cell Transplantation in Treating Young Patients With Malignant or Nonmalignant Diseases
Conditions: Childhood Langerhans Cell Histiocytosis;   Fanconi Anemia;   Leukemia;   Lymphoma;   Myelodysplastic Syndromes;   Neuroblastoma;   Sarcoma;   Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: Biological: anti-thymocyte globulin;   Drug: busulfan;   Drug: cyclophosphamide;   Drug: fludarabine phosphate;   Drug: melphalan;   Drug: methylprednisolone;   Radiation: radiation therapy
17 Unknown  Umbilical Cord Blood and Placental Blood Transplantation in Treating Patients With Hematologic Cancer or Aplastic Anemia
Conditions: Childhood Langerhans Cell Histiocytosis;   Leukemia;   Lymphoma;   Multiple Myeloma and Plasma Cell Neoplasm;   Myelodysplastic Syndromes;   Myelodysplastic/Myeloproliferative Neoplasms
Intervention: Procedure: umbilical cord blood transplantation
18 Terminated Indium In 111 Pentetreotide in Treating Patients With Refractory Cancer
Conditions: Brain and Central Nervous System Tumors;   Childhood Langerhans Cell Histiocytosis;   Gastrointestinal Carcinoid Tumor;   Head and Neck Cancer;   Intraocular Melanoma;   Islet Cell Tumor;   Kidney Cancer;   Lung Cancer;   Melanoma (Skin);   Neoplastic Syndrome;   Neuroendocrine Carcinoma of the Skin;   Pheochromocytoma
Intervention: Radiation: indium In 111 pentetreotide
19 Terminated
Has Results
Reduced Intensity Hematopoietic Cell Transplantation for Patients With Resistant Langerhans Cell Histiocytosis
Condition: Histiocytosis, Langerhans-cell
Interventions: Biological: alemtuzumab;   Drug: fludarabine phosphate;   Drug: melphalan;   Procedure: stem cell transplantation
20 Recruiting Uptake and Biodistribution of 18F-fluorocholine in Histiocytic Disorders by PET Imaging and Biopsy Measurement
Conditions: Erdheim-Chester Disease;   Langerhans Cell Histiocytosis;   Histiocytic Disorders
Interventions: Radiation: F-choline PET Scan;   Device: FDG-PET;   Procedure: biopsy

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