1683 studies found for:    "Glioma"
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Rank Status Study
1 Recruiting A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas
Conditions: Pilomyxoid Astrocytoma;   Pilocytic Astrocytoma;   Glioma, Astrocytic;   Optic Nerve Glioma;   Pleomorphic Xanthoastrocytoma;   Glioblastoma Multiforme;   Anaplastic Astrocytoma;   Gliosarcoma;   Diffuse Intrinsic Pontine Glioma;   DIPG;   Low-grade Glioma;   Brainstem Glioma
Interventions: Drug: Mebendazole;   Drug: Vincristine;   Drug: Carboplatin;   Drug: Temozolomide;   Drug: Bevacizumab;   Drug: Irinotecan
2 Recruiting Proton Radiation Therapy for Gliomas
Conditions: Low Grade Glioma;   WHO Grade 3 Glioma With IDH1 Mutation;   WHO Grade 3 Glioma With 1p/19q Codeletion
Intervention: Radiation: Proton radiation
3 Terminated 18F FDOPA PET/CT or PET/MRI in Measuring Tumors in Patients With Newly Diagnosed or Recurrent Gliomas
Conditions: Adult Anaplastic Ependymoma;   Adult Anaplastic Oligodendroglioma;   Adult Brain Stem Glioma;   Adult Diffuse Astrocytoma;   Adult Giant Cell Glioblastoma;   Adult Glioblastoma;   Adult Gliosarcoma;   Adult Mixed Glioma;   Adult Oligodendroglioma;   Adult Pilocytic Astrocytoma;   Adult Pineal Gland Astrocytoma;   Adult Subependymal Giant Cell Astrocytoma;   Childhood High-grade Cerebellar Astrocytoma;   Childhood High-grade Cerebral Astrocytoma;   Childhood Low-grade Cerebellar Astrocytoma;   Childhood Low-grade Cerebral Astrocytoma;   Recurrent Adult Brain Tumor;   Recurrent Childhood Anaplastic Astrocytoma;   Recurrent Childhood Anaplastic Oligoastrocytoma;   Recurrent Childhood Anaplastic Oligodendroglioma;   Recurrent Childhood Brain Stem Glioma;   Recurrent Childhood Cerebellar Astrocytoma;   Recurrent Childhood Cerebral Astrocytoma;   Recurrent Childhood Diffuse Astrocytoma;   Recurrent Childhood Fibrillary Astrocytoma;   Recurrent Childhood Gemistocytic Astrocytoma;   Recurrent Childhood Giant Cell Glioblastoma;   Recurrent Childhood Glioblastoma;   Recurrent Childhood Gliomatosis Cerebri;   Recurrent Childhood Gliosarcoma;   Recurrent Childhood Oligoastrocytoma;   Recurrent Childhood Oligodendroglioma;   Recurrent Childhood Pilomyxoid Astrocytoma;   Recurrent Childhood Protoplasmic Astrocytoma;   Recurrent Childhood Subependymal Giant Cell Astrocytoma;   Recurrent Childhood Visual Pathway and Hypothalamic Glioma;   Recurrent Childhood Visual Pathway Glioma;   Untreated Childhood Anaplastic Astrocytoma;   Untreated Childhood Anaplastic Oligoastrocytoma;   Untreated Childhood Anaplastic Oligodendroglioma;   Untreated Childhood Brain Stem Glioma;   Untreated Childhood Cerebellar Astrocytoma;   Untreated Childhood Cerebral Astrocytoma;   Untreated Childhood Diffuse Astrocytoma;   Untreated Childhood Fibrillary Astrocytoma;   Untreated Childhood Gemistocytic Astrocytoma;   Untreated Childhood Giant Cell Glioblastoma;   Untreated Childhood Glioblastoma;   Untreated Childhood Gliomatosis Cerebri;   Untreated Childhood Gliosarcoma;   Untreated Childhood Oligoastrocytoma;   Untreated Childhood Oligodendroglioma;   Untreated Childhood Pilomyxoid Astrocytoma;   Untreated Childhood Protoplasmic Astrocytoma;   Untreated Childhood Subependymal Giant Cell Astrocytoma;   Untreated Childhood Visual Pathway and Hypothalamic Glioma;   Untreated Childhood Visual Pathway Glioma
Interventions: Drug: fluorine F 18 fluorodopa;   Procedure: positron emission tomography;   Procedure: computed tomography;   Procedure: magnetic resonance imaging
4 Recruiting Intraarterial Infusion Of Erbitux and Bevacizumab For Relapsed/Refractory Intracranial Glioma In Patients Under 22
Conditions: Glioblastoma Multiforme;   Fibrillary Astrocytoma of Brain;   Glioma of Brainstem;   Anaplastic Astrocytoma;   Pilomyxoid Astrocytoma;   Mixed Oligodendroglioma-Astrocytoma;   Brain Stem Glioma;   Diffuse Intrinsic Pontine Glioma
Intervention: Drug: SIACI of Erbitux and Bevacizumab
5 Recruiting A Pilot Study of Glioma Associated Antigen Vaccines in Conjunction With Poly-ICLC in Pediatric Gliomas
Conditions: Newly Diagnosed Pediatric Pontine Glioma.;   Newly Diagnosed Pediatric High Grade Glioma.;   Recurrent Pediatric High Grade Glioma.;   Recurrent Pediatric Low Grade Glioma.
