- List
- By Topic
- On Map
- Search Details

"Down syndrome"
Need help? See RSS Feeds
Choose a feed type:

"Down syndrome" (192 records)
Need help? See Downloading Content for Analysis
For Advanced Users: Full Study Record XML Download
1 | NCT02895802 | Completed | Assessing the Feasibility of the Use of Visual Aids in Patient Education in Adults With Down Syndrome (DS) |
|
|
Interventional |
Not Applicable |
|
Other |
|
|
40 | All | 18 Years and older (Adult, Older Adult) | NCT02895802 | 6360 | August 2016 | December 2016 | October 25, 2017 | September 12, 2016 | January 23, 2019 |
|
|||
2 | NCT01950624 | Recruiting | DS-Connect {TM}: The Down Syndrome Registry |
|
Observational |
|
NIH |
|
|
100000 | All | Child, Adult, Older Adult | NCT01950624 | 999913201 13-CH-N201 |
September 21, 2013 | August 16, 2019 | August 16, 2020 | September 25, 2013 | August 31, 2018 |
|
|||||
3 | NCT03087500 | Withdrawn | Physiological Abnormalities Associated With Down Syndrome |
|
Observational |
|
Other |
|
|
0 | All | 3 Years to 50 Years (Child, Adult) | NCT03087500 | IRB: #206522 | October 2017 | September 2019 | December 2019 | March 22, 2017 | October 27, 2017 | ||||||
4 | NCT02882698 | Completed | Performance Analysis in Down Syndrome on Mobile Phone |
|
|
Interventional |
Not Applicable |
|
Other |
|
|
100 | All | 11 Years to 35 Years (Child, Adult) | NCT02882698 | 341/1 | September 2016 | November 2016 | December 2016 | August 30, 2016 | April 11, 2017 |
|
|||
5 | NCT01303133 | Completed | Natural History of Amyloid Deposition in Adults With Down Syndrome |
|
Observational |
|
Other / NIH |
|
|
81 | All | 30 Years and older (Adult, Older Adult) | NCT01303133 | PRO09080266 2R01AG031110-03A1 |
August 2009 | March 31, 2018 | March 31, 2018 | February 24, 2011 | January 9, 2019 |
|
|||||
6 | NCT03590665 | Recruiting | Blood Flow in Individuals With Down Syndrome |
|
|
Interventional |
Not Applicable |
|
Other |
|
|
70 | All | 18 Years to 45 Years (Adult) | NCT03590665 | 1K99HD092606-01 | March 1, 2018 | June 1, 2019 | June 1, 2019 | July 18, 2018 | July 18, 2018 |
|
|||
7 | NCT00748007 | Completed | Efficacy of Rivastigmine in Patients With Down Syndrome |
|
|
Interventional |
Not Applicable |
|
Other |
|
|
14 | All | 8 Years and older (Child, Adult, Older Adult) | NCT00748007 | 200709028M | January 2008 | December 2009 | December 2009 | September 8, 2008 | November 28, 2012 |
|
|||
8 | NCT01598350 | Completed Has Results |
Gait in Children With Down Syndrome While Wearing Orthoses |
|
|
Interventional |
Not Applicable |
|
Other |
|
|
6 | All | 2 Years to 10 Years (Child) | NCT01598350 | 0910-003 | January 2010 | June 2011 | June 2011 | May 15, 2012 | December 30, 2013 | December 30, 2013 |
|
||
9 | NCT02094053 | Completed | A Double-blind, Placebo-controlled Comparative Study and Open-label Extension Study to Confirm the Efficacy and Safety of E2020 in Subjects With Down Syndrome Having Regression Symptoms and Disabled Activities of Daily Living. |
|
|
Interventional |
Phase 2 |
|
Industry |
|
|
36 | All | 15 Years to 39 Years (Child, Adult) | NCT02094053 | E2020-J081-345 | September 12, 2013 | September 16, 2016 | April 21, 2017 | March 21, 2014 | August 22, 2017 |
|
|||
10 | NCT01390558 | Completed | Gait Parameters of Persons With Down Syndrome With and Without Orthotics Using GaitRite |
|
|
Observational |
|
Other |
|
|
23 | All | 2 Years to 80 Years (Child, Adult, Older Adult) | NCT01390558 | Gait Parameters Down Syndrome | June 2011 | August 27, 2018 | August 27, 2018 | July 11, 2011 | February 15, 2019 |
|
||||
11 | NCT03267602 | Completed | Role of Sleep Apnea in the Neuropsychological Function in Down Syndrome People |
|
|
Interventional |
Not Applicable |
|
Other |
|
|
45 | All | Child, Adult, Older Adult | NCT03267602 | 201208075RIC | December 2012 | December 2016 | December 2016 | August 30, 2017 | September 5, 2017 | ||||
12 | NCT03058640 | Active, not recruiting | Effects of Karate in Adolescents With Down Syndrome |
|
|
Interventional |
Not Applicable |
|
Other |
|
|
16 | All | 12 Years to 18 Years (Child, Adult) | NCT03058640 | 00116460 | July 15, 2017 | March 31, 2019 | March 31, 2019 | February 23, 2017 | November 6, 2018 |
