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46 studies found for:    "Colorectal Neoplasms, Hereditary Nonpolyposis"
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Rank Status Study
1 Not yet recruiting Mesalamine for Colorectal Cancer Prevention Program in Lynch Syndrome
Condition: Colorectal Neoplasms, Hereditary Nonpolyposis
Interventions: Drug: Mesalamine 1600 mg QD;   Drug: Mesalamine 3200 mg QD;   Drug: Placebo
2 Recruiting Pancreatic Cancer Screening of High-Risk Individuals in Arkansas
Conditions: Pancreatic Neoplasms;   Peutz-Jegher's Syndrome;   BRCA1 Gene Mutation;   BRCA2 Gene Mutation;   Ataxia Telangiectasia;   Familial Atypical Mole-Malignant Melanoma Syndrome;   Colorectal Neoplasms, Hereditary Nonpolyposis;   Hereditary Pancreatitis
Interventions: Other: Pancreatic Cancer Screening Pathway 1;   Other: Pancreatic Cancer Screening Pathway 2
3 Enrolling by invitation Implementation of Guidelines on Hereditary or Familial Colorectal Cancer
Condition: Colorectal Neoplasms, Hereditary Nonpolyposis
Interventions: Other: Implementation aids;   Other: Control
4 Completed Magnification Narrow Band Imaging Colonoscopy for Hereditary Non-Polyposis Colorectal Cancer Surveillance
Condition: Colorectal Neoplasms, Hereditary Nonpolyposis
Intervention: Procedure: Narrow Band Imaging
5 Completed CHROENDOHNPCC: Early Detection of Pre-cancer Lesions in Adults With Hereditary Nonpolyposis Colorectal Cancer Syndrome
Condition: Colorectal Neoplasms, Hereditary Nonpolyposis
Intervention: Procedure: Colonoscopy with chromoscopy
6 Not yet recruiting Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair or Microsatellite Instability
Conditions: Colon Adenocarcinoma;   DNA Repair Disorder;   Lynch Syndrome;   Microsatellite Instability;   Stage IIIA Colon Cancer;   Stage IIIB Colon Cancer;   Stage IIIC Colon Cancer
Interventions: Drug: Atezolizumab;   Drug: Fluorouracil;   Other: Laboratory Biomarker Analysis;   Drug: Leucovorin Calcium;   Drug: Oxaliplatin;   Other: Quality-of-Life Assessment
7 Not yet recruiting Effect of Chemoprevention by Low-dose Aspirin of New or Recurrent Colorectal Adenomas in Patients With Lynch Syndrome
Condition: Lynch Syndrome
Interventions: Drug: Acetylsalicylic acid lysinate 300 mg;   Drug: Placebo (for Aspirin 300);   Drug: Acetylsalicylic acid lysinate 100 mg;   Drug: Placebo 100 (for Aspirin 100)
8 Enrolling by invitation Identifying Patients With Hereditary and Familial Colorectal Cancer by Using an Online Risk Tool
Conditions: Colorectal Cancer;   Lynch Syndrome;   Familial Colorectal Cancer
Intervention: Other: Offering an online risk assessment questionnaire
9 Recruiting NBI Versus Indigo Carmine During Colonoscopy in Lynch Syndrome
Condition: Lynch Syndrome
Intervention: Procedure: Colonoscopy
10 Not yet recruiting Finding the Best Dose of Aspirin to Prevent Lynch Syndrome Cancers
Condition: Lynch Syndrome I (Site-specific Colonic Cancer)
Intervention: Drug: Aspirin
11 Recruiting Universal Screening for Lynch Syndrome in Women With Endometrial and Non-Serous Ovarian Cancer
Conditions: Lynch Syndrome;   Endometrial Neoplasms;   Ovarian Neoplasms;   Colorectal Neoplasms
