87 studies found for:    "Histiocytosis, Langerhans-Cell"
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Rank Status Study
1 Completed Treatment of Resistant Langerhans Cell Histiocytosis With ENBREL
Condition: Histiocytosis, Langerhans-Cell
Intervention: Drug: Etanercept
2 Terminated Reduced Intensity Hematopoietic Cell Transplantation for Patients With Resistant Langerhans Cell Histiocytosis
Condition: Histiocytosis, Langerhans-cell
Interventions: Biological: alemtuzumab;   Drug: fludarabine phosphate;   Drug: melphalan;   Procedure: stem cell transplantation
3 Unknown  Cardiovascular Risk Factors and LCH in Adults
Condition: Histiocytosis, Langerhans-Cell
4 Not yet recruiting Phase II Study of Clofarabine in Patients With Recurrent or Refractory Langerhans Cell Histiocytosis
Condition: Langerhans Cell Histiocytosis
Intervention: Drug: Clofarabine
5 Recruiting Methotrexate and Cytosine in Adult Langerhans Cell Histiocytosis
Condition: Langerhans Cell Histiocytosis
Intervention: Drug: methotrexate
6 Recruiting LCH-IV, International Collaborative Treatment Protocol for Children and Adolescents With Langerhans Cell Histiocytosis
Condition: Langerhans Cell Histiocytosis
Interventions: Drug: Prednisone;   Drug: Vinblastine;   Drug: mercaptopurine;   Drug: INDOMETHACIN;   Drug: Methotrexate;   Drug: Cytosine Arabinoside;   Drug: 2-chlorodeoxyadenosine;   Procedure: hematopoietic stem cell transplantation (RIC-HSCT);   Biological: Intravenous immunoglobulin
7 Completed Combination Chemotherapy in Treating Young Patients With Langerhans Cell Histiocytosis
Condition: Childhood Langerhans Cell Histiocytosis
Interventions: Drug: leucovorin calcium;   Drug: methotrexate;   Drug: prednisolone;   Drug: vinblastine sulfate
8 Completed Evaluation of Outcome of Adult Pulmonary Langerhans Cell Histiocytosis Based on Lung HRCT and Lung Function
Condition: Pulmonary Langerhans Cell Histiocytosis
9 Not yet recruiting A Study of Lenalidomide for Adult Histiocyte Disorders
Conditions: Langerhans Cell Histiocytosis (LCH);   Histiocytoses Erdheim-chester Disease;   Histiocytic Sarcoma (HS)
Intervention: Drug: Lenalidomide
10 Unknown  A Study to Test the Ability of and Safety of GSK2110183 in Treating Langerhans Cell Histiocytosis
Condition: Langerhans Cell Histiocytosis
Intervention: Drug: GSK2110183
11 Recruiting Evaluation of Efficacy and Tolerance of Cladribine in Symptomatic Pulmonary Langerhans Cell Histiocytosis
Condition: Langerhans Cell Histiocytosis of Lung
Intervention: Drug: Cladribine
12 Completed Prospective Evaluation of Adult Pulmonary Langerhans Cell Histiocytosis
Condition: Adult Pulmonary Langerhans Cell Histiocytosis
Intervention: Behavioral: Tabacco discontinuation
13 Completed
Has Results
Study of Sequential Administration of Oral 6-Thioguanine After Methotrexate in Patients With LCH
Condition: Langerhans Cell Histiocytosis
Interventions: Drug: Methotrexate;   Drug: 6-Thioguanine;   Drug: Leucovorin Calcium
14 Terminated Blood Stem Cell Transplant in Treating Patients With Hematologic Cancer
Conditions: Adult Langerhans Cell Histiocytosis;   Childhood Langerhans Cell Histiocytosis;   Leukemia;   Lymphoma;   Multiple Myeloma and Plasma Cell Neoplasm;   Myelodysplastic Syndromes;   Myelodysplastic/Myeloproliferative Neoplasms
Intervention: Procedure: Peripheral Blood Stem Cell Transplantation
15 Recruiting CD34+ Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation for Non-Malignant Disease
Conditions: Bone Marrow Failure Syndrome;   Severe Aplastic Anemia;   Severe Congenital Neutropenia;   Amegakaryocytic Thrombocytopenia;   Diamond-Blackfan Anemia;   Schwachman Diamond Syndrome;   Primary Immunodeficiency Syndromes;   Acquired Immunodeficiency Syndromes;   Histiocytic Syndrome;   Familial Hemophagocytic Lymphocytosis;   Lymphohistiocytosis;   Macrophage Activation Syndrome;   Langerhans Cell Histiocytosis (LCH);   Hemoglobinopathies;   Sickle Cell Disease;   Sickle Cell-beta-thalassemia
Intervention: Biological: CD34 Stem Cell Selection Therapy
16 Withdrawn Clofarabine for Langerhans in Pedi
Condition: Langerhans Cell Histiocytosis
Intervention: Drug: Clofarabine
17 Active, not recruiting Stem Cell Transplant for Immunologic or Histiocytic Disorders
Conditions: Hemophagocytic Lymphohistiocytosis;   X-Linked Lymphoproliferative Disorders;   Chediak-Higashi Syndrome;   Griscelli Syndrome;   Immunologic Deficiency Syndromes;   Langerhans-Cell Histiocytosis
Interventions: Procedure: Stem Cell Transplant;   Drug: Fludarabine, melphalan, ATG or Campath
18 Active, not recruiting
Has Results
T-Cell Depletion and Stem Cell Transplant for Immune Deficiencies and Histiocytic Disorders
Conditions: Hemophagocytic Lymphohistiocytosis;   X-Linked Lymphoproliferative Disorders;   Chediak-Higashi Syndrome;   Griscelli Syndrome;   Immunologic Diseases;   Langerhans-Cell Histiocytosis;   Hematologic Diseases
Interventions: Procedure: Stem Cell Transplant;   Drug: Myeloablative conditioning regimen
19 Recruiting Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune Deficiencies
Conditions: SCID;   Omenn's Syndrome;   Reticular Dysgenesis;   Wiskott-Aldrich Syndrome;   Bare Lymphocyte Syndrome;   Common Variable Immunodeficiency;   Chronic Granulomatous Disease;   CD40 Ligand Deficiency;   Hyper IgM Syndrome;   X-linked Lymphoproliferative Disease;   Hemophagocytic Lymphohistiocytosis;   Griscelli Syndrome;   Chediak-Higashi Syndrome;   Langerhan's Cell Histiocytosis
Interventions: Drug: Alemtuzumab 0.3 mg;   Drug: Cyclophosphamide;   Drug: Busulfan;   Biological: Stem Cell Transplantation;   Drug: Fludarabine phosphate 40 mg;   Drug: Melphalan;   Drug: Alemtuzumab 0.2 mg;   Drug: Fludarabine  phosphate 30 mg;   Drug: MESNA
20 Terminated Phase I/IIa Study to Evaluate the Safety, PK, PD, and Preliminary Efficacy of PLX8394 in Patients With Advanced Cancers.
Conditions: Melanoma;   Thyroid Cancer;   Colorectal Cancer;   Non-small Cell Lung Cancer;   Cholangiocarcinoma;   Histiocytosis;   Hairy Cell Leukemia
Intervention: Drug: PLX8394

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Indicates status has not been verified in more than two years