|
|||
13 | NCT02127515 | Unknown † | Non Invasive Prenatal Testing of Down Syndrome |
|
|
Interventional |
Not Applicable |
|
Other |
|
|
2450 | Female | 18 Years and older (Adult, Older Adult) | NCT02127515 | P130601 2013-A00998-37 |
SAFE 21 | April 2014 | April 2016 | December 2016 | April 30, 2014 | November 13, 2015 |
|
||
14 | NCT03192540 | Active, not recruiting | The Impact of an 8-week Supported Exercise Program on Fitness and Symptoms in Adolescents With Down Syndrome |
|
|
Interventional |
Not Applicable |
|
Other |
|
|
8 | All | 12 Years to 17 Years (Child) | NCT03192540 | P00023661 | DSFIT | September 15, 2018 | January 12, 2019 | January 31, 2019 | June 20, 2017 | November 21, 2018 |
|
||
15 | NCT00844259 | Completed | Functional Communicative Profile of Children With Down Syndrome |
|
Observational |
|
Other |
|
15 | All | 5 Years to 8 Years (Child) | NCT00844259 | 180875 | July 2006 | October 2007 | October 2007 | February 16, 2009 | February 16, 2009 |
|
||||||
16 | NCT02719600 | Completed | Motor Learning Through Virtual Reality Task in Individuals With Down Syndrome |
|
|
Interventional |
Not Applicable |
|
Other |
|
|
40 | All | 11 Years to 28 Years (Child, Adult) | NCT02719600 | 1033/03 | March 2015 | March 2016 | March 2016 | March 25, 2016 | March 25, 2016 | ||||
17 | NCT01663675 | Recruiting | Trisomy 21 in Adulthood |
|
|
Observational |
|
Other |
|
80 | All | 18 Years and older (Adult, Older Adult) | NCT01663675 | 5249 | November 2014 | October 2019 | October 2019 | August 13, 2012 | November 23, 2016 |
|
|||||
18 | NCT01758718 | Completed | Eyelash Line Resection for Entropion Associated With Down's Syndrome |
|
|
Interventional |
Not Applicable |
|
Other |
|
|
24 | All | 3 Years to 90 Years (Child, Adult, Older Adult) | NCT01758718 | Kyorineye009 Entropion with Down's syndrome |
April 2007 | March 2012 | October 2012 | January 1, 2013 | January 1, 2013 |
|
|||
19 | NCT02738450 | Recruiting | Safety, Tolerability and Immunogenicity of ACI-24 Vaccine in Adults With Down Syndrome |
|
|
Interventional |
Phase 1 |
|
Industry / NIH / Other |
|
|
24 | All | 25 Years to 45 Years (Adult) | NCT02738450 | ACI-24-1301 1R01AG047922-01 |
3 Star | March 2016 | March 2020 | March 2021 | April 14, 2016 | May 23, 2018 |
|
||
20 | NCT00952354 | Unknown † | Oral Language in Children With Down Syndrome |
|
Observational |
|
Other |
|
60 | All | 3 Years to 10 Years (Child) | NCT00952354 | 473492/2007-5 CNPq-473492/2007-5 |
August 2007 | April 2009 | August 2009 | August 6, 2009 | August 6, 2009 |
|
||||||
21 | NCT02432716 | Active, not recruiting | Investigation of the Safety of Intranasal Glulisine in Down Syndrome |
|
|
Interventional |
Phase 1 |
|
Other |
|
|
12 | All | 35 Years to 80 Years (Adult, Older Adult) | NCT02432716 | HealthPartnersRF | April 2015 | April 2019 | April 2019 | May 4, 2015 | December 13, 2018 |
|
|||
22 | NCT00954382 | Unknown † | Trends in Intellectual Development in Down Syndrome |
|
Observational |
|
Other |
|
|
60 | All | 3 Months to 40 Years (Child, Adult) | NCT00954382 | 200904037R | May 2009 | December 2009 | December 2010 | August 7, 2009 | March 18, 2010 |
|
|||||
23 | NCT02288702 | Recruiting | Comparison of Bispectral Index Values in Patients With and Without Down's Syndrome |
|
|
Observational |
|
Other |
|
|
50 | All | 2 Years to 17 Years (Child) | NCT02288702 | STUDY00000604 | October 2014 | February 2020 | February 2020 | November 11, 2014 | February 4, 2019 |
|
||||
24 | NCT00891917 | Completed | Liq-NOL Efficacy in Pediatric Patients With Down Syndrome |
|
|
Interventional |
Phase 2 |
|
Other |
|
|
30 | All | 6 Years to 16 Years (Child) | NCT00891917 | 04-12-4 | January 2005 | November 2012 | December 2012 | May 1, 2009 | January 29, 2014 |
|
|||
25 | NCT02481765 | Recruiting | Feasibility and Dose Tolerability of HD-tDCS in Healthy Adults and Children With Down Syndrome |
|
|
Interventional |
Phase 1 |
|
Other |
|
|
10 | All | 18 Years to 45 Years (Adult) | NCT02481765 | 2014-0262 | June 2015 | November 2019 | June 2020 | June 25, 2015 | January 10, 2019 |
|
|||
26 | NCT02484703 | Terminated | A Study of RO5186582 in Down Syndrome Among Children 6 to 11 Years of Age |
