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67 studies found for:    "Alpha 1-antitrypsin deficiency"
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Rank Status Study
1 Completed The Use of High Resolution Chest Computed Tomography in Alpha-1 Antitrypsin Deficiency
Condition: Alpha-1 Antitrypsin Deficiency
Intervention:
2 Recruiting Alpha-1 Antitrypsin Deficiency Adult Liver Study
Condition: Alpha-1 Antitrypsin Deficiency
Intervention: Procedure: Liver Biopsy
3 Not yet recruiting Microbioma in Sputa From COPD With Alpha-1 Antitrypsin Deficiency
Condition: Alpha-1 Antitrypsin Deficiency
Intervention: Other: collection of sputum
4 Recruiting A Study of ARC-AAT in Healthy Volunteer Subjects and Patients With Alpha-1 Antitrypsin Deficiency (AATD)
Condition: Alpha-1 Antitrypsin Deficiency
Interventions: Drug: ARC-AAT Injection;   Other: Placebo
5 Completed
Has Results
Safety & Efficacy Study of rAAV1-CB-hAAT for Alpha-1 Antitrypsin Deficiency
Condition: Alpha-1 Antitrypsin Deficiency
Intervention: Drug: rAAV1-CB-hAAT
6 Recruiting Epigenetic Regulation of Immunity in Alpha-1 Anti-trypsin Deficiency
Condition: Alpha 1-Antitrypsin Deficiency
Intervention:
7 Recruiting Safety and Pharmacokinetics of Alpha-1 MP in Patients With Alpha1-Antitrypsin Deficiency
Condition: Alpha1-Antitrypsin Deficiency
Intervention: Biological: Alpha-1 MP
8 Completed Safety Study of an Aerosolized, Recombinant Alpha 1-Antitrypsin in Subjects With Alpha 1-Antitrypsin Deficiency
Condition: Alpha 1-antitrypsin Deficiency
Intervention: Drug: Aerosolized, Recombinant Alpha 1-Antitrypsin
9 Completed Phase II/III Study of an Alpha-1 Proteinase Inhibitor (Kamada-API) in Individuals With Alpha-1 Antitrypsin Deficiency
Condition: Alpha 1-Antitrypsin Deficiency
Intervention: Drug: Kamada-API
10 Enrolling by invitation Long-term Safety of Alpha1-Proteinase Inhibitor (Human) in Japanese Subjects With Alpha1 Antitrypsin Deficiency (GTI1401-OLE)
Condition: Alpha1-Antitrypsin Deficiency
Intervention: Biological: Alpha-1 MP
11 Completed Study of the Effect of Aerosolized, Recombinant Alpha 1-Antitrypsin on Epithelial Lining Fluid Analytes in Subjects With Alpha 1-Antitrypsin Deficiency
Condition: Alpha 1-Antitrypsin Deficiency
Intervention: Drug: Aerosolized, Recombinant Alpha 1-Antitrypsin
12 Completed Genomic Research in Alpha-1 Antitrypsin Deficiency
Conditions: Alpha 1 Antitrypsin Deficiency;   AATD
Intervention:
13 Recruiting Liver Disease in Patients With alpha1-antitrypsin Deficiency
Condition: alpha1-antitrypsin Deficiency
Intervention: Other: No intervention
14 Unknown  Endoscopic Lung Volume Reduction in Patients With Advanced Emphysema Due to alpha1 Antitrypsin Deficiency
Condition: Hereditary Emphysema (Alpha 1-antitrypsin Deficiency)
Intervention: Device: Implantation of intrabronchial valves (IBV) (Spiration IBV)
15 Terminated Study of Genotype and Phenotype in Patients With Alpha 1-Antitrypsin Deficiency
Condition: Alpha 1-Antitrypsin Deficiency
Intervention:
16 Enrolling by invitation Long Term Safety of Alpha1-Proteinase Inhibitor in Subjects With Alpha1 Antitrypsin Deficiency
Condition: Pulmonary Emphysema in Alpha-1 Antitrypsin Deficiency
Intervention: Biological: Alpha-1 MP
17 Completed
Has Results
Comparison of Pharmacokinetic, Safety, Tolerability of Alpha-1 MP and Prolastin In Alpha1-antitrypsin Deficient Adults
Condition: Alpha 1-Antitrypsin Deficiency
Interventions: Drug: Alpha-1 MP;   Drug: alpha-1 proteinase inhibitor (human)
18 Recruiting Carbamazepine in Severe Liver Disease Due to Alpha-1 Antitrypsin Deficiency
Conditions: Alpha-1-antitrypsin Deficiency;   Liver Cirrhosis
Interventions: Drug: Drug-Carbamazepine (Tegretol XR);   Drug: Carbamazepine (Tegretol XR) Placebo
19 Completed Experimental Gene Transfer Procedure to Treat Alpha 1-Antitrypsin Deficiency
Condition: Alpha 1-Antitrypsin Deficiency
Intervention: Biological: rAAV1-CB-hAAT
20 Active, not recruiting Experimental Gene Transfer Procedure to Treat Alpha 1-Antitrypsin Deficiency
Condition: Alpha 1-Antitrypsin Deficiency
Intervention: Genetic: rAAV2-CB-hAAT Gene Vector

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Study has passed its completion date and status has not been verified in more than two years.