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21 studies found for:    "Ancylostomiasis"
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Rank Status Study
1 Completed Study of Na-ASP-2 Human Hookworm Vaccine in Healthy Adults Without Evidence of Hookworm Infection
Condition: Hookworm Infection
Interventions: Biological: Na-ASP-2/Alhydrogel Hookworm Vaccine;   Biological: Saline placebo
2 Completed Prevalence of Hookworm Infection and Community Preparedness for Hookworm Vaccine Trials in Endemic Areas of Brazil
Condition: Hookworm Infection
Intervention: Biological: Na-ASP-2 Skin Test Reagent
3 Active, not recruiting Hookworm Immune Regulation Project
Condition: Hookworm Infection
Intervention: Other: Blood and feces sampling
4 Terminated Phase 1 Trial of Na-ASP-2 Hookworm Vaccine in Previously Infected Brazilian Adults
Condition: Hookworm Infection
Intervention: Biological: Na-ASP-2 Hookworm Vaccine
5 Recruiting Experimental Infection of Hookworm-naïve Adults With Dermally-applied Infectious Necator Americanus Hookworm Larvae
Condition: Hookworm Infection
Intervention: Biological: Necator americanus Hookworm Larvae
6 Completed Study to Test Whether Shoes Protect Children Against Hookworm Infection on Pemba Island, Zanzibar
Condition: Hookworm
Intervention: Device: Shoes
7 Active, not recruiting Study of Na-APR-1 (M74)/Alhydrogel® Co-administered With Na-GST-1/Alhydrogel in Brazilian Adults
Conditions: Hookworm Infection;   Hookworm Disease
Interventions: Biological: Na-GST-1/Alhydrogel plus GLA-AF;   Biological: Na-APR-1 (M74)/Alhydrogel;   Biological: Na-APR-1 (M74)/Alhydrogel plus GLA-AF;   Biological: Sterile Saline Placebo
8 Completed Safety and Immunogenicity Study of Na-GST-1 With or Without CpG
Conditions: Hookworm Infection;   Hookworm Disease
Interventions: Biological: Na-GST-1/Alhydrogel®;   Biological: CpG 10104
9 Completed Safety and Immunogenicity of Co-Administered Hookworm Vaccine Candidates Na-GST-1 and Na-APR-1 in Gabonese Adults
Conditions: Hookworm Infection;   Hookworm Disease
Interventions: Biological: Na-APR-1 (M74)/Alhydrogel®;   Biological: Na-GST-1/Alhydrogel®;   Biological: Hepatitis B vaccine
10 Completed Safety and Immunogenicity of the Na-APR-1 Hookworm Vaccine in Healthy Adults
Conditions: Hookworm Infection;   Hookworm Disease
Interventions: Biological: Na-APR-1 (M74)/Alhydrogel®;   Biological: Gluco-Pyranosylphospho-Lipid A Aqueous Formulation
11 Completed
Has Results
Safety and Immunogenicity of a Human Hookworm Candidate Vaccine With Different Doses of a Novel Adjuvant
Conditions: Hookworm Infection;   Hookworm Disease
Interventions: Biological: 10 μg Na-GST-1/Alhydrogel;   Biological: 30 μg Na-GST-1/Alhydrogel;   Biological: 100 μg Na-GST-1/Alhydrogel;   Biological: 10 μg Na-GST-1/Alhydrogel/GLA-AF (1 μg);   Biological: 30 μg Na-GST-1/Alhydrogel/GLA-AF (1 μg);   Biological: 30 μg Na-GST-1/Alhydrogel/GLA-AF (5 μg);   Biological: 100 μg Na-GST-1/Alhydrogel/GLA-AF (5 μg)
12 Completed Safety and Immunogenicity of a Human Hookworm Candidate Vaccine With or Without Additional Adjuvant in Brazilian Adults
Conditions: Hookworm Infection;   Hookworm Disease
Interventions: Biological: 10 μg Na-GST-1/Alhydrogel;   Biological: 30 μg Na-GST-1/Alhydrogel;   Biological: 100 μg Na-GST-1/Alhydrogel;   Biological: 10 μg Na-GST-1/ Alhydrogel/GLA-AF;   Biological: 30 μg Na-GST-1/Alhydrogel/GLA-AF;   Biological: 100 μg Na-GST-1/Alhydrogel/GLA-AF;   Biological: Butang® hepatitis B vaccine
13 Completed
Has Results
Development of a Skin Test for the Na-ASP-2 Hookworm Antigen
Conditions: Hookworm Infection;   Allergy
Intervention: Biological: Na-ASP-2 Skin Test Reagent
14 Recruiting Study of Co-administered Na-APR-1 (M74) and Na-GST-1 in Gabonese Children
Conditions: Hookworm Disease;   Hookworm Infection
Interventions: Biological: Na-GST-1/Alhydrogel;   Biological: Na-APR-1 (M74)/Alhydrogel;   Biological: Hepatitis B Vaccine
15 Completed Randomised Placebo Controlled Study of Effects of Therapeutic Hookworm Infection in Asthma
Condition: Asthma
Intervention: Procedure: Infection with hookworm larvae
16 Recruiting Establishing a Controlled Human Hookworm Infection Model at Leiden University Medical Center
Condition: Necator Americanus Infection
Intervention: Biological: Necator americanus L3 larvae
17 Completed Randomised Controlled Clinical Trials of the Effect of Therapeutic Hookworm Infection in Allergic Rhinoconjunctivitis
Conditions: Rhinitis, Allergic, Perennial;   Hayfever;   Allergy
Intervention: Procedure: Infection with hookworm larvae
18 Completed Iron Absorption and Utilization in Adolescents Infected With Malaria Parasites, Hookworms or Schistosoma
Conditions: Malaria, Falciparum;   Hookworm Infections;   Schistosoma Haematobium
Intervention: Dietary Supplement: Fe-57 orally, Fe-58 intravenously
19 Not yet recruiting Hookworm Therapy for Coeliac Disease
Condition: Celiac Disease
Interventions: Other: Gluten micro-challenge;   Other: Inadvertent gluten challenge;   Other: Moderate gluten challenge;   Other: Liberal diet;   Other: Necator americanus-hookworm larvae L3-10;   Other: Tabasco® Sauce;   Other: Necator americanus-hookworm larvae L3-20;   Other: Gluten free diet
20 Unknown  Does Treating Hookworm Improve Productivity of Small Subsistence Farmers
Conditions: Hookworm Stool Burden;   Anemia;   Exercise Tolerance
Interventions: Drug: albendazole;   Drug: placebo

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Study has passed its completion date and status has not been verified in more than two years.