|
|
Interventional |
Phase 2 |
|
Industry |
|
|
45 | All | 6 Years to 11 Years (Child) | NCT02484703 | WP28760 | October 28, 2015 | August 3, 2016 | August 3, 2016 | June 30, 2015 | July 6, 2017 |
|
|||
27 | NCT00825175 | Completed Has Results |
Treadmill Training and Orthotic Use in Infants With Down Syndrome |
|
|
Interventional |
Not Applicable |
|
Other |
|
|
22 | All | 6 Months to 36 Months (Child) | NCT00825175 | HUM00002466 | March 2006 | June 2008 | June 2008 | January 19, 2009 | December 4, 2017 | January 24, 2014 |
|
||
28 | NCT02431117 | Completed | Non-drug Study to Assess the Suitability of Assessment Scales in Japanese Individuals With Down Syndrome Aged 6-30 |
|
Observational |
|
Industry |
|
|
43 | All | 6 Years to 30 Years (Child, Adult) | NCT02431117 | JP29688 | June 2015 | July 2016 | July 2016 | April 30, 2015 | July 11, 2016 |
|
|||||
29 | NCT01084135 | Completed Has Results |
Rivastigmine Study in Adolescents With Down Syndrome |
|
|
Interventional |
Phase 1 Phase 2 |
|
Other |
|
|
42 | All | 10 Years to 17 Years (Child) | NCT01084135 | Pro00013682 | DS-Riv | November 2009 | February 2014 | February 2014 | March 10, 2010 | April 6, 2015 | March 12, 2015 |
|
|
30 | NCT02380638 | Completed | Effects of Whole-body Vibration Training on Body Composition in Adolescents With and Without Down Syndrome |
|
|
Interventional |
Not Applicable |
|
Other |
|
|
58 | All | 10 Years to 19 Years (Child, Adult) | NCT02380638 | DEP2009-09183 | January 2010 | June 2012 | December 2012 | March 5, 2015 | March 5, 2015 |
|
|||
31 | NCT00668980 | Completed | Symbolic Representation in Young Children With Down Syndrome |
|
Observational |
|
Other |
|
|
25 | All | Child, Adult, Older Adult | NCT00668980 | 06/50842-4 | July 2006 | April 2009 | April 2009 | April 29, 2008 | January 14, 2010 |
|
|||||
32 | NCT02451657 | Completed | Non-drug Study to Evaluate the Suitability of Neurocognitive Tests and Functioning Scales for the Measurement of Cognitive and Functioning Changes in Children With Down Syndrome |
|
|
Observational |
|
Industry |
|
|
40 | All | 6 Years to 11 Years (Child) | NCT02451657 | BP29589 | June 2, 2015 | June 30, 2016 | June 30, 2016 | May 22, 2015 | October 25, 2017 |
|
||||
33 | NCT01576705 | Completed | Efficacy Assessment of Systematic Treatment With Folinic Acid and Thyroid Hormone on Psychomotor Development of Down Syndrome Young Children |
|
|
Interventional |
Phase 3 |
|
Other |
|
|
175 | All | 6 Months to 18 Months (Child) | NCT01576705 | IJL-AFHT-TH10 | ACTHYF | April 2012 | December 14, 2017 | December 14, 2017 | April 12, 2012 | March 7, 2018 |
|
||
34 | NCT02024789 | Completed | A Study of RG1662 in Adults and Adolescents With Down Syndrome (CLEMATIS) |
|
|
Interventional |
Phase 2 |
|
Industry |
|
|
173 | All | 12 Years to 30 Years (Child, Adult) | NCT02024789 | BP27832 2013-001263-23 |
May 5, 2014 | May 4, 2016 | May 4, 2016 | December 31, 2013 | October 25, 2017 |
|
|||
35 | NCT03783338 | Recruiting | Interaction Effects of Vitamin D Supplementation and Aerobic Exercises on Cognition, Balance and Physical Performance in Children With Down Syndrome |
|
|
Interventional |
Not Applicable |
|
Other |
|
|
45 | All | 8 Years to 12 Years (Child) | NCT03783338 | P.T.REC/012/002143 | December 2, 2018 | March 2, 2019 | March 2, 2019 | December 21, 2018 | December 21, 2018 |
|
|||
36 | NCT00570128 | Completed | Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (Aricept) In Treating Cognitive Dysfunction Exhibited By Children With Down Syndrome |
|
|
Interventional |
Phase 2 |
|
Industry |
|
|
150 | All | 10 Years to 17 Years (Child) | NCT00570128 | E2020-A001-219 | December 2007 | September 2008 | December 2008 | December 10, 2007 | August 6, 2009 |
|
|||
37 | NCT00294593 | Completed | Efficacy Study of Folinic Acid to Improve Mental Development of Children With Down Syndrome |
|
|
Interventional |
Phase 2 Phase 3 |
|
Other |
|
|
120 | All | 3 Months to 30 Months (Child) | NCT00294593 | IJL-FA-TH01 | October 2000 | December 2003 | February 22, 2006 | December 17, 2009 |
|
||||
38 | NCT01920633 | Completed | A Screening Protocol to Assess Adults and Adolescents With Down Syndrome for Eligibility For Upcoming Study of RG1662 (Study BP27832) |
