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33 studies found for:    "Devic disease"

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Rank Status Study
1 Unknown † Autologous Mesenchymal Stem Cells for the Treatment of Neuromyelitis Optica Spectrum Disorders
Conditions: Devic's Syndrome;   Devic's Neuromyelitis Optica;   Devic Syndrome;   Devic's Disease;   Devic Disease
Intervention: Biological: Autologous mesenchymal stem cells
2 Completed
Has Results 		An Open Label Study of the Effects of Eculizumab in Neuromyelitis Optica
Conditions: Neuromyelitis Optica;   Devic's Disease
Intervention: Drug: Eculizumab
3 Recruiting Hematopoietic Stem Cell Transplant in Devic's Disease
Condition: Devic's Disease
Intervention: Procedure: Hematopoietic stem cell transplantation
4 Recruiting A Longitudinal Study of Neuromyelitis Optica and Transverse Myelitis
Conditions: Neuromyelitis Optica;   Neuromyelitis Optica Spectrum Disorder;   Transverse Myelitis;   Optic Neuritis
Intervention:
5 Unknown † Efficacy and Safety of Mitoxantrone in Patients With Refractory Neuromyelitis Optica and Spectrum Disorders
Conditions: Neuromyelitis Optica;   Neuromyelitis Optica Spectrum Disorders
Intervention: Drug: Mitoxantrone
6 Recruiting Ublituximab for Acute Neuromyelitis Optica (NMO) Relapses
Conditions: Neuromyelitis Optica;   Neuromyelitis Optica Spectrum Disorder
Intervention: Drug: Ublituximab
7 Recruiting The French Cohort and Biobank of Devic's Neuromyelitis Optica and Related Neurological Disorders (NMOSD) (NOMADMUS)
Conditions: Neuromyelitis Optica Spectrum Disorders;   Neuromyelitis Optica Spectrum Related Disorders
Intervention:
8 Active, not recruiting Autologous Hematopoietic Stem Cell Transplant in Neuromyelitis Optica
Condition: Neuromyelitis Optica
Intervention: Procedure: AHSCT
9 Completed
Has Results 		C1-esterase Inhibitor (Cinryze) for Acute Treatment of Neuromyelitis Optica Exacerbation
Condition: Neuromyelitis Optica
Intervention: Drug: C1-esterase inhibitor (Cinryze)
10 Active, not recruiting Maintenance Plasma Exchange for Neuromyelitis Optica
Conditions: Neuromyelitis Optica;   Neuromyelitis Optica Spectrum Disorder;   Recurrent Idiopathic Longitudinally Extensive Transverse Myelitis
Intervention: Procedure: Plasma exchange (PLEX)
11 Completed A Pilot Study of Mitoxantrone for the Treatment of Recurrent Neuromyelitis Optica (Devic’s Disease)
Conditions: Neuromyelitis Optica;   Myelitis, Transverse;   Demyelinating Autoimmune Diseases, CNS;   Autoimmune Diseases of the Nervous System
Intervention: Drug: Mitoxantrone
12 Recruiting A Double Blind Trial To Evaluate The Safety And Efficacy Of Eculizumab In Relapsing NMO Patients (PREVENT Study)
Conditions: Neuromyelitis Optica;   Neuromyelitis Optica Spectrum Disorder
Intervention: Drug: Eculizumab
13 Completed Neuromyelitis Optica (NMO) & Cetirizine
Condition: Neuromyelitis Optica
Intervention: Drug: cetirizine
14 Enrolling by invitation An Open Label Extension Trial of Eculizumab in Relapsing NMO Patients
Conditions: Neuromyelitis Optica;   Neuromyelitis Optica Spectrum Disorder
Intervention: Biological: eculizumab
15 Unknown † Pilot Study of alpha1-antitrypsin to Treat Neuromyelitis Optica Relapses
Condition: Neuromyelitis Optica
Interventions: Drug: Alpha1-antitrypsin;   Drug: methylprednisolone
16 Recruiting Phase II Clinical Trial of NPB-01 in Patients With Anti-aquaporin 4 Antibody Positive Neuromyelitis Optica Spectrum Disorder Not Provided Adequate Effect of Therapy to Steroids Plus Therapy.
Condition: Neuromyelitis Optica Spectrum Disorder
Intervention: Drug: NPB-01
17 Completed Safety and Tolerability of Rituximab in Neuromyelitis Optica
Condition: Neuromyelitis Optica
Intervention: Drug: Rituximab
18 Unknown † Safety and Efficacy of Umbilical Cord Mesenchymal Stem Cell Therapy for Patients With Progressive Multiple Sclerosis and Neuromyelitis Optica
Conditions: Progressive Multiple Sclerosis;   Neuromyelitis Optica.
Intervention: Biological: human umbilical cord mesenchymal stem cells
19 Active, not recruiting Efficacy and Safety of Bortezomib as add-on Treatment in Relapsing Neuromyelitis Optica Spectrum Disorder
Condition: Neuromyelitis Optica Spectrum Disorder
Intervention: Drug: Bortezomib
20 Recruiting Multimodel Magnetic Resonance Imaging (MRI)of Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders
Conditions: Multiple Sclerosis;   Neuromyelitis Optica Spectrum Disorders
Intervention: Other: Magnetic Resonance Imaging
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† Indicates status has not been verified in more than two years