Interventions: Biological: HLA-A2 restricted glioma antigen peptides vaccine;   Biological: Poly-ICLC
6 Completed AZD8055 for Adults With Recurrent Gliomas
Conditions: Glioblastoma Multiforme;   Anaplastic Astrocytoma;   Anaplastic Oligodendroglioma;   Malignant Glioma;   Brainstem Glioma
Intervention: Drug: AZD8055
7 Recruiting Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma
Conditions: Diffuse Intrinsic Pontine Glioma;   Brainstem Glioma
Intervention:
8 Terminated
Has Results
Ritonavir and Lopinavir in Treating Patients With Progressive or Recurrent High-Grade Glioma
Conditions: Brain Tumor;   Anaplastic Astrocytoma;   Anaplastic Ependymoma;   Anaplastic Oligodendroglioma;   Brain Stem Glioma;   Giant Cell Glioblastoma;   Glioblastoma;   Gliosarcoma;   Mixed Glioma
Interventions: Drug: ritonavir;   Drug: lopinavir
9 Recruiting Dendritic Cell Vaccine For Malignant Glioma and Glioblastoma Multiforme in Adult and Pediatric Subjects
Conditions: Malignant Glioma;   Glioblastoma Multiforme;   Anaplastic Astrocytoma;   High Grade Glioma
Interventions: Biological: Dendritic Cell Vaccine;   Biological: Tumor Lysate;   Other: Imiquimod;   Procedure: Leukapheresis
10 Recruiting Rotating Frame Relaxation and Diffusion Weighted Imaging of Human Gliomas
Conditions: Low Grade Glioma;   Malignant Glioma
Intervention:
11 Completed Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Glucocorticoids, in Combination With Interleukin-2
Conditions: Anaplastic Astrocytoma;   Anaplastic Ependymoma;   Anaplastic Meningioma;   Anaplastic Oligodendroglioma;   Brain Stem Glioma;   Ependymoblastoma;   Giant Cell Glioblastoma;   Glioblastoma;   Gliosarcoma;   Grade III Meningioma;   Meningeal Hemangiopericytoma;   Mixed Glioma;   Pineal Gland Astrocytoma;   Brain Tumor
Interventions: Biological: therapeutic allogeneic lymphocytes;   Biological: aldesleukin;   Other: laboratory biomarker analysis;   Procedure: positron emission tomography
12 Completed
Has Results
Bevacizumab for Recurrent Malignant Glioma
Conditions: Recurrent High-Grade Gliomas;   Malignant Gliomas
Intervention: Drug: Bevacizumab
13 Completed A Study of XL765 (SAR245409) in Combination With Temozolomide With and Without Radiation in Adults With Malignant Gliomas
Conditions: Mixed Gliomas;   Malignant Gliomas;   Glioblastoma Multiforme
Interventions: Drug: XL765 (SAR245409);   Drug: Temozolomide
14 Recruiting Treatment With AZD4547 for Recurrent Malignant Glioma Expressing FGFR-TACC Gene Fusion"
Conditions: Recurrent IDHwt Gliomas With FGFR3-TACC3 Fusion;   Recurrent IDHwt Gliomas With FGFR1-TACC1 Fusion
Intervention: Drug: AZD4547
15 Active, not recruiting Lenalidomide and Radiation Therapy in High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas
Conditions: Diffuse Intrinsic Pontine Glioma;   Anaplastic Astrocytoma;   High Grade Glioma
Interventions: Drug: Lenalidomide;   Radiation: XRT, 54-59.4 Gy
16 Active, not recruiting Topotecan Using Convection-Enhanced Delivery (CED) in High Grade Glioma
Conditions: Malignant Glioma;   WHO Grade III or IV Recurrent Glioma
Interventions: Drug: Topotecan;   Drug: Gadolinium DTPA;   Device: Cleveland Multiport Catheter
17 Completed A Pilot Feasibility Study of Oral 5-Fluorocytosine and Genetically-Modified Neural Stem Cells Expressing E.Coli Cytosine Deaminase for Treatment of Recurrent High Grade Gliomas
Conditions: Adult Anaplastic Astrocytoma;   Recurrent Grade III Glioma;   Recurrent Grade IV Glioma;   Adult Anaplastic Oligodendroglioma;   Adult Brain Tumor;   Adult Giant Cell Glioblastoma;   Adult Glioblastoma;   Adult Gliosarcoma;   Adult Mixed Glioma;   Recurrent Adult Brain Tumor;   Adult Anaplastic Oligoastrocytoma;   Recurrent High Grade Glioma
Interventions: Drug: flucytosine;   Other: polymerase chain reaction;   Other: immunohistochemistry staining method;   Biological: gene therapy;   Other: pharmacological study;   Other: 3-Tesla magnetic resonance imaging;   Other: laboratory biomarker analysis;   Procedure: therapeutic conventional surgery;   Biological: E. coli CD-expressing genetically modified neural stem cells
18 Active, not recruiting Hypofractionated Stereotactic Radiotherapy With Bevacizumab in the Treatment of Recurrent Malignant Glioma
Conditions: Brain Cancer;   MALIGNANT GLIOMA;   Glioblastoma;   Anaplastic Astrocytoma (AA);   Anaplastic Oligodendroglioma (AO);   Anaplastic Oligo-astrocytoma (AOA);   Anaplastic Mixed Gliomas;   Malignant Glioma NOS
Intervention: Other: Bevacizumab & Stereotactic Radiotherapy
19 Recruiting PNOC 001: Phase II Study of Everolimus for Recurrent or Progressive Low-grade Gliomas in Children
Conditions: Pediatric Recurrent Progressive Low-grade Gliomas;   Pediatric Progressive Low-grade Gliomas
Intervention: Drug: Everolimus
20 Active, not recruiting Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma
Conditions: Glioma;   Neurofibromatosis Type 1;   Recurrent Childhood Pilocytic Astrocytoma;   Recurrent Childhood Visual Pathway Glioma
Interventions: Other: Laboratory Biomarker Analysis;   Other: Pharmacological Study;   Drug: Selumetinib

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