|
Observational |
|
Industry |
|
|
135 | All | 12 Years to 30 Years (Child, Adult) | NCT01920633 | BP28947 2013-001264-33 |
October 31, 2013 | January 31, 2015 | January 31, 2015 | August 12, 2013 | July 19, 2017 |
|
|||||
39 | NCT01112683 | Completed Has Results |
Efficacy and Safety of Memantine Hydrochloride in Enhancing the Cognitive Abilities of Young Adults With Down Syndrome |
|
|
Interventional |
Phase 4 |
|
Other / Industry |
|
|
42 | All | 18 Years to 32 Years (Adult) | NCT01112683 | 06-0934 | July 2008 | July 2011 | August 2011 | April 28, 2010 | February 1, 2013 | February 1, 2013 |
|
||
40 | NCT03553706 | Completed | Indicators of Growth, Nutritional Status and Comorbide Disorders of Newborns With Down Syndrome |
|
Observational |
|
Other |
|
|
141 | All | up to 1 Month (Child) | NCT03553706 | KBC2052018 | DownSy | May 20, 2018 | May 30, 2018 | May 30, 2018 | June 12, 2018 | June 12, 2018 |
|
||||
41 | NCT01436955 | Completed | A Study of RG1662 in Individuals With Down Syndrome |
|
|
Interventional |
Phase 1 |
|
Industry |
|
|
35 | All | 18 Years to 30 Years (Adult) | NCT01436955 | BP25543 | November 2011 | September 2013 | September 2013 | September 20, 2011 | March 3, 2015 |
|
|||
42 | NCT03206957 | Recruiting | Correlation Between Optic Nerve Vessel Anomalies, Serum Angiogenic Factors and Renal Anomalies in Down Syndrome Children |
|
|
Interventional |
Not Applicable |
|
Other |
|
|
200 | All | up to 17 Years (Child) | NCT03206957 | P2017/Ophtalmo/DOPANUR | DOPANUR | November 30, 2017 | June 1, 2019 | June 1, 2019 | July 2, 2017 | July 4, 2018 |
|
||
43 | NCT00695695 | Completed | The Experience of Caregivers of Children With Down Syndrome |
|
Observational |
|
NIH |
|
546 | All | 18 Years and older (Adult, Older Adult) | NCT00695695 | 999908142 08-HG-N142 |
May 14, 2008 | February 3, 2014 | June 12, 2008 | February 8, 2019 |
|
|||||||
44 | NCT00689988 | Completed | Augmentative and Alternative Communication (AAC) and Lexical Gain in Children With Down Syndrome |
|
|
Interventional |
Not Applicable |
|
Other |
|
|
5 | All | 5 Years to 11 Years (Child) | NCT00689988 | 05/1149 | July 2005 | October 2007 | June 2008 | June 4, 2008 | June 4, 2008 |
|
|||
45 | NCT01034280 | Completed | Correlations Phenotype / Genotype in Down Syndrome |
|
Observational |
|
Other |
|
524 | All | 8 Years and older (Child, Adult, Older Adult) | NCT01034280 | IJL-PG-EP03 Intrepid |
INTREPID | March 2004 | May 2011 | December 17, 2009 | March 22, 2012 |
|
||||||
46 | NCT03653143 | Recruiting | JASPER Intervention in Down Syndrome |
|
|
Interventional |
Not Applicable |
|
Other |
|
|
12 | All | 36 Months to 48 Months (Child) | NCT03653143 | IRB-P00025806 | December 1, 2018 | December 1, 2019 | June 1, 2020 | August 31, 2018 | January 31, 2019 |
|
|||
47 | NCT01148121 | Completed | Assessment of Bone Density and Bone Turnover Markers in Patients With Down Syndrome and Comparison to the Ts65Dn Model |
|
|
Interventional |
Not Applicable |
|
Other |
|
|
30 | All | 18 Years and older (Adult, Older Adult) | NCT01148121 | 113810 | June 2010 | August 2015 | August 2015 | June 22, 2010 | December 7, 2016 |
|
|||
48 | NCT00643955 | Unknown † | Neuromuscular Characteristics of Individuals With Down Syndrome (DS) |
|
|
Observational |
|
Other |
|
|
15 | All | 18 Years to 45 Years (Adult) | NCT00643955 | 5495 | March 2008 | March 26, 2008 | March 26, 2008 |
|
||||||
49 | NCT00643552 | Completed | Muscle Strength, Physical Work Capacity and Functional Performance in Individuals With Down Syndrome |
|
Observational |
|
Other |
|
18 | All | 17 Years and older (Child, Adult, Older Adult) | NCT00643552 | 4973 | March 26, 2008 | March 26, 2008 | ||||||||||
50 | NCT01975545 | Unknown † | Fluor Varnish With Silver Nanoparticles for Dental Remineralization in Patients With Trisomy 21 |
|
|
Interventional |
Phase 2 |
|
Other |
|
|
20 | All | 1 Year to 6 Years (Child) | NCT01975545 | MCIC-001 | September 2012 | April 2014 | May 2014 | November 4, 2013 | March 7, 2014 |
|
|||
51 | NCT01256112 | Completed | Parent Supported Weight Reduction in Down Syndrome |
|
|
Interventional |
