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44 studies found for:    "Diamond-Blackfan anemia"
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Study Details
Participant Details
Identifiers
Dates
Rank Status Study
1 Recruiting Safety and Efficacy Study of Sotatercept in Adults With Transfusion Dependent Diamond Blackfan Anemia
Condition: Diamond Blackfan Anemia
Interventions: Drug: Sotatercept;   Drug: Sotatercept with prednisone boost
2 Completed Mobilization of Stem Cells With G-CSF for Collection From Patients With Diamond-Blackfan Anemia
Condition: Diamond Blackfan Anemia
Interventions: Drug: G-CSF;   Procedure: Leukapheresis
3 Recruiting L-leucine in Diamond Blackfan Anemia Patients
Condition: Diamond Blackfan Anemia
Intervention: Drug: L-leucine
4 Recruiting A Pilot, Phase I/II Study of the Amino Acid Leucine in the Treatment of Patients With Transfusion-Dependent Diamond Blackfan Anemia
Conditions: Diamond Blackfan Anemia;   Blackfan Diamond Syndrome;   DBA;   Congenital Hypoplastic Anemia;   Pure Red Cell Aplasia
Intervention: Drug: leucine
5 Completed Medical Treatment for Diamond Blackfan Anemia
Conditions: Fanconi's Anemia;   Hematologic Disease
Interventions: Drug: Antithymocyte globulin;   Drug: Cyclosporine
6 Recruiting Diamond Blackfan Anemia Registry (DBAR)
Conditions: Anemia;   Blood Disease
Intervention:
7 Terminated
Has Results
A Study to Determine Whether Therapy With Daclizumab Will Benefit Patients With Bone Marrow Failure
Conditions: Aplastic Anemia;   Pure Red Cell Aplasia;   Diamond Blackfan Anemia
Intervention: Drug: Daclizumab
8 Completed
Has Results
Rituximab to Treat Moderate Aplastic Anemia, Pure Red Cell Aplasia, or Diamond Blackfan Anemia
Conditions: Anemia, Aplastic;   Red-Cell Aplasia, Pure;   Anemia, Diamond-Blackfan
Intervention: Drug: Rituximab
9 Recruiting Stem Cell Transplant for Patients With Sickle Cell Disease (SCD), Thalassemia, Diamond Blackfan Anemia (DBA) and Other Non-malignant (Non-cancerous) Hematologic Disorders
Conditions: Sickle Cell Disease;   Thalassemia;   Diamond Blackfan Anemia;   Non-malignant Hematologic Disorders
Interventions: Drug: Anti-thymocyte globulin (ATG);   Drug: Fludarabine monophosphate;   Drug: Busulfan;   Drug: Alemtuzumab;   Drug: Cyclophosphamide;   Drug: Mesna;   Radiation: total body irradiation
10 Unknown  Pilot Lenalidomide in Adult Diamond-Blackfan Anemia Patients w/ RBC Transfusion-Dependent Anemia
Conditions: Anemia;   Leukemia;   Leukemia, Myelocytic, Acute;   Dysmyelopoietic Syndromes
Intervention: Drug: Lenalidomide
11 Recruiting Improving the Results of Bone Marrow Transplantation for Patients With Severe Congenital Anemias
Conditions: Congenital Hemolytic Anemia;   Diamond-Blackfan Anemia
Interventions: Procedure: Radiotherapy;   Drug: Alemtuzumab (Campath );   Drug: Sirolimus (Rapamune )
12 Completed
Has Results
Stem Cell Transplant for Bone Marrow Failure Syndromes
Conditions: Diamond-Blackfan Anemia;   Kostmann's Neutropenia;   Shwachman-Diamond Syndrome
Interventions: Procedure: Stem cell transplant;   Drug: Fludarabine monophosphate;   Procedure: Total lymphoid irradiation;   Drug: Busulfan;   Biological: anti-thymocyte globulin
13 Unknown  Multi-Center Study of Iron Overload: Survey Study (MCSIO)
Conditions: Sickle Cell Disease;   Thalassemia;   Diamond-Blackfan Anemia
Intervention:
14 Unknown  Multi-Center Study of Iron Overload: Pilot Study
Conditions: Sickle Cell Disease;   Thalassemia;   Diamond-Blackfan Anemia
Intervention:
15 Terminated Allo-HCT MUD for Non-malignant Red Blood Cell (RBC) Disorders: Sickle Cell, Thal, and DBA: Reduced Intensity Conditioning, Co-tx MSCs
Conditions: Sickle Cell Disease;   Thalassemia;   Diamond-Blackfan Anemia
Interventions: Procedure: Bone marrow transplantation;   Biological: Mesenchymal Stromal Cells
16 Completed
Has Results
Partially Matched Stem Cell Transplantation for Patients With Refractory Severe Aplastic Anemia or Refractory Cytopenias
Conditions: Anemia, Aplastic;   Amegakaryocytic Thrombocytopenia;   Diamond-Blackfan Anemia;   Kostmann Syndrome
Intervention: Device: Allogeneic stem cell transplant
17 Completed
Has Results
Expanded Access of Deferasirox to Patients With Congenital Disorders of Red Blood Cells and Chronic Iron Overload
Conditions: Thalassemia;   Sickle Cell Disease;   Diamond Blackfan Anemia;   Myelofibrosis
Intervention: Drug: Deferasirox
18 Completed
Has Results
Alemtuzumab, Fludarabine, and Busulfan Followed By Donor Stem Cell Transplant in Treating Young Patients With Hematologic Disorders
Conditions: Congenital Amegakaryocytic Thrombocytopenia;   Diamond-blackfan Anemia;   Leukemia;   Myelodysplastic Syndromes;   Severe Congenital Neutropenia
Interventions: Biological: alemtuzumab;   Drug: busulfan;   Drug: cyclosporine;   Drug: fludarabine phosphate;   Drug: methotrexate;   Drug: methylprednisolone;   Procedure: allogeneic bone marrow transplantation;   Procedure: allogeneic hematopoietic stem cell transplantation;   Procedure: peripheral blood stem cell transplantation;   Procedure: umbilical cord blood transplantation
19 Active, not recruiting Stem Cell Transplant for Hemoglobinopathy
Conditions: Sickle Cell Disease;   Thalassemia;   Severe Congenital Neutropenia;   Diamond-Blackfan Anemia;   Shwachman-Diamond Syndrome
Interventions: Drug: Busulfan, Fludarabine, ATG, TLI;   Drug: Busulfan, Cyclophosphamide, ATG, GCSF;   Drug: Campath, Fludarabine, Cyclophosphamide;   Radiation: Total Body Irradiation;   Procedure: Stem cell infusion
20 Completed Busulfan, Antithymocyte Globulin, and Fludarabine Followed By a Donor Stem Cell Transplant in Treating Young Patients With Blood Disorders, Bone Marrow Disorders, Chronic Myelogenous Leukemia in First Chronic Phase, or Acute Myeloid Leukemia in First Remission
Conditions: Congenital Amegakaryocytic Thrombocytopenia;   Diamond-blackfan Anemia;   Fanconi Anemia;   Leukemia;   Severe Congenital Neutropenia;   Thrombocytopenia
Interventions: Biological: anti-thymocyte globulin;   Drug: busulfan;   Drug: fludarabine phosphate;   Procedure: allogeneic bone marrow transplantation;   Procedure: peripheral blood stem cell transplantation;   Procedure: umbilical cord blood transplantation;   Radiation: radiation therapy

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Study has passed its completion date and status has not been verified in more than two years.