Intervention: Behavioral: Questionnaire, Educational Material
12 Recruiting Metagenomic Evaluation of the Gut Microbiome in Patients With Lynch Syndrome and Other Hereditary Colonic Polyposis Syndromes
Conditions: Lynch Syndrome;   Hereditary Colonic Polyposis Syndromes
Interventions: Genetic: colonic biopsies;   Genetic: questionnaires
13 Recruiting Pancreatic Cancer Early Detection Program
Conditions: Pancreatic Cancer;   Pancreas Cancer;   Pancreatic Adenocarcinoma;   Familial Pancreatic Cancer;   BRCA 1/2;   HNPCC;   Lynch Syndrome;   Hereditary Pancreatitis;   FAMMM;   Familial Atypical Multiple Mole Melanoma;   Peutz Jeghers Syndrome
Interventions: Procedure: Endoscopic Ultrasound;   Procedure: Magnetic Resonance Imaging (MRI)
14 Recruiting Preliminary Evaluation of Septin9 in Patients With Hereditary Colon Cancer Syndromes
Conditions: Familial Adenomatous Polyposis;   Map Syndrome;   Lynch Syndrome;   Hnpcc;   Colorectal Cancer
Intervention: Other: Epi proColon Testing
15 Recruiting Prostate Cancer Screening Among Men With High Risk Genetic Predisposition
Conditions: BRCA1 Syndrome;   BRCA2 Syndrome;   Lynch Syndrome
Interventions: Other: PSA;   Other: IPSS questionnaire;   Other: DRE (Digital Rectal Examination );   Other: urine flow and residual;   Procedure: a multiparametric prostate MRI;   Procedure: trans-rectal ultra-sound guided prostate biopsy
16 Recruiting Naproxen in Preventing DNA Mismatch Repair Deficient Colorectal Cancer in Patients With Lynch Syndrome
Condition: Lynch Syndrome
Interventions: Other: Laboratory Biomarker Analysis;   Drug: Naproxen;   Other: Placebo
17 Recruiting Cancer Research Repository for Individuals With Cancer Diagnosis and High Risk Individuals.
Conditions: Pancreatic Cancer;   Thyroid Cancer;   Lung Cancer;   Esophageal Cancer;   Thymus Cancer;   Colon Cancer;   Rectal Cancer;   GIST;   Anal Cancer;   Bile Duct Cancer;   Duodenal Cancer;   Gallbladder Cancer;   Gastric Cancer;   Liver Cancer;   Small Intestine Cancer;   Peritoneal Surface Malignancies;   Familial Adenomatous Polyposis;   Lynch Syndrome;   Bladder Cancer;   Kidney Cancer;   Penile Cancer;   Prostate Cancer;   Testicular Cancer;   Ureter Cancer;   Urethral Cancer;   Hypopharyngeal Cancer;   Laryngeal Cancer;   Lip Cancer;   Oral Cavity Cancer;   Nasopharyngeal Cancer;   Oropharyngeal Cancer;   Paranasal Sinus Cancer;   Nasal Cavity Cancer;   Salivary Gland Cancer;   Skin Cancer;   CNS Tumor;   CNS Cancer;   Mesothelioma
18 Recruiting The Cancer of the Pancreas Screening-5 CAPS5)Study
Conditions: Pancreas Cancer;   Peutz-Jeghers Syndrome;   Gene Mutation;   Germline Mutation Carrier;   Lynch Syndrome
Intervention: Drug: Human synthetic secretin
19 Active, not recruiting Dendritic Cell Vaccination in Patients With Lynch Syndrome or Colorectal Cancer With MSI
Condition: Colorectal Cancer
Intervention: Biological: DC vaccination
20 Recruiting Ohio Colorectal Cancer Prevention Initiative
Conditions: Lynch Syndrome;   Colorectal Cancer
Interventions: Genetic: LS tumor screening;   Genetic: Genetic testing;   Behavioral: Genetic Counseling;   Other: Biorepository;   Behavioral: Questionnaire

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