Not Applicable |
|
NIH / Other |
|
21 | All | 13 Years to 26 Years (Child, Adult) | NCT01256112 | 1 R03 DK070627 (completed) R03DK070627 |
September 2006 | March 2010 | March 2010 | December 8, 2010 | October 18, 2017 |
|
||||
52 | NCT01791725 | Completed Has Results |
A 4-Week Safety Study of Oral ELND005 in Young Adults With Down Syndrome Without Dementia |
|
|
Interventional |
Phase 2 |
|
Industry |
|
|
23 | All | 18 Years to 45 Years (Adult) | NCT01791725 | ELND005-DS201 | DS201 | September 2013 | June 2014 | June 2014 | February 15, 2013 | January 29, 2016 | January 29, 2016 |
|
|
53 | NCT01821300 | Active, not recruiting Has Results |
Down Syndrome Metabolic Health Study |
|
Observational |
|
Other / NIH |
|
|
257 | All | 10 Years to 20 Years (Child, Adult) | NCT01821300 | 12-009233 1R01HD071981-01A1 |
February 2013 | August 25, 2017 | July 1, 2019 | April 1, 2013 | January 31, 2019 | January 9, 2019 |
|
||||
54 | NCT00951730 | Completed | Evaluation of a Simplified Method for Diagnosis of Sleep Apnea in Children and Adults With Down Syndrome |
|
|
Observational |
|
Other |
|
|
97 | All | 2 Years and older (Child, Adult, Older Adult) | NCT00951730 | 0808017 2008-A01273-52 |
SAOS/T21 | February 2010 | February 2015 | February 2015 | August 4, 2009 | July 7, 2015 |
|
|||
55 | NCT01041469 | Completed | Pilot Study of Auto-immune Abnormalities Associated With Down Syndrome |
|
Observational |
|
Other |
|
|
72 | All | 8 Years to 36 Years (Child, Adult) | NCT01041469 | IJL-IMM-EP10 | IMMUTRI | November 2009 | December 2010 | December 31, 2009 | March 22, 2012 |
|
|||||
56 | NCT02996175 | Completed | Treatment of Sleep Disturbances in School-age Children With Down Syndrome |
|
|
Interventional |
Not Applicable |
|
Other |
|
|
34 | All | 6 Years to 17 Years (Child) | NCT02996175 | 1R21HD082307-01A1 | July 2015 | May 2018 | May 2018 | December 19, 2016 | June 4, 2018 |
|
|||
57 | NCT03687619 | Not yet recruiting | Cognitive Orientation to Daily Occupational Performance and Conductive Education Approaches on Down Syndrome |
|
|
Interventional |
Not Applicable |
|
Other |
|
|
10 | All | 7 Years to 18 Years (Child, Adult) | NCT03687619 | ETK00-218-0213 | February 15, 2019 | December 15, 2019 | December 30, 2019 | September 27, 2018 | October 16, 2018 | ||||
58 | NCT03551418 | Recruiting | Learning by Repetitive Viewing of Peer Modeling Patient Education Videos by Adults With Down Syndrome |
|
|
Interventional |
Not Applicable |
|
Other |
|
|
40 | All | 18 Years and older (Adult, Older Adult) | NCT03551418 | AHC IRB 6884 | June 9, 2018 | June 9, 2019 | June 9, 2020 | June 11, 2018 | June 28, 2018 |
|
|||
59 | NCT03698539 | Not yet recruiting | The Effect of Spontaneous Hand Gestures on Stuttering in Children With Down Syndrome |
|
|
Observational |
|
Other |
|
|
60 | All | 6 Years to 14 Years (Child) | NCT03698539 | s62049 | November 2018 | August 2019 | August 2020 | October 8, 2018 | October 9, 2018 | |||||
60 | NCT01394796 | Completed | Egcg, a dyrk1a Inhibitor as Therapeutic Tool for Reversing Cognitive Deficits in Down Syndrome Individuals. |
|
|
Interventional |
Phase 2 |
|
Other |
|
|
31 | All | 14 Years to 29 Years (Child, Adult) | NCT01394796 | EGCG/DYRC1A/DS/IMIM/1 | May 2010 | February 2011 | February 2011 | July 14, 2011 | March 13, 2013 | ||||
61 | NCT03677245 | Active, not recruiting | Balance Bike Training in Down Syndrome |
|
|
Interventional |
Not Applicable |
|
Other |
|
|
8 | All | 5 Years to 17 Years (Child) | NCT03677245 | 2018-0070 | November 26, 2018 | June 1, 2019 | June 1, 2019 | September 19, 2018 | December 11, 2018 |
|
|||
62 | NCT03764761 | Recruiting | Storybook Reading in Individuals With Down Syndrome |
|
|
Interventional |
Not Applicable |
|
Other / NIH |
|
|
15 | All | 7 Years to 35 Years (Child, Adult) | NCT03764761 | Storybook R01HD083381-01A1 |
April 1, 2018 | November 30, 2020 | November 30, 2020 | December 5, 2018 | December 5, 2018 |
|
|||
63 | NCT01667367 | Completed | A Molecular and Functional Brain Imaging Study in Individuals With Down Syndrome and Healthy Controls Following Single Dose RG1662 |
|
|
Interventional |
Phase 1 |
|
Industry |
|
|
13 | All | 18 Years to 40 Years (Adult) | NCT01667367 | BP25611 2012-001301-24 |
August 2012 | October 2013 | October 2013 | August 17, 2012 | September 2, 2015 |
|
|||
64 | NCT00675025 | Terminated | Evaluating The Safety Of Donepezil Hydrochloride (Aricept) For Up To 1 Year In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome - Follow-Up To A 10-Week, Double-Blind, Placebo-Controlled Trial |
|
|
Interventional |
Phase 2 |
|
Industry |
|
|
128 | All | 10 Years to 17 Years (Child) | NCT00675025 | E2020-A001-220 A2501060 |
April 2008 | February 2009 | May 8, 2008 | December 11, 2008 |
|
||||
65 | NCT03544840 | Not yet recruiting | Investigating Trunk Control in Young Children With Down Syndrome |
|
|
Interventional |
Not Applicable |
|
Other |
|
|
20 | All | 6 Months to 24 Months (Child) | NCT03544840 | 20067 | June 5, 2018 | June 5, 2018 | June 5, 2018 | June 4, 2018 | June 4, 2018 | ||||
66 | NCT02158390 | Completed | Phenotypic Specific Communication Intervention for Children With Down Syndrome |
|
|
Interventional |
Not Applicable |
|
Other |
|
|
78 | All | 30 Months to 54 Months (Child) | NCT02158390 | 05302014 | Merck | June 2014 | August 30, 2017 | February 6, 2018 | June 6, 2014 | July 12, 2018 |
|
||
67 | NCT02141971 | Completed | Down Syndrome Biomarker Initiative (DSBI) |
|
Observational |
|
Other / Industry |
|
|
12 | All | 30 Years to 60 Years (Adult) | NCT02141971 | DSBI | DSBI | June 1, 2013 | April 15, 2017 | April 15, 2017 | May 20, 2014 | May 2, 2017 |
|
||||
68 | NCT01832753 | Active, not recruiting | Treatment Trial of Subclinical Hypothyroidism in Down Syndrome |
|
|
Interventional |
Not Applicable |
|
Other / NIH |
|
|
12 | All | 8 Years to 20 Years (Child, Adult) | NCT01832753 | 12-009578 1R01HD071981-01A1 |
January 2013 | October 18, 2017 | July 1, 2019 | April 16, 2013 | October 8, 2018 |
|
|||
69 | NCT00864461 | Completed | Frequency of Metabolic Syndrome in Down Syndrome Patients |
|
Observational |
|
Other |
|
|
96 | All | 7 Years to 24 Years (Child, Adult) | NCT00864461 | 249-08 | September 1, 2009 | December 21, 2009 | March 31, 2010 | March 18, 2009 | May 5, 2017 |
|
|||||
70 | NCT03771469 | Recruiting | Validation of Sleep Questionnaires in the Down Syndrome Population |
|
|
Interventional |
Not Applicable |
|
Other |
|
|
60 | All | 2 Years to 17 Years (Child) | NCT03771469 | STUDY00018522 GOTOL0341A |
June 25, 2018 | September 2019 | April 2020 | December 11, 2018 | December 12, 2018 |
|
|||
71 | NCT02859389 | Recruiting | Neurocognitive and Psychosocial Outcomes in Survivors of Childhood Leukemia With Down Syndrome |
|
Observational |
|
Other |
|
|
80 | All | Child, Adult, Older Adult | NCT02859389 | DSCOG | August 18, 2016 | August 2019 | August 2019 | August 9, 2016 | September 11, 2018 |
|
|||||
72 | NCT03084497 | Completed | Effects of Infant Massage on Development of Down Syndrome Babies |
|
|
Interventional |
Not Applicable |
|
Other |
|
|
32 | All | 4 Months to 8 Months (Child) | NCT03084497 | USeville - EPinto | August 2016 | September 2016 | October 2016 | March 21, 2017 | March 21, 2017 |
|
|||
73 | NCT03778528 | Recruiting | Evaluation of Ocular Lens Proteins in Cataract From Individuals With Down Syndrome |
|
|
Observational |
|
Other |
|
|
20 | All | 1 Month to 18 Years (Child, Adult) | NCT03778528 | 17-0372 | May 30, 2018 | May 2020 | June 2020 | December 18, 2018 | December 18, 2018 |
|
||||
74 | NCT01778946 | Recruiting | Nicotine Treatment of Cognitive Decline in Down Syndrome |
|
|
Interventional |
Phase 1 Phase 2 |
|
Other |
|
|
15 | All | 25 Years and older (Adult, Older Adult) | NCT01778946 | 121759 | April 2013 | March 2018 | June 2018 | January 29, 2013 | June 26, 2017 |
|
|||
75 | NCT02304302 | Recruiting | Down Syndrome Memantine Follow-up Study |
|
|
Interventional |
Phase 2 |
|
Other |
|
|
200 | All | 15 Years to 32 Years (Child, Adult) | NCT02304302 | 121971 | October 2014 | November 2019 | December 2019 | December 1, 2014 | October 10, 2018 |
|
|||
76 | NCT02971254 | Recruiting | The Effects of Inhalational Anaesthetics in Cognitive Functions in Down Syndrome Patients |
|
|
Interventional |
Phase 2 |
|
Other |
|
|
39 | All | 16 Years to 75 Years (Child, Adult, Older Adult) | NCT02971254 | 8174/24.04.2013 | April 2013 | November 2017 | November 22, 2016 | July 19, 2017 |
|
||||
77 | NCT00959283 | Active, not recruiting | Study of Blood Samples From Newborns With Down Syndrome |
|
|
Observational |
|
Other / NIH |
|
180 | All | up to 90 Days (Child) | NCT00959283 | AAML08B1 NCI-2011-02193 CDR0000636115 COG-AAML08B1 U10CA098543 UG1CA189958 |
February 23, 2009 | December 30, 2011 | August 14, 2009 | August 7, 2018 |
|
||||||
78 | NCT00754052 | Terminated Has Results |
Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (Aricept) In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome, Aged 11 To 17 |
|
|
Interventional |
Phase 3 |
|
Industry |
|
|
8 | All | 11 Years to 17 Years (Child) | NCT00754052 | E2020-A001-335 A2501061 |
September 2008 | November 2008 | December 2008 | September 17, 2008 | April 23, 2018 | April 23, 2018 |
|
||
79 | NCT02651493 | Recruiting | Digital Dysmorphology Project |
|
|
Interventional |
Not Applicable |
|
Other |
|
|
750 | All | up to 18 Years (Child, Adult) | NCT02651493 | Pro00003506. | February 2013 | December 2023 | December 2023 | January 11, 2016 | January 4, 2019 |
|
|||
80 | NCT00287417 | Completed | Early Ultrasound and Maternal Biochemical Markers to Evaluate the Risk of Down Syndrome During the First Trimester |
|
|
Observational |
|
Other |
|
20000 | Female | 18 Years and older (Adult, Older Adult) | NCT00287417 | 3032 | July 2003 | February 2011 | February 6, 2006 | May 16, 2011 |
|
||||||
81 | NCT01684670 | Completed | Intensive Dysarthria Sessions in Adults and Children With Down Syndrome |
|
|
Interventional |
Not Applicable |
|
Other |
|
|
5 | All | 8 Years and older (Child, Adult, Older Adult) | NCT01684670 | Pro00039730 | February 2014 | May 2016 | May 2016 | September 13, 2012 | November 23, 2016 |
|
|||
82 | NCT00056329 | Unknown † | Vitamin E in Aging Persons With Down Syndrome |
|
|
Interventional |
Phase 3 |
|
Other / NIH |
|
|
350 | All | 50 Years and older (Adult, Older Adult) | NCT00056329 | IA0039 R01AG016381 NIA Grant AG16381 |
April 2002 | May 2012 | May 2012 | March 12, 2003 | May 4, 2012 |
|
|||
83 | NCT01580384 | Completed | A Non-Drug Study of The Suitability of Neurocognitive Tests And Functioning Scales For The Measurement of Cognitive And Functioning Changes in Individuals With Down Syndrome |
|
Observational |
|
Industry |
|
|
90 | All | 12 Years to 30 Years (Child, Adult) | NCT01580384 | BP25612 | February 2012 | January 2014 | January 2014 | April 19, 2012 | March 3, 2015 |
|
|||||
84 | NCT00754013 | Terminated Has Results |
Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (Aricept) In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome, Aged 6 To 10 |
|
|
Interventional |
Phase 3 |
|
Industry |
|
|
9 | All | 6 Years to 10 Years (Child) | NCT00754013 | E2020-A001-336 A2501061 |
September 2008 | October 2008 | December 2008 | September 17, 2008 | March 21, 2017 | February 13, 2013 |
|
||
85 | NCT01808508 | Completed Has Results |
Obstructive Sleep Apnea and Neurocognitive and Cardiovascular Function in Children With Down Syndrome |
|
|
Interventional |
Not Applicable |
|
Other |
|
|
27 | All | 8 Years to 20 Years (Child, Adult) | NCT01808508 | 11-007964 | TRIO | September 2010 | March 2014 | September 2014 | March 11, 2013 | February 8, 2016 | February 8, 2016 |
|
|
86 | NCT02759887 | Recruiting | Relationship Between Down Syndrome (DS) and Alzheimer's Disease (AD) |
|
|
Interventional |
Not Applicable |
|
Other |
|
|
40 | All | 21 Years and older (Adult, Older Adult) | NCT02759887 | PHX-16-0028-70-03 | November 2016 | March 2019 | June 2019 | May 3, 2016 | November 3, 2016 |
|
|||
87 | NCT01902407 | Enrolling by invitation | Computer Models of Airways in Children and Young Adults With Sleep Apnea and Down Syndrome |
|
Observational |
|
Other / NIH |
|
|
73 | All | 1 Year to 90 Years (Child, Adult, Older Adult) | NCT01902407 | CIN001-Dymosa R01HL105206-01 |
DYMOSA | March 2011 | December 2027 | December 2027 | July 18, 2013 | July 24, 2018 |
|
||||
88 | NCT03687866 | Active, not recruiting | Non-invasive Screening of Fetal Trisomy 21 by Digital PCR |
|
|
Observational |
|
Other |
|
|
776 | Female | 18 Years and older (Adult, Older Adult) | NCT03687866 | 14-048 | dPNI-T21 | January 2013 | September 2015 | December 2018 | September 27, 2018 | September 27, 2018 |
|
|||
89 | NCT00394290 | Unknown † | Down Syndrome and Continuous Positive Pressure Therapy |
|
|
Interventional |
Not Applicable |
|
Other |
|
|
30 | All | 18 Years and older (Adult, Older Adult) | NCT00394290 | IJL-PPC-EP02 Morphee |
Morphee | November 2006 | October 2012 | December 2012 | November 1, 2006 | October 19, 2012 |
|
||
90 | NCT03210675 | Recruiting | Early Detection and Treatment of Respiratory Sleep Disorders in Children With Down Syndrome |
|
|
Interventional |
Not Applicable |
|
Other |
|
|
80 | All | 6 Months to 3 Years (Child) | NCT03210675 | DP-TRS-T21 | RESPIRE21 | July 31, 2017 | December 2022 | December 2022 | July 7, 2017 | March 7, 2018 |
|
||
91 | NCT00965835 | Unknown † | Amyloid Plaque and Tangle Imaging in Alzheimer's Disease and Down Syndrome |
|
Observational |
|
NIH |
|
40 | All | 21 Years and older (Adult, Older Adult) | NCT00965835 | IA0166 1R21AG030681-01A2 |
August 2009 | May 2011 | May 2011 | August 26, 2009 | December 29, 2009 |
|
||||||
92 | NCT00966017 | Unknown † | Glucose Metabolic, Amyloid, and Tau Brain Imaging in Down Syndrome and Dementia |
|
Observational |
|
NIH |
|
108 | All | 45 Years and older (Adult, Older Adult) | NCT00966017 | IA0167 1R01AG033015-01 |
July 2009 | February 2014 | February 2014 | August 26, 2009 | December 29, 2009 |
|
||||||
93 | NCT01725438 | Active, not recruiting | Non Invasive Prenatal Diagnosis of Trisomy 21 by Genetic Analysis of Circulating Fetal Cells |
|
|
Interventional |
Not Applicable |
|
Other / Industry |
|
|
150 | All | 18 Years and older (Adult, Older Adult) | NCT01725438 | AOM10123 P100118 |
ISETTRI21 | June 19, 2012 | March 31, 2017 | December 31, 2017 | November 12, 2012 | December 8, 2017 |
|
||
94 | NCT00877292 | Completed | A New Prenatal Blood Test for Down Syndrome |
|
Observational |
|
Other / Industry |
|
|
4664 | Female | 18 Years and older (Adult, Older Adult) | NCT00877292 | 09-0004 | RNA | February 2009 | January 2011 | May 2011 | April 7, 2009 | June 3, 2015 |
|
||||
95 | NCT02344108 | Recruiting | A Pilot Study to Evaluate the Hypoglossal Nerve Stimulator in Adolescents With Down Syndrome and Obstructive Sleep Apnea |
|
|
Interventional |
Not Applicable |
|
Other / Industry |
|
|
50 | All | 10 Years to 21 Years (Child, Adult) | NCT02344108 | 14-146H | February 2015 | June 30, 2019 | September 30, 2020 | January 22, 2015 | December 6, 2018 |
|
|||
96 | NCT00378456 | Completed | Vitamins and Minerals for Children With Downs Syndrome |
|
|
Interventional |
Not Applicable |
|
Other |
|
All | up to 7 Months (Child) | NCT00378456 | 98CH11 | September 20, 2006 | September 20, 2006 |
|
||||||||
97 | NCT00240760 | Unknown † | Memantine and Down's Syndrome |
|
|
Interventional |
Not Applicable |
|
Other |
|
|
180 | All | 18 Years and older (Adult, Older Adult) | NCT00240760 | KCL/DS/MEM/1 EUDRACT- 2005 000381 39 ISRCTN47562898 |
October 2005 | October 18, 2005 | February 20, 2006 |
|
|||||
98 | NCT03135236 | Completed | Parents as the Primary Sexuality Educators for Their Young Adults With Down Syndrome |
|
|
Interventional |
Not Applicable |
|
Other |
|
|
13 | All | Child, Adult, Older Adult | NCT03135236 | AdvocateHC | March 6, 2017 | September 30, 2017 | June 1, 2018 | May 1, 2017 | June 18, 2018 |
|
|||
99 | NCT00928304 | Completed Has Results |
Phase II Study of Florbetaben (BAY94-9172) PET Imaging for Detection/Exclusion of Cerebral β-amyloid. |
|
|
Interventional |
Phase 2 |
|
Industry |
|
|
109 | All | 21 Years and older (Adult, Older Adult) | NCT00928304 | 14311 | June 2009 | January 2011 | January 2011 | June 25, 2009 | March 5, 2014 | January 28, 2014 |
|
||
100 | NCT03286634 | Recruiting | ASIA Down Syndrome Acute Lymphoblastic Leukemia 2016 |
|
|
Interventional |
Phase 2 |
|
Other |
|
|
60 | All | up to 20 Years (Child, Adult) | NCT03286634 | ASIA-DS-ALL-2016 | April 18, 2018 | March 31, 2028 | March 31, 2033 | September 18, 2017 | August 20, 2018 |
|
† Study has passed its completion date and status has not been verified